Identifiers and Description

Gene Model Identifier

TTHERM_00327110

Standard Name

TTLL6F

Aliases

PreTt30214 | 33.m00226 | 3705.m00054

Description

TTLL6F tubulin-tyrosine ligase family protein; Tubulin-tyrosine ligase family protein, Beta-tubulin polyglutamylase; Tubulin-tyrosine ligase/Tubulin polyglutamylase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity (IEA) | GO:0008413
• acid-amino acid ligase activity (ISS) | GO:0016881
• axon guidance receptor activity (IEA) | GO:0008046
• glucan 1,4-alpha-maltotetraohydrolase activity (IEA) | GO:0033910
• L-ribulose-5-phosphate 3-epimerase activity (IEA) | GO:0034015
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• phosphatidylserine decarboxylase activity (IEA) | GO:0004609
• R-linalool synthase activity (IEA) | GO:0034008
• sphingomyelin phosphodiesterase activity (IEA) | GO:0004767
• titin binding (IEA) | GO:0031432

Biological Process

• 3-keto-sphinganine metabolic process (IEA) | GO:0006666
• cell wall modification involved in fruit ripening (IEA) | GO:0009829
• negative regulation of complement-dependent cytotoxicity (IEA) | GO:1903660
• negative regulation of epithelial cell-cell adhesion involved in epithelium migration (IEA) | GO:1903682
• negative regulation of fractalkine production (IEA) | GO:0032684
• negative regulation of hepatocyte growth factor production (IEA) | GO:0032686
• neutral lipid metabolic process (IEA) | GO:0006638
• photosynthesis, light harvesting in photosystem I (IEA) | GO:0009768
• plant-type cell wall modification (IEA) | GO:0009827
• positive regulation of peroxisome proliferator activated receptor signaling pathway (IEA) | GO:0035360
• positive regulation of response to water deprivation (IEA) | GO:1902584
• positive regulation of wound healing, spreading of epidermal cells (IEA) | GO:1903691
• priming of cellular response to stress (IEA) | GO:0080136
• protein polyglutamylation (ISS) | GO:0018095
• regulation of complement-dependent cytotoxicity (IEA) | GO:1903659
• regulation of L-arginine import into cell (IEA) | GO:1902826
• regulation of TRAIL production (IEA) | GO:0032679

Domains

• ( PF03133 ) Tubulin-tyrosine ligase family

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:15890843: Janke C, Rogowski K, Wloga D, Regnard C, Kajava AV, Strub JM, Temurak N, van Dijk J, Boucher D, van Dorsselaer A, Suryavanshi S, Gaertig J, Eddé B (2005) Tubulin polyglutamylase enzymes are members of the TTL domain protein family. Science (New York, N.Y.) 308(5729):1758-62

Sequences

>TTHERM_00327110(coding)
ATGTCTTAGAGCGATTTTAAAGAGGAGTAATTAGACTCTAAAAAGAGCAGTAAGCAAGTT
GCTGATAAAAAGGAATTGGTTTTAGGTATCAATTTTGATCCTGATAAAGAGGAATACGAT
GGAAACTACTCTGATTCTGGAGAAGAATCCGAATCAGAATAAGCATAAACAAATTATGAC
GATGATATGGCAGAAGATGAGTAACTAGTGCCAGAAGATGGTGTTTCAACAAAATAAAAT
AATAATAAAAAAGGAAACGGTGATAAAAAAACTAAGAAAGTAAAAAAAGCTCCTGCAAAA
TAGGCATCTTAGGCTAAAAGAAAGCCACAAACTTTGGTTATGAATGTTGCTGATACATAG
TATCCTGTTGTTAAATTCGTGGGCAAAAAGATTTTCAAATGGAAACTTTGTTATGATGCA
GAAAACACTGATTGCGATATTACTTGGACTGATAACGCTGTTTAACCAGAATAGCTAGGA
AAAATGCAGCCCCATTAAAAAATTAATCACTTTCCTGGCATGTTTGTGCTAGCTAGAAAA
AACCACTTAGCTAGAAATCTAAAAAAAATGAAGAAACAGTTCCCTGATCACTATAAATTT
TTCCCTTAAACTTGGTTATTGCCTGCTGAATACAACGAACTTCGTACTGAATTCGATAAG
ATCTCTAAAGGAAAATGCAAAACATTTATTGTTAAACCAGAAGCAAGTTGCTAGGGAAGA
GGTATCTTTTTGACTAGGAATTTAGATGATTTAAACAGTACCGATCATTATGTAGTTTAA
AGATATTTACACAAGCCCTATCTCATAGATGGATTAAAGTTTGATTTTAGAATTTACGTT
TTGCTTGCAGCTTGTGATCCTATGAGAATATATATTTTTAAAGAAGGATTAGCTCGTTTA
GCTACAGAAGAATATGAAGCTCCACATCGTGATAATTTAGATAATCTTTGCATGCACTTA
ACTAACTATGCCATCAATAAAGATAACCCTAATTTTGAATTTAATGAAGATGAAAATTAA
ATGGATGTAGGTCACAAAAGGTCTTTGACTTCAGTAATGGAGCTTCTTAAAAATTAAGGA
CATGATATTTAAAAGTTATGGGATCAAATTAAGGACATCATAATAAAAACAATAATTAGT
GCTTAGCCTACTCTAAGTCATCACTATAAATCTTGTCAACCAGATAACTACATGAATAAT
ATGTGTTTTGAAATATTGGGATTTGATGTTTTCTTAGACGCCCATTTAAAACCTTGGCTA
TTAGAAATTAATCATACTCCTAGTTTTACTACAGATACTCCTCTTGATAGTTTGATCAAA
AAGAATTGTATCCGTGATGCATTAACATTGATGAATTCGACTGTTAAAGCTAGAAACGAA
ATTGTTTCACAAAGAAAGGAATAACTTTAAAAAAGAGTCCTAACTGGTAAAAAATAAAAA
TTAACAGCTGAAGAAAAAGCAGCTGAAATAAAAAAAGCTATGTAAAAGAGGGATGAGTAC
GAATCAAAGAATTTAGGAAACTATGAAAAGGTTTATCCTCTAGAACCTGATGTTGAAGAT
ATTTACATTGCTTTCCAACAACACTCTCAATAGCTTTATGAAAACTGGACGGGAGCAAAT
ATTAGAAGAGTCTCAAAGAAAGACAGTTCAATAGGAGGTAATACTATCTAAGGAACAACA
GCGAATAACAGTGTCAAAGGAGTACCAAATTAACAAAGAAATTCGATAAATGATAAAAAT
AAACCAAACTTACCTGCAGCTAAGGTACCAATTAAGCCAGTTGCAGCCACCAAATAAGTG
ATTCCTAAAGTTGTCTAAAATAAGACTCAAGTTCCCACCTTCTCTTCAAGCTCGAAAATT
AGATCAAATGAAAATATTGAAGGAGAAGATGGATAATTTAAACTCCCTAAATAAATAAAA
TTATAGAGCCAGCAGACATCCAGCAACTTGAGTGCTAGCCAAACAGGTGGCTACTCTGAG
ACTTACTAAATTAATGAAACACCTGGAAAGTTTTCTGATAATAATAGTGGAGTGTATTAG
AAACCTCCCAGCCCATTTACTTTGGGAAGTACCGGTTAAATCAGTAGCTTAGATGCAAGA
AAATAGTACGCTATTCCAAAATAAATAGGCTCATCTCTATAAAACGAAGAAGAAAGACAG
TAAATGGTAAAAAAATATGCATAGTTTGCAATAGATCTTAATTCCTAATCAAGTAATACT
AGCAGCTCTTTGAATAATGTCTAAATTTAAAAGAAATAATACGAAAACACTAATTAACTA
ACCTAACAATACAATACCGATATAAATGCTTAACAATCTCCATATCAGTATATCAGATAA
CAAAGCCAGCAGAGCTCAATTTAACCTCCTCAGAATTTAAATAGCACTGGTAGACCCTAA
TTTCAATAAATTAATATGCAGTAATACCCAGTTAAAATGCTTCCTGGACTTGTAAGAAAC
GGTATGAATAACGATGACTATGTAGCATTGACTCATCAAAAAAGAATGTAAGAAATGAAT
AAGTACTCTAAACCATTATAAACTTCAAATAACAATGGACTTTATTTGTAGCCAAAGCTA
TTTGATCTAAATGTATTAACCAAAATGAATGATGAAGAACCTATAAGAAAAGATTAAATA
GTTAGAAATAAGTAAGTGGTATACTCAAATATCTCCTCAAATAACTTTGGTAATAACTAT
GATATAAATTCATAAAAGCTAATAACTAATAATAATTACTATACAAGAAGAAAATGA

>TTHERM_00327110(gene)
AAAAAGAGTTTCTTATTTCAAACAAATTCATTGATTGATTAACTCAGTTTATAATCAAGT
CTATTTCAATTGTATAGCTAATTTATATTTTTTTATATTTTAAATAGTAAATCCAGTCTG
AATTATCAAACGGAGTCAATCAACCATACAAGAGTGATTGATAAAATTCATATAGAAAAC
AACTAACTAACAAACTAACAATCATAATAAGCTCATAAATAAAGAAACAAGCAAATATTC
ATAAAAAATTAAATAAATAATCATCAAACTTAATGTCTTAGAGCGATTTTAAAGAGGAGT
AATTAGACTCTAAAAAGAGCAGTAAGCAAGTTGCTGATAAAAAGGAATTGGTTTTAGGTA
TCAATTTTGATCCTGATAAAGAGGAATACGATGGAAACTACTCTGATTCTGGAGAAGAAT
CCGAATCAGAATAAGCATAAACAAATTATGACGATGATATGGCAGAAGATGAGTAACTAG
TGCCAGAAGATGGTGTTTCAACAAAATAAAATAATAATAAAAAAGGAAACGGTGATAAAA
AAACTAAGAAAGTAAAAAAAGCTCCTGCAAAATAGGCATCTTAGGCTAAAAGAAAGCCAC
AAACTTTGGTTATGAATGTTGCTGATACATAGTATCCTGTTGTTAAATTCGTGGGCAAAA
AGATTTTCAAATGGAAACTTTGTTATGATGCAGAAAACACTGATTGCGATATTACTTGGA
CTGATAACGCTGTTTAACCAGAATAGCTAGGAAAAATGCAGCCCCATTAAAAAATTAATC
ACTTTCCTGGCATGTTTGTGCTAGCTAGAAAAAACCACTTAGCTAGAAATCTAAAAAAAA
TGAAGAAACAGTTCCCTGATCACTATAAATTTTTCCCTTAAACTTGGTTATTGCCTGCTG
AATACAACGAACTTCGTACTGAATTCGATAAGATCTCTAAAGGAAAATGCAAAACATTTA
TTGTTAAACCAGAAGCAAGTTGCTAGGGAAGAGGTATCTTTTTGACTAGGAATTTAGATG
ATTTAAACAGTACCGATCATTATGTAGTTTAAAGATATTTACACAAGCCCTATCTCATAG
ATGGATTAAAGTTTGATTTTAGAATTTACGTTTTGCTTGCAGCTTGTGATCCTATGAGAA
TATATATTTTTAAAGAAGGATTAGCTCGTTTAGCTACAGAAGAATATGAAGCTCCACATC
GTGATAATTTAGATAATCTTTGCATGCACTTAACTAACTATGCCATCAATAAAGATAACC
CTAATTTTGAATTTAATGAAGATGAAAATTAAATGGATGTAGGTCACAAAAGGTCTTTGA
CTTCAGTAATGGAGCTTCTTAAAAATTAAGGACATGATATTTAAAAGTTATGGGATCAAA
TTAAGGACATCATAATAAAAACAATAATTAGTGCTTAGCCTACTCTAAGTCATCACTATA
AATCTTGTCAACCAGATAACTACATGAATAATATGTGTTTTGAAATATTGGGATTTGATG
TTTTCTTAGACGCCCATTTAAAACCTTGGCTATTAGAAATTAATCATACTCCTAGTTTTA
CTACAGATACTCCTCTTGATAGTTTGATCAAAAAGAATTGTATCCGTGATGCATTAACAT
TGATGAATTCGACTGTTAAAGCTAGAAACGAAATTGTTTCACAAAGAAAGGAATAACTTT
AAAAAAGAGTCCTAACTGGTAAAAAATAAAAATTAACAGCTGAAGAAAAAGCAGCTGAAA
TAAAAAAAGCTATGTAAAAGAGGGATGAGTACGAATCAAAGAATTTAGGAAACTATGAAA
AGGTTTATCCTCTAGAACCTGATGTTGAAGATATTTACATTGCTTTCCAACAACACTCTC
AATAGCTTTATGAAAACTGGACGGGAGCAAATATTAGAAGAGTCTCAAAGAAAGACAGTT
CAATAGGAGGTAATACTATCTAAGGAACAACAGCGAATAACAGTGTCAAAGGAGTACCAA
ATTAACAAAGAAATTCGATAAATGATAAAAATAAACCAAACTTACCTGCAGCTAAGGTAC
CAATTAAGCCAGTTGCAGCCACCAAATAAGTGATTCCTAAAGTTGTCTAAAATAAGACTC
AAGTTCCCACCTTCTCTTCAAGCTCGAAAATTAGATCAAATGAAAATATTGAAGGAGAAG
ATGGATAATTTAAACTCCCTAAATAAATAAAATTATAGAGCCAGCAGACATCCAGCAACT
TGAGTGCTAGCCAAACAGGTGGCTACTCTGAGACTTACTAAATTAATGAAACACCTGGAA
AGTTTTCTGATAATAATAGTGGAGTGTATTAGAAACCTCCCAGCCCATTTACTTTGGGAA
GTACCGGTTAAATCAGTAGCTTAGATGCAAGAAAATAGTACGCTATTCCAAAATAAATAG
GCTCATCTCTATAAAACGAAGAAGAAAGACAGTAAATGGTAAAAAAATATGCATAGTTTG
CAATAGATCTTAATTCCTAATCAAGTAATACTAGCAGCTCTTTGAATAATGTCTAAATTT
AAAAGAAATAATACGAAAACACTAATTAACTAACCTAACAATACAATACCGATATAAATG
CTTAACAATCTCCATATCAGTATATCAGATAACAAAGCCAGCAGAGCTCAATTTAACCTC
CTCAGAATTTAAATAGCACTGGTAGACCCTAATTTCAATAAATTAATATGCAGTAATACC
CAGTTAAAATGCTTCCTGGACTTGTAAGAAACGGTATGAATAACGATGACTATGTAGCAT
TGACTCATCAAAAAAGAATGTAAGAAATGAATAAGTACTCTAAACCATTATAAACTTCAA
ATAACAATGGACTTTATTTGTAGCCAAAGCTATTTGATCTAAATGTATTAACCAAAATGA
ATGATGAAGAACCTATAAGAAAAGATTAAATAGTTAGAAATAAGTAAGTGGTATACTCAA
ATATCTCCTCAAATAACTTTGGTAATAACTATGATATAAATTCATAAAAGCTAATAACTA
ATAATAATTACTATACAAGAAGAAAATGAAAATTAATTTATATTGCAACCATAAAAAAAA
TAAATTAATAAACATCTAATATCCACAACAATAAAAAGAAAGTGAACATTTTTCTTATTT
TAAATATGGGGCAATTTATAATAGCTTTACATGATGCAGCCATTTAAAAAAGAAAAACTT
TTATTTTGTTGAATGTTATCGAAATAACTAACCAATTAATTATCTATCTAACTAAATAAC
TTATAACAATAAATAAATAAATAAATTTATTTTAAAAAACATTTAAAATAAACAAATAAA
TTAATTATAATTATATTTTAAATTTAATTTAAACTTATCAATATAATAATATTAATATAT
TTTATACTCTCAATTTGATCCATTTGTTTGTTCTTCTTTTATTCATT

>TTHERM_00327110(protein)
MSQSDFKEEQLDSKKSSKQVADKKELVLGINFDPDKEEYDGNYSDSGEESESEQAQTNYD
DDMAEDEQLVPEDGVSTKQNNNKKGNGDKKTKKVKKAPAKQASQAKRKPQTLVMNVADTQ
YPVVKFVGKKIFKWKLCYDAENTDCDITWTDNAVQPEQLGKMQPHQKINHFPGMFVLARK
NHLARNLKKMKKQFPDHYKFFPQTWLLPAEYNELRTEFDKISKGKCKTFIVKPEASCQGR
GIFLTRNLDDLNSTDHYVVQRYLHKPYLIDGLKFDFRIYVLLAACDPMRIYIFKEGLARL
ATEEYEAPHRDNLDNLCMHLTNYAINKDNPNFEFNEDENQMDVGHKRSLTSVMELLKNQG
HDIQKLWDQIKDIIIKTIISAQPTLSHHYKSCQPDNYMNNMCFEILGFDVFLDAHLKPWL
LEINHTPSFTTDTPLDSLIKKNCIRDALTLMNSTVKARNEIVSQRKEQLQKRVLTGKKQK
LTAEEKAAEIKKAMQKRDEYESKNLGNYEKVYPLEPDVEDIYIAFQQHSQQLYENWTGAN
IRRVSKKDSSIGGNTIQGTTANNSVKGVPNQQRNSINDKNKPNLPAAKVPIKPVAATKQV
IPKVVQNKTQVPTFSSSSKIRSNENIEGEDGQFKLPKQIKLQSQQTSSNLSASQTGGYSE
TYQINETPGKFSDNNSGVYQKPPSPFTLGSTGQISSLDARKQYAIPKQIGSSLQNEEERQ
QMVKKYAQFAIDLNSQSSNTSSSLNNVQIQKKQYENTNQLTQQYNTDINAQQSPYQYIRQ
QSQQSSIQPPQNLNSTGRPQFQQINMQQYPVKMLPGLVRNGMNNDDYVALTHQKRMQEMN
KYSKPLQTSNNNGLYLQPKLFDLNVLTKMNDEEPIRKDQIVRNKQVVYSNISSNNFGNNY
DINSQKLITNNNYYTRRK