Identifiers and Description

Gene Model Identifier

TTHERM_00439250

Standard Name

GIP1 (Granule-biosynthesis Induced Protease 1)

Aliases

PreTt05482 | 49.m00254 | 3708.m00103

Description

GIP1 papain family cysteine protease; Granule-biosynthesis induced protease; putative cysteine protease; transcription induced following exocytosis; putative cargo protein of dense core secretory granules

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• dense core granule (IDA) | GO:0031045

Molecular Function

• cysteine-type peptidase activity (IEA) | GO:0008234

Biological Process

• proteolysis (IEA) | GO:0006508
• vesicle organization (IEP) | GO:0016050

Domains

• ( PF00112 ) Papain family cysteine protease
• ( PF02218 ) Repeat in HS1/Cortactin
• ( PF08246 ) Cathepsin propeptide inhibitor domain (I29)

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_06987.1	1.99972299831384e-147
	Description: papain family cysteine protease containing protein (344 aa)
Oxytricha	Contig1254.0.g80	8.003186242472315e-51
	Description: Papain family cysteine protease
DictyBase	DDB_G0290957	8.003782782428492e-46
	Description: cprA on chromosome: 5 position 4812963 to 4814596
WormBase	WBGene00000776	2.0005131442217614e-40
	Description: locus:cpl-1 status:Confirmed UniProt:O45734 protein_id:CAB07275.1
Stentor Coeruleus	SteCoe_27084	2.6102790696677047e-23
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:12456006: Haddad A, Bowman GR, Turkewitz AP (2002) New class of cargo protein in Tetrahymena thermophila dense core secretory granules. Eukaryotic cell 1(4):583-93

Sequences

>TTHERM_00439250(coding)
ATGATACTCAAACATATCATCAATTAAATAAAATATTTACTAGAACGAACGGTAAGCTTT
AAATCTTGGATATTTTAGTCATAAAATTTATAAAAATTATAAAACAAAAAAACTAATAAA
TAAAAAATGAATAAGCTACTTATCTCTGCTTTAATTTGCTTAATGATTGCTACTCCTAGT
GTGTTTTGCTAGGATGTTGAAAATAACATTTCTGAAGACATTAAAGTCTAAGACTTATTA
GCATACAATAAATGGAGATTCAACTATAAGAGAGTCTATCTTAATGAAGAAGAGCAGATC
TACAGATAGATTGTTTTCTTTGAAAATCTTGCTAGTGTTAACAAACACCCTTCTCATAAA
TCCTACAGTAAGGGTTTGAACCAGTTCTCTGATATGACTAAAGAAGAATTCAAACAAAGA
GTTTTGAATAAGAAGATTTCTAAAAAGGCTAGCAGTAATAAGGGTGGTAGAAATTTAGCT
GCTGATCCAGCTGTTTCCAACTTAGTCTTTCCCACCAATAATCTTCCTCTATCTGTTGAT
TGGAGAAAAAGAGGTGTCCTCAATCCTGTAAAAAATTAAGGTACTTGTGGTTCATGCTGG
ACTTTTGCAACTGCTGGCATCCTTGAGTCATTCAACTAAATTAAAAATAAATAGCTTCTT
AAGTTCTCTGAGCAACAACTTGTTGATTGTGTCAGCCTAGCTGGATATGATTCTGATGGT
TGTGATGGTGGTTTTTAAGAAGATGGTGTTAGATATGCAATTGAGTATGGTATTGTTTAA
TCTTACAAATACCCTTATGTTGGATATCAAGGTAGATGCAAAGTCACATCTCCCACTTCT
CGTTCTGTAGGTTTTTACCCTTAAAAGTTCCAACTTGTCAATAAAACTGAAGCTGACTTG
AAAGCTGCTTTAGTTTTCTCCCCTGTTTCAATCTCCGTCAATGCTGATACCTGGAAAGAA
TACTATGGTGGTGTTTTTGATGAATGTGGATATACTACCGAAGAAGATCTCAATCATGCT
GTCATCGCTGTAGGTTATGACCAAGAAGGTAACTGGATTGTTAGAAACAGTTGGTCTGCA
GCTTGGGGTGAAGATGGTTACATAAGATTAGCTCCTGGTAACACTTGTGGTATTTTGCTT
GATGGATTAATAGTTACTTAATGA

>TTHERM_00439250(gene)
ATGATACTCAAACATATCATCAATTAAATAAAATATTTACTAGAACGAACGGTAAGCTTT
AAATCTTGGATATTTTAGTCATAAAATTTATAAAAATTATAAAACAAAAAAACTAATAAA
TAAAAAATGAATAAGCTACTTATCTCTGCTTTAATTTGCTTAATGATTGCTACTCCTAGT
GTGTTTTGCTAGGATGTTGAAAATAACATTTCTGAAGACATTAAAGTCTAAGACTTATTA
GCATACAATAAATGGAGATTCAACTATAAGAGAGTCTATCTTAATGAAGAAGAGCAGATC
TACAGATAGATTGTTTTCTTTGAAAATCTTGCTAGTGTTAACAAACACCCTTCTCATAAA
TCCTACAGTAAGGGTTTGAACCAGTTCTCTGATATGACTAAAGAAGAATTCAAACAAAGA
GTTTTGAATAAGAAGATTTCTAAAAAGGCTAGCAGTAATAAGGGTGGTAGAAATTTAGCT
GCTGATCCAGCTGTTTCCAACTTAGTCTTTCCCACCAATAATCTTCCTCTATCTGTTGAT
TGGAGAAAAAGAGGTGTCCTCAATCCTGTAAAAAATTAAGGTACTTGTGGTTCATGCTGG
ACTTTTGCAACTGCTGGCATCCTTGAGTCATTCAACTAAATTAAAAATAAATAGCTTCTT
AAGTTCTCTGAGCAACAACTTGTTGATTGTGTCAGCCTAGCTGGATATGATTCTGATGGT
TGTGATGGTGGTTTTTAAGAAGATGGTGTTAGATATGCAATTGAGTATGGTATTGTTTAA
TCTTACAAATACCCTTATGTTGGATATCAAGGTAGATGCAAAGTCACATCTCCCACTTCT
CGTTCTGTAGGTTTTTACCCTTAAAAGTTCCAACTTGTCAATAAAACTGAAGCTGACTTG
AAAGCTGCTTTAGTTTTCTCCCCTGTTTCAATCTCCGTCAATGCTGATACCTGGAAAGAA
TACTATGGTGGTGTTTTTGATGAATGTGGATATACTACCGAAGAAGATCTCAATCATGCT
GTCATCGCTGTAGGTTATGACCAAGAAGGTAACTGGATTGTTAGAAACAGTTGGTCTGCA
GCTTGGGGTGAAGATGGTTACATAAGATTAGCTCCTGGTAACACTTGTGGTATTTTGCTT
GATGGATTAATAGTTACTTAATGA

>TTHERM_00439250(protein)
MILKHIINQIKYLLERTVSFKSWIFQSQNLQKLQNKKTNKQKMNKLLISALICLMIATPS
VFCQDVENNISEDIKVQDLLAYNKWRFNYKRVYLNEEEQIYRQIVFFENLASVNKHPSHK
SYSKGLNQFSDMTKEEFKQRVLNKKISKKASSNKGGRNLAADPAVSNLVFPTNNLPLSVD
WRKRGVLNPVKNQGTCGSCWTFATAGILESFNQIKNKQLLKFSEQQLVDCVSLAGYDSDG
CDGGFQEDGVRYAIEYGIVQSYKYPYVGYQGRCKVTSPTSRSVGFYPQKFQLVNKTEADL
KAALVFSPVSISVNADTWKEYYGGVFDECGYTTEEDLNHAVIAVGYDQEGNWIVRNSWSA
AWGEDGYIRLAPGNTCGILLDGLIVTQ