Identifiers and Description

Gene Model Identifier

TTHERM_00442300

Standard Name

ASF1 (Anti-Silencing Factor 1)

Aliases

PreTt05630 | 50.m00199 | 3681.m00058

Description

ASF1 histone chaperone asf1; Anti-silencing protein ASF1-like containing protein; mediates nuclear transport of newly synthesized histones H3 and H4; Histone chaperone ASF1-like

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Molecular Function

Domains

  • ( PF04729 ) ASF1 like histone chaperone

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:37024975: Nabeel-Shah S, Garg J, Ashraf K, Jeyapala R, Lee H, Petrova A, Burns JD, Pu S, Zhang Z, Greenblatt JF, Pearlman RE, Lambert JP, Fillingham J (2023) Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation. Epigenetics & chromatin 16:10
  2. Ref:34086947: Nabeel-Shah S, Garg J, Saettone A, Ashraf K, Lee H, Wahab S, Ahmed N, Fine J, Derynck J, Pu S, Ponce M, Marcon E, Zhang Z, Greenblatt JF, Pearlman RE, Lambert JP, Fillingham J (2021) Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila. Nucleic acids research ( ):
  3. Ref:28621664: Akematsu T, Fukuda Y, Garg J, Fillingham JS, Pearlman RE, Loidl J (2017) Post-meiotic DNA double-strand breaks occur in Tetrahymena, and require Topoisomerase II and Spo11. eLife 6( ):
  4. Ref:24120531: Garg J, Lambert JP, Karsou A, Marquez S, Nabeel-Shah S, Bertucci V, Retnasothie DV, Radovani E, Pawson T, Gingras AC, Pearlman RE, Fillingham JS (2013) Conserved Asf1-importin ? physical interaction in growth and sexual development in the ciliate Tetrahymena thermophila. Journal of proteomics 94( ):311-26

Sequences 

>TTHERM_00442300(coding)
ATGGCCTTAGTCAACATCTAAAACATCCAATTTCATAACAACCCTTGCCCTTTTTTGAGT
CCCTTTAAACTTGACGTAACCTTCGAATGTATCAAACCTATACCTGATGACATTGAATGG
TAATTAATTTATATTGGTTCTGCTAAAGATGAGAAATACGATTAAGTCCTTGATAAATTC
AGTATTGGGTCATTAGATTAAGGAGTGCTTTAATTTACCATTGAAACAAATCCACCTGAT
CACACTAAGATTCCAAACAAAGATGATTTACTTGGTGTAACTGCTATAATTCTAACTGTT
TCATACCACAATCAGGAGTTTTTCCGTGTTGGATACTATGTCTACAATCAATACAATGAT
CAGGAACTTATTATTAATGATCCTCCTTAAATTCTAATTGATAAGGTTGAGCGTAGTATC
CTTGATAAATAGCCTCGTATCACTCATTTCAACATAAAATGGGGTACTGAGGATGAAAAT
AAAGAAACTGACCCTAATACTTTAGCTATCCTCTAACAGTAATTAGCTTAAAATGGAACC
ATTCCTAATTAACTCATGCAAGAAATGCAATAAGTGAATAGCTAAATGCAATCTTTCTTA
CCTGATCCTTTTTCTAAGTCATCAGGAATACTCTAAGAGTTAACAACATAAGGATAGACT
AACAGCACAAATAGTTTCATGTTTGGTTAAGGGCTAGACATACCTTAAAATAATGCATTC
CAACCTACAAATGTATTCAGTTCTAATCCTTACTGA



>TTHERM_00442300(gene)
TATATAGATATGAGCCAAATCAAAAAAATTTTAATGCCTGATATTTAATATTTTCTCCGG
TAATTAAGTAGGCGTTGAATATATATTAATGCAGTTTTCCTATGAAAAAATATATATTTA
AGATTGTGTTAGATATTATTATTTTTTATTTTTCGAAAAAAAAATTAAAAAAACAAATTT
TAATAATTCAAGAAAAAGTAAGAAAAAAATCTTGCTCATTTTCAGAAAGAAAAAAGGTTA
GAAAAAGTTTATCTTCACACAAAGCTTCACAGCTCATCAAAGAACTCTATTTTTATTAAT
TTATAGGAAGCAACTTCGTTTCGCGTTAGAATAAAATAAATATTAAACAAGAAAAAAATC
CAAAAAGTACGCATTTATCTACCTCAAATAAGCAAAATGGCCTTAGTCAACATCTAAAAC
ATCCAATTTCATAACAACCCTTGCCCTTTTTTGAGTCCCTTTAAACTTGACGTAACCTTC
GAATGTATCAAACCTATACCTGATGACATTGAATGGTAATTAATTTATATTGGTTCTGCT
AAAGATGAGAAATACGATTAAGTCCTTGATAAATTCAGTATTGGGTCATTAGATTAAGGA
GTGCTTTAATTTACCATTGAAACAAATCCACCTGATCACACTAAGATTCCAAACAAAGAT
GATTTACTTGGTGTAACTGCTATAATTCTAACTGTTTCATACCACAATCAGGAGTTTTTC
CGTGTTGGATACTATGTCTACAATCAATACAATGATCAGGAACTTATTATTAATGATCCT
CCTTAAATTCTAATTGATAAGGTTGAGCGTAGTATCCTTGATAAATAGCCTCGTATCACT
CATTTCAACATAAAATGGGGTACTGAGGATGAAAATAAAGAAACTGACCCTAATACTTTA
GCTATCCTCTAACAGTAATTAGCTTAAAATGGAACCATTCCTAATTAACTCATGCAAGAA
ATGCAATAAGTGAATAGCTAAATGCAATCTTTCTTACCTGATCCTTTTTCTAAGTCATCA
GGAATACTCTAAGAGTTAACAACATAAGGATAGACTAACAGCACAAATAGTTTCATGTTT
GGTTAAGGGCTAGACATACCTTAAAATAATGCATTCCAACCTACAAATGTATTCAGTTCT
AATCCTTACTGAAAATGGAGAACATTGTAAATAAAAATAAACACATAAATTCCTTTTCTT
AATACAAACAAATTTCTACATTAATAGCTATACTTAAAGGATAATTTAGCAACAAATATT
ATAAAATAAAAGTAATGAAATTTAAAACAATTACTCATAAATAATATAAATGCATGAAAA
TTGATCACTGATCTTATACAATAAATAGTATAGGCACTTTGAGCAAAATTTTAAGATCTA
ATAGGTTGGTTGGTTTGTAAGTAAGAAAGTAGCCACATATTTTTGAAAATTATAAAAAAA
ATAAATAAAATTTAGTATTAATTAGCATGAATGACTGATTATCTTGATAGAGTTTTGAAT
TGCATCAAAAAAAAACATTATGAGATAATAATTACATAAATAAAATAACAATCAATGCAT
CTTAAAATTATTCATCTTCAAATATATAAATAAATAAATCAAT



>TTHERM_00442300(protein)
MALVNIQNIQFHNNPCPFLSPFKLDVTFECIKPIPDDIEWQLIYIGSAKDEKYDQVLDKF
SIGSLDQGVLQFTIETNPPDHTKIPNKDDLLGVTAIILTVSYHNQEFFRVGYYVYNQYND
QELIINDPPQILIDKVERSILDKQPRITHFNIKWGTEDENKETDPNTLAILQQQLAQNGT
IPNQLMQEMQQVNSQMQSFLPDPFSKSSGILQELTTQGQTNSTNSFMFGQGLDIPQNNAF
QPTNVFSSNPY