Identifiers and Description

Gene Model Identifier

TTHERM_00379000

Standard Name

EPC1 (EPiplasmin C 1 )

Aliases

EpiC | PreTt10354 | 40.m00239 | g24361

Description

EPC1 Epiplasmin C; the major protein component of the membrane skeleton (epiplasm); influences cell shape and the fidelity of cortical development; hypothetical protein

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

  • cortical cytoskeleton organization (IMP) | GO:0030865
  • establishment of chromatin silencing (IEA) | GO:0006343
  • galactose to glucose-1-phosphate metabolic process (IEA) | GO:0061612
  • glycolytic process from glycerol (IEA) | GO:0061613
  • glycolytic process through fructose-6-phosphate (IEA) | GO:0061615
  • heme A biosynthetic process (IEA) | GO:0006784
  • lipid homeostasis (IEA) | GO:0055088
  • maltoheptaose catabolic process (IEA) | GO:2001123
  • negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib (IEA) | GO:0002599
  • negative regulation of L-glutamine biosynthetic process (IEA) | GO:0062133
  • negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
  • negative regulation of phytoalexin metabolic process (IEA) | GO:0052321
  • obsolete bent DNA binding (IEA) | GO:0006326
  • obsolete negative regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway (IEA) | GO:0052479
  • obsolete regulation of histone H3-K79 methylation (IEA) | GO:2001160
  • obsolete regulation of nucleic acid-templated transcription (IEA) | GO:1903506
  • obsolete regulation of toxin transport (IEA) | GO:1902007
  • obsolete reproduction (IEA) | GO:0000003
  • obsolete response to long exposure to lithium ion (IEA) | GO:0043460
  • ommochrome biosynthetic process (IEA) | GO:0006727
  • plant-type cell wall modification (IEA) | GO:0009827
  • positive regulation of antigen processing and presentation of peptide antigen via MHC class Ib (IEA) | GO:0002597
  • positive regulation of forebrain neuron differentiation (IEA) | GO:2000979
  • pronephric glomerulus morphogenesis (IEA) | GO:0035775
  • pteridine biosynthetic process (IEA) | GO:0006728
  • regulation of antigen processing and presentation of lipid antigen via MHC class Ib (IEA) | GO:0002598
  • regulation of hemicellulose catabolic process (IEA) | GO:2000988
  • regulation of microglial cell migration (IEA) | GO:1904139

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:15134256: Williams NE (2004) The epiplasm gene EPC1 influences cell shape and cortical pattern in Tetrahymena thermophila. The Journal of eukaryotic microbiology 51(2):201-6
  2. Ref:12674474: Honts JE, Williams NE (2003) Novel cytoskeletal proteins in the cortex of Tetrahymena. The Journal of eukaryotic microbiology 50(1):9-14
  3. Ref:12674475: Huttenlauch I, Stick R (2003) Occurrence of articulins and epiplasmins in protists. The Journal of eukaryotic microbiology 50(1):15-8
  4. Ref:11112694: Bouchard P, Chomilier J, Ravet V, Mornon JP, Viguès B (2001) Molecular characterization of the major membrane skeletal protein in the ciliate Tetrahymena pyriformis suggests n-plication of an early evolutionary intermediate filament protein subdomain. Journal of cell science 114(Pt 1):101-110
  5. Ref:10571109: Bouchard P, Ravet V, Meiniel R, Creveaux I, Meiniel A, Vellet A, Vigues B (1999) Use of a heterologous monoclonal antibody for cloning and detection of glial fibrillary acidic protein in the bovine ventricular ependyma. Cell and tissue research 298(2):207-16
  6. Ref:9788878: Huttenlauch I, Peck RK, Stick R (1998) Articulins and epiplasmins: two distinct classes of cytoskeletal proteins of the membrane skeleton in protists. Journal of cell science 111 ( Pt 22)( ):3367-78
  7. Ref:7620468: Williams NE, Honts JE, Dress VM, Nelsen EM, Frankel J (1995) Monoclonal antibodies reveal complex structure in the membrane skeleton of Tetrahymena. The Journal of eukaryotic microbiology 42(4):422-7

Sequences 

>TTHERM_00379000(coding)
ATGTCTTATCAATACAGTCAAAACCTCGTTCAAAGCACCAACGTCCCACCTGGTAGCATT
CAATACTCCTAAAACAATATCCAAACTGCTGGACGTACCTTGATTGACTCTAGCTCCCCG
GAACATCCCATTCAATTGGCATCCAGCAACTAAGTCGTCAGCTAGATCCTCACCACCACT
TAAGGTTCTCCCACCAGACAATCCAAGACCTTCGTCTACAGATCTGAATCTCCTATTAGA
TCTTCTCAATACGGTAAGCACGTAGTCAATGTTTCTCACATTGAAAAGGGTCAAGCTCCC
ATTTACGTCTCCCAATCTACTGTCTAAAACCCTATCTACGTTGAAAAGATTGTTAAGGTC
GAAAGCAGTAACACTTCTGAACTCAACCTTCTCAGATAACGTATTTCAGCTTTGGAACTC
TAAAACAAGACCTTGACTGAAGAACTCATCACCTTAAGAAACAACACTCCTCAAGAAGTT
GAATAGATTGTTTACATTGAAAACAACGAAGAAATCAACAAATTGAGATATGAATTGAAC
AACATCAAGGCTCTCTCTGACGCTGAAAATGAAAACGTCAAGAGATCAAAGAAGAACTTG
GAAGACTAATTCAACTCAGTCTTACAAGAAAGAGACAGAATGATCATCTAACTTAAGGAA
TTAACTGTTAAGATCACTGAATTCTAATCCTTGATTGCCTCTAGAGATATCCAAATCAAC
AACTTAAAGATCTAAAACGAAAACCTTGCCACCAGACTCGTCCTCACTACTGCTGAATTA
GAAAAGATCACTCAAGTTAAGGTTGAAGCTGAACCTTTGAGAAGAAAGGTTACTGAACTC
GAATAATACTTGATTCAATAAGAAAAGATTATCGAGGACTTGAGAAATAGACTTGGCCAA
CAAGATCAAGTTATTTCTCAATTAAGAATGTTCGAAATCAGATGTTCCTAATACGAATAA
GAAATCAATGCTTTGAGAGCCAAGTTACAAGAATCTGAAAACAACTCTCTCCTCCTTATC
AAGAAGATTGAAGAATTACAAAACTTACTCAATGATGAAAACGTCAAGAGATCTAAGAAG
GATGGTGAACTCGCCATTTCTCTCAGAGACAAGCAAGCTCTTGAAGAAAAGCTTGTTCAC
TTGACTCAACAAGTCGAATTCTTAACAAGAAAGGTTGCTGCTCAAGAACAAGATATCAAT
GCCCAAAGAACTAGAATCATTGAGTTAGAAGGTATTGCTGCTAAGGTAGGATCTTACGAA
CAACAAATCTAATACCTCAGCCAACAAATCGAAAGATTGAACTAGGTTATTAGAGAAAAG
GACCAAACCATCACTCAACTTAACATTGAACTCAACCAACTCAGATTATCTAACTCTCAA
ATCGCTTAACTCTAAGAATAAGTCGTTACCTTATAACAAAACCTTGTTACTAGAACTGCT
GAAGTTGAATCTCTTAGAAAGAGAGTCTCTGAATAAGAACTCCTCATTAACTAACTCAGA
ATGTTTGAATAAAGAGTTGGTGAATATGAACAAATCATTAATGCTCTCAGATAGAGAATT
GCTGAACTTGAAGCTCAACTCAACGACGAAAACGTCAAGAGAAGCAAGAAGGACGGTGAA
CTCGCCATCTCCCTCAGAGACAAGCAAGCTCTTGAAGAAAAGCTCGTCCACATGACCCAA
CAAATTGAATTCTTATCTCAAAAGGTTAACTAATTAACTGGTCAAGTTGCTGAAAGAGAC
TAAATCATCAGCTAACTCAGAGTTTACGAAATCAGAGTTAAGGAATACGAAAATGTCATC
AACGCTCTTAGATAGAGAGTTGCTGAACTTGAAGCTCAACTCAACGACGAAAACGTCAAG
AGAAGCAAGAAGGACGGTGAACTCGCCATCTCCCTCAGAGACAAGCAAGCTCTTGAAGAA
AAGCTCGTTCACATGACCCAACAAATTGAATTCTTAAGCCAAAAGGTTGCTCAATACGAA
AAGATTCTTGGTGAACAATAATAATAACTCGCTGAAAGAGATAACATTATTAACTAACTC
AGAGTCTTCGAAATTAGAGTTAAGGAATACGAAAACGTCATCAACGCTCTTAGATAGAGA
GTTGCTGAACTTGAAGCTCAACTCAACGACGAAAACGTCAAGAGAAGCAAGAAGGACGGT
GAACTCGCCATCTCCCTCAGAGACAAGCAAGCTCTTGAAGAAAAGCTCGTTCACATGACC
TAGTAGATCGAATTCTTAAGCCAAAAGGTTGCCCAATACGAAAAGATCCTTGGTGAATAA
TAATAATAACTCGCTGAAAGAGACAACATCATTAACTAACTCAGAGTTTATGAAATCAGA
GTTAAGGAATACGAAAATGTCATCAACGCTCTTAGATAGAGAGTTTCTGAACTTGAAGCT
CAACTCAACGACGAAAACGTCAAGAGAAGCAAGAAGGACGGTGAACTCGCCATCTCCCTC
AGAGACAAGCAAGCCCTCGAAGAAAAGCTCGTCCACATGACCCAACAAATTGAATTCTTA
TCTCAAAAGGTTAACTAATTAACTGGTCAAGTTGCTGAAAGAGACAACATCATTAACTAA
CTCAGAGTTTATGAAATCAGAGTTAAGGAATACGAAAATGTTATCAACGCTCTTAGATAG
AGAGTTGCTGAACTTGAAGCTCAACTCAACGACGAAAACGTCAAGAGAAGCAAGAAGGAC
GGTGAACTCGCCATCTCCCTCAGAGACAAGCAAGCCCTCGAAGAAAAGCTCGTCCACATG
ACCTAATAGATTGAATTCTTGAACATGAAGGTCACTTCTTACGAAAAGTAAATCTAAGAA
AAGGATGGTCAAATTAACTAACTCAGAATCGAAATCTCTCAACTCCAAATCAACCTTCAA
TAATTGTAGAACGCTTCTGAAGAAGTCAGAAGACTCACTGAACTCCTCGTCGTTAAGACC
ACTGAAATCGACTAACTCAGAAAGAGATTAGCCGAATTAGAAATCGCCCTCTAGGAATTC
AACCTCGTCCAAGCTAAGCTCCAAGAATGTGAAAAGAATAACTAATTACTCAGATAGAGA
ATTGCTGAATTAGAAGCTCTCCTCAATGATGAAGCTGTTAAGAGATCTAGAAACCAAGGA
GATTTGGAAATTTCTTTGAGAGACAAGTAAGCCTTAGAAGAAAAGCTCGTCCACATGACT
CAACAAATCGAATTCTTAAGCAGAAAGGTTACCTAACTCACCGAAGAAAACTCCAACCTC
AGAGTTATCGTTTCTTCTTACTAACAAATCATCGATGAATGGTAATCCATCAGTGTCAGA
CACGCCAGCTTCTCCTAATTATTAGAAAACCTCAAGGTTAGAGTCCAACAAATCTCTTTC
TCTTCCTCTTCATCTTCCTAAGTTATTTCCCAATCTTCTTACGTCAGAAGCTCTGGTGTT
GCTCACAAGTGA



>TTHERM_00379000(gene)
ACTTTCCCAAAGGAAAAAAGTCCAGAAAAATTACAATAAAAAACAACAATTTCTTCAACA
AAAGAAAATGTCTTATCAATACAGTCAAAACCTCGTTCAAAGCACCAACGTCCCACCTGG
TAGCATTCAATACTCCTAAAACAATATCCAAACTGCTGGACGTACCTTGATTGACTCTAG
CTCCCCGGAACATCCCATTCAATTGGCATCCAGCAACTAAGTCGTCAGCTAGATCCTCAC
CACCACTTAAGGTTCTCCCACCAGACAATCCAAGACCTTCGTCTACAGATCTGAATCTCC
TATTAGATCTTCTCAATACGGTAAGCACGTAGTCAATGTTTCTCACATTGAAAAGGGTCA
AGCTCCCATTTACGTCTCCCAATCTACTGTCTAAAACCCTATCTACGTTGAAAAGATTGT
TAAGGTCGAAAGCAGTAACACTTCTGAACTCAACCTTCTCAGATAACGTATTTCAGCTTT
GGAACTCTAAAACAAGACCTTGACTGAAGAACTCATCACCTTAAGAAACAACACTCCTCA
AGAAGTTGAATAGATTGTTTACATTGAAAACAACGAAGAAATCAACAAATTGAGATATGA
ATTGAACAACATCAAGGCTCTCTCTGACGCTGAAAATGAAAACGTCAAGAGATCAAAGAA
GAACTTGGAAGACTAATTCAACTCAGTCTTACAAGAAAGAGACAGAATGATCATCTAACT
TAAGGAATTAACTGTTAAGATCACTGAATTCTAATCCTTGATTGCCTCTAGAGATATCCA
AATCAACAACTTAAAGATCTAAAACGAAAACCTTGCCACCAGACTCGTCCTCACTACTGC
TGAATTAGAAAAGATCACTCAAGTTAAGGTTGAAGCTGAACCTTTGAGAAGAAAGGTTAC
TGAACTCGAATAATACTTGATTCAATAAGAAAAGATTATCGAGGACTTGAGAAATAGACT
TGGCCAACAAGATCAAGTTATTTCTCAATTAAGAATGTTCGAAATCAGATGTTCCTAATA
CGAATAAGAAATCAATGCTTTGAGAGCCAAGTTACAAGAATCTGAAAACAACTCTCTCCT
CCTTATCAAGAAGATTGAAGAATTACAAAACTTACTCAATGATGAAAACGTCAAGAGATC
TAAGAAGGATGGTGAACTCGCCATTTCTCTCAGAGACAAGCAAGCTCTTGAAGAAAAGCT
TGTTCACTTGACTCAACAAGTCGAATTCTTAACAAGAAAGGTTGCTGCTCAAGAACAAGA
TATCAATGCCCAAAGAACTAGAATCATTGAGTTAGAAGGTATTGCTGCTAAGGTAGGATC
TTACGAACAACAAATCTAATACCTCAGCCAACAAATCGAAAGATTGAACTAGGTTATTAG
AGAAAAGGACCAAACCATCACTCAACTTAACATTGAACTCAACCAACTCAGATTATCTAA
CTCTCAAATCGCTTAACTCTAAGAATAAGTCGTTACCTTATAACAAAACCTTGTTACTAG
AACTGCTGAAGTTGAATCTCTTAGAAAGAGAGTCTCTGAATAAGAACTCCTCATTAACTA
ACTCAGAATGTTTGAATAAAGAGTTGGTGAATATGAACAAATCATTAATGCTCTCAGATA
GAGAATTGCTGAACTTGAAGCTCAACTCAACGACGAAAACGTCAAGAGAAGCAAGAAGGA
CGGTGAACTCGCCATCTCCCTCAGAGACAAGCAAGCTCTTGAAGAAAAGCTCGTCCACAT
GACCCAACAAATTGAATTCTTATCTCAAAAGGTTAACTAATTAACTGGTCAAGTTGCTGA
AAGAGACTAAATCATCAGCTAACTCAGAGTTTACGAAATCAGAGTTAAGGAATACGAAAA
TGTCATCAACGCTCTTAGATAGAGAGTTGCTGAACTTGAAGCTCAACTCAACGACGAAAA
CGTCAAGAGAAGCAAGAAGGACGGTGAACTCGCCATCTCCCTCAGAGACAAGCAAGCTCT
TGAAGAAAAGCTCGTTCACATGACCCAACAAATTGAATTCTTAAGCCAAAAGGTTGCTCA
ATACGAAAAGATTCTTGGTGAACAATAATAATAACTCGCTGAAAGAGATAACATTATTAA
CTAACTCAGAGTCTTCGAAATTAGAGTTAAGGAATACGAAAACGTCATCAACGCTCTTAG
ATAGAGAGTTGCTGAACTTGAAGCTCAACTCAACGACGAAAACGTCAAGAGAAGCAAGAA
GGACGGTGAACTCGCCATCTCCCTCAGAGACAAGCAAGCTCTTGAAGAAAAGCTCGTTCA
CATGACCTAGTAGATCGAATTCTTAAGCCAAAAGGTTGCCCAATACGAAAAGATCCTTGG
TGAATAATAATAATAACTCGCTGAAAGAGACAACATCATTAACTAACTCAGAGTTTATGA
AATCAGAGTTAAGGAATACGAAAATGTCATCAACGCTCTTAGATAGAGAGTTTCTGAACT
TGAAGCTCAACTCAACGACGAAAACGTCAAGAGAAGCAAGAAGGACGGTGAACTCGCCAT
CTCCCTCAGAGACAAGCAAGCCCTCGAAGAAAAGCTCGTCCACATGACCCAACAAATTGA
ATTCTTATCTCAAAAGGTTAACTAATTAACTGGTCAAGTTGCTGAAAGAGACAACATCAT
TAACTAACTCAGAGTTTATGAAATCAGAGTTAAGGAATACGAAAATGTTATCAACGCTCT
TAGATAGAGAGTTGCTGAACTTGAAGCTCAACTCAACGACGAAAACGTCAAGAGAAGCAA
GAAGGACGGTGAACTCGCCATCTCCCTCAGAGACAAGCAAGCCCTCGAAGAAAAGCTCGT
CCACATGACCTAATAGATTGAATTCTTGAACATGAAGGTCACTTCTTACGAAAAGTAAAT
CTAAGAAAAGGATGGTCAAATTAACTAACTCAGAATCGAAATCTCTCAACTCCAAATCAA
CCTTCAATAATTGTAGAACGCTTCTGAAGAAGTCAGAAGACTCACTGAACTCCTCGTCGT
TAAGACCACTGAAATCGACTAACTCAGAAAGAGATTAGCCGAATTAGAAATCGCCCTCTA
GGAATTCAACCTCGTCCAAGCTAAGCTCCAAGAATGTGAAAAGAATAACTAATTACTCAG
ATAGAGAATTGCTGAATTAGAAGCTCTCCTCAATGATGAAGCTGTTAAGAGATCTAGAAA
CCAAGGAGATTTGGAAATTTCTTTGAGAGACAAGTAAGCCTTAGAAGAAAAGCTCGTCCA
CATGACTCAACAAATCGAATTCTTAAGCAGAAAGGTTACCTAACTCACCGAAGAAAACTC
CAACCTCAGAGTTATCGTTTCTTCTTACTAACAAATCATCGATGAATGGTAATCCATCAG
TGTCAGACACGCCAGCTTCTCCTAATTATTAGAAAACCTCAAGGTTAGAGTCCAACAAAT
CTCTTTCTCTTCCTCTTCATCTTCCTAAGTTATTTCCCAATCTTCTTACGTCAGAAGCTC
TGGTGTTGCTCACAAGTGATTTTTCCAAAAAAGAAGCTCCTAAAATTTTTGTTGACCATT
ATTTGCAAAACATAAACAAACAAATTATATTAAAATTATGTATTTTCTATTTCTAAAAAC
AAACAATTTCATAGATTGCATTTATGTTTTTAATTTCTCTAAATTTTCATTT



>TTHERM_00379000(protein)
MSYQYSQNLVQSTNVPPGSIQYSQNNIQTAGRTLIDSSSPEHPIQLASSNQVVSQILTTT
QGSPTRQSKTFVYRSESPIRSSQYGKHVVNVSHIEKGQAPIYVSQSTVQNPIYVEKIVKV
ESSNTSELNLLRQRISALELQNKTLTEELITLRNNTPQEVEQIVYIENNEEINKLRYELN
NIKALSDAENENVKRSKKNLEDQFNSVLQERDRMIIQLKELTVKITEFQSLIASRDIQIN
NLKIQNENLATRLVLTTAELEKITQVKVEAEPLRRKVTELEQYLIQQEKIIEDLRNRLGQ
QDQVISQLRMFEIRCSQYEQEINALRAKLQESENNSLLLIKKIEELQNLLNDENVKRSKK
DGELAISLRDKQALEEKLVHLTQQVEFLTRKVAAQEQDINAQRTRIIELEGIAAKVGSYE
QQIQYLSQQIERLNQVIREKDQTITQLNIELNQLRLSNSQIAQLQEQVVTLQQNLVTRTA
EVESLRKRVSEQELLINQLRMFEQRVGEYEQIINALRQRIAELEAQLNDENVKRSKKDGE
LAISLRDKQALEEKLVHMTQQIEFLSQKVNQLTGQVAERDQIISQLRVYEIRVKEYENVI
NALRQRVAELEAQLNDENVKRSKKDGELAISLRDKQALEEKLVHMTQQIEFLSQKVAQYE
KILGEQQQQLAERDNIINQLRVFEIRVKEYENVINALRQRVAELEAQLNDENVKRSKKDG
ELAISLRDKQALEEKLVHMTQQIEFLSQKVAQYEKILGEQQQQLAERDNIINQLRVYEIR
VKEYENVINALRQRVSELEAQLNDENVKRSKKDGELAISLRDKQALEEKLVHMTQQIEFL
SQKVNQLTGQVAERDNIINQLRVYEIRVKEYENVINALRQRVAELEAQLNDENVKRSKKD
GELAISLRDKQALEEKLVHMTQQIEFLNMKVTSYEKQIQEKDGQINQLRIEISQLQINLQ
QLQNASEEVRRLTELLVVKTTEIDQLRKRLAELEIALQEFNLVQAKLQECEKNNQLLRQR
IAELEALLNDEAVKRSRNQGDLEISLRDKQALEEKLVHMTQQIEFLSRKVTQLTEENSNL
RVIVSSYQQIIDEWQSISVRHASFSQLLENLKVRVQQISFSSSSSSQVISQSSYVRSSGV
AHK