Identifiers and Description

Gene Model Identifier

TTHERM_00434040

Standard Name

RPS12 (Ribosomal Protein of the Small subunit )

Aliases

ribosomal protein S12 | S25 | PreTt26545 | 48.m00308 | 3831.m01641 | RPS23

Description

RPS12 40S ribosomal protein S23; Homolog of yeast RPS23- human RPS23 and bacterial RPS12; small (40S) ribosomal subunit protein with sequence similarity to E.coli ribosomal protein S12

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cytosolic small ribosomal subunit (sensu Eukaryota) (ISS) | GO:0005843
• intracellular anatomical structure (IEA) | GO:0005622
• ribosome (IEA) | GO:0005840

Molecular Function

• structural constituent of ribosome (ISS) | GO:0003735
• structural constituent of ribosome (IEA) | GO:0003735

Biological Process

• translation (ISS) | GO:0006412
• translation (IEA) | GO:0006412

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_04231.1	2.999180586171967e-98
	Description: ribosomal protein S25 (143 aa)
WormBase	WBGene00004492	3.0012565309061457e-65
	Description: locus:rps-23 40S ribosomal protein S23 status:Confirmed UniProt:Q19877 protein_id:CAA94601.1
SGD	YPR132W	3.9989468726312675e-65
	Description: RPS23B Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Ap and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal
Oxytricha	Contig12890.0.g103	6.000608367221491e-63
	Description: Ribosomal protein S12
DictyBase	DDB_G0272250	2.9997246065828143e-59
	Description: rps23 on chromosome: 2 position 1373618 to 1374599
Stentor Coeruleus	SteCoe_33685	5.380186160021138e-32
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:21205638: Rabl J, Leibundgut M, Ataide SF, Haag A, Ban N (2011) Crystal structure of the eukaryotic 40S ribosomal subunit in complex with initiation factor 1. Science (New York, N.Y.) 331(6018):730-6
2. Ref:8496146: Alksne LE, Warner JR (1993) A novel cloning strategy reveals the gene for the yeast homologue to Escherichia coli ribosomal protein S12. The Journal of biological chemistry 268(15):10813-9
3. Ref:8415737: Alksne LE, Anthony RA, Liebman SW, Warner JR (1993) An accuracy center in the ribosome conserved over 2 billion years. Proceedings of the National Academy of Sciences of the United States of America 90(20):9538-41
4. Ref:1459144: Nørgaard P, Dreisig H, Kristiansen K (1992) Chromatin structure and conserved sequence elements in genes encoding ribosomal proteins in Tetrahymena thermophila. European journal of biochemistry 210(2):621-7
5. Ref:16453715: Nielsen H, Andreasen PH, Dreisig H, Kristiansen K, Engberg J (1986) An intron in a ribosomal protein gene from Tetrahymena. The EMBO journal 5(10):2711-7

Sequences

>TTHERM_00434040(coding)
ATGGGTGTTGGTAAACCTAGAGGTATTAGAGCCGGTAGAAAATTGGCTAGACACAGAAAG
GACCAAAGATGGGCTGATAACGATTTCAACAAGAGACTTTTGGGCTCCAGATGGAGAAAT
CCTTTTATGGGTGCTTCTCACGCTAAGGGTTTAGTCACTGAAAAGATCGGTATTGAATCT
AAGCAACCTAACTCTGCCGTCAGAAAGTGTGTTAGAGTTTTGCTCAGAAAGAACTCCAAG
AAGATCGCTGCTTTCGTTCCTATGGATGGTTGCCTTAACTTCTTAGCTGAAAACGACGAA
GTCTTGGTTGCTGGTCTTGGTAGACAAGGTCACGCCGTCGGTGATATTCCGGGTGTTAGA
TTCAAAGTTGTTTGTGTCAAGGGTATTTCTCTCTTGGCTCTTTTCAAGGGTAAGAAGGAA
AAGCGTTGA

>TTHERM_00434040(gene)
ATGGGTGTTGGTAAACCTAGAGGTATTAGAGCCGGTAGAAAATTGGCTAGACACAGAAAG
GACCAAAGGTGAAATATTTTTTTAATAACAATCAATCTACAGCAAGCATGAATCTGAGGA
GTGTTGCATCAAAGCTATAGCAATCCTTCTCTTTATTTTTCAAAACGCTCTCAAATGAAT
GATAAATCAATTACAAATCCATTCCATTACATTCCCCAATTTTGACAAACATTTAAAAAT
TATTTTTATTCATTCTCATCAATTTTGTTAAATGCATCTAATTAATGTCTTCAACCAACA
ATTCTACTAAGATATAATCGTTTCTCTGCGCTTAGTTTGCTTTATCCTTCTTACGGACCT
ATTGAAAATATTTTGTATATAGCTCAAAAAGCCAAATAATCTTTAATAAATAAAAGCAGA
CAGATTTTGTTTTATTTTTTGAGTTAGAATCTGAATTCTAAAGTTTCTAGCTAACTTTCA
ATCAACAAAGCTGTTGCAAAGATTTAAGAAATAGAATAAAAAGCAAACCCCTAAATTAGA
TTATTTGAAATAATTAGGTTTTTATCTAGAATGATTGATTGAAATTCTCAGATTGAATAT
TAATCGATCAAATTACAAAAATTATGAACTATATATAAAATAGAAGTTAAATAGAGGAGA
CTATGTATAACAAAAGCAGCAATAAATAAATAAATGAACAAATGGTTTGATAAAGCATTT
AGTAAAATTAAAGAGCATTAACGCTTTATAACGAATTTGAAAAATGAATGTTTAAAAATG
AATAATAAATAGGTTTGTTGTTTGTAATTTCCAAATAAATTTTACTTGAAATTTTTGTCT
TTTGAAAGAAAGATCTCAACTAACTTTAACAAGCATATAAACTAATAAAGATTTTTGCTT
AATTTATTTCGAAGGATGGATGGATATAAAAATATCATCTTAAAAGATAAGCGGATATGA
AAACATAAACAAATTAATAAAAAAATAAATGATTGCTTGCCATTATTCTCTTCCTCTCAA
AATAAATTTATTAAATTCAATTTTAAATAAAAAGATGGGCTGATAACGATTTCAACAAGA
GACTTTTGGGCTCCAGATGGAGAAATCCTTTTATGGGTGCTTCTCACGCTAAGGGTTTAG
TCACTGAAAAGATCGGTATTGAATCTAAGCAACCTAACTCTGCCGTCAGAAAGTGTGTTA
GAGTTTTGCTCAGAAAGAACTCCAAGAAGATCGCTGCTTTCGTTCCTATGGATGGTTGCC
TTAACTTCTTAGCTGAAAACGACGAAGTCTTGGTTGCTGGTCTTGGTAGACAAGGTCACG
CCGTCGGTGATATTCCGGGTGTTAGATTCAAAGTTGTTTGTGTCAAGGGTATTTCTCTCT
TGGCTCTTTTCAAGGGTAAGAAGGAAAAGCGTTGA

>TTHERM_00434040(protein)
MGVGKPRGIRAGRKLARHRKDQRWADNDFNKRLLGSRWRNPFMGASHAKGLVTEKIGIES
KQPNSAVRKCVRVLLRKNSKKIAAFVPMDGCLNFLAENDEVLVAGLGRQGHAVGDIPGVR
FKVVCVKGISLLALFKGKKEKR