Identifiers and Description

Gene Model Identifier

TTHERM_00446090

Standard Name

RPN3 (26S proteasome regulatory subunit N3)

Aliases

PreTt03878 | 51.m00244 | 3704.m00099

Description

RPN3 26S proteasome non-ATPase regulatory subunit 3 putative; PCI domain containing protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• proteasome complex (IEA) | GO:0000502
• proteasome regulatory particle (ISS) | GO:0005838

Molecular Function

• enzyme regulator activity (IEA) | GO:0030234

Biological Process

• regulation of protein catabolic process (IEA) | GO:0042176

Domains

• ( PF00515 ) Tetratricopeptide repeat
• ( PF01399 ) PCI domain
• ( PF07719 ) Tetratricopeptide repeat
• ( PF08375 ) Proteasome regulatory subunit C-terminal
• ( TIGR00166 ) ribosomal protein S6

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_10841.1	9.997093137033517e-262
	Description: PCI domain-containing protein (484 aa)
Tetrahymena borealis	EI9_21220.1	9.997093137033517e-262
	Description: hypothetical protein (301 aa)
Oxytricha	Contig16126.0.g91	2.0005752503420762e-105
	Description: PCI domain
DictyBase	DDB_G0288621	3.9981372112117256e-92
	Description: psmD3 on chromosome: 5 position 1750413 to 1752480
WormBase	WBGene00004460	6.000161128365848e-68
	Description: locus:rpn-3 26S proteasome non-ATPase regulatory subunit 3 status:Confirmed UniProt:Q04908 protein_id:CCD66158.1
WormBase	WBGene00011631	6.000161128365848e-68
	Description: status:Confirmed UniProt:Q94013 protein_id:CAB02307.2
SGD	YER021W	2.000597631390999e-64
	Description: RPN3 Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control
Stentor Coeruleus	SteCoe_22558	2.6786369618080778e-33
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:21637855: Xiong J, Yuan D, Fillingham JS, Garg J, Lu X, Chang Y, Liu Y, Fu C, Pearlman RE, Miao W (2011) Gene network landscape of the ciliate Tetrahymena thermophila. PloS one 6(5):e20124

Sequences

>TTHERM_00446090(coding)
ATGTCATAAGCTAAAGACGATAAAAATAACAAAGATAATTAAGCCAAAAAGGTTGAAAAG
AAGGAAGAAGTTGTTAAGAAACCTGTTACCCTTTTAGAAGAACTCAGAAACTAGGTTTTA
ACAATTGAAAAAGCTATAACTTAAAGCGATTTAAAGACTGTTTAGAAGACATGCAAAGGT
ATGAGACGCTTCAAAAAATATTTAAAATCTCACCACTTTGCTAAAATTTGGGCTGCTATC
TTCCCAAATGAAACTGAATATAACTTTGAAAGCTTTGAAGATTTCGATAAAACATTTGAA
GAGAATTTCGATATTTCCAAGAAAAAAGTTTAAAAAATTTCAAAGGCTCCTGAATTTGAT
TTCTTTTTCAAAATTCTCCTTTTATGCTACTTCCTTCAAATAAATAAAGTTGATCAAGCT
TATGATTTAGCTGGAAAGCTGTTTAACAGAGTTTCTGAAGTTAATAAAAAGCATTTTGAA
TAGCTGAGTGCCTTTGTTTATTTCTATTATGCACGTACTCGTGAAATTAAAAACCAAATT
ATTGAAATTAGGGAAGAACTATTCGAGGCTTATAGATTAGCATGTATCAAGCATAATGAT
TTAGCTTAAGCTACTTTAATTAATGCTATTTTGAGAAACTATTTGCACTACAATCACTAT
GAAGCTGCTTAACATTTTGTTTCTAAAATTACTTTCCCTGAAAATGTATCAAACAACGAA
CTAATTCGTTTCCTTTACTACACTGGTAGAATAAAAGCTGTTCAAGTAGAATACTCTGAA
GCTTTCAATTACCTTAATTAAGCTCTCAAAAAGTCTCCTGATAACTCTGCTTTAGGATTC
CGTATTGAAGCATAAAAACTTGCTATTATAGTAGAATTTTTAATGGGTAATATTCCTAGT
AGAGATATTTTTACAAAGTAAGAGTTCTGGAAACCTCTTTATCCTTACTATAAGTTAGTT
TAAAGTGTATTGAGAGGTAATTTGCTTGACTTTAACAAAGTTGTTGCTTAATATGCAAAC
TTGTTCATAAAAGATAAAAATTTTTCTTTAATTCAAAGGTTATAGCAAACAGTTATTAAA
ACTGGATTAAGAAAAATCAATTTATCCTATAGCAGAATTTCATTTACTGATATTGCATAA
AAATTAGACTTGAAAAAAAATAGTGATGTTGAATTCATCGTAGCAAAAGCCATTAGAGAT
GGTATCCTTAATGCAAAGATTGACCATGAAAATTAGTATATAGTTATTAAGCAAGAAAAC
GATATCTATAGTACTAATTAACCTTAAGATGCTTTCGCTAAGAGAATTTCATATTGTCTT
AACCTCCACAACTCTGCTACTAAAGCTCTTTAGTATCCTGATACAAACTACCAATATTAG
AATAAAAGCGATGATGAAAATGATGATGATGAGGATATTGATATTTATAAAATTATGGAA
GAAGACAGTTGA

>TTHERM_00446090(gene)
ATGTCATAAGCTAAAGACGATAAAAATAACAAAGATAATTAAGCCAAAAAGGTTGAAAAG
AAGGAAGAAGTTGTTAAGAAACCTGTTACCCTTTTAGAAGGTAATTTCAAAGAAGAAATG
AAAATGTTTTATATTGATTTAAATAAATTCTTACAAATTTTGATGATTTTAATCATGCAA
TTTTTGATGTAAAAACGACATTAATCATTTATTTAAATCAATAAAATGCATAAAAATTAA
TTTTTTTATTTTATTTAATGACTTATCTTAAAATCACATAGAACTCAGAAACTAGGTTTT
AACAATTGAAAAAGCTATAACTTAAAGCGATTTAAAGACTGTTTAGAAGACATGCAAAGG
TATGAGACGCTTCAAAAAATATTTAAAATCTCACCACTTTGCTAAAATTTGGGCTGCTAT
CTTCCCAAATGAAACTGAATATAACTTTGAAAGCTTTGAAGATTTCGATAAAACATTTGA
AGAGAATTTCGATATTTCCAAGAAAAAAGTTTAAAAAATTTCAAAGGCTCCTGAATTTGA
TTTCTTTTTCAAAATTCTCCTTTTATGCTACTTCCTTCAAATAAATAAAGTTGATCAAGT
ATGGTTTTTTTCTTCAAAAATTATGACGAATACAATTTATATACATTCAATAAATACATG
AGTATTCAAGTGACAAATACTATAAGCTTTTAACATATATTTATTATATAATATGTTTAA
TTATTATTATGTTTTGGGATGATTTTTCAATCTAAATTATAAATAAATTATTTAATAGGC
TTATGATTTAGCTGGAAAGCTGTTTAACAGAGTTTCTGAAGTTAATAAAAAGCATTTTGA
ATAGCTGAGTGCCTTTGTTTATTTCTATTATGCACGTACTCGTGAAATTAAAAACCAAAT
TATTGAAATTAGGGAGTAATAATTAATATGTTATGATAGCATTTTAGAATTTTAAAATGC
TTCTAGATTTTATTTGTAATTAAACATGTTTTTAATTAAAAAAGAGAACTATTCGAGGCT
TATAGATTAGCATGTATCAAGCATAATGATTTAGCTTAAGTAAATTCGATTTGAATAATG
TTTGATTCTTTAATAAGTTATCTAATTATATTATAAAAGGCTACTTTAATTAATGCTATT
TTGAGAAACTATTTGCACTACAATCACTATGAAGCTGCTTAACATTTTGTTTCTAAAATT
ACTTTCCCTGAAAATGTATCAAACAACGAACTAATTCGTTTCCTTTACTACACTGGTAGA
ATAAAAGCTGTTCAAGTAGAATACTCTGAAGCTTTCAATTACCTTAATTAAGCTCTCAAA
AAGTCTCCTGATAACTCTGCTTTAGGATTCCGTATTGAAGCATAAAAACTTGCTATTATA
GTAGAATTTTTAATGGTAATTTAGTTCTTAAAAATAACAAAATTTTACCTGAAATATTTT
TAAATAAAAGGGTAATATTCCTAGTAGAGATATTTTTACAAAGTAAGAGTTCTGGAAACC
TCTTTATCCTTACTATAAGTTAGTTTAAAGTGTATTGAGAGGTAATTTGCTTGACTTTAA
CAAAGTTGTTGCTTAATATGCAAACTTGTTCATAAAAGATAAAAATTTTTCTTTAATTCA
AAGGTAAAAAATCAATAAAATGAAATGCAAAAATAAAATTTTTTTAATTATTTTAAATAT
AGGTTATAGCAAACAGTTATTAAAACTGGATTAAGAAAAATCAATTTATCCTATAGCAGA
ATTTCATTTACTGATATTGCATAAAAATTAGACTTGAAAAAAAATAGTGATGTTGAATTC
ATCGTAGCAAAAGCCATTAGAGATGGTATCCTTAATGCAAAGATTGACCATGAAAATTAG
TATATAGTTATTAAGGTAATTTCTTAAATAATCTTTTAAAAAAAGCATAAAATTTTTAAT
TTAAAATTATAAACTAATAGCAAGAAAACGATATCTATAGTACTAATTAACCTTAAGATG
CTTTCGCTAAGAGAATTTCATATTGTCTTAACCTCCACAACTCTGCTACTAAAGTAATTT
AAACAAATTCTATAAATAAAATTAAAAATTATAAATGTTTTTTAATACTTAATAGGCTCT
TTAGTATCCTGATACAAACTACCAATATTAGAATAAAAGCGATGATGAAAATGATGATGA
TGAGGATATTGATATTTATAAAATTATGGAAGAAGACAGTTGA

>TTHERM_00446090(protein)
MSQAKDDKNNKDNQAKKVEKKEEVVKKPVTLLEELRNQVLTIEKAITQSDLKTVQKTCKG
MRRFKKYLKSHHFAKIWAAIFPNETEYNFESFEDFDKTFEENFDISKKKVQKISKAPEFD
FFFKILLLCYFLQINKVDQAYDLAGKLFNRVSEVNKKHFEQLSAFVYFYYARTREIKNQI
IEIREELFEAYRLACIKHNDLAQATLINAILRNYLHYNHYEAAQHFVSKITFPENVSNNE
LIRFLYYTGRIKAVQVEYSEAFNYLNQALKKSPDNSALGFRIEAQKLAIIVEFLMGNIPS
RDIFTKQEFWKPLYPYYKLVQSVLRGNLLDFNKVVAQYANLFIKDKNFSLIQRLQQTVIK
TGLRKINLSYSRISFTDIAQKLDLKKNSDVEFIVAKAIRDGILNAKIDHENQYIVIKQEN
DIYSTNQPQDAFAKRISYCLNLHNSATKALQYPDTNYQYQNKSDDENDDDEDIDIYKIME
EDS