Identifiers and Description

Gene Model Identifier

TTHERM_00415780

Standard Name

NRK24 (NIMA-Related Kinase )

Aliases

PreTt13547 | 45.m00192 | 3833.m00745

Description

NRK24 Serine/Threonine kinase domain protein; NIMA-Related Kinase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• phosphorelay response regulator activity (IEA) | GO:0000156
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• phosphorelay signal transduction system (IEA) | GO:0000160
• protein phosphorylation (IEA) | GO:0006468
• regulation of DNA-templated transcription (IEA) | GO:0006355

Domains

• ( PF00069 ) protein kinase domain
• ( PF00072 ) response regulator receiver domain
• ( PF00610 ) Domain found in Dishevelled, Egl-10,
• ( PF07714 ) protein tyrosine kinase
• ( TIGR01387 ) heavy metal response regulator
• ( TIGR01818 ) nitrogen regulation protein NR(I)
• ( TIGR02154 ) phosphate regulon transcriptional regulatory protein
• ( TIGR02875 ) sporulation transcription factor Spo0A

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_06005.1	9.997093137033517e-262
	Description: protein kinase domain-containing protein (831 aa)
Oxytricha	Contig8286.0.g25	7.996706633065278e-159
	Description: Protein kinase domain
WormBase	WBGene00021461	3.000235161122315e-61
	Description: locus:nekl-1 status:Partially_confirmed UniProt:Q6AW07 protein_id:CCD69902.1
Stentor Coeruleus	SteCoe_21781	6.375869581278994e-59
	Description: None
DictyBase	DDB_G0289277	9.001131581050935e-57
	Description: nek4 on chromosome: 5 position 2561379 to 2563106
SGD	YDR523C	6.000354955737408e-39
	Description: SPS1 Putative protein serine/threonine kinase expressed at the end of meiosis and localized to the prospore membrane, required for correct localization of enzymes involved in spore wall synthesis

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00415780(coding)
ATGGCGGATAGATCATATTAAAGTATTCATGTTTTAGTCGCAGAGGATGATAATTTCCAA
AGATTAGCTCTTATAGATATTTTGACCCTTTGCGATTACCAAGTTACTGCTGTAGAAAAC
GGAAGATTAGCTAGGGATGAACTCTTAAAAGCAGATTCAAATATTGATATTGTTCTTTTA
GATCTATACATGCCAGAGATGGATGGTATTGAGTTATTATTATTAATGTAAGAACATGAA
CATTTAAAAAGAATTCCTGTAATTATGATGAGTTTCGATAATGAATAAGAAAGAGTTGCC
TATTGTATTGCAAATGGAGCTAAAGATTATCTTGTTAAACCTCTTAGAATTTAAAACGTT
AAAGGTTTAGCAAAATATGTGGAATATAATCCAAACAATACCACAGTAGGAAATGGAGGA
GTTGGTTTATAGTCTTATAAAGTAATTAGAATGATTGGTTAAGGCGCAGGAGGAAGTGTA
GAGTTAGTTTAAAAAAGAAGCGATGGATAACTTTTTGCTCTCAAAACTATTAGTATGAAA
TTCATGGATGACTAGTAAAAAAAAATGGCATAACAGGAAATCACCTTGTTAAAAGTGCTT
GTTGCTCCTTCTATAATTCGTTATTATGAATCTTTTGTGGAAAATGATTCGATTCACATT
ATCATGGAATACGCTAAAGAAGGTGCCTTAAGCGATAAAATTACAGAACATAAATAAAAA
GGAATACCTATAGATGAAGAAACAGTTTTATATTTCACAGCATAGATTATTATTTCAGTG
CTTTTTATGCACTCTAAAAACATTTTGCACAGAGATATTAAAACTTAAAATCTCTTTTTG
ACCAAAGAAAATATAGTTAAGTTAGGAGATTTTGGTATCTCTAAAGAATTAGGTACAAAT
GCAAACGCAAAGACATTAGTTGGTACACCTTATTTCATGTCTCCTGAAGTATGCAGTGGT
GAAAATTATGGATAAAAAGCAGATATTTGGGCTATAGGGTGCACTTTGTACGAAATGGTC
ATGCTGAAAAGACCTTTTGATAACGATAACTTGAATATTCTTTTCAATAAAATTAGATTT
GAAGCTCCTCCTCCTTTACATGAAAATACTAGTACTGAAATACGTATGCTTATAACATTC
ATGCTTTAAAAGGACCCAGTAAAAAGACCTTCTGTTTGGGATTTGGCTAAAATTCCTATC
ATATCTAAAAATATCAGAAAATATTATGAAGAAGAAGCTCAAGATGATCCATTTTTAAAG
GAATATATCTTTTCTGGACCTAAAAATCACCCAAATATAAATAAAAATGTGCCAAAAGAC
GAAAAGAAAAATACAAGCGATAATACTTCAAAAACTTAAGATTAGTCTTAAAACACAAAT
GAAGAGATGTTTAAAGCTCTTAGTTCCGCTTTGTCTCCTTATGACTAGAAAATTAGCATG
TTTAAGGTTGAAAGAAACGTCATAAATGGAAAGTAGTTATTTTAATGGATTTAGCAATAC
TATACAAATTACAATACTTCTCAGGTAGTTGAAATGTTGAATGAGTTAGTTGAGAAAAAA
TATCTTCACCACATTGCTGGTCCTTTGCATCAATCTGATCCAAATTCTTTATATAGATTC
TAATTTGATATGCCAGGAATTGCAGCTAATCTGACAAGAATTTGGAATAAGACTGCTAGA
CCTGCTCTTTAATGTCTTTAGGGAATTGTAGAAACTGCAAATGAAGTATTAACTGAAGTT
ACAGATAAGCTGGAAGGAAAGGTTTTTGATGATAAGCTATATCAAAATAAAAAATATATC
AAATTCTTAGAATTGGTTTGTGAGCTGTAAAAAATTTATTTGTAAGATACTAATGAACAA
GAGAGAAAGTGCATTTTTATCAATTTACTCTAAATTATGTATTTCCATAAATTCATGAAG
CAAAGATACATCAGAATGAGGAACGAAAAGAAAGAAAAAGTCACTACTCTTTTTGAGACT
TTAGCATCATTTTTGCCTTTCTTTAGCAAAAGTTAAGATGAATTTTACTATACTATTGGT
AACCTTTAATTCACATTAGATGACATTAAGCATGGTATAATAAGAGGTAATAAGACTCAA
AAATTAAGCTCATTTAAGCCATTTGCAGACAACGATAGTAGGAAATAATTTGTTCTAACT
CCAGATTTAAGAATTTTGATGCTTTTTAAAGAAGAAAATGTCATTCCAACTGAGTTGAAA
TATATAAAATTAGAAACTATGGAATAGTAGTTAAATGAAATTTGCAATAAATTTTTGAGC
ACATACGTGTACATAGATAATATAGAAAATGATCTAACTATGCATAAGATATTCTAAATA
TATCAAAGCGATTTCGGCCCAGAACCATAAGATGCAATAGTGTGGGCTTCAAACTACACT
AAAAATCTAGGTAGAGTAGACGATTTAGTTTAAAATATAAAATCAGGAGATATATTTGTA
TAGTATTAAGAAAAATTTGAATCCTGA

>TTHERM_00415780(gene)
ATGGCGGATAGATCATATTAAAGTATTCATGTTTTAGTCGCAGAGGATGATAATTTCCAA
AGATTAGCTCTTATAGATATTTTGACCCTTTGCGATTACCAAGTTACTGCTGTAGAAAAC
GGAAGATTAGCTAGGGATGAACTCTTAAAAGCAGATTCAAATATTGATATTGTTCTTTTA
GATCTATACATGCCAGAGATGGATGGTATTGAGTTATTATTATTAATGTAAGAACATGAA
CATTTAAAAAGAATTCCTGTAATTATGATGAGTTTCGATAATGAATAAGAAAGAGTTGCC
TATTGTATTGCAAATGGAGCTAAAGATTATCTTGTTAAACCTCTTAGAATTTAAAACGTT
AAAGGTACAATAATTATTTTAAGTGGGTATTAAAATTATAAAATATGAAAAATAAAATAA
AAAAAAACAAATAGCTGATCTGCAAAATAAGTTTGAAGCTTTTTCTTACTACTTTATCAA
TGCATTTAATTAAATATAGCTAAATATCCCTATTTTAAGAATAGAATGTCTTCCTTTATA
ATATATGAACTAATATCATTTAGTTTTTATGAATTAAATTTTAATTTGATCTATAAAATT
ATGAATTGAAATCCAATAAAATCATGTCTGCAGCATTCAGAAGTTATATATTTTTTTAAA
AATATTTGTAGGTTTAGCAAAATATGTGGAATATAATCCAAACAATACCACAGTAGGAAA
TGGAGGAGTTGGTTTATAGTCTTATAAAGTAATTAGAATGATTGGTTAAGGCGCAGGAGG
AAGTGTAGAGTTAGTTTAAAAAAGAAGCGATGGATAACTTTTTGCTCTCAAAACTATTAG
TATGAAATTCATGGATGACTAGTAAAAAAAAATGGCATAACAGGAAATCACCTTGTTAAA
AGTGCTTGTTGCTCCTTCTATAATTCGTTATTATGAATCTTTTGTGGAAAATGATTCGAT
TCACATGTAAATATATAGAAAATATTAACAAAATGTTAAAAAATGTTTAACTAAAATCTT
ATTTTTTATTAGTATCATGGAATACGCTAAAGAAGGTGCCTTAAGCGATAAAATTACAGA
ACATAAATAAAAAGGAATACCTATAGATGAAGAAACAGTTTTATATTTCACAGCATAGAT
TATTATTTCAGTGCTTTTTATGCACTCTAAAAACATTTTGCACAGAGATATTAAAACTTA
AAATCTCTTTTTGACCAAAGAAAATATAGTTAAGTTAGGAGATTTTGGTATCTCTAAAGA
ATTAGGTACAAATGCAAACGCAAAGACATTAGTTGGTACACCTTATTTCATGTCTCCTGA
AGTATGCAGTGGTGAAAATTATGGATAAAAAGCAGATATTTGGGCTATAGGGTGCACTTT
GTACGAAATGGTCATGCTGAAAAGACCTTTTGATAACGATAACTTGAATATTCTTTTCAA
TAAAATTAGATTTGAAGTATTAATAAAATGTTAGCGCAATTGTTTTATATCATTTTAAAT
AATAAATAAAATAGGCTCCTCCTCCTTTACATGAAAATACTAGTACTGAAATACGTATGC
TTATAACATTCATGCTTTAAAAGGACCCAGTAAAAAGACCTTCTGTTTGGGATTTGGCTA
AAATTCCTATCATATCTAAAAATATCAGAAAATATTATGAAGAAGAAGCTCAAGATGATC
CATTTTTAAAGGAATATATCTTTTCTGGACCTAAAAATCACCCAAATATAAATAAAAATG
TGCCAAAAGACGAAAAGAAAAATACAAGCGATAATACTTCAAAAACTTAAGATTAGTCTT
AAAACACAAATGAAGAGATGTTTAAAGCTCTTAGTTCCGCTTTGTCTCCTTATGACTAGA
AAATTAGCATGTTTAAGGTTGAAAGAAACGTCATAAATGGAAAGTAGTTATTTTAATGGA
TTTAGCAATACTATACAAATTACAATACTTCTCAGGTAGTTGAAATGTTGAATGAGTTAG
TTGAGAAAAAATATCTTCACCACATTGCTGGTCCTTTGCATCAATCTGATCCAAATTCTT
TATATAGATTCTAATTTGATATGCCAGGAATTGCAGCTAATCTGACAAGAATTTGGAATA
AGACTGCTAGACCTGCTCTTTAATGTCTTTAGGGAATTGTAGAAACTGCAAATGAAGTAT
TAACTGAAGTAATTATACTAACTATTTAAAAAAAAGCAAAAAATAAATTTATTTCCTTAA
TTTTTAATATGATAAATAGGTTACAGATAAGCTGGAAGGAAAGGTTTTTGATGATAAGCT
ATATCAAAATAAAAAATATATCAAATTCTTAGAATTGGTTTGTGAGCTGTAAAAAATTTA
TTTGTAAGATACTAATGAACAAGAGAGAAAGTGCATTTTTATCAATTTACTCTAAATTAT
GTATTTCCATAAATTCATGAAGCAAAGATACATCAGAATGAGGAACGAAAAGAAAGAAAA
AGTCACTACTCTTTTTGAGACTTTAGCATCATTTTTGCCTTTCTTTAGCAGTATAATTGA
TCATTTATTTATTAATTCATATATTAAGTAGTTCTTTTACTAATATTAGAAAGTTAAGAT
GAATTTTACTATACTATTGGTAACCTTTAATTCACATTAGATGACATTAAGCATGGTATA
ATAAGAGGTAATAAGACTCAAAAATTAAGCTCATTTAAGCCATTTGCAGACAACGATAGT
AGGAAATAATTTGTTCTAACTCCAGATTTAAGAATTTTGATGCTTTTTAAAGAAGAAAAT
GTCATTCCAACTGAGTTGAAATATATAAAATTAGAAACTATGGAATAGTAGTTAAATGAA
ATTTGCAATAAATTTTTGAGCACATACGTGTACATAGATAATATAGAAAATGATCTAACT
ATGCATAAGATATTCTAAATATATCAAAGCGATTTCGGCCCAGAACCATAAGATGCAATA
GTGTGGGCTTCAAACTACACTAAAAATCTAGGTAGAGTAGACGATTTAGTTTAAAATATA
AAATCAGGAGATATATTTGTATAGTATTAAGAAAAATTTGAATCCTGA

>TTHERM_00415780(protein)
MADRSYQSIHVLVAEDDNFQRLALIDILTLCDYQVTAVENGRLARDELLKADSNIDIVLL
DLYMPEMDGIELLLLMQEHEHLKRIPVIMMSFDNEQERVAYCIANGAKDYLVKPLRIQNV
KGLAKYVEYNPNNTTVGNGGVGLQSYKVIRMIGQGAGGSVELVQKRSDGQLFALKTISMK
FMDDQQKKMAQQEITLLKVLVAPSIIRYYESFVENDSIHIIMEYAKEGALSDKITEHKQK
GIPIDEETVLYFTAQIIISVLFMHSKNILHRDIKTQNLFLTKENIVKLGDFGISKELGTN
ANAKTLVGTPYFMSPEVCSGENYGQKADIWAIGCTLYEMVMLKRPFDNDNLNILFNKIRF
EAPPPLHENTSTEIRMLITFMLQKDPVKRPSVWDLAKIPIISKNIRKYYEEEAQDDPFLK
EYIFSGPKNHPNINKNVPKDEKKNTSDNTSKTQDQSQNTNEEMFKALSSALSPYDQKISM
FKVERNVINGKQLFQWIQQYYTNYNTSQVVEMLNELVEKKYLHHIAGPLHQSDPNSLYRF
QFDMPGIAANLTRIWNKTARPALQCLQGIVETANEVLTEVTDKLEGKVFDDKLYQNKKYI
KFLELVCELQKIYLQDTNEQERKCIFINLLQIMYFHKFMKQRYIRMRNEKKEKVTTLFET
LASFLPFFSKSQDEFYYTIGNLQFTLDDIKHGIIRGNKTQKLSSFKPFADNDSRKQFVLT
PDLRILMLFKEENVIPTELKYIKLETMEQQLNEICNKFLSTYVYIDNIENDLTMHKIFQI
YQSDFGPEPQDAIVWASNYTKNLGRVDDLVQNIKSGDIFVQYQEKFES