Identifiers and Description

Gene Model Identifier

TTHERM_00335720

Standard Name

DDI1 (DNA Damage Inducible 1)

Aliases

PreTt06017 | 34.m00254 | 3689.m00051

Description

DDI1 DNA damage-inducible protein putative; UBA/TS-N domain containing protein; involved in the ubiquitin proteasome system; homolog of Homo sapiens DDI1

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• aspartic-type endopeptidase activity (IEA) | GO:0004190

Biological Process

• proteolysis (IEA) | GO:0006508

Domains

• ( PF00077 ) Retroviral aspartyl protease
• ( PF00240 ) Ubiquitin family
• ( PF00627 ) UBA/TS-N domain
• ( PF08284 ) Retroviral aspartyl protease
• ( TIGR02281 ) clan AA aspartic protease, TIGR02281

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_16073.1	9.997093137033517e-262
	Description: UBA/TS-N domain-containing protein (434 aa)
WormBase	WBGene00010138	9.997093137033517e-262
	Description: locus:anoh-1 Anoctamin status:Partially_confirmed UniProt:G5EBW3 protein_id:CAX51677.2
Oxytricha	Contig11687.0.g111	5.997672135862771e-69
	Description: Aspartyl protease
SGD	YER143W	2.000065869309806e-55
	Description: DDI1 DNA damage-inducible v-SNARE binding protein with a role in suppression of protein secretion; may play a role in S-phase checkpoint control; has ubiquitin-associated (UBA), ubiquitin-like (UBL), and retroviral-like proteinase (RVP) domains
DictyBase	DDB_G0288187	1.999385218781115e-51
	Description: ddi1 on chromosome: 5 position 1180046 to 1181767
WormBase	WBGene00015308	2.0006622580855403e-35
	Description: status:Confirmed UniProt:Q17569 protein_id:CCD62447.1

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00335720(coding)
ATGAAAATAACAATTATAACTGAGGACGATTAATTTAAGGAAATCGAATTTGAAGCCGAC
TCAAGAGTTATAGATATTAAAGAAGTGTTATAAATTGAGTTTGGAATTCCAGTTGCAATT
CAGGAATTGTTTGCTAATAATTAGCTTATGAATAATAATAATTTGATTAGAGAATATTGT
GGCGACAACGATATGATTAGATTAAGCACCAAACAAAACTAATTTGGTAGATAATAATAG
ATGATGGGATTTAACAACAATTAAATAAACAATCAATAGTTCACAAATAATGCAACAAAT
ATTGCAAATGCTCTATCAAATTTATTTGGCAGCACACTTAATCAATCTATTCACTAAAAA
TATTTATAATAAGCTAGAGATTTTAAGAATTAAATTAAGCAATAGCCTTTTATTTTACAG
AATTTAAAAAATTAAAATCCTAAACTAGCACAGCTTCTTCAAAGCGGAACTGATGATGAA
TTGGCTTAATTTTTGTAAAAAACTGAGCAAGAAAGAATTCAAAAGAGAATGAAAGAATAG
TAGGAACTTGATGAGCTTGAAAAAGATCCTTTCAACCCTGATAATTAAAAGAAGATAGAA
GAAATTATCAACTAAAGAGTTATTGATGAAAATTTAGAAATGGCTTAGGAATATATTCCT
GAAGTTTTTGGAAAAATTACAATGCTTTATATTGATTGTGTAATTAATGATCATCCAATC
TAGGCCTTCGTTGATACAGGTGCTGAAAGTACTATTATGTCAAAAGCATGTGCAGAGAGA
TGTGGACTTATGAGATTAGTTGATAAAAGATTTTCTGGTATGGCAAGTGGTGTTGGAACT
GGAAAAATTCTTGGCCGTATTCATAAATACGCAATTTAGATATTAGATAAAAGATTTGAA
TGTTCTTTCACTATCCTTGAATCGATTAATTTAGATTTCCTTTTAGGTTTAGATAATTTA
AGAAGATTTTAATGCAATGTTAATTTAAGAGATAACACTCTTAATTTTTGGCTAGGAGAC
TCAGAACTTAAAGTCCCTTTCTTACATGAAAAAGATATTAAAAAAGTAGTTTCTATTGAA
TAAGAATAAGCCTTATTTGATGAAGAATAAAAAAGAAATCAAGAGTAGCCTCCTTTAAGT
ATGTAAAGATAGTCTAGTAGCTCATCGTAAATTATTGGTGGTACTGTAGGATTTAGAGAG
GATGACATAGGAAAATTAATCAACTTAGGAGCAACAAGAGAACAAGCAATAAATGCTTTA
AAGGCTGCAGGAGGTAACGTTGAGCTAGCAGCTAGTATTCTGACAATGAAATTTTGA

>TTHERM_00335720(gene)
ATGAAAATAACAATTATAACTGAGGACGATTAATTTAAGGAAATCGAATTTGAAGCCGAC
TCAAGAGTTATAGATATTAAAGAAGTGTTATAAATTGAGGTATTAAATTAGAATTGATAG
TATTTTAATTTAATATTCTAATTTTTTGATGGTGTAATAATAAAAAAGTTTGGAATTCCA
GTTGCAATTCAGGAATTGTTTGCTAATAATTAGCTTATGAATAATAATAATTTGATTAGA
GAATATTGTGGCGACAACGATATGATTAGATTAAGCACCAAACAAAAGTACTCAGTTATT
CATAAAGTCAATATTAACATTTTTTTAACTTTAAAATAGCTAATTTGGTAGATAATAATA
GATGATGGGATTTAACAACAATTAAATAAACAATCAATAGTTCACAAATAATGCAACAAA
TATTGCAAATGCTCTATCAAATTTATTTGGCAGCACACTTAATCAATCTATTCACTAAAA
ATATTTATAATAAGCTAGAGATTTTAAGAATTAAATTAAGCAATAGCCTTTTATTTTACA
GAATTTAAAAAATTAAAATCCTAAACTAGCACAGCTTCTTCAAAGCGGAACTGATGATGA
ATTGGCTTAATTTTTGTAAAAAACTGTAAAATATTTTATAATAAAATACATAAAATTGAA
TATTTAAATATTTATATCAAGGAGCAAGAAAGAATTCAAAAGAGAATGAAAGAATAGTAG
GAACTTGTAAGATTCTATAATTAATCAAAACCTTCATATTTAAATATAAATTATATATCA
ATAAATAGGATGAGCTTGAAAAAGATCCTTTCAACCCTGATAATTAAAAGAAGATAGAAG
AAATTATCAACTAAAGAGTTATTGATGAAAATTTGTATTATTTATTTTATTTGTTTAGAT
TTTAATTTGATATAATTATTTAAATAGAGAAATGGCTTAGGAATATATTCCTGAAGTTTT
TGGAAAAATTACAATGCTTTATATTGATTGTGTAATTAATGATCATCCAATCTAGGCCTT
CGTTGATACAGGTGCTGAAAGTACTATTATGTCAAAAGCATGTGCAGAGAGATGTGGGTA
TTCAATAATTTTTATTTAACCAAAGGTTATAATAATAAATAATAAAAAGACTTATGAGAT
TAGTTGATAAAAGATTTTCTGGTATGGCAAGTGGTGTTGGAACTGGAAAAATTCTTGGCC
GTATTCATAAATACGCAATTTAGATATTAGATAAAGTAATAAAAAATATAATCCAAAGAA
GTCATATAAAATTTTTAATCAAAATAAATAGAGATTTGAATGTTCTTTCACTATCCTTGA
ATCGATTAATTTAGATTTCCTTTTAGGTTTAGATAATTTAAGAAGATTTTAAGTATTTTT
TTAAATGTATATTTCATTAACTCATTTTAATTATTTTGTGAATAGTGCAATGTTAATTTA
AGAGATAACACTCTTAATTTTTGGCTAGGAGACTCAGAACTTAAAGTCCCTTTCTTACAT
GAAAAAGATATTAAAAAAGTAGTTTCTATTGAATAAGAATAAGCCTTATTTGATGAAGAA
TAAAAAAGAAATCAAGAGTAGCCTCCTTTAAGTATGTAAAGATAGTCTAGTAGCTCATCG
TAAATTATTGGTGGTACTGTAGGATTTAGAGAGGATGACATAGGAAAATTAATCAACTTA
GGAGCAACAAGAGAACAAGCAATAAATGCTTTAAAGGCTGCAGGAGGTAACGTTGAGCTA
GCAGCTAGTATTCTGACAATGAAATTTTGA

>TTHERM_00335720(protein)
MKITIITEDDQFKEIEFEADSRVIDIKEVLQIEFGIPVAIQELFANNQLMNNNNLIREYC
GDNDMIRLSTKQNQFGRQQQMMGFNNNQINNQQFTNNATNIANALSNLFGSTLNQSIHQK
YLQQARDFKNQIKQQPFILQNLKNQNPKLAQLLQSGTDDELAQFLQKTEQERIQKRMKEQ
QELDELEKDPFNPDNQKKIEEIINQRVIDENLEMAQEYIPEVFGKITMLYIDCVINDHPI
QAFVDTGAESTIMSKACAERCGLMRLVDKRFSGMASGVGTGKILGRIHKYAIQILDKRFE
CSFTILESINLDFLLGLDNLRRFQCNVNLRDNTLNFWLGDSELKVPFLHEKDIKKVVSIE
QEQALFDEEQKRNQEQPPLSMQRQSSSSSQIIGGTVGFREDDIGKLINLGATREQAINAL
KAAGGNVELAASILTMKF