Identifiers and Description

Gene Model Identifier

TTHERM_00348000

Standard Name

TTLL15B

Aliases

PreTt05212 | 36.m00176 | 3703.m00009

Description

TTLL15B tubulin tyrosine ligase family protein; Similar to tubulin polyglutamylase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• acid-amino acid ligase activity (ISS) | GO:0016881

Biological Process

• protein polyglutamylation (ISS) | GO:0018095

Domains

• ( PF00533 ) BRCA1 C Terminus (BRCT) domain
• ( PF03133 ) Tubulin-tyrosine ligase family
• ( PF04326 ) Schlafen, AlbA_2
• ( PF08814 ) XisH protein

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_09721.1	9.997093137033517e-262
	Description: hypothetical protein (1612 aa)
WormBase	WBGene00012929	9.997093137033517e-262
	Description: locus:rsks-1 Ribosomal protein S6 kinase status:Partially_confirmed UniProt:Q9NAH6 protein_id:CAB55075.2
Stentor Coeruleus	SteCoe_2072	1.5628821893349888e-18
	Description: None
Oxytricha	Contig19772.0.0.g73	0.0000000000000700196834671948
	Description: Tubulin-tyrosine ligase family
WormBase	WBGene00044187	0.0000000010002658722841845
	Description: locus:ttll-9 status:Partially_confirmed UniProt:Q564U4 protein_id:CAI79169.1
WormBase	WBGene00001137	0.0000000010002658722841845
	Description: locus:eat-6 status:Confirmed UniProt:P90735 protein_id:CAB02694.1
DictyBase	DDB_G0281541	0.000006997203421143941
	Description: DDB_G0281541 on chromosome: 3 position 4627625 to 4629265

General Information

No Data fetched for General Information

Associated Literature

1. Ref:15890843: Janke C, Rogowski K, Wloga D, Regnard C, Kajava AV, Strub JM, Temurak N, van Dijk J, Boucher D, van Dorsselaer A, Suryavanshi S, Gaertig J, Eddé B (2005) Tubulin polyglutamylase enzymes are members of the TTL domain protein family. Science (New York, N.Y.) 308(5729):1758-62

Sequences

>TTHERM_00348000(coding)
ATGAAAAAAAAGACTTAAAAAAAAGTAGAATAAACAAAAAGCTTAGTAGACAGGTTGAGG
TCAATTTAACTATGGCAAATTATACTAGGTATAATTGTCATATTATTGGCCAGAAATTTT
TATTTAAACAACGATTTGCATCCATAGCAGCAGAATTCAAATGAGTTTTCTTAAGATGAT
TATTATGTAGAAAATATGCATGGGGAAGCAAATTATATGCTTAAAGATAATCTCAAAAAA
TTGGCACACCCTGATGTTGGAAAATATAAAAAGAGAGTTTCTTAACCTTTGGATTAATTT
TGGTAAGGAAAGGAAAAAATAGCAGAAAGAATTGCTTCTCTCTTTAACGAATTTAATTAT
AAATAAATGGATTTGCAAATACATTTTGAAAATAGCAGAAACTATGATAGGCCCTCTTTA
GGTATAATCAGTGATCCTGAGTATTGTAAAAAAAGTAATATGCATCATATTTTGCATCCT
GAGTCAATTTAAAAAAACTATTTGATATTTACAGATTTTGGATATAATGAATTGCCAAGA
GAGGTTGCTTAGCAATTTGGTGTTGACTTACTTCCTTAAGTTTCTTAGTAAATGAGTGAT
AGAAAATAATAAGAAAGAGTATATAATCTACCAGTCGAAACTGCTTTGATTCACTCTAGA
ATATCTAGAATACACCATTTTTTTGAGTTTAATAAGAATATTATTTGCACATATTAATCA
GCAAATCATATTCCAGGTAAATGGTCTATCACTGGAAAAGATTTAGTCATAGATAATTAC
AGACTTTACTAGTAAAAACCATTTATTAACAAGGATAAATGCTGGTAGCATGTTACATTT
ATGCCAGAGTCTTATCGTTTATACAATTCAAACGAATGCAAGAGTTTTTTCAAATTTCTT
TAATCAGATGAATACAAGGAATTAATCAAAAAAGATGGAATAGGATTTATAATGAAGTAG
GGAAGAGATATTCATCGTGGTTAAGGAATTAATTTAATTTCTCCTTAAATTTTGTAAGAT
TTGATGAAGAAATACAATAACGGAAACAAGTGTGACTCTATTCATGAAGTTTATCAAGTT
CAAAGGTACGTTAATAATCCTATATTGCATGATAACAAGAAGTTGGAAGTTCGTATTTAC
TTTTTTATTGCAAGTACTGATCCTTTGATAATCTATGTTTAGAAATTAGCCCTTCTTAAA
AAATGTGCCAGCGATTATAATAAATTCGATTATGATTTTTCTAGACATGTTTGCAATACC
TCAATTAGTAAATAAATAACTGACTCATTCGTAGTTGAATTTGCTCTAGAAGGTTTAGAA
AAGTACTTACTAGAAAACAATAAAATCACTAACCCTAAGTGGCTAGAAGAAGAAATTTAT
CCATAAATTTACAGAGCAGTCACACATTTGGTAAGATCTGGAGCTCATGATTTTTTGATT
GACTCTCGTGTGAATGAAAACTTTGCTTTAGACTTTTTGATAGATGAAGATTCAAAAGTA
TGGTTCTTAGAAAATAATCCTAATCCTCAAGTACTAAGAAGCTCTGTAAAAAGAACAATG
AGACATTATGTAATGTTTGGTGACTTATTTTAAATCCAATTCGCATACCTTCGTAGTCGT
GCTTAAAGATTAAATTAGCTTGCCAAAGAAATGGCAGAAGAAATCCAAAATAACACTTTT
GACTAAAAAGTCTATAAAATTAAATTCGAAAAAGCAAATAAAAACTTTTTAGAGCCCGAG
TTTGAATAGCAAATAAGAAAAGATAGCAGCTATGTTAAAATATATGATGAATCTTTAGAA
GGAGAATAAAAATTTATGGGGTATCTTCCCAAAGAATGTTTGTATAAAAATCAATTATGA

>TTHERM_00348000(gene)
ATGAAAAAAAAGACTTAAAAAAAAGTAGAATAAACAAAAAGCTTAGTAGACAGGTTGAGG
TCAATTTAACTATGGCAAATTATACTAGGTATAATTGTCATATTATTGGCCAGAAATTTT
TATTTAAACAACGATTTGCATCCATAGCAGCAGAATTCAAATGAGTTTTCTTAAGATGAT
TATTATGTAGAAAATATGCATGGGGAAGCAAATTATATGCTTAAAGATAATCTCAAAAAA
TTGGCACACCCTGATGTTGGAAAATATAAAAAGAGAGTTTCTTAACCTTTGGATTAATTT
TGGTAAGGAAAGGAAAAAATAGCAGAAAGAATTGCTTCTCTCTTTAACGAATTTAATTAT
AAATAAATGGATTTGCAAATACATTTTGAAAATAGCAGAAACTATGATAGGCCCTCTTTA
GGTATAATCAGTGATCCTGAGTATTGTAAAAAAAGTAATATGCATCATATTTTGCATCCT
GAGTCAATTTAAAAAAACTATTTGATATTTACAGGTAAATAAATAAACATTAAAATGTTT
CTTTTTCCTCTTTTGAAGATATTTCTGATATGTTTTAAAAAGTTATTTTGATGATTTTAA
TGCCCCTAAATATAACCAAAAAATATCTTAATCAAAATATATTAATAAATTAATTAAAAG
TTAATAATAAAATTAATATCTGATGTATCTTTGCAAATTTTATCATTTAAAATATCATGT
TTAGGTTATTAATTAAATCAATAATTTAAAAAGATTTTGGATATAATGAATTGCCAAGAG
AGGTTGCTTAGCAATTTGGTGTTGACTTACTTCCTTAAGTTTCTTAGTAAATGAGTGATA
GAAAATAATAAGAAAGAGTATATAATCTACCAGTCGAAACTGCTTTGATTCACTCTAGAA
TATCTAGAATACACCATTTTTTTGAGTTTAATAAGAATATTATTTGCACATATTAATCAG
CAAATCATATTCCAGGTAAATGGTCTATCACTGGAAAAGATTTAGTCATAGATAATTACA
GACTTTACTAGTAAAAACCATTTATTAACAAGGATAAATGCTGGTAGCATGTTACATTTA
TGCCAGAGTCTTATCGTTTATACAATTCAAACGAATGCAAGAGTTTTTTCAAATTTCTTT
AATCAGATGAATACAAGGAATTAATCAAAAAAGATGGAATAGGATTTATAATGAAGTAGG
GAAGAGATATTCATCGTGGTTAAGGAATTAATTTAATTTCTCCTTAAATTTTGTAAGATT
TGATGAAGAAATACAATAACGGAAACAAGTGTGACTCTATTCATGAAGTTTATCAAGTTC
AAAGGTAGATAAAACACAATATAATTTTTTTTAAATTTAAAAATATTTTTAAATGCAACA
GGTACGTTAATAATCCTATATTGCATGATAACAAGAAGTTGGAAGTTCGTATTTACTTTT
TTATTGCAAGTACTGATCCTTTGATAATCTATGTTTAGAAATTAGCCCTTCTTAAAAAAT
GTGCCAGCGATTATAATAAATTCGATTATGATTTTTCTAGACATGTTTGCAATACCTCAA
TTAGTAAATAAATAACTGACTCATTCGTAGTTGAATTTGCTCTAGAAGGTTTAGAAAAGT
ACTTACTAGAAAACAATAAAATCACTAACCCTAAGTGGCTAGAAGAAGAAATTTATCCAT
AAATTTACAGAGCAGTCACACATTTGGTAAGATCTGGAGCTCATGATTTTTTGATTGACT
CTCGTGTGAATGAAAACTTTGCTTTAGACTTTTTGATAGATGAAGATTCAAAAGTATGGT
TCTTAGAAAATAATCCTAATCCTCAAGTACTAAGAAGCTCTGTAAAAAGAACAATGAGAC
ATTATGTAATGTTTGGTGACTTATTTTAAATCCAATTCGCATACCTTCGTAGTCGTGCTT
AAAGATTAAATTAGCTTGCCAAAGAAATGGCAGAAGAAATCCAAAATAACACTTTTGACT
AAAAAGTCTATAAAATTAAATTCGAAAAAGCAAATAAAAACTTTTTAGAGCCCGAGTTTG
AATAGCAAATAAGAAAAGATAGCAGCTATGTTAAAATATATGATGAATCTTTAGAAGGAG
AATAAAAATTTATGGGGTATCTTCCCAAAGAATGTTTGTATAAAAATCAATTATGA

>TTHERM_00348000(protein)
MKKKTQKKVEQTKSLVDRLRSIQLWQIILGIIVILLARNFYLNNDLHPQQQNSNEFSQDD
YYVENMHGEANYMLKDNLKKLAHPDVGKYKKRVSQPLDQFWQGKEKIAERIASLFNEFNY
KQMDLQIHFENSRNYDRPSLGIISDPEYCKKSNMHHILHPESIQKNYLIFTDFGYNELPR
EVAQQFGVDLLPQVSQQMSDRKQQERVYNLPVETALIHSRISRIHHFFEFNKNIICTYQS
ANHIPGKWSITGKDLVIDNYRLYQQKPFINKDKCWQHVTFMPESYRLYNSNECKSFFKFL
QSDEYKELIKKDGIGFIMKQGRDIHRGQGINLISPQILQDLMKKYNNGNKCDSIHEVYQV
QRYVNNPILHDNKKLEVRIYFFIASTDPLIIYVQKLALLKKCASDYNKFDYDFSRHVCNT
SISKQITDSFVVEFALEGLEKYLLENNKITNPKWLEEEIYPQIYRAVTHLVRSGAHDFLI
DSRVNENFALDFLIDEDSKVWFLENNPNPQVLRSSVKRTMRHYVMFGDLFQIQFAYLRSR
AQRLNQLAKEMAEEIQNNTFDQKVYKIKFEKANKNFLEPEFEQQIRKDSSYVKIYDESLE
GEQKFMGYLPKECLYKNQL