Identifiers and Description

Gene Model Identifier

TTHERM_00334520

Standard Name

RAB5B

Aliases

PreTt05997 | 34.m00234 | 3689.m00032

Description

RAB5B small guanosine triphosphatase family Ras family protein; Rab V family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• intracellular anatomical structure (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase-mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00009 ) Elongation factor Tu GTP binding domain
• ( PF00025 ) ADP-ribosylation factor family
• ( PF00071 ) Ras family
• ( PF01926 ) 50S ribosome-binding GTPase
• ( PF08477 ) Ras of Complex, Roc, domain of DAPkinase
• ( TIGR00231 ) small GTP-binding protein domain
• ( TIGR00650 ) GTP-binding conserved hypothetical protein

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_16044.1	6.001241942754875e-123
	Description: small GTP-binding protein domain-containing protein (205 aa)
WormBase	WBGene00002215	6.001241942754875e-123
	Description: locus:klc-2 Kinesin light chain status:Confirmed UniProt:P46822 protein_id:CCD65113.1
Oxytricha	Contig22448.0.g39	4.998711177326993e-55
	Description: Ras family
WormBase	WBGene00004268	2.998863950472602e-38
	Description: locus:rab-5 status:Partially_confirmed UniProt:P91857 protein_id:CAB04205.1
SGD	YOR089C	2.998863950472602e-38
	Description: VPS21 Rab family GTPase required for endocytic transport and for sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog
Tetrahymena borealis	EI9_09874.1	2.998863950472602e-38
	Description: hypothetical protein (484 aa)
DictyBase	DDB_G0289827	3.0001084582952455e-37
	Description: rab18 on chromosome: 5 position 3292859 to 3293559
Stentor Coeruleus	SteCoe_28677	1.0530617357553812e-20
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00334520(coding)
ATGAGTAAAAAATAGAATAAAGATAGTGGAGGTGGTTGCTGTGGCGGCAGTAGCAGCTCA
AACAATTCAGTATAAAAGCCATTAAATACAAAAAAAAAAGAAATTAAGGTAGTATTATTA
GGTGACCCTAATGTAGGAAAAAGTTCTATTGCGTTGAGATATTGCAAGCATTAATTTAGT
GAAACATATGAGCTCACAATAGGAGGTGTTTATAATTTAAAAGAGACTACATTATCTAAC
GGATAAAAAGTTGCAATTCACCTTTGGGATACTGGTGGTGAAGAAAAATTTAGATCAATG
ACCCAGTTATATTATAATGACGCTTAAGCAGCTATTTTAGTTTATGATGTCTAAAATGCA
TAAACATTTTAAAGTTTAGAGTATTGGTTAAAAGAATTAGAAAATAAAGTTTCTAATTAA
GGAATGATATTGTGTATAGCTGGAAATAAATGTGATGTGGATGAAGATTTGAGAGCTGTA
ACCTACGATTAAGGAGCTTAATTTTGTAAAAATAATAATAATATAATATTTGCTGAAACA
TCAGCAAAAACAAATTAAGGAATTGATGACCTCTTTAATGAATTGTTAGAAAAGATATAA
AATAAACTATGA

>TTHERM_00334520(gene)
ATGAGTAAAAAATAGAATAAAGATAGTGGAGGTGGTTGCTGTGGCGGCAGTAGCAGCTCA
AACAATTCAGTATAAAAGCCATTAAATACAAAAAAAAAAGAAATTAAGGTAGTATTATTA
GGTGACCCTAATGTAGGAAAAAGTTCTATTGCGTTGAGATATTGCAAGCATTAATTTAGT
GAAACATATGAGCTCACAATAGGAGGTGTTTATAATTTAAAAGAGACTACATTATCTAAC
GGATAAAAAGTTGCAATTCACCTTTGGGATACTGGTGGTGAAGAAAAATTTAGGTAAAAT
TTATTTTGCTTTCCAAATTATTAATAACAAACAGACACACACAGTAAAATGAAATAACAG
AATAAAATGTTATATTGCTGAAAATTTATTACAAATTTAATTTAAGAAAGTAAAAAATAT
AAAATAAATTTAAATAGATCAATGACCCAGTTATATTATAATGACGCTTAAGCAGCTATT
TTAGTTTATGATGTCTAAAATGCATAAACATTTTAAAGTTTAGAGTATTGGTTAAAAGAA
TTAGAAAATAAAGTTTCTAATTAAGGAATGATATTGTGTATAGCTGGAAATAAATGTGAT
GTGGATGAAGATTTGAGAGCTGTAACCTACGATTAAGGAGCTTAATTTTGTAAAAATAAT
AATAATATAATATTTGCTGAAACATCAGCAAAAACAAATTAAGGAATTGATGACCTCTTT
AATGAATTGTTAGAAAAGATATAAAATAAACTATGA

>TTHERM_00334520(protein)
MSKKQNKDSGGGCCGGSSSSNNSVQKPLNTKKKEIKVVLLGDPNVGKSSIALRYCKHQFS
ETYELTIGGVYNLKETTLSNGQKVAIHLWDTGGEEKFRSMTQLYYNDAQAAILVYDVQNA
QTFQSLEYWLKELENKVSNQGMILCIAGNKCDVDEDLRAVTYDQGAQFCKNNNNIIFAET
SAKTNQGIDDLFNELLEKIQNKL