Identifiers and Description

Gene Model Identifier

TTHERM_00467740

Standard Name

NRK18 (NIMA-Related Kinase)

Aliases

PreTt18676 | 55.m00231 | 3710.m00080

Description

NRK18 plant dual-specificity MAP kinase kinase family domain protein; NIMA-Related Kinase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) protein kinase domain
• ( PF06476 ) Protein of unknown function (DUF1090)
• ( PF07122 ) Variable length PCR target protein
• ( PF07714 ) protein tyrosine kinase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_15719.1	9.997093137033517e-262
	Description: protein kinase domain-containing protein (1132 aa)
Oxytricha	Contig22240.0.g43	1.9992336839414155e-150
	Description: Protein kinase domain
DictyBase	DDB_G0270814	5.000940857796793e-119
	Description: nek2 on chromosome: 1 position 4847143 to 4848761
SGD	YAR018C	1.000371485572848e-69
	Description: KIN3 Nonessential serine/threonine protein kinase; possible role in DNA damage response
Stentor Coeruleus	SteCoe_13566	1.733141042341547e-58
	Description: None
WormBase	WBGene00008956	7.999866353200662e-52
	Description: locus:nekl-3 status:Confirmed UniProt:G5EFM9 protein_id:CAA92169.2

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00467740(coding)
ATGGATAACTACGAAATATTAGGCTAAATCGGAAAGGGTAGCTTTGGTTTAGTATAAAAG
ATTAAAAGGAAATCCGACGGGAAAGTACTTGTTTGGAAAGAAATGAATTATGGAAGAATG
AGTGAAAGAGAAAAGCAATAGCTTGTAGCAGAAGTAAATATAATACGAGAGCTTAAACAC
CCAAATATAGTGAGATATTATGACAGAATCATTGAGAAAAAAGACACTAAAATTTATATT
ATTATGGAATACTGCGAGGGAGGAGATGTAGGCACTCTCTTAAAGAAATGCAAGAAAGAA
AAAGATTATATTGCTGAAGATGTTATTTGGAAAATATTTACTTAAATAATTCTTGCACTC
AATGAATGTCACAACAGACCTTAGGGAAAAATATTACACAGAGATCTTAAACCTGCAAAT
ATATTTCTTGACGCTTAAAATAATATTAAACTAGGCGATTTTGGTTTAAGTAGAGTCATG
GGAGAATAATCTGAATTTGCAGATACACATGTAGGAACACCATACTACATGTCACCTGAG
TAAATATAAGAGAAAAAATATAATGAAAAGAGTGATATTTGGAGTGCTGGTTGTCTTTTA
TATGAAATGGCTGCTTTAAAGCCTCCCTTTGAAGCTACTAATCATCTTTCACTTGCTATA
AAAATTAAAAGTGGTAAATTTGAAAGACTACCTTTAAGATACAGTGAAGAATTGTAAAAA
TTAATTGAAAGTATGGTTCATATAGACCCTGAAAAGAGACCTTCTGTTTAAAATATTCTC
GAATTGCCATAAATAAACCTTCGTTTGAAGGAAAGAAAGTTGAGAGAAAAGCACTCTTAA
ATAAAATTAAAAGAAGACGAGCTAAAAAAGCGCGAGGAACAACTGCAAGAAAGAATTGAT
TAAATAGAAAAAAAGGAAAAAGACTTAACTGCCCAAGAATAAACTTTAAAGGATTTGGAG
GAATAAGTAAAATAAATTGAAGCTCAGTTAAACATAAGGTCATCTCAAAATTCACTTCAA
TAATCTGAAGAAGATATTTTTTAAAGATAAGATAAATAGACAAATAATAATAACAATGCA
GGAGTATTACCTTAAAAAAGTGCAAGAGGAGAATATTAATTGCTAAGTTAAAATTTAAAC
AGTTTTGGTAAAGACCTCATGATGCTAAATAAAGGCAGCGTTGAAAACAATAGTAGTGGC
AGCTCAAGTAAAAATAGCACTGCTACAGCATCAAATAATACTTTTGAGATATTTAAAAAA
GAAAAAGAAAATATGATAAACAATGGAAGCAATATCTAAAGCAATTTATAAAGTATAGAG
AATTACAGAAAAGAAAAGGAAATTCAAAAATAGCTTTAATCTTACTCAAGCAACAAATAT
CCAATCTTTTAAAAATCTAATTCATCTATTGTTTCCTAGAGTTTAACGGATTAATAAATG
CTATTGCAACAATAAAGCTCTTAGGATACAACTTCATCTTAAGTAGTTTAGCAATAATCT
AGTGAAAATAATTAATCTAATTTGAAATTAAGGGGTAATATTGCTGATACCTAGTAAACA
TAAAGCAGCTGTTCTTCTAACTCCAGCAACAATGATGCTAATGCTAGTAACCCTATAACA
GCAAACACTAAAGACAAAAATTATACTCTGTACTAGAGAAGAGAGCAAGAAGCTTTTTAA
AAAACTCCTAACAATAACAGCAATTTACACTAAAATTATCATACTTTGAATAGATAAGGG
GAAATTGAAAGTGTAACTAAAAAACATACTTCTTATTCAAAAGACCATTAATACAAGTCT
GTGGATCATTTCACATCTATTTAAAATAACAACAACTCTAGCTCAAAAAAAGATGAGAGT
ACTGCCTTTAGTACTACTTGTAAGTAAATACCTTAGTCAGCATCATAAAATTAGAATATT
GCAAACCAAAGTAGTAATAAATCTTCTCATAAAAGCAGCAGTGAAAATCTCCCTAAAAAG
AGTACTGTTGCTTAAATTTCTTCTACAAATAACTAAAATTAAATTGATAATTAAAACTAA
GAAAATTCTTCTGCTGCTTCTAATAATAACAATAATAATAATAATACAGGAATGTCTGCA
TTTGAAAGATACAAAGCTTCCATTTTATAGCAGTAACAATAGTAATAAAATTAAAATAAT
AATGGTTATTAAAATAAATATGCATAAATTAAATCTAAAGTGCGTTAAGCAAGTTAAGAT
TCCATGGATGATAATGAATAATAAACTATGAACAATAATTACACTTCAAAGCTTCATACA
TAATAACCCATTTCAAGTAAATTAAGAGCACAGACATCAATCGATTCAGTTTCTGTAAAA
TAAAACCAAGATAATAAAAACTACTTGCTTAATTATAAAAAGGATGCTCCTTCTGGTAGC
ACAGCATCAGCTGCAACAATTACTAGAAGATCAGCAAACACTACAATAGATTCAGTAAAG
TATTCTCAAATTAATAATTCTTCAAATATGTAAGGACCTACTAATAATAATAATTAAAAT
GCCTCTTATGAGATATATAAATAAGCAAACATAAAAAGAACAGATAGTTATAAAGAAAAC
ACTTTCAAAAATATAATGTAATAAAATAATTTCATCAATAAGCAATAAGAAGCTGCAACT
CAATCTTCTTCTAATAATAATTAACAAATACATTCTTCAACAAATTTAGCTTAAAATTAA
AAGAATTTTTAGAAAAACAGATCATCATTAGAGCCTAAAAATAGATTCCACTCTTAGCAT
AGCACAACTTCATCATCATCAACAACAACAGCATAAACTGCTATACAATCTACACAATAA
CCATAGTAGTCTTCATCGTAGGTTGCTTTAAACTCAAATAAACCTCCAATTACTATGATG
AATAACAATGGAGCATTAAATGGGAATAGTAATAATAACGAAGATGCCTTACTTAATTTC
AAAACGCTCCCTAATACCGAATTTCAATATGATTCCAATAATGTTAATAAAATGTAAATA
AAGAAGAAAAACAATAACAGCTTCACAACAACATCATAAAATATAAGCAACACTTATTTA
AATAGTAACAATAATTATATAAATAATTAACCACGTTCTACTACTAATAGTAACACAATA
GGTAATAACTCAGCTCGTATAAATAATACAGAATAAAGTATTGAAAGAAAAAAAGAATTT
CCTCGTCCTAGAAATAATTATCTGTTACCTTAATCCAGATAAACTTTAAACAGTAATCAA
AATCCAGATGCTAATATAAAGAATTATTTCTCAGAATAACCAAGCAACCTTATGACTGTG
CAGACAGACTAATTGTATAATAAATATAATTTAAGAAAGATAGGCGATAACATTATTTCT
CCATCAGTATAGCACGTTTCATCAAACTAATATAGAACTGCTACTTAATACTGA

>TTHERM_00467740(gene)
ATGGATAACTACGAAATATTAGGCTAAATCGGAAAGGGTAGCTTTGGTTTAGTATAAAAG
ATTAAAAGGAAATCCGACGGGAAAGTACTTGTTTGGAAAGAAATGAATTATGGAAGAATG
AGTGAAAGAGAAAAGCAATAGCTTGTAGCAGAAGTAAATATAATACGAGAGCTTAAACAC
CCAAATATAGTGAGATATTATGACAGGTATATTTATTAAAGAGTTTTACACTATTGCATT
TAAAAAATAAGAGAATGAATTTGAATTAAATTCCTGATTTAAGTCTAAAATTTAATCTTT
TATGAGAATAAACTATGCATTTGTCAAAGTTTATCAATTTGGCTTTATTTAAATGTAATG
CCCACATTTAAATTTGAGCTATGCATCAGGCAGGCAAATCAATATCGTATTTTCTATTTT
TTTGATATTGCCTTTTAAATGAAAAAGAGAGTATTAAATCAAAATAAATGTTTTTCAAGA
TATTAATTAAGATGCAATTATTAAATTTTAAAAATCTTTGGCTGATTATTTGATTTCAAA
TTATAAATCACAACCTTTTTACTTATTTTTCCTTTGCATTTTCAAATAATCTCTTCTCTT
TAAACAACTTCAAATTTATACGGAATGTTGTGGTAACGAGCGAGAAAATTAATTCAAAAT
CAGTTTTTAGTCTTTGCCTATTTTACATCAACATGCATGAGAATTTGCTTATTTATTTAT
TTGTTTTAACGAATTTAAAATATGTTTGTTTGAACAAATTATTCAATTTGAAAAAATAAA
TAAAAAAATATTAAAGCAAAATATTTTAAATCTTCTTTGGCTATTTGCATTTATTTAAAT
AATTATTATAAAATTTATAGAATCATTGAGAAAAAAGACACTAAAATTTATATTATTATG
GAATACTGCGAGGGAGGAGATGTAGGCACTCTCTTAAAGAAATGCAAGAAAGAAAAAGAT
TATATTGCTGAAGATGTTATTTGGAAAATATTTACTTAAATAATTCTTGCACTCAATGAA
TGTCACAACAGACCTTAGGGAAAAATATTACACAGAGATCTTAAACCTGCAAATATATTT
CTTGACGCTTAAAATAATATTAAACTAGGCGATTTTGGTTTAAGTAGAGTCATGGGAGAA
TAATCTGAATTTGCAGATACACATGTAGGAACACCATACTACATGTCACCTGAGTAAATA
TAAGAGAAAAAATATAATGAAAAGAGTGATATTTGGAGTGCTGGTTGTCTTTTATATGAA
ATGGCTGCTTTAAAGCCTCCCTTTGAAGCTACTAATCATCTTTCACTTGCTATAAAAATT
AAAAGTGGTAAATTTGAAAGACTACCTTTAAGATACAGTGAAGAATTGTAAAAATTAATT
GAAAGTATGGTTCATATAGACCCTGAAAAGAGACCTTCTGTTTAAAATATTCTCGAATTG
CCATAAATAAACCTTCGTTTGAAGGAAAGAAAGTTGAGAGAAAAGCACTCTTAAATAAAA
TTAAAAGAAGACGAGCTAAAAAAGCGCGAGGAACAACTGCAAGAAAGAATTGATTAAATA
GAAAAAAAGGAAAAAGACTTAACTGCCCAAGAATAAACTTTAAAGGATTTGGAGGAATAA
GTAAAATAAATTGAAGCTCAGTTAAACATAAGGTCATCTCAAAATTCACTTCAATAATCT
GAAGAAGATATTTTTTAAAGATAAGATAAATAGACAAATAATAATAACAATGCAGGAGTA
TTACCTTAAAAAAGTGCAAGAGGAGAATATTAATTGCTAAGTTAAAATTTAAACAGTTTT
GGTAAAGACCTCATGATGCTAAATAAAGGCAGCGTTGAAAACAATAGTAGTGGCAGCTCA
AGTAAAAATAGCACTGCTACAGCATCAAATAATACTTTTGAGATATTTAAAAAAGAAAAA
GAAAATATGATAAACAATGGAAGCAATATCTAAAGCAATTTATAAAGTATAGAGAATTAC
AGAAAAGAAAAGGAAATTCAAAAATAGCTTTAATCTTACTCAAGCAACAAATATCCAATC
TTTTAAAAATCTAATTCATCTATTGTTTCCTAGAGTTTAACGGATTAATAAATGCTATTG
CAACAATAAAGCTCTTAGGATACAACTTCATCTTAAGTAGTTTAGCAATAATCTAGTGAA
AATAATTAATCTAATTTGAAATTAAGGGGTAATATTGCTGATACCTAGTAAACATAAAGC
AGCTGTTCTTCTAACTCCAGCAACAATGATGCTAATGCTAGTAACCCTATAACAGCAAAC
ACTAAAGACAAAAATTATACTCTGTACTAGAGAAGAGAGCAAGAAGCTTTTTAAAAAACT
CCTAACAATAACAGCAATTTACACTAAAATTATCATACTTTGAATAGATAAGGGGAAATT
GAAAGTGTAACTAAAAAACATACTTCTTATTCAAAAGACCATTAATACAAGTCTGTGGAT
CATTTCACATCTATTTAAAATAACAACAACTCTAGCTCAAAAAAAGATGAGAGTACTGCC
TTTAGTACTACTTGTAAGTAAATACCTTAGTCAGCATCATAAAATTAGAATATTGCAAAC
CAAAGTAGTAATAAATCTTCTCATAAAAGCAGCAGTGAAAATCTCCCTAAAAAGAGTACT
GTTGCTTAAATTTCTTCTACAAATAACTAAAATTAAATTGATAATTAAAACTAAGAAAAT
TCTTCTGCTGCTTCTAATAATAACAATAATAATAATAATACAGGAATGTCTGCATTTGAA
AGATACAAAGCTTCCATTTTATAGCAGTAACAATAGTAATAAAATTAAAATAATAATGGT
TATTAAAATAAATATGCATAAATTAAATCTAAAGTGCGTTAAGCAAGTTAAGATTCCATG
GATGATAATGAATAATAAACTATGAACAATAATTACACTTCAAAGCTTCATACATAATAA
CCCATTTCAAGTAAATTAAGAGCACAGACATCAATCGATTCAGTTTCTGTAAAATAAAAC
CAAGATAATAAAAACTACTTGCTTAATTATAAAAAGGATGCTCCTTCTGGTAGCACAGCA
TCAGCTGCAACAATTACTAGAAGATCAGCAAACACTACAATAGATTCAGTAAAGTATTCT
CAAATTAATAATTCTTCAAATATGTAAGGACCTACTAATAATAATAATTAAAATGCCTCT
TATGAGATATATAAATAAGCAAACATAAAAAGAACAGATAGTTATAAAGAAAACACTTTC
AAAAATATAATGTAATAAAATAATTTCATCAATAAGCAATAAGAAGCTGCAACTCAATCT
TCTTCTAATAATAATTAACAAATACATTCTTCAACAAATTTAGCTTAAAATTAAAAGAAT
TTTTAGAAAAACAGATCATCATTAGAGCCTAAAAATAGATTCCACTCTTAGCATAGCACA
ACTTCATCATCATCAACAACAACAGCATAAACTGCTATACAATCTACACAATAACCATAG
TAGTCTTCATCGTAGGTTGCTTTAAACTCAAATAAACCTCCAATTACTATGATGAATAAC
AATGGAGCATTAAATGGGAATAGTAATAATAACGAAGATGCCTTACTTAATTTCAAAACG
CTCCCTAATACCGAATTTCAATATGATTCCAATAATGTTAATAAAATGTAAATAAAGAAG
AAAAACAATAACAGCTTCACAACAACATCATAAAATATAAGCAACACTTATTTAAATAGT
AACAATAATTATATAAATAATTAACCACGTTCTACTACTAATAGTAACACAATAGGTAAT
AACTCAGCTCGTATAAATAATACAGAATAAAGTATTGAAAGAAAAAAAGAATTTCCTCGT
CCTAGAAATAATTATCTGTTACCTTAATCCAGATAAACTTTAAACAGTAATCAAAATCCA
GATGCTAATATAAAGAATTATTTCTCAGAATAACCAAGCAACCTTATGACTGTGCAGACA
GACTAATTGTATAATAAATATAATTTAAGAAAGATAGGCGATAACATTATTTCTCCATCA
GTATAGCACGTTTCATCAAACTAATATAGAACTGCTACTTAATACTGA

>TTHERM_00467740(protein)
MDNYEILGQIGKGSFGLVQKIKRKSDGKVLVWKEMNYGRMSEREKQQLVAEVNIIRELKH
PNIVRYYDRIIEKKDTKIYIIMEYCEGGDVGTLLKKCKKEKDYIAEDVIWKIFTQIILAL
NECHNRPQGKILHRDLKPANIFLDAQNNIKLGDFGLSRVMGEQSEFADTHVGTPYYMSPE
QIQEKKYNEKSDIWSAGCLLYEMAALKPPFEATNHLSLAIKIKSGKFERLPLRYSEELQK
LIESMVHIDPEKRPSVQNILELPQINLRLKERKLREKHSQIKLKEDELKKREEQLQERID
QIEKKEKDLTAQEQTLKDLEEQVKQIEAQLNIRSSQNSLQQSEEDIFQRQDKQTNNNNNA
GVLPQKSARGEYQLLSQNLNSFGKDLMMLNKGSVENNSSGSSSKNSTATASNNTFEIFKK
EKENMINNGSNIQSNLQSIENYRKEKEIQKQLQSYSSNKYPIFQKSNSSIVSQSLTDQQM
LLQQQSSQDTTSSQVVQQQSSENNQSNLKLRGNIADTQQTQSSCSSNSSNNDANASNPIT
ANTKDKNYTLYQRREQEAFQKTPNNNSNLHQNYHTLNRQGEIESVTKKHTSYSKDHQYKS
VDHFTSIQNNNNSSSKKDESTAFSTTCKQIPQSASQNQNIANQSSNKSSHKSSSENLPKK
STVAQISSTNNQNQIDNQNQENSSAASNNNNNNNNTGMSAFERYKASILQQQQQQQNQNN
NGYQNKYAQIKSKVRQASQDSMDDNEQQTMNNNYTSKLHTQQPISSKLRAQTSIDSVSVK
QNQDNKNYLLNYKKDAPSGSTASAATITRRSANTTIDSVKYSQINNSSNMQGPTNNNNQN
ASYEIYKQANIKRTDSYKENTFKNIMQQNNFINKQQEAATQSSSNNNQQIHSSTNLAQNQ
KNFQKNRSSLEPKNRFHSQHSTTSSSSTTTAQTAIQSTQQPQQSSSQVALNSNKPPITMM
NNNGALNGNSNNNEDALLNFKTLPNTEFQYDSNNVNKMQIKKKNNNSFTTTSQNISNTYL
NSNNNYINNQPRSTTNSNTIGNNSARINNTEQSIERKKEFPRPRNNYLLPQSRQTLNSNQ
NPDANIKNYFSEQPSNLMTVQTDQLYNKYNLRKIGDNIISPSVQHVSSNQYRTATQY