Identifiers and Description

Gene Model Identifier

TTHERM_00384910

Standard Name

CEN1 (CENtrin 1 )

Aliases

centrin | PreTt24783 | 41.m00190

Description

CEN1 basal body centrin protein; Centrin; EF Hand Ca2+ binding protein; alters MT sliding velocity to regulate ciliary beat form; localizes to basal bodies, oral apparatus cortical fibers, ciliary rootlets, the apical filament ring, and axonemal 14S inner arm dynein; hypothetical protein

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

  • ( SD03272 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::CEN1
  • ( SD03273 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-22
  • ( SD03274 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-29
  • ( SD03275 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-49
  • ( SD03276 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-58
  • ( SD03277 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-60
  • ( SD03278 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-86
  • ( SD03279 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-94
  • ( SD03280 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-103
  • ( SD03281 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-126
  • ( SD03282 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-134
  • ( SD03283 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-C-term∆
  • ( SD03284 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-EF1
  • ( SD03285 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-EF2
  • ( SD03286 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-EF1-EF2
  • ( SD03287 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-EF3
  • ( SD03288 ) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-EF3
  • ( SD03289 ) Micronucleus: cen1-1[∆::NEO2]
  • ( SD03290 ) Micronucleus: cen1-1[∆::NEO2]

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:21562224: Vonderfecht T, Stemm-Wolf AJ, Hendershott M, Giddings TH, Meehl JB, Winey M (2011) The two domains of centrin have distinct basal body functions in Tetrahymena. Molecular biology of the cell 22(13):2221-34
  2. Ref:17785518: Kilburn CL, Pearson CG, Romijn EP, Meehl JB, Giddings TH, Culver BP, Yates JR, Winey M (2007) New Tetrahymena basal body protein components identify basal body domain structure. The Journal of cell biology 178(6):905-12
  3. Ref:15944224: Stemm-Wolf AJ, Morgan G, Giddings TH, White EA, Marchione R, McDonald HB, Winey M (2005) Basal body duplication and maintenance require one member of the Tetrahymena thermophila centrin gene family. Molecular biology of the cell 16(8):3606-19
  4. Ref:16228897: Libusová L, Sulimenko T, Sulimenko V, Janisch R, Hozák P, Dráber P (2005) Distinct localization of a beta-tubulin epitope in the Tetrahymena thermophila and Paramecium caudatum cortex. Protoplasma 225(3-4):157-67
  5. Ref:15134263: McLaughlin NB, Buhse HE (2004) Localization by indirect immunofluorescence of tetrin, actin, and centrin to the oral apparatus and buccal cavity of the macrostomal form of Tetrahymena vorax. The Journal of eukaryotic microbiology 51(2):253-7
  6. Ref:12529441: Guerra C, Wada Y, Leick V, Bell A, Satir P (2003) Cloning, localization, and axonemal function of Tetrahymena centrin. Molecular biology of the cell 14(1):251-61
  7. Ref:12356864: Shang Y, Li B, Gorovsky MA (2002) Tetrahymena thermophila contains a conventional gamma-tubulin that is differentially required for the maintenance of different microtubule-organizing centers. The Journal of cell biology 158(7):1195-206

Sequences 

>TTHERM_00384910(coding)
ATGTCCCTCAAGAACACTAGACCCCCTGTTAAGTCCACCAGAGTCTCTCGTCCTCAATTG
ACTGAAGAATAAAAATAAGAAATTAAGGAAGCCTTCGATCTTTTCGATACCGATGGCACT
GGATATATTGATGCCAAGGAACTTAAGGTAGCAATGAGAGCTTTAGGATTTGAACCTAAA
AAGGAAGAAATCAAGAAAATGATTGCTGAAATCGACAGAGAAGGTCGTGGAGTTATTGAA
TTCTAAGACTTCCTTGATCTCATGACCGTTAAAATGGCTGAAAGAGATCCCAGAGATGAA
ATTTTAAAAGCTTTTAGATTATTTGATGATGATAATACTGGTAAGATCTCCTTAAAGAAT
TTAAAAAGAGTTGCCAGAGAATTGGGTGAAGCTATGACTGAAGAAGAACTCTAAGAAATG
ATTGATGAAGCTGATAGAGATGGTGATGGTGAAATTAGTGAGGAAGAATTCGTTAGAATT
ATGAAAAAGACCAACCTCTTCTGA



>TTHERM_00384910(gene)
AATTTAAAAAAATCAAAATATATTTATTTATACAAAAAGAAAAGTATATTCACAACTTAA
TTAAAATTCTTCACATAAGAAATGTCCCTCAAGAACACTAGACCCCCTGTTAAGTCCACC
AGAGTCTCTCGTCCTCAATTGACTGAAGAATAAAAATAAGAAATTAAGGAAGCCTTCGAT
CTTTTCGATACCGATGGCACTGGATATATTGATGCCAAGGAACTTAAGGTAGCAATGAGA
GCTTTAGGATTTGAACCTAAAAAGGAAGAAATCAAGAAAATGATTGCTGAAATCGACAGA
GAAGGTCGTGGAGTTATTGAATTCTAAGACTTCCTTGATCTCATGACCGTTAAAATGGCT
GAAAGAGATCCCAGAGATGAAATTTTAAAAGCTTTTAGATTATTTGATGATGATAATACT
GGTAAGATCTCCTTAAAGAATTTAAAAAGAGTTGCCAGAGAATTGGGTGAAGCTATGACT
GAAGAAGAACTCTAAGAAATGATTGATGAAGCTGATAGAGATGGTGATGGTGAAATTAGT
GAGGAAGAATTCGTTAGAATTATGAAAAAGACCAACCTCTTCTGATTTTCCTGTATAATC
AATCAATCAATCGATCAATAACAAACCAATAAACAAACAAATTAACCTCTATATATATTC
TTTCATCAAATATAATACATAATTTTTGCTAATTAACGTTACTCGTATCTATCCTTTTTC
ATATTTGTACTATGCTCATATTTTTATTATTGC



>TTHERM_00384910(protein)
MSLKNTRPPVKSTRVSRPQLTEEQKQEIKEAFDLFDTDGTGYIDAKELKVAMRALGFEPK
KEEIKKMIAEIDREGRGVIEFQDFLDLMTVKMAERDPRDEILKAFRLFDDDNTGKISLKN
LKRVARELGEAMTEEELQEMIDEADRDGDGEISEEEFVRIMKKTNLF