Identifiers and Description

Gene Model Identifier

TTHERM_00460480

Standard Name

COM1 (Meiotic double-strand break-induced reCOMbination 1)

Aliases

PreTt25699 | 54.m00155 | 3823.m01074

Description

COM1 Com1p is required for meiotic double-strand break repair and full homologous pairing; homolog of S. cerevisiae COM1/SAE2; hypothetical protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Biological Process

• double-strand break repair (IMP) | GO:0006302
• homologous chromosome pairing at meiosis (IMP) | GO:0007129
• meiosis I (IMP) | GO:0007127

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:26519827: Lukaszewicz A, Shodhan A, Loidl J (2015) Exo1 and Mre11 execute meiotic DSB end resection in the protist Tetrahymena. DNA repair 35( ):137-43
2. Ref:20422424: Lukaszewicz A, Howard-Till RA, Novatchkova M, Mochizuki K, Loidl J (2010) MRE11 and COM1/SAE2 are required for double-strand break repair and efficient chromosome pairing during meiosis of the protist Tetrahymena. Chromosoma 119(5):505-18

Sequences

>TTHERM_00460480(coding)
ATGCTTGGGTTAGAATAAAATTGTTTTATTAAAGAATACAGGAAGTAGGTAGATAAAGAG
GCTCTAAATTAAATATAAGATGCTGCTTTATCAAATTTAATGAATGCATTTGGGTAGATG
AATTAAACATATTCTGTACTTTTCAAAGATATTTGTCTTACTTTTGGCGCTTTATTATCA
ATAAAGGAAGAGTTAAAGGACTATCGCTAGGAAATGTTTTAGAAATAAAGCGAGAAAATT
ATCTAGGAGAAGATTCAGAAGGAAATGATTCAATAAAAAGATGAGCAATTGGAATTCCTC
TAAAAGTAATTGAAAATAGTTTAACTGCAATCTGATTAAGATAGAAATTCTAAACAGGCA
ATTCAAGAGAGGGATTAGGCCATAAGTTCATATAAATAAAGACTTTTTGATTTATAAGAA
AATGAAAAGAAATTGCTCAGCGAAAAGTCTTAGCTTCAGACTAGAATTGAGTTACTTGAA
GAATAATAAAATTCTAACAAAGTTGCAATCTTAGAAAAGCAAACCACTCTTCATTAAGGT
TATAAACTCACATTTTTAAATAACGAATTAAAAGAATCTCTTATTGAACAACCTTCAAAT
GTATTTTAATAAGAAAACGGGGTTAATAAAAATAAAATATATAGCTTGGATAATAATTAG
ATATAAAAGAATAATACTTCCCTTTTAAGTAAATTTAAGTAAGACCAATCTGATTAAGAG
GTGTAAAATAATACATAACTTGCTCAAAAAAACTAATAGGATATTTATTATAGTAACAAA
ATAAATCAGATAAAACCTGAAACATTTTCAAATCAAGATCCTTCAGTTTATTTACAAGAA
AGCTATGTATAAAGTTCACTTAATGCAAATAATATTTTAGGTTCAAAAAAGATTACAGAT
GAAGAGATTTTTATGATGTAAAAAAGAGAAGCTGAAATTAAAAAAAAGAAATAGGAAGAT
GAACATTTAAAGAATTAATAATACATGTCAAGTTTGAATTACAATAAAATAATTTCTGAT
AAAAATAAAAATTAGAATTTAATGAATAATAAAATTATTGAGTAATCTAAAGAGAGTTCT
ATGGGATCTTTATTCAATAAGACAGCTTTTGATCAAAGCTCAATTAATAATCAAAGTAAT
GCTAGTGTAAGAATGGAATTAGAAGATTCTAGTGCTGGATAACAGCTTTAAAGATATAAA
GTAAGCTTAAATGATAGAAAAATGGTAGCTGAAAATAATCTAAATGCAACAGATGATTTA
TTAAAAAATAAAATGGAGCAGGAAGATAATGAAAAAGAGAGTTCTGACTCTTAGTATAAC
TGGAATTTAAAAATCGATTTGAAAAACAATAACGAATAATAGCAGCAATTTCCATAGGAA
AGCAATAACAATAGTGGAAACAAAAAGAGATTCAAAAAGTAACAATTAAAAAAATCAGAT
TCTTTTGCCACAAATGCAAACTAGAATTCTGAATTAGAAAACACCACAGCTAGTGTTATT
AGTTTACAAAACTAACAATAAAATTAAAATTATGAAATTTAAGATCAATAAAGCAATTAA
ATGCTCTTAGGTCAAAAGAAAAATTTAAATATTAATAAAGGTAGAGTTGCTAATAATAAA
TTTATGAAAGACATAGAATTAGATGATGAAAGTGGGGACAAAGACTAACCCTAATAAAAT
GATATATTTGCTCAGTTTCAATATAAAAAAAGAGGTACTTCAAACTAAGAAGTTCAAGTA
GCTGAAACTTTTAACATGTATAACAAATAAAATTAGAGACCATTAAATCCTCGTAAAAAA
GAAGATAGAGAAAAATTAAAAACTTTTAATTGTGGCAGATGCAAAGCCGCATATCAAACT
TTGGGAGAAGAATTCTGTGGTAATTGTTCTAAACACAGATCAGAATACACGCCTCCTCAC
ACTCCCGAAGCCCATTATTAAAAATTTTCCTAGTCAGAAGATGATTCTAATTGA

>TTHERM_00460480(gene)
ATCTGCATTTTAAATACATAAGAATTCATTAACTAACAAATATACCAAGAATCTCTCATG
TAAATTACTAATTTGATATTTATCTCTCAGTATAAACAAACTTTAAAATTATAATTGTAT
AGTGGTATAAATAATAAATATAAATTTTTGAGCAAAAATGCTTGGGTTAGAATAAAATTG
TTTTATTAAAGAATACAGGAAGTAGGTAGATAAAGAGGCTCTAAATTAAATATAAGATGC
TGCTTTATCAAATTTAATGAATGCATTTGGGTAGATGAATTAAACATATTCTGTACTTTT
CAAAGATATTTGTCTTACTTTTGGCGCTTTATTATCAATAAAGGAAGAGTTAAAGGACTA
TCGCTAGGAAATGTTTTAGAAATAAAGCGAGAAAATTATCTAGGAGAAGATTCAGAAGGA
AATGATTCAATAAAAAGATGAGCAATTGGAATTCCTCTAAAAGTAATTGAAAATAGTTTA
ACTGCAATCTGATTAAGATAGAAATTCTAAACAGGCAATTCAAGAGAGGGATTAGGCCAT
AAGTTCATATAAATAAAGACTTTTTGATTTATAAGAAAATGAAAAGAAATTGCTCAGCGA
AAAGTCTTAGCTTCAGACTAGAATTGAGTTACTTGAAGAATAATAAAATTCTAACAAAGT
TGCAATCTTAGAAAAGCAAACCACTCTTCATTAAGGTTATAAACTCACATTTTTAAATAA
CGAATTAAAAGAATCTCTTATTGAACAACCTTCAAATGTATTTTAATAAGAAAACGGGGT
TAATAAAAATAAAATATATAGCTTGGATAATAATTAGATATAAAAGAATAATACTTCCCT
TTTAAGTAAATTTAAGTAAGACCAATCTGATTAAGAGGTGTAAAATAATACATAACTTGC
TCAAAAAAACTAATAGGATATTTATTATAGTAACAAAATAAATCAGATAAAACCTGAAAC
ATTTTCAAATCAAGATCCTTCAGTTTATTTACAAGAAAGCTATGTATAAAGTTCACTTAA
TGCAAATAATATTTTAGGTTCAAAAAAGATTACAGATGAAGAGATTTTTATGATGTAAAA
AAGAGAAGCTGAAATTAAAAAAAAGAAATAGGAAGATGAACATTTAAAGAATTAATAATA
CATGTCAAGTTTGAATTACAATAAAATAATTTCTGATAAAAATAAAAATTAGAATTTAAT
GAATAATAAAATTATTGAGTAATCTAAAGAGAGTTCTATGGGATCTTTATTCAATAAGAC
AGCTTTTGATCAAAGCTCAATTAATAATCAAAGTAATGCTAGTGTAAGAATGGAATTAGA
AGATTCTAGTGCTGGATAACAGCTTTAAAGATATAAAGTAAGCTTAAATGATAGAAAAAT
GGTAGCTGAAAATAATCTAAATGCAACAGATGATTTATTAAAAAATAAAATGGAGCAGGA
AGATAATGAAAAAGAGAGTTCTGACTCTTAGTATAACTGGAATTTAAAAATCGATTTGAA
AAACAATAACGAATAATAGCAGCAATTTCCATAGGAAAGCAATAACAATAGTGGAAACAA
AAAGAGATTCAAAAAGTAACAATTAAAAAAATCAGATTCTTTTGCCACAAATGCAAACTA
GAATTCTGAATTAGAAAACACCACAGCTAGTGTTATTAGTTTACAAAACTAACAATAAAA
TTAAAATTATGAAATTTAAGATCAATAAAGCAATTAAATGCTCTTAGGTCAAAAGAAAAA
TTTAAATATTAATAAAGGTAGAGTTGCTAATAATAAATTTATGAAAGACATAGAATTAGA
TGATGAAAGTGGGGACAAAGACTAACCCTAATAAAATGATATATTTGCTCAGTTTCAATA
TAAAAAAAGAGGTACTTCAAACTAAGAAGTTCAAGTAGCTGAAACTTTTAACATGTATAA
CAAATAAAATTAGAGACCATTAAATCCTCGTAAAAAAGAAGATAGAGAAAAATTAAAAAC
TTTTAATTGTGGCAGATGCAAAGCCGCATATCAAACTTTGGGAGAAGAATTCTGTGGTAA
TTGTTCTAAACACAGATCAGAATACACGCCTCCTCACACTCCCGAAGCCCATTATTAAAA
ATTTTCCTAGTCAGAAGATGATTCTAATTGAAAAAAAGAGTGCTAAAAACATATTTTAAA
ATTCAAATAAATGAATGAATAAATTAATTCTTAATGAGATTTCAAAATTGATAAATAAAA
TAATTAAATAATAAAATTAATAAAATAAATATGAAAATCACCAAAATTATTAATATAAAA
TGAATGTTCTTATTTAAATTAATTCTATTTTCTATTGTGTTTTTTATTTGTACTATCTTT
ATAGTTGTTATAATATATCTAAAAGAG

>TTHERM_00460480(protein)
MLGLEQNCFIKEYRKQVDKEALNQIQDAALSNLMNAFGQMNQTYSVLFKDICLTFGALLS
IKEELKDYRQEMFQKQSEKIIQEKIQKEMIQQKDEQLEFLQKQLKIVQLQSDQDRNSKQA
IQERDQAISSYKQRLFDLQENEKKLLSEKSQLQTRIELLEEQQNSNKVAILEKQTTLHQG
YKLTFLNNELKESLIEQPSNVFQQENGVNKNKIYSLDNNQIQKNNTSLLSKFKQDQSDQE
VQNNTQLAQKNQQDIYYSNKINQIKPETFSNQDPSVYLQESYVQSSLNANNILGSKKITD
EEIFMMQKREAEIKKKKQEDEHLKNQQYMSSLNYNKIISDKNKNQNLMNNKIIEQSKESS
MGSLFNKTAFDQSSINNQSNASVRMELEDSSAGQQLQRYKVSLNDRKMVAENNLNATDDL
LKNKMEQEDNEKESSDSQYNWNLKIDLKNNNEQQQQFPQESNNNSGNKKRFKKQQLKKSD
SFATNANQNSELENTTASVISLQNQQQNQNYEIQDQQSNQMLLGQKKNLNINKGRVANNK
FMKDIELDDESGDKDQPQQNDIFAQFQYKKRGTSNQEVQVAETFNMYNKQNQRPLNPRKK
EDREKLKTFNCGRCKAAYQTLGEEFCGNCSKHRSEYTPPHTPEAHYQKFSQSEDDSN