Identifiers and Description

Gene Model Identifier

TTHERM_00437370

Standard Name

CTH6 (CaTHepsin 6)

Aliases

PreTt05393 | 49.m00165 | 3708.m00015

Description

CTH6 eukaryotic aspartyl protease

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• aspartic-type endopeptidase activity (IEA) | GO:0004190

Biological Process

• proteolysis (IEA) | GO:0006508

Domains

• ( PF00026 ) Eukaryotic aspartyl protease
• ( TIGR00081 ) phosphoribosylaminoimidazolesuccinocarboxamide synthase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_12488.1	9.997093137033517e-262
	Description: eukaryotic aspartyl protease (391 aa)
Oxytricha	Contig19103.0.g52	8.001993295941272e-61
	Description: Eukaryotic aspartyl protease
DictyBase	DDB_G0279411	1.0001055852164665e-60
	Description: ctsD on chromosome: 3 position 2104523 to 2105867
WormBase	WBGene00000217	1.9999167998962255e-60
	Description: locus:asp-4 status:Confirmed UniProt:Q21966 protein_id:CAA90633.1
WormBase	WBGene00006798	1.9999167998962255e-60
	Description: locus:unc-64 Syntaxin-1A homolog status:Confirmed UniProt:O16000 protein_id:CAC42303.1
SGD	YPL154C	9.995951036711152e-55
	Description: PEP4 Vacuolar aspartyl protease (proteinase A), required for the posttranslational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; synthesized as a zymogen, self-activates
Stentor Coeruleus	SteCoe_13816	9.854154686111257e-34
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00437370(coding)
ATGAGTAAAACAATTATTGTCCTTATTTTAGCCTTTGCTTTATGCTCAGCCTCAGTTATC
CGTATTCCTATCAAGAAGAGAGCTAGAACTGAATTATAAGATGAAATCTTATACAAAAAA
CTCGAACGTAAAGAAAGAGGTTTCTTGGATCAAATTTTAAACTCTGATGAAGATATACCT
AGTTATCCTGAAATCAAGGTTTAAAACTACTTGGATATGTCATATTATGGTGAAATTTCT
ATTGGTACTCCTCCTCAACCATTTGTCATTCTCTTCGATACAGGTTCTTCTGACTTGTGG
GTTCCTGGAAAACCTTGCATTTCTTTACCTTGCTTAGTTCACCCTAAATTCAATACTCAA
AAATCTAGCACTTACAATGAAAGCGCTTAAAAATTCTCACTCGTTTATGGCTCTGGTGCA
GTAACTGGTCATTTAGCTACTGAAACTGTTACTCTTGGACCTCTCTAAGCTTAAAATGTT
ACCTTCGGTTTGGCTAAAACCTTGACCTCTGCCTTTGAAACTACCAAATTTGATGGTATA
TTAGGTTTAGCTTATAAGGAATTATCTGGCTTCAAAGCTAACACTTTCTTTGATGAGTTA
GTTGCTTAAAAGTAAGTTGCCAGTAACCTTTTCTCTTTATATTTGAGCGACAAAGAAAAC
AGTGATGATTCTGAATTAATTTTGGGTGGAATTGACTAATCTTATGCCTCTAGTGAATTT
AAGTTCTACCCTGTTATCCTTAAGGCTTGGTATGTTATTGCTGCTAACTCAATCTCAGTT
GGCAACCTCAACTTATAACTTGATTCTATGATAGTCGATAGTGGTTCTAGTGTTGTTTTT
GGTGTTCCCGAGGTTATCAATCCTATCATTCAGCTTTTCCCTAAAAACATTGATTGTGGT
TCCATTAGCTAATATCCTAATGTAACCATTAATATTTCTGGTGATGACTATGTTCTTGAA
CCTGTTGACTATATTGTTCAAATCGAATATAAGGGAAGAACCCAATGTTAACTCGGTTTT
GCTGCAACTAAACTATCTAAGCAATTAGGTAATGCCCTTATCTTAGGTGACACTTTCTTC
AGAAAGTATTACACAGCTTATGATAGAGAAAATAATCGTGTCGGCTTTGCTATTGCTAAC
CATAACAATAACAAAAAAGCTTAAAAATTGATTTGA

>TTHERM_00437370(gene)
ATGAGTAAAACAATTATTGTCCTTATTTTAGCCTTTGCTTTATGCTCAGCCTCAGTTATC
CGTATTCCTATCAAGAAGAGAGCTAGAACTGAATTATAAGATGAAATCTTATACAAAAAA
CTCGAACGTAAAGAAAGAGGTTTCTTGGATCAAGTAATACTTTTCTTTAAACTTTTATTT
AATATAATTTTTTTATATTAAAATTAGATTTTAAACTCTGATGAAGATATACCTAGTTAT
CCTGAAATCAAGGTTTAAAACTACTTGGATATGTCATATTATGGTGAAATTTCTATTGGT
ACTCCTCCTCAACCATTTGTCATTCTCTTCGATACAGGTTCTTCTGACTTGTGGGTTCCT
GGAAAAGTATTTAAAAATATTATTAAAAAATATTGTTTAAATTAATTAAAATTAAAAATA
GCCTTGCATTTCTTTACCTTGCTTAGTTCACCCTAAATTCAATACTCAAAAATCTAGCAC
TTACAATGAAAGCGCTTAAAAATTCTCACTCGTTTATGGCTCTGGTGCAGTAACTGGTCA
TTTAGCTACTGAAACTGTTACTCTTGGACCTCTCTAAGCTTAAAATGTTACCTTCGGTTT
GGCTAAAACCTTGACCTCTGCCTTTGAAACTACCAAATTTGATGGTATATTAGGTTTAGC
TTATAAGGAATTATCTGGCTTCAAAGCTAACACTTTCTTTGATGAGTTAGTTGCTTAAAA
GTAAGTTGCCAGTAACCTTTTCTCTTTATATTTGAGCGACAAAGAAAACAGTGATGATTC
TGAATTAATTTTGGGTGGAATTGACTAATCTTATGCCTCTAGTGAATTTAAGTTCTACCC
TGTTATCCTTAAGGCTTGGTATGTTATTGCTGCTAACTCAATCTCAGTTGGCAACCTCAA
CTTATAACTTGATTCTATGATAGTCGATAGTGGTTCTAGTGTTGTTTTTGGTGTTCCCGA
GGTTATCAATCCTATCATTCAGCTTTTCCCTAAAAACATTGATTGTGGTTCCATTAGCTA
ATATCCTAATGTAACCATTAATATTTCTGGTGATGACTATGTTCTTGAACCTGTTGACTA
TATTGTTCAAATCGAATATAAGGGAAGAACCCAATGTTAACTCGGTTTTGCTGCAACTAA
ACTATCTAAGCAATTAGGTAATGCCCTTATCTTAGGTGACACTTTCTTCAGAAAGTATTA
CACAGCTTATGATAGAGAAAATAATCGTGTCGGCTTTGCTATTGCTAACCATAACAATAA
CAAAAAAGCTTAAAAATTGATTTGA

>TTHERM_00437370(protein)
MSKTIIVLILAFALCSASVIRIPIKKRARTELQDEILYKKLERKERGFLDQILNSDEDIP
SYPEIKVQNYLDMSYYGEISIGTPPQPFVILFDTGSSDLWVPGKPCISLPCLVHPKFNTQ
KSSTYNESAQKFSLVYGSGAVTGHLATETVTLGPLQAQNVTFGLAKTLTSAFETTKFDGI
LGLAYKELSGFKANTFFDELVAQKQVASNLFSLYLSDKENSDDSELILGGIDQSYASSEF
KFYPVILKAWYVIAANSISVGNLNLQLDSMIVDSGSSVVFGVPEVINPIIQLFPKNIDCG
SISQYPNVTINISGDDYVLEPVDYIVQIEYKGRTQCQLGFAATKLSKQLGNALILGDTFF
RKYYTAYDRENNRVGFAIANHNNNKKAQKLI