Identifiers and Description

Gene Model Identifier

TTHERM_00459230

Standard Name

DMC1 (Disrupted Meiotic CDNA 1)

Aliases

PreTt20354 | 53.m00256 | 3712.m00114

Description

DMC1 meiotic recombination protein DMC1 putative; Meiosis-specific RecA; homolog of S. cerevisiae DMC1

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• micronucleus (IDA) | GO:0031040

Biological Process

• double-strand break repair (IMP) | GO:0006302
• meiotic nuclear division (IMP) | GO:0007126

Domains

• ( PF00154 ) recA protein
• ( PF08423 ) Rad51
• ( TIGR02236 ) DNA repair and recombination protein
• ( TIGR02237 ) DNA repair and recombination protein
• ( TIGR02238 ) meiotic recombinase Dmc1
• ( TIGR02239 ) DNA repair protein RAD51

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_13810.1	5.999773492405769e-126
	Description: hypothetical protein (252 aa)
Oxytricha	Contig4225.0.0.g49	7.000620174165717e-94
	Description: Rad51
DictyBase	DDB_G0273611	8.003693242657371e-87
	Description: rad51-2 on chromosome: 2 position 3169189 to 3170422
SGD	YER179W	9.99562814099401e-84
	Description: DMC1 Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein
WormBase	WBGene00004297	1.0002223712504345e-79
	Description: locus:rad-51 status:Confirmed UniProt:G5EGG8 protein_id:CAE47473.1
Stentor Coeruleus	SteCoe_17466	7.47197233734299e-43
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:21483758: Howard-Till RA, Lukaszewicz A, Loidl J (2011) The recombinases Rad51 and Dmc1 play distinct roles in DNA break repair and recombination partner choice in the meiosis of Tetrahymena. PLoS genetics 7(3):e1001359

Sequences

>TTHERM_00459230(coding)
ATGAACGATTGTTACTCTGATAAAGAAGATAATGAAGAATAAAACTAAATTGCTCAAGAA
GAGATCTTTTTAGTAGAAATGCTTGCAACTGAGGGAGTTAACAATAATGAAATACAAAAG
CTTAAAAAGAATGGAATCCTTTCACTCAAATCTTTAGTTATGAACACAAAGAGGGATCTT
GTTAATATCTATGGAATTCCTGATAATAAAGCTGATTCATATGTCAAAAAAGCTTCAGAA
ATATTAGCTCGATCTGAAAACAGCAGGTTATTCAGCAGTGAGTTTGTTCTCGGTACTACT
GTACTATAAAGAAGGAGTTAAATAAGAAGAATATCAACAGGATCCAAGGCTTTAGATGAT
ATATTGAATGGGGGAATAGAGTCTCAAAGCATAACAGAATTTTATGGAGAATATCGTTCA
GGCAAAACATAAATAGCTCATACTGCATGCGTTCTGGCTCAATCTTAAGATCATTGCTAA
AGTCCAGGAAAAGTTTTATACATTGATACTGAAGGAACCTTCAGACCTGAAAGAATATGC
TAAATAGCTTCGCACTACGGAATGGAGGGTGAATATGCCCTAAGTAATATAATTTATGGG
AGAGCCTATAACGTAGATTAATAAAACACATTGCTTATTAAAGGAGCCCAATTAATGGTA
GAGGAAAATTGTTTTGCTCTACTAGTTGTTGATTCAATAATGGCTAATTTTAGATGCGAT
TTTTCTGGAAGAGGAGATCTCTCTGAAAGACAATAAGCACTTGGCAAGTTTATGAGCAGA
TTATAAAGAATGGCTGCTGAATTTAATATCGCAGTGATTATAACAAACTAAGTTATGGCT
GATCCAAGTGGAGCCATGACTGGAGGCGCTATACCCTAGCCCAAGCCAATTGGAGGCCAT
ATTTTAGCCCATGCATCGACATAGCGCTTATTCATGAAGAAGAAAACTGATAACATCCGT
AAAGTAAAGCTGGTTGATTCACCTTATTTGTAAGATAAAGAAGTTGATATTATGGTTAGC
GACAGAGGAGTAGGAGATGTTGAATGTGATAAAAAGCCTTCTACTGGTTGA

>TTHERM_00459230(gene)
ATGAACGATTGTTACTCTGATAAAGAAGATAATGAAGAATAAAACTAAATTGCTCAAGAA
GAGATCTTTTTAGTAGAAATGCTTGCAACTGAGGGAGTTAACAATAATGAAATACAAAAG
CTTAAAAAGGTATGTAGTTGTTATATTAATTCACAATAAGACAATATCATTGATTATATA
AAAATAAATATAAAGAATGGAATCCTTTCACTCAAATCTTTAGTTATGAACACAAAGAGG
GATCTTGTTAATATCTATGGAATTCCTGATAATAAAGCTGATTCATATGTCAAAAAAGCT
TCAGAAATATTAGCTCGATCTGAAAACAGCAGGTTATTCAGCAGTGAGTTTGTTCTCGGT
ACTACTGTACTATAAAGAAGGAGTTAAATAAGAAGAATATCAACAGGATCCAAGGCTTTA
GATGATATATTGAATGGGGGAATAGAGTCTCAAAGCATAACAGAATTTTATGGAGAATAT
CGTTCAGGCAAAACATAAATAGCTCATACTGCATGCGTTCTGGCTCAATCTTAAGATCAT
TGCTAAAGTAAAACAAGCATAAGAAATTTTAACTGGTTTTAAATAAATTATTCTGCTTAA
ATATAGCCATTTAAATAAAAAAATAGGTCCAGGAAAAGTTTTATACATTGATACTGAAGG
AACCTTCAGACCTGAAAGAATATGCTAAATAGCTTCGCACTACGGAATGGAGGGTGAATA
TGCCCTAAGTAATATAATTTATGGGAGAGCCTATAACGTAGATTAATAAAACACATTGCT
TATTAAAGGAGCCCAATTAATGGTAGAGGAAAATTGTTTTGCTCTACTAGTTGTTGATTC
AATAATGGCTAATTTTAGATGCGATTTTTCTGGAAGAGGAGATCTCTCTGAAAGACAATA
AGCACTTGGCAAGTTTATGAGCAGATTATAAAGAATGGCTGCTGAATTTAATATCGCAGT
GGTAAATAAATACATTCTTTATTTTATCAACACCTTTCTGCTTTTATACGATTCTTATTC
TTAAAATTAACAAACAGATTATAACAAACTAAGTTATGGCTGATCCAAGTGGAGCCATGA
CTGGAGGCGCTATACCCTAGCCCAAGCCAATTGGAGGCCATATTTTAGCCCATGCATCGA
CATAGCGCTTATTCATGAAGAAGAAAACTGATAACATCCGTAAAGTAAAGTAAAACAAAA
CAAAACTTCTTAAATCACAAATAAAAAATTTTTCTTTCACTTAATTAAAGGCTGGTTGAT
TCACCTTATTTGTAAGATAAAGAAGTTGATATTATGGTTAGCGACAGAGGAGTAGGAGAT
GTTGAATGTGATAAAAAGCCTTCTACTGGTTGA

>TTHERM_00459230(protein)
MNDCYSDKEDNEEQNQIAQEEIFLVEMLATEGVNNNEIQKLKKNGILSLKSLVMNTKRDL
VNIYGIPDNKADSYVKKASEILARSENSRLFSSEFVLGTTVLQRRSQIRRISTGSKALDD
ILNGGIESQSITEFYGEYRSGKTQIAHTACVLAQSQDHCQSPGKVLYIDTEGTFRPERIC
QIASHYGMEGEYALSNIIYGRAYNVDQQNTLLIKGAQLMVEENCFALLVVDSIMANFRCD
FSGRGDLSERQQALGKFMSRLQRMAAEFNIAVIITNQVMADPSGAMTGGAIPQPKPIGGH
ILAHASTQRLFMKKKTDNIRKVKLVDSPYLQDKEVDIMVSDRGVGDVECDKKPSTG