Identifiers and Description

Gene Model Identifier

TTHERM_00321680

Standard Name

CTH3 (CaTHepsin 3)

Aliases

PreTt15986 | 32.m00307

Description

CTH3 eukaryotic aspartyl protease

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• aspartic-type endopeptidase activity (IEA) | GO:0004190

Biological Process

• proteolysis (IEA) | GO:0006508

Domains

• ( PF00026 ) Eukaryotic aspartyl protease

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_10074.1	9.997093137033517e-262
	Description: eukaryotic aspartyl protease (453 aa)
Tetrahymena borealis	EI9_05944.1	9.997093137033517e-262
	Description: hypothetical protein (2350 aa)
WormBase	WBGene00000217	6.001182358613152e-70
	Description: locus:asp-4 status:Confirmed UniProt:Q21966 protein_id:CAA90633.1
WormBase	WBGene00001680	6.001182358613152e-70
	Description: locus:gpb-2 Guanine nucleotide-binding protein subunit beta-2 status:Confirmed UniProt:Q20636 protein_id:CAA95824.1
DictyBase	DDB_G0279411	2.9995010303521745e-64
	Description: ctsD on chromosome: 3 position 2104523 to 2105867
SGD	YPL154C	2.0008958828286524e-54
	Description: PEP4 Vacuolar aspartyl protease (proteinase A), required for the posttranslational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; synthesized as a zymogen, self-activates
Oxytricha	Contig18489.0.g67	6.999507172836373e-51
	Description: Eukaryotic aspartyl protease
Stentor Coeruleus	SteCoe_12876	8.985825944049381e-37
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00321680(coding)
ATGAGAAGAAGCTTGCTTACAGTAGCTCTCTTTGCAGTCTGTTTGCTTTCCTTCGCTATG
GCTGTCCATATTCGCAAGGATAAGCAACAAACCTTAGAATCAAAGGCTAAGTTATACTCT
GCTGAGGGAGATGAATTACATACAATCTCACTTAAAAAGATTCCATAAAGTCCTGGAGAA
AGAAGAAAGGCCATCGAGCTTCTCTCTACTGCCTAATACTATAGCTATAATAAGGATGAC
TACTCAGCTGAAAAAGATTTCATCTATACCCAATAGAAGGAAACATCTTTTACTAGCACT
AGCAGCAATTCTAAAACCTCTACTCATACAGTAAAGCTTTATAATTTCAAGAATGTTTAA
TACACTGGTGATTTAGCTATTGGCTCATCAGATAACGTTTTCTCTGTCATCTATGACACA
GGTTCAGCTAATATTTGGATGAATTCCATTCACTGCAATGACCCAGGTTGTGTAAGTCAC
AAGTAATACGATTTCCATCAATCAAAGAACTATAAAAGTGTTGGACTTTCCCTTGATGTT
CAATTTGGTACAGGTGAATTAATTGGTGAAATGGCTTAAGACACTGTTTATTTTGGTGAT
ATCGAAATTAAAGATTAGACTTTTGTCGAAATTCACGAGCAAAGAGGTGATGTTTTCGCT
CAGTCCAAGTTTGACGGTATTGTCGGTTTGGCTTTCCCTTCTATGGCTGCCTATAACAAG
AATCCCTTATTTGATAGCTTAATTGAACAAAAGAAAATTTAAAAAAATATCTTCTCCTTC
TATATGAGTCCACATGACGGTAGAACTGATTCTGAAATTTCTATTGGTGGTGCCAATCCT
TTAAGATATAGTGGTGAAATTAAATATCATAAAGTTAAGAAAGATTACTACTGGCTTATT
GAAGCTTAAAGCATCTTAGTTGGTGGAAAAGATGTTGGTCTTTGCAAAGGTGGTTGTTAC
GTTATTGCAGACACTGGTACTTCTCTTATTACTGGTCCTTCTGAAGACATCTTTACTTTA
TTAGATCACTCAAGTGTCAACACTAATTGCAGTAACGTTTCAGAATTACCTGAATTAACT
TTCGTCATCGATGGTGCCCACTATACATTAACAGGAGAAGAATATGTTTTATAAGAAAAC
TCTGATGGTTCTCAATAGACTGTTGAAACTGCTTAATCTAATGTTGAAATGAGCAGCTCC
ACTGCATAATGTATTGTTGCTTTCATGCCTCTTGATATTCCCAATGATGAAGAAAATTTC
CCTTATGAAAAAGCTTGGATTTTGGGAGATACTTTCTTACAAAAGTTTTATTCAATTTAT
GATAGAGACAATGACAGAGTTGGTTTTGCTTTGGCAAGACATTGA

>TTHERM_00321680(gene)
ATGAGAAGAAGCTTGCTTACAGTAGCTCTCTTTGCAGTCTGTTTGCTTTCCTTCGCTATG
GCTGTCCATATTCGCAAGGATAAGCAACAAACCTTAGAATCAAAGGCTAAGTTATACTCT
GCTGAGGGAGATGAATTACATACAATCTCACTTAAAAAGATTCCATAAAGTCCTGGAGAA
AGAAGAAAGGCCATCGAGCTTCTCTCTACTGCCTAATACTATAGCTATAATAAGGATGAC
TACTCAGCTGAAAAAGATTTCATCTATACCCAATAGAAGGAAACATCTTTTACTAGCACT
AGCAGCAATTCTAAAACCTCTACTCATACAGTAAAGCTTTATAATTTCAAGAATGTTTAA
TACACTGGTGATTTAGCTATTGGCTCATCAGATAACGTTTTCTCTGTCATCTATGACACA
GGTTCAGCTAATATTTGGATGAATTCCATTCACTGCAATGACCCAGGTTGTGTAAGTCAC
AAGTAATACGATTTCCATCAATCAAAGAACTATAAAAGTGTTGGACTTTCCCTTGATGTT
CAATTTGGTACAGGTGAATTAATTGGTGAAATGGCTTAAGACACTGTTTATTTTGGTGAT
ATCGAAATTAAAGATTAGACTTTTGTCGAAATTCACGAGCAAAGAGGTGATGTTTTCGCT
CAGGTATACTATAAATTTGATTAGCTTATTCAGCTATTTACGTTTTTAAATAAAAATATA
ACATCTTGCAAGATGTAATTTTTACATTCCAAAGCCTTCAGAAATATTTCAAGCCTACAA
AAAACGAAAATTTAAAGCCTATGGAAACAGTTTACATTGAAATATTTATATATTTATTTA
TACCTACCAAATATTAGCCAACAAATATTCAAAGCAAATAACAAGATTTTACAATATTAC
AGATGAAAAGTTGTTGTCCTAATCAAAATATCATTTTAGTTGTGGTTAATAATTCTTAGT
GTTTATTTCAAAAACGTCCAAAAAAATTATTGAATCAGTCAACCAGTCAGTCAGTTTTTG
ATTATTTCTCAAAAATGAATTTATAAATTTTAAATTAAAAATCATCAATAAAAGTAAAAA
AATGTAGAATTTTGTTCTAGTTTCAATTAAAAAATATAAAATAGAATTATTTGTTTCTTT
TGATTTTGAATTAAGAAACAAAATAATGATTTAGAGTTTCTTAATATTTAATAAAGAATT
TCAATCAATAAGGCGAGTTTTATTTAAAATGTCGATAGAACTATTTTTAGATTCTTTAAA
TTCATATTTAATTTATTATAAAAATATTAATTTAGTCCAAGTTTGACGGTATTGTCGGTT
TGGCTTTCCCTTCTATGGCTGCCTATAACAAGAATCCCTTATTTGATAGCTTAATTGAAC
AAAAGAAAATTTAAAAAAATATCTTCTCCTTCTATATGAGTCCACATGACGGTAGAACTG
ATTCTGAAATTTCTATTGGTGGTGCCAATCCTTTAAGATATAGTGGTGAAATTAAATATC
ATAAAGTTAAGAAAGATTACTACTGGCTTATTGAAGCTTAAAGCATCTTAGTTGGTGGAA
AAGATGTTGGTCTTTGCAAAGGTGGTTGTTACGTTATTGCAGACACTGGTACTTCTCTTA
TTACTGGTCCTTCTGAAGACATCTTTACTTTATTAGGTAAATATTGCAATTATCTTTCAT
GCTTTTACAAATATTGTTTCAAAATATTTATTAAATTTTACATTTAAATGAATTTAGATC
ACTCAAGTGTCAACACTAATTGCAGTAACGTTTCAGAATTACCTGAATTAACTTTCGTCA
TCGATGGTGCCCACTATACATTAACAGGAGAAGAATATGTTTTATAAGAAAACTCTGATG
GTTCTCAATAGACTGTTGAAACTGCTTAATCTAATGTTGAAATGAGCAGCTCCACTGCAT
AATGTATTGTTGCTTTCATGCCTCTTGATATTCCCAATGATGAAGAAAATTTCCCTTATG
AAAAAGCTTGGATTTTGGTAATAAATTTTTTTCAAAGAAATAATTTGATATTAAAATATT
GATTTTAAAATAAAATAGGGAGATACTTTCTTACAAAAGTTTTATTCAATTTATGATAGA
GACAATGACAGAGTTGGTTTTGCTTTGGCAAGACATTGA

>TTHERM_00321680(protein)
MRRSLLTVALFAVCLLSFAMAVHIRKDKQQTLESKAKLYSAEGDELHTISLKKIPQSPGE
RRKAIELLSTAQYYSYNKDDYSAEKDFIYTQQKETSFTSTSSNSKTSTHTVKLYNFKNVQ
YTGDLAIGSSDNVFSVIYDTGSANIWMNSIHCNDPGCVSHKQYDFHQSKNYKSVGLSLDV
QFGTGELIGEMAQDTVYFGDIEIKDQTFVEIHEQRGDVFAQSKFDGIVGLAFPSMAAYNK
NPLFDSLIEQKKIQKNIFSFYMSPHDGRTDSEISIGGANPLRYSGEIKYHKVKKDYYWLI
EAQSILVGGKDVGLCKGGCYVIADTGTSLITGPSEDIFTLLDHSSVNTNCSNVSELPELT
FVIDGAHYTLTGEEYVLQENSDGSQQTVETAQSNVEMSSSTAQCIVAFMPLDIPNDEENF
PYEKAWILGDTFLQKFYSIYDRDNDRVGFALARH