Identifiers and Description
Gene Model Identifier
TTHERM_00467910Standard Name
NaKa1Aliases
PreTt18692 | 55.m00247 | 3710.m00096Description
Orthologue of S. cerevisiae Rrb1 (Ribosome assembly protein). Rrb1 ortholog in humans is known as GRWD1. NaKa-1 contains WD-40 repeats with domain architecture similar to RebL1 and Wdc1 in Tetrahymena (Nabeel-Shah et al. 2021).Genome Browser (Macronucleus)
Genome Browser (Micronucleus)
External Links
Gene Ontology Annotations
No Data fetched for Gene Ontology Annotations
Domains
- ( PF00400 ) WD domain, G-beta repeat
Gene Expression Profile
Vegetative Cell Cycle (Zhang et al., 2023)
GeneMania
Tetrahymena Stock Center
No Data fetched for Tetrahymena Stock Center
Homologs
Source Identifier Score Tetrahymena borealis EI9_15704.1 9.997093137033517e-262 Description: hypothetical protein (586 aa) Oxytricha Contig21203.0.g38 3.999284652801983e-113 Description: WD domain, G-beta repeat DictyBase DDB_G0291566 9.001701800865775e-93 Description: grwd1 on chromosome: 6 position 556339 to 557876 SGD YMR131C 2.0009381340492598e-66 Description: RRB1 Essential nuclear protein involved in early steps of ribosome biogenesis; physically interacts with the ribosomal protein Rpl3p WormBase WBGene00021899 1.9997677415930956e-65 Description: status:Confirmed UniProt:Q9N393 protein_id:CCD69848.1 Tetrahymena borealis EI9_15863.1 1.9997677415930956e-65 Description: hypothetical protein (1310 aa) Stentor Coeruleus SteCoe_7644 8.194012623990515e-40 Description: None
General Information
No Data fetched for General Information
Associated Literature
- Ref:34086947: Nabeel-Shah S, Garg J, Saettone A, Ashraf K, Lee H, Wahab S, Ahmed N, Fine J, Derynck J, Pu S, Ponce M, Marcon E, Zhang Z, Greenblatt JF, Pearlman RE, Lambert JP, Fillingham J (2021) Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila. Nucleic acids research ( ):
Sequences
>TTHERM_00467910(coding)
ATGAGTGACAATAAAAAGATAAGTTAAAAGAGAAAGCTTGAAACTGCTGAAGATGTTTCA
CTTAATATTAAAGAACAAAACTAGAAAAAAAATCCTAATAAGAAGAAAGGGGATTAAGCA
GTAGTTGACGAATTCGAAAAAAATGAAAATTTTGAAGAGGAAGAAGGATCTGAATTAGAA
TTTGAAGATTGTGAAGATGATATAGATGATGAATATGTTGATGAAAAGACATACAAAAAG
ATTATGTAAGGAAATTTCTAAGAAGATGAAGAGGAATGGGAAGACGATGGAGATGATGAC
GATGATGAAAATGAAGAAATTGGTAATGAAGAAGAAAAATAAGACATAAATGCAAAGAAG
AGAAATAAAAAAAATAAAAACTAAAAAGTTGAATTTATTGATGTTTAATAAAAGCCTTTC
ATGGGTACTGAAAAGAATTTAGAAGAAGATGAAATTCTAGATTTCGATAATAAGGCATAC
GAAATGCTTCATAGAGCTAACACTGAATGGCCTTGCTTGTCATGTGATTTTGTAACTGGA
GAACCTCATAATATTAATAACCCTGGCTTCTAAGAAATGAAAAAGTATCCTTATGATGTT
TATGTAGTAGCAGGTACCTAAAGCAAGTAATAAAATTTCATATACTTAATGAGATGGTCC
AAATTACATAAGACAAAATATGACGATGATTCTGATTACTAAGATGATGATGAAGATGAT
ATCAATAACGACGATGAACCTGAGCTTGCTTTACAAAGTATTTAAATTAAAGACCCTGTT
AATCGTATTAGAGCTATGTAAAACTCACCACTTGTTGCATATTGGACTGAAAATGGAGAT
GTCACTATTGCTGATTTGTCATCTCGTTATGATATACTTAACTAATGGGATCCAAAAATT
TTAGCTTCAAAACCCAAAAACAATCCTAAAGACAAAGTTTTTACCAAAACTTTCCATAAT
TAAGTTGAAGGTTTTGCTCTTGATTGGAGTCCTATTAAGCCTGGCAGATTGGCTTCAGGT
AGCTGTGATGGCAAAATATTTATTTATAATGCTAAGAATTTTGCCTTTAACGATTGGGAG
AGAGATCAACACCCTTATGTTTACCACGAAGGATCTGTCGAAGATCTTTAGTTCTCTCCT
GTTGAAGAATACAGTCTTGCTTCATGTTCAACTGATGGAACAATTAGAGTAGTTGATTTA
AGAGTAGGTAATAAAAAATAAGCTCAATTACTTGTTAAAGCCCACGAATGTGATGTAAAT
GTTATTTCTTGGAACCACAAGAATCCTTTCCTCATAGCATCAGGAGCAGATGATGGTTGC
TTTAAAGTTTGGGATTTACGTTATCCTGACACTGCATTTACAGAAATTTAATACCATCAA
GAACCAATTACTTCTATACAATGGTAACCAAATGAAGAATCTGTTTTATCAGTTACATCT
GCTGATAACAGACTAACTATTTGGGACTTTTCAGTTGAAAATGATGAAAACGTTGAAGAT
TACGGAGAAGAAATTCCTGATTAACTTATGTTTGTTCATTAAGGTTAATAAGACATGAAA
GAATTAAGATATCATCCTAAATATTATGAAATGATAGTAAGCACAGCTGCAGATGGTTTC
CACATATTCAAACCTGCATTAAACGACGAAGAAGAAAATGAAAAAGAAAAGGAAGATTTA
GAAAATGAAGATTTAAGCAAAATTCCTAAGATAAAAGAATCTGATTTAAATGCTTATTTA
GCTAAAATGAGCTTAAATTGA>TTHERM_00467910(gene)
ATGAGTGACAATAAAAAGATAAGTTAAAAGAGAAAGCTTGAAACTGCTGAAGATGTTTCA
CTTAATATTAAAGAACAAAACTAGAAAAAAAATCCTAATAAGAAGAAAGGGGATTAAGCA
GTAGTTGACGAATTCGAAAAAAATGAAAATTTTGAAGAGGAAGAAGGATCTGAATTAGAA
TTTGAAGATTGTGAAGATGATATAGGTAATTTATACTTTTTTACAGCTTTTTACTAATTC
AGTTTTAAAAAATATGATTTTAATTATGTAGAGTTTATTTATTTATTATGATAAAAATAT
AATTTTGATAAAAATATATTCAAATTACAATAAAACAAATGATTATATTTTAATTATATA
GATGATGAATATGTTGATGAAAAGACATACAAAAAGATTATGTAAGGAAATTTCTAAGAA
GATGAAGAGGAATGGGAAGACGATGGAGATGATGACGATGATGAAAATGAAGAAATTGGT
AATGAAGAAGAAAAATAAGACATAAATGCAAAGAAGAGAAATAAAAAAAATAAAAACTAA
AAAGTTGAATTTATTGATGTTTAATAAAAGCCTTTCATGGGTACTGAAAAGAATTTAGAA
GAAGATGAAATTCTAGATTTCGATAATAAGGCATACGAAATGCTTCATAGAGCTAACACT
GAATGGTAATTTAAATTAACTACTTTTTACATCTTAAATATGAAGCATTTACATATATAA
ACAATCAAACCTCTTGAAAAATTTTTAAGTTTTTAGTTAGTTAAACACACAATTGATAAA
ATAAGTATTTAAGGTTAGTAAAATTCTACATGAAACTATCTATGTAGTTAGTTTTTTAGC
CAAAAATTACAATTGATCTAAAAATACAATAAACAAACAATGCACCTAAACAAAGATATT
AAATTGTTTTAAATATATTTAACAGGCCTTGCTTGTCATGTGATTTTGTAACTGGAGAAC
CTCATAATATTAATAACCCTGGCTTCTAAGAAATGAAAAAGTATCCTTATGATGTTTATG
TAGTAGCAGGTACCTAAAGCAAGTAATAAAATTTCATATACTTAATGAGATGGTCCAAAT
TACATAAGACAAAATATGACGATGATTCTGATTACTAAGATGATGATGAAGATGATATCA
ATAACGACGATGAACCTGAGCTTGCTTTACAAAGTATTTAAATTAAAGACCCTGTTAATC
GTATTAGAGCTATGTAAAACTCACCACTTGTTGCATATTGGACTGAAAATGGAGATGTCA
CTATTGCTGATTTGTCATCTCGTTATGATATACTTAACTAATGGGATCCAAAAATTTTAG
CTTCAAAACCCAAAAACAATCCTAAAGACAAAGTTTTTACCAAAACTTTCCATAATTAAG
TTGAAGGTTTTGCTCTTGATTGGAGTCCTATTAAGCCTGGCAGATTGGCTTCAGGTAGCT
GTGATGGCAAAATATTTATTTATAATGCTAAGAATTTTGCCTTTAACGATTGGGAGAGAG
ATCAACACCCTTATGTTTACCACGAAGGATCTGTCGAAGATCTTTAGTTCTCTCCTGTTG
AAGAATACAGTCTTGCTTCATGTAAAAATAATTTATATTTAGAAAATTAAAAGTTATTAA
ATTTTAACTTAAAATCAAGGTTCAACTGATGGAACAATTAGAGTAGTTGATTTAAGAGTA
GGTAATAAAAAATAAGCTCAATTACTTGTTAAAGCCCACGAATGTGATGTAAATGTTATT
TCTTGGAACCACAAGAATCCTTTCCTCATAGCATCAGGAGCAGATGATGGTTGCTTTAAA
GTTTGGGATTTACGTTATCCTGACACTGCATTTACAGAAATTTAATACCATCAAGAACCA
ATTACTTCTATACAATGGTAACCAAATGAAGAATCTGTTTTATCAGTTACATCTGCTGAT
AACAGACTAACTATTTGGGACTTTTCAGTTGAAAATGATGAAAACGTTGAAGATTACGGA
GAAGAAATTCCTGATTAACTTATGTTTGTTCATTAAGGTAATATATATTTTGAAATTTAA
AATATCATTTTACTAAATCAAAATTCAAAAATTTAGGTTAATAAGACATGAAAGAATTAA
GATATCATCCTAAATATTATGAAATGATAGTAAGCACAGCTGCAGATGGTTTCCACATAT
TCAAACCTGCATTAAACGACGAAGAAGAAAATGAAAAAGAAAAGGAAGATTTAGAAAATG
AAGATTTAAGCAAAATTCCTAAGATAAAAGAATCTGATTTAAATGCTTATTTAGCTAAAA
TGAGCTTAAATTGA>TTHERM_00467910(protein)
MSDNKKISQKRKLETAEDVSLNIKEQNQKKNPNKKKGDQAVVDEFEKNENFEEEEGSELE
FEDCEDDIDDEYVDEKTYKKIMQGNFQEDEEEWEDDGDDDDDENEEIGNEEEKQDINAKK
RNKKNKNQKVEFIDVQQKPFMGTEKNLEEDEILDFDNKAYEMLHRANTEWPCLSCDFVTG
EPHNINNPGFQEMKKYPYDVYVVAGTQSKQQNFIYLMRWSKLHKTKYDDDSDYQDDDEDD
INNDDEPELALQSIQIKDPVNRIRAMQNSPLVAYWTENGDVTIADLSSRYDILNQWDPKI
LASKPKNNPKDKVFTKTFHNQVEGFALDWSPIKPGRLASGSCDGKIFIYNAKNFAFNDWE
RDQHPYVYHEGSVEDLQFSPVEEYSLASCSTDGTIRVVDLRVGNKKQAQLLVKAHECDVN
VISWNHKNPFLIASGADDGCFKVWDLRYPDTAFTEIQYHQEPITSIQWQPNEESVLSVTS
ADNRLTIWDFSVENDENVEDYGEEIPDQLMFVHQGQQDMKELRYHPKYYEMIVSTAADGF
HIFKPALNDEEENEKEKEDLENEDLSKIPKIKESDLNAYLAKMSLN