Identifiers and Description

Gene Model Identifier

TTHERM_00449140

Standard Name

Brop-2 (Bromodomain containing protein 2)

Aliases

PreTt15432 | 52.m00210 | 3811.m00967

Description

Brop-2 bromodomain protein; Bromodomain

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• subrhabdomeral cisterna (IEA) | GO:0016029

Molecular Function

• 17alpha-hydroxyprogesterone binding (IEA) | GO:1903880
• 2-keto-3-deoxy-L-rhamnonate aldolase activity (IEA) | GO:0106099
• acylglycerone-phosphate reductase (NADP+) activity (IEA) | GO:0000140
• ferric enterobactin:proton symporter activity (IEA) | GO:0015345
• lanosterol synthase activity (IEA) | GO:0000250
• mitochondrial single subunit type RNA polymerase activity (IEA) | GO:0001065
• obsolete cation:cation antiporter activity (IEA) | GO:0015491
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• obsolete zinc, iron permease activity (IEA) | GO:0015342
• siderophore-iron transmembrane transporter activity (IEA) | GO:0015343
• type 4 neuropeptide Y receptor binding (IEA) | GO:0031844

Biological Process

• cellular response to homocysteine (IEA) | GO:1905375
• coenzyme A biosynthetic process (IEA) | GO:0015937
• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• imaginal disc eversion (IEA) | GO:0007561
• inactivation of recombination (HML) (IEA) | GO:0007537
• induction of apoptosis by extracellular signals (IEA) | GO:0008624
• inner ear receptor cell differentiation (IEA) | GO:0060113
• lung connective tissue development (IEA) | GO:0060427
• lung epithelium development (IEA) | GO:0060428
• lung saccule development (IEA) | GO:0060430
• negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (IEA) | GO:1902647
• negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902642
• negative regulation of cellular glucuronidation (IEA) | GO:2001030
• negative regulation of glutamate secretion (IEA) | GO:0014050
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• negative regulation of postsynaptic membrane organization (IEA) | GO:1901627
• negative regulation of vascular associated smooth muscle cell apoptotic process (IEA) | GO:1905460
• nonmotile primary cilium assembly (IEA) | GO:0035058
• obsolete age dependent accumulation of genetic damage (IEA) | GO:0007570
• obsolete aging (IEA) | GO:0007568
• obsolete extracellular carbohydrate transport (IEA) | GO:0006859
• obsolete maintenance of dosage compensation (IEA) | GO:0007551
• obsolete mRNA endonucleolytic cleavage involved in unfolded protein response (IEA) | GO:0070055
• obsolete positive regulation of histone H3-K4 trimethylation (IEA) | GO:1905437
• obsolete regulation of histone H3-K27 methylation (IEA) | GO:0061085
• ommochrome biosynthetic process (IEA) | GO:0006727
• plant-type cell wall modification (IEA) | GO:0009827
• positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
• positive regulation of dendrite extension (IEA) | GO:1903861
• positive regulation of double-strand break repair via nonhomologous end joining (IEA) | GO:2001034
• positive regulation of oxidative phosphorylation (IEA) | GO:1903862
• positive regulation of phospholipid translocation (IEA) | GO:0061092
• positive regulation of vascular associated smooth muscle cell apoptotic process (IEA) | GO:1905461
• primary lung bud formation (IEA) | GO:0060431
• propan-2-ol biosynthetic process (IEA) | GO:1902640
• protein localization to old growing cell tip (IEA) | GO:1903858
• pyrimidine nucleotide salvage (IEA) | GO:0032262
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (IEA) | GO:1902646
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
• regulation of cytokinin dehydrogenase activity (IEA) | GO:1903856
• regulation of ecdysteroid secretion (IEA) | GO:0007555
• regulation of gastric motility (IEA) | GO:1905333
• regulation of phosphorus utilization (IEA) | GO:0006795
• regulation of plant epidermal cell differentiation (IEA) | GO:1903888
• regulation of RNA binding transcription factor activity (IEA) | GO:1905255
• rhamnogalacturonan II biosynthetic process (IEA) | GO:0010306
• sesquiterpenoid biosynthetic process (IEA) | GO:0016106
• sperm aster formation (IEA) | GO:0035044
• sperm DNA decondensation (IEA) | GO:0035041
• synaptic vesicle priming (IEA) | GO:0016082
• tertiary alcohol biosynthetic process (IEA) | GO:1902645
• transcription by RNA polymerase V (IEA) | GO:0001060
• tRNA import into mitochondrion (IEA) | GO:0016031

Domains

• ( PF00439 ) Bromodomain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:29523178: Saettone A, Garg J, Lambert JP, Nabeel-Shah S, Ponce M, Burtch A, Thuppu Mudalige C, Gingras AC, Pearlman RE, Fillingham J (2018) The bromodomain-containing protein Ibd1 links multiple chromatin-related protein complexes to highly expressed genes in Tetrahymena thermophila. Epigenetics & chromatin 11(1):10

Sequences

>TTHERM_00449140(coding)
ATGAATGCTGCAATGATCAATATAAAAAATATAATATTGTTTTTAATACTGAATAGCAAG
CAAGCAAACAAAAATAGTAAAGAAAATTAAGCAGAAACTAAGAAAGAAATTTAGTGTAAT
TAAAGCAAAAATAATTAATTAAATACAGATAATACTATGAAAAGCAATACTACCAAGGAA
AAGGCGCCAAAAACAGAAGCAACAAAAACTAAGTTAGACAGAGAACTAATTAAGAAGCTT
CATAAAATTTTAAATAACTTAATAAATGATCCCGAATCTGGCGAATTCAGGAAGCCTGTT
TACTATAAAGCTCTTGGATTAGAAGATTATAAAAAGATTATAAAGAAGCCAATGGATTTA
AATAGTGTTCGCAGAAATTTGAACAAAAATTCATATGAGTTTCTTGAAGAGGTTCTTGAT
GATATATAATTAGTTTGGAATAATTGCAAGTTATACAACGAGCAAGGATCATGGATTTAT
TTAACTGCAGTCAAGCTTGAAACGTTTTTCCATGACCAATGTTTAGAGTAATTCCCAAAC
ACACCTCTGCCTAGCAACAAAATACCCGATAGAGCCCTCCTATTATAGTAATATAACGAG
AAGAGCAATAAACAAAAGTAATCTCAGTCTAATAAAGATTAAACTAATGAAGAAGAATAA
AAAGGAGCTTCAAACACTTTGCCTCTACCAAAATTGGCAAATCAAAGTTCAAATACATCA
ACTTCTAATCCTTAAACTATTGCTCAGTCTTTGATTACAACATAATCTGAGTTTAACCAA
AATAAGCAATCTCAAAATGGAAATAATTCAGCTTAAGCATCTCTTACTGCAGCTAATCAA
TCAAAGACTACAAATATTGATCTGCCTTTTAAATTTACTAAAAAAGGTATAAAAAGAATA
TCATAAAAATAAGTTGTTCATATACCTTTTATGAAATTTGCTAATGATAAATAAAAATTT
GATTAGCTTATACAGACTACCAAAGCAGTCTCTAAGCTTTTAACAAACCAACAAAAGCAA
ATAATAGATATAATTCAAGAGTTTTAGCCTTCAATTATACAAACAGATGAAAATGAAGTT
AAAAATGTTGATTTTAATTAAGTGTCAGAGTATACCTATGAATTGATAACTTCCTATCTG
AATTTACTTAAAAATCAAGAATCAAGTGAATAAGTAATGGAAATAGAATCTGATGATGAA
AATAATATTGAGATACTAAATAACTAGCAATCAAACAATGTATCTTTAAACGTATGA

>TTHERM_00449140(gene)
TTTGTATACTAATTATAAATGTGTTGATTTATTTATTTAATAGTCCATGCTACTTACTTG
GTATTGATCTATCAAAGAACATAAAAATGAATGCTGCAATGATCAATATAAAAAATATAA
TATTGTTTTTAATACTGAATAGCAAGCAAGCAAACAAAAATAGTAAAGAAAATTAAGCAG
AAACTAAGAAAGAAATTTAGTGTAATTAAAGCAAAAATAATTAATTAAATACAGATAATA
CTATGAAAAGCAATACTACCAAGGAAAAGGCGCCAAAAACAGAAGCAACAAAAACTAAGT
TAGACAGAGAACTAATTAAGAAGCTTCATAAAATTTTAAATAACTTAATAAATGATCCCG
AATCTGGCGAATTCAGGAAGCCTGTTTACTATAAAGCTCTTGGATTAGAAGATTATAAAA
AGATTATAAAGAAGCCAATGGATTTAAATAGTGTTCGCAGAAATTTGAACAAAAATTCAT
ATGAGTTTCTTGAAGAGGTTCTTGATGATATATAATTAGTTTGGAATAATTGCAAGTTAT
ACAACGAGCAAGGATCATGGATTTATTTAACTGCAGTCAAGCTTGAAACGTTTTTCCATG
ACCAATGTTTAGAGTAATTCCCAAACACACCTCTGCCTAGCAACAAAATACCCGATAGAG
CCCTCCTATTATAGTAATATAACGAGAAGAGCAATAAACAAAAGTAATCTCAGTCTAATA
AAGATTAAACTAATGAAGAAGAATAAAAAGGAGCTTCAAACACTTTGCCTCTACCAAAAT
TGGCAAATCAAAGTTCAAATACATCAACTTCTAATCCTTAAACTATTGCTCAGTCTTTGA
TTACAACATAATCTGAGTTTAACCAAAATAAGCAATCTCAAAATGGAAATAATTCAGCTT
AAGCATCTCTTACTGCAGCTAATCAATCAAAGACTACAAATATTGATCTGCCTTTTAAAT
TTACTAAAAAAGGTATAAAAAGAATATCATAAAAATAAGTTGTTCATATACCTTTTATGA
AATTTGCTAATGATAAATAAAAATTTGATTAGCTTATACAGACTACCAAAGCAGTCTCTA
AGCTTTTAACAAACCAACAAAAGCAAATAATAGATATAATTCAAGAGTTTTAGCCTTCAA
TTATACAAACAGATGAAAATGAAGTTAAAAATGTTGATTTTAATTAAGTGTCAGAGTATA
CCTATGAATTGATAACTTCCTATCTGAATTTACTTAAAAATCAAGAATCAAGTGAATAAG
TAATGGAAATAGAATCTGATGATGAAAATAATATTGAGATACTAAATAACTAGCAATCAA
ACAATGTATCTTTAAACGTATGATTCAATAAAAGTAATAAAAACAAACTTAAGCTAAATT
AATCTAATATAATGAAATTATTTTAAAATAAAAAAACAAACTCTTAGTAAATCTATTGCA
TAGTTAATTAAGGTGGTAATAACTCAAATTTCATCAAACATTTTTAATATGTATGTATAT
CCAAAGTATTTTTATAAAAATTATTTGAATATAAATCAGAAAATAAATAAT

>TTHERM_00449140(protein)
MNAAMINIKNIILFLILNSKQANKNSKENQAETKKEIQCNQSKNNQLNTDNTMKSNTTKE
KAPKTEATKTKLDRELIKKLHKILNNLINDPESGEFRKPVYYKALGLEDYKKIIKKPMDL
NSVRRNLNKNSYEFLEEVLDDIQLVWNNCKLYNEQGSWIYLTAVKLETFFHDQCLEQFPN
TPLPSNKIPDRALLLQQYNEKSNKQKQSQSNKDQTNEEEQKGASNTLPLPKLANQSSNTS
TSNPQTIAQSLITTQSEFNQNKQSQNGNNSAQASLTAANQSKTTNIDLPFKFTKKGIKRI
SQKQVVHIPFMKFANDKQKFDQLIQTTKAVSKLLTNQQKQIIDIIQEFQPSIIQTDENEV
KNVDFNQVSEYTYELITSYLNLLKNQESSEQVMEIESDDENNIEILNNQQSNNVSLNV