Identifiers and Description

Gene Model Identifier

TTHERM_00441760

Standard Name

DRH21 (DExD/H box RNA helicase 21)

Aliases

PreTt05578 | 50.m00147 | 3681.m00006

Description

DRH21 Pre-mRNA-splicing factor ATP-dependent RNA helicase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• helicase activity (IEA) | GO:0004386
• nucleic acid binding (IEA) | GO:0003676

Domains

• ( PF00008 ) EGF-like domain
• ( PF00020 ) TNFR/NGFR cysteine-rich region
• ( PF00270 ) DEAD/DEAH box helicase
• ( PF00271 ) Helicase conserved C-terminal domain
• ( PF00451 ) Scorpion short toxin, BmKK2
• ( PF01457 ) Leishmanolysin
• ( PF01480 ) PWI domain
• ( PF02420 ) Insect antifreeze protein repeat
• ( PF03128 ) CXCXC repeat
• ( PF03860 ) Domain of Unknown Function (DUF326)
• ( PF04408 ) Helicase associated domain (HA2), winged-helix
• ( PF05501 ) Domain of unknown function (DUF755)
• ( PF07717 ) Oligonucleotide/oligosaccharide-binding (OB)-fold
• ( PF07974 ) EGF-like domain
• ( PF07986 ) Tubulin binding cofactor C
• ( PF08758 ) Cadherin prodomain like
• ( PF08825 ) E2 binding domain
• ( TIGR00179 ) UDP-N-acetylenolpyruvoylglucosamine reductase
• ( TIGR01360 ) adenylate kinase
• ( TIGR01587 ) CRISPR-associated helicase Cas3
• ( TIGR01612 ) rhoptry protein
• ( TIGR01967 ) ATP-dependent helicase HrpA
• ( TIGR01970 ) ATP-dependent helicase HrpB

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_23171	0
	Description: None
WormBase	WBGene00003392	9.997093137033517e-262
	Description: locus:mog-4 Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4 status:Confirmed UniProt:O45244 protein_id:CAB03845.1
Tetrahymena borealis	EI9_12515.1	9.997093137033517e-262
	Description: RNA helicase (1067 aa)
DictyBase	DDB_G0285937	9.997093137033517e-262
	Description: dhx16 on chromosome: 4 position 3866187 to 3869507
Oxytricha	Contig3639.0.g11	9.997093137033517e-262
	Description: Oligonucleotide/oligosaccharide-binding (OB)-fold
SGD	YER013W	9.997093137033517e-262
	Description: PRP22 DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase, associates with lariat intermediates before the second catalytic step of splicing; mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes
WormBase	WBGene00004282	9.997093137033517e-262
	Description: locus:rab-30 status:Confirmed UniProt:Q9XWZ3 protein_id:CAA21489.1
Tetrahymena borealis	EI9_19041.1	9.997093137033517e-262
	Description: ABC transporter (5234 aa)

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00441760(coding)
ATGCAGTATAATATTGAAGATTTCATTAATGATAGCTTACATAAAATATTAGGGATTTCT
GATAGGAATATAGTCATGTATATAAAAGGAGTGACACAGTCAAGCAAATCAAAAGATTAG
CTTATTGATGGTCTCAAAGAGATGGAAATCTATCCTACAGATTCAAAGTCAAAAGTATTT
ATTGATGAATTGTATATGAAATATGTTTAGGGAACAAGTGAAACGACTTCTTAAAGAAGT
AGCTACGTTTAAGAAGAAATAAGGAAGGCAGCTTAAGTTCAAAAAAATAGTAATTATTAA
ATTATAGAGGAAGATCCACTCTCAATTACAGATAATGCATAAAAAAAAATAAAAACAAAT
GATGGAAACCCAGCTGCTAATAATTTAACTGATAAAGAGAAAGCTGAGCTAGCAAAAAAA
AAAGATATAGAAGAGCGCAATGAAATAGATAAGAAAATAAAAGAAAAGGATATGAAAAAA
AAGTAAGCTTTGAGTGGAGGAGCTTAGCTAGGAATGAATTTGACTGCTGAAGAAAAAGCT
GAGCTCATTCCACTTTTACAAAAAGAAGCTAGATAAAACTATGTCAAAGGCAGATTAGAT
AAATAAGTTGAATTATTAAAGAGAATGATTGAATATGATGAATTTCTAATTAAAAATCAT
AAAGTTACAGACGAAGAAATCAAGAGTTATGAAGAAAAAAAGAAAATTTTAGAAGCTGTA
TAAAGTACAGACTTAACATAAAAAGAAGCAGATATATATGAAATGCCTTAGCTTTTTGAA
GATGATGAAGGAAAATATGATAGGAGAAAAGCTGCTAATGCTCAAACTTAAAAATATAAA
GATGTTCCTTATGAACCTAGTGAGCATGAAAAATGGGAGAGGGAATAGACTTAACGAAAC
TAAGTAAAATTTGGAACTAACACTTTAACAAAGCAGTAATAAGAAGAACAAAACTATAAA
ATATTAATGGAAAATGAAATTTAATTTATCAAGAGTGATATAATTAAAGAGCAATTGCTT
AAATAAAAACAAATGCTTGATAGTATGAAGAGTAAAAAAAAATCTAAAAAGAGTTCTAAG
AAAGACAAGAAAAAATCTAAGAAGAAAAGCAAAGATTCTTCAGATTCATCTGAAGACTCA
GAAGGGTCATCTAGTGGTGATGAGACACAGGACGATAATATTTACATCAAGAATGATTAA
TAACCTTAAAACTAATAAGAGTTACTTTAATTAAGTGAAAGGGAGAAAATGAAGAGAGTT
CGCCAATCACTACCTATTTATAAATATAGAGAAGAACTTCTTACTTTGATAAGAGATAAT
AGAGTTATTGTCATGGTTGGTGAGACTGGTTCAGGTAAAACGACACAAGTACCTTAGTAT
TTGCACGAAGTTGGATACACAAGCACAGGTAGAATAGGTTGTACTCAGCCTAGAAGAGTA
GCAGCTATGAGTGTAGCAGCTCGTGTTTCAGAAGAAATGGGAACAAAATTAGGTCATGAA
GTTGGTTACTCTATTCGTTTTGAAGACTGTACAAGCGATAAAACTGTTATTAAATATATG
ACAGATGGTATGCTACTTCGTGAACTGATGATGGAGCCTGATTTGGCATCTTACTCTGTT
ATGATTGTTGATGAAGCACATGAACGTACTCTTCACACAGATATTTTGTTGTCTATTATT
AAAGATCTTTCTCGTGCTAGAGATGATTTAAAAGTTATTATTTCATCAGCTACTATTGAT
GCTTAAAGATTTTCTGAATATTTTGATAACTGTCCAATTATTAAAATTCCAGGAAGGCGT
TTTTAGGTTGATATTTACTATACCAAGGCACCCGAATCTGATTATATTTAAGCTGCTGTT
CTGACTGTTCTTTAAATTCATGTCACACAGCCGAAAGGAGATATATTGGTTTTTCTAACT
GGTTAAGAAGAAATAGAAGCTGCAGAAGAGATGCTAACTGCAAGAACTCGTGGTCTAGGA
AATAAGATAGGAGAGCTTTTAATATGCCCTATTTACTCTTCTTTACCTTCTGATATGCAA
GCAAAAATTTTTGAACCTACTCCTGCTGGAGCAAGAAAAGTTGTACTTTCAACAAATATA
GCAGAAACATCTATCACTATTGATAATATTATATACGTTATAGATACTGGATTTGCTAAA
TAAACTTCTTATAACCCCCGTACAGGAATGGAGAGTTTGATAGTCACTCCTATTTCCAAA
GCATCTGCAGATTAAAGAGCAGGACGTGCTGGTAGAGTAGCACCAGGTAAATGCTTTCGT
ATGTATACCAAGTGGAGTTTCTTAAATGAACTTGATTAAAATACAATACCAGAAATTTAA
CGTACTAATCTTGGTTCTGTTGTGTTAATGTTAAAAAGTATGGGTATAAATAATTTAGTT
AATTTCGATTTTATGGACTCTCCTCCTCCTGAAATGATTGTCAAATCTCTTGAATAATTA
TATGCATTGGGAGCAATAAATGATGAGGGTGATCTTACAAAGCTGGGCAGGAGAATGGCT
GAGTTTCCTTTAGATCCTTTCTTGAGTAAAATGTTAGTTTAATCTGAGCATTATAAATGT
GTGGATCAGATTATTACTATTTGTGCTATGCTTTCAGTAGGAAATACCATATTTTACAGA
CCAAATGATAAAGAGAAAAAAATACATGCAGACAATTCGAGAAAAGCATTCTTCCGTCCA
GGTGGTGACCATCTAGCCCTCCTAAATGTTTACAACACATGGGCTGATAATGGATTTTCA
TAAAATTGGTGCTTTGAAAATTTTATTTAAATAAGATCAATGAGACGTGCAAGAGATGTT
AGAGAATAATTAATATTATTATGTGAGCGTGTTGAAATAGATGTTAAAGACCCAAGTTTA
AGTATATTTGAAGATGAAATGAATACAAATATTTGCAAATGTATTTGTAGTGGGTTCTTT
TATAATGCAGCTAAAACAAATTTAAACGGAACATACAAGACGTTAAAAAATGGGCATTCA
ATAACCATCCACCCAAGCTCCTTGATGTTTGATATCAAGCCTGAATGGATTGTTTACAAT
GAATTAGTTTTCACTTCAAAAGAATATGTTCGTAATGTAATTGAAGTAAAAGGAGAATGG
TTAATTGAAATAGCTCCTCACCTTTATAAAGAAAAAGATTTACTTGGTGATAAACGTAAA
ATGCCTAAAAACACAGGCACTTCTGATAGTAGAAATTGA

>TTHERM_00441760(gene)
ATGCAGTATAATATTGAAGATTTCATTAATGATAGCTTACATAAAATATTAGGGATTTCT
GATAGGAATATAGTCATGTATATAAAAGGAGTGACACAGTCAAGCAAATCAAAAGATTAG
CTTATTGATGGTCTCAAAGAGATGGAAATCTATCCTACAGATTCAAAGTCAAAAGTATTT
ATTGATGAATTGTATATGAAATATGTTTAGGGAACAAGTGAAACGACTTCTTAAAGAAGT
AGCTACGTTTAAGAAGAAATAAGGAAGGCAGCTTAAGTTCAAAAAAATAGTAATTATTAA
ATTATAGAGGAAGATCCACTCTCAATTACAGATAATGCATAAAAAAAAATAAAAACAAAT
GATGGAAACCCAGCTGCTAATAATTTAACTGATAAAGAGAAAGCTGAGCTAGCAAAAAAA
AAAGATATAGAAGAGCGCAATGAAATAGATAAGAAAATAAAAGAAAAGGATATGAAAAAA
AAGTAAGCTTTGAGTGGAGGAGCTTAGCTAGGAATGAATTTGACTGCTGAAGAAAAAGCT
GAGCTCATTCCACTTTTACAAAAAGAAGCTAGATAAAACTATGTCAAAGGCAGATTAGAT
AAATAAGTTGAATTATTAAAGAGAATGATTGAATATGATGAATTTCTAATTAAAAATCAT
AAAGTTACAGACGAAGAAATCAAGAGTTATGAAGAAAAAAAGAAAATTTTAGAAGCTGTA
TAAAGTACAGACTTAACATAAAAAGAAGCAGATATATATGAAATGCCTTAGCTTTTTGAA
GATGATGAAGGAAAATATGATAGGAGAAAAGCTGCTAATGCTCAAACTTAAAAATATAAA
GATGTTCCTTATGAACCTAGTGAGCATGAAAAATGGGAGAGGGAATAGACTTAACGAAAC
TAAGTAAAATTTGGAACTAACACTTTAACAAAGCAGTAATAAGAAGAACAAAACTATAAA
ATATTAATGGAAAATGAAATTTAATTTATCAAGAGTGATATAATTAAAGAGCAATTGCTT
AAATAAAAACAAATGCTTGATAGTATGAAGAGTAAAAAAAAATCTAAAAAGAGTTCTAAG
AAAGACAAGAAAAAATCTAAGAAGAAAAGCAAAGATTCTTCAGATTCATCTGAAGACTCA
GAAGGGTCATCTAGTGGTGATGAGACACAGGACGATAATATTTACATCAAGAATGATTAA
TAACCTTAAAACTAATAAGAGTTACTTTAATTAAGTGAAAGGGAGAAAATGAAGAGAGTT
CGCCAATCACTACCTATTTATAAATATAGAGAAGAACTTCTTACTTTGATAAGAGATAAT
AGAGTTATTGTCATGGTTGGTGAGACTGGTTCAGGTAAAACGACACAAGTACCTTAGTAT
TTGCACGAAGTTGGATACACAAGCACAGGTAGAATAGGTTGTACTCAGCCTAGAAGAGTA
GCAGCTATGAGTGTAGCAGCTCGTGTTTCAGAAGAAATGGGAACAAAATTAGGTCATGAA
GTTGGTTACTCTATTCGTTTTGAAGACTGTACAAGCGATAAAACTGTTATTAAATATATG
ACAGATGGTATGCTACTTCGTGAACTGATGATGGAGCCTGATTTGGCATCTTACTCTGTT
ATGATTGTTGATGAAGCACATGAACGTACTCTTCACACAGATATTTTGTTGTCTATTATT
AAAGATCTTTCTCGTGCTAGAGATGATTTAAAAGTTATTATTTCATCAGCTACTATTGAT
GCTTAAAGATTTTCTGAATATTTTGATAACTGTCCAATTATTAAAATTCCAGGAAGGCGT
TTTTAGGTTGATATTTACTATACCAAGGCACCCGAATCTGATTATATTTAAGCTGCTGTT
CTGACTGTTCTTTAAATTCATGTCACACAGCCGAAAGGAGATATATTGGTTTTTCTAACT
GGTTAAGAAGAAATAGAAGCTGCAGAAGAGATGCTAACTGCAAGAACTCGTGGTCTAGGA
AATAAGATAGGAGAGCTTTTAATATGCCCTATTTACTCTTCTTTACCTTCTGATATGCAA
GCAAAAATTTTTGAACCTACTCCTGCTGGAGCAAGAAAAGTTGTACTTTCAACAAATATA
GCAGAAACATCTATCACTATTGATAATATTATATACGTTATAGATACTGGATTTGCTAAA
TAAACTTCTTATAACCCCCGTACAGGAATGGAGAGTTTGATAGTCACTCCTATTTCCAAA
GCATCTGCAGATTAAAGAGCAGGACGTGCTGGTAGAGTAGCACCAGGTAAATGCTTTCGT
ATGTATACCAAGTGGAGTTTCTTAAATGAACTTGATTAAAATACAATACCAGAAATTTAA
CGTACTAATCTTGGTTCTGTTGTGTTAATGTTAAAAAGTATGGGTATAAATAATTTAGTT
AATTTCGATTTTATGGACTCTCCTCCTCCTGAAATGATTGTCAAATCTCTTGAATAATTA
TATGCATTGGGAGCAATAAATGATGAGGGTGATCTTACAAAGCTGGGCAGGAGAATGGCT
GAGTTTCCTTTAGATCCTTTCTTGAGTAAAATGTTAGTTTAATCTGAGCATTATAAATGT
GTGGATCAGATTATTACTATTTGTGCTATGCTTTCAGTAGGAAATACCATATTTTACAGA
CCAAATGATAAAGAGAAAAAAATACATGCAGACAATTCGAGAAAAGCATTCTTCCGTCCA
GGTGGTGACCATCTAGCCCTCCTAAATGTTTACAACACATGGGCTGATAATGGATTTTCA
TAAAATTGGTGCTTTGAAAATTTTATTTAAATAAGATCAATGAGACGTGCAAGAGATGTT
AGAGAATAATTAATATTATTATGTGAGCGTGTTGAAATAGATGTTAAAGACCCAAGTTTA
AGTATATTTGAAGATGAAATGAATACAAATATTTGCAAATGTATTTGTAGTGGGTTCTTT
TATAATGCAGCTAAAACAAATTTAAACGGAACATACAAGACGTTAAAAAATGGGCATTCA
ATAACCATCCACCCAAGCTCCTTGATGTTTGATATCAAGCCTGAATGGATTGTTTACAAT
GAATTAGTTTTCACTTCAAAAGAATATGTTCGTAATGTAATTGAAGTAAAAGGAGAATGG
TTAATTGAAATAGCTCCTCACCTTTATAAAGAAAAAGATTTACTTGGTGATAAACGTAAA
ATGCCTAAAAACACAGGCACTTCTGATAGTAGAAATTGA

>TTHERM_00441760(protein)
MQYNIEDFINDSLHKILGISDRNIVMYIKGVTQSSKSKDQLIDGLKEMEIYPTDSKSKVF
IDELYMKYVQGTSETTSQRSSYVQEEIRKAAQVQKNSNYQIIEEDPLSITDNAQKKIKTN
DGNPAANNLTDKEKAELAKKKDIEERNEIDKKIKEKDMKKKQALSGGAQLGMNLTAEEKA
ELIPLLQKEARQNYVKGRLDKQVELLKRMIEYDEFLIKNHKVTDEEIKSYEEKKKILEAV
QSTDLTQKEADIYEMPQLFEDDEGKYDRRKAANAQTQKYKDVPYEPSEHEKWEREQTQRN
QVKFGTNTLTKQQQEEQNYKILMENEIQFIKSDIIKEQLLKQKQMLDSMKSKKKSKKSSK
KDKKKSKKKSKDSSDSSEDSEGSSSGDETQDDNIYIKNDQQPQNQQELLQLSEREKMKRV
RQSLPIYKYREELLTLIRDNRVIVMVGETGSGKTTQVPQYLHEVGYTSTGRIGCTQPRRV
AAMSVAARVSEEMGTKLGHEVGYSIRFEDCTSDKTVIKYMTDGMLLRELMMEPDLASYSV
MIVDEAHERTLHTDILLSIIKDLSRARDDLKVIISSATIDAQRFSEYFDNCPIIKIPGRR
FQVDIYYTKAPESDYIQAAVLTVLQIHVTQPKGDILVFLTGQEEIEAAEEMLTARTRGLG
NKIGELLICPIYSSLPSDMQAKIFEPTPAGARKVVLSTNIAETSITIDNIIYVIDTGFAK
QTSYNPRTGMESLIVTPISKASADQRAGRAGRVAPGKCFRMYTKWSFLNELDQNTIPEIQ
RTNLGSVVLMLKSMGINNLVNFDFMDSPPPEMIVKSLEQLYALGAINDEGDLTKLGRRMA
EFPLDPFLSKMLVQSEHYKCVDQIITICAMLSVGNTIFYRPNDKEKKIHADNSRKAFFRP
GGDHLALLNVYNTWADNGFSQNWCFENFIQIRSMRRARDVREQLILLCERVEIDVKDPSL
SIFEDEMNTNICKCICSGFFYNAAKTNLNGTYKTLKNGHSITIHPSSLMFDIKPEWIVYN
ELVFTSKEYVRNVIEVKGEWLIEIAPHLYKEKDLLGDKRKMPKNTGTSDSRN