Identifiers and Description

Gene Model Identifier

TTHERM_00473180

Standard Name

NRK37 (NIMA-Related Kinase )

Aliases

PreTt02218 | 57.m00157 | 3709.m00018

Description

NRK37 Serine/Threonine kinase domain protein; NIMA-Related Kinase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) Protein kinase domain
• ( PF07714 ) Protein tyrosine and serine/threonine kinase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_18311.1	2.9988601762256104e-132
	Description: protein kinase domain-containing protein (649 aa)
Oxytricha	Contig2600.0.g105	2.0004261429631518e-110
	Description: Protein kinase domain
DictyBase	DDB_G0270814	1.0001055852164665e-60
	Description: nek2 on chromosome: 1 position 4847143 to 4848761
Stentor Coeruleus	SteCoe_36025	4.1863939993042314e-51
	Description: None
WormBase	WBGene00021461	4.001501063932074e-49
	Description: locus:nekl-1 status:Partially_confirmed UniProt:Q6AW07 protein_id:CCD69902.1
Tetrahymena borealis	EI9_00570.1	4.001501063932074e-49
	Description: hypothetical protein (964 aa)
SGD	YAR018C	1.9991939848149086e-44
	Description: KIN3 Nonessential serine/threonine protein kinase; possible role in DNA damage response

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00473180(coding)
ATGGGATAGGAATTAAGAGATTTTGAAATTTTAGATAAATTAGGAGAAGGAGCATACAGT
TCTGTTTATAAAGTTAAGCGGTAGTCAGATGGTAAAATATATGCGCTAAAGAGAGTAATG
CTAGGTACATTAACTGAATAAGAAAAACAAAATGCATTAAATGAAGTCAGGATTATTGCT
TCTATCCGTCATCCAAATATAGTGAATTTCAAACAATGCTTTATAGACACACACTTAAAT
TGTTTATGTATTATCATGGAGTATGTAGATAACGGGGATTTACTATCTCATATTAACAAG
CACATTAAGAACGGTACTTACTTTTAAGAGGAAGAGATTTGGAATGTATTAATATAAGTT
GTAAAGGGATTACAGAGCCTCCATTAATTGAGCATTTATCATCGAGACTTGAAAAGTGCA
AATGTGTTTATGAATAAAGACGGTTCTATTAAGTTAGGTGATTTTAATGTTTCTAAAATA
TGTAAATAAGGTCTTTTGTACACTTAGACGGGTACGCCTTATTATGCAAGTCCTGAAGTT
TGGAGGGATTTACCATATGATAGCAAGGCAGATATATGGTCTGTTGGTTGCGTGATATAT
GAAATTTGTGCATTAAAACCCCCATTTAGAGCAGAAAATATGCCTTCTTTGTTTAAAAAA
GTAGTGAAAGGATAGTACCAAAAAATACCTTCTTTTTATTCTCAGTAGTTGAGCTAAATA
ATTAGATAAATGCTTTAAGTGTCTCCTCATTTACGTCCTAGCTGCAAAAAAATATTAGAA
GATGAAGTAGTATAAAAACATATGAATGATAAACATCTTGAAGAACCAGATGAACAAGAA
AGATCTATCCTTATAAATACAATAAAATTTCCTTAGGCTTTTAAAAATAAATATGCTAAA
ATAGAATTTCCAAAACCTAATTATCACCCTGTAAAAATAAGAAAAAGAATTTCAAGCAAC
ACCCGCTTGATAACAACTTTTGATTAAAGTGAATCCATTCTCTAATGCACTAACAAGAGC
ATGATAGAAGAATCATCTCATAAAATGCTCACAGAAAATTCTACTCATTAACCACCTTCA
AGCTAAAGACATCACTCTTAAAGATAAATATAAAACGAAGCTAGTATACTTTCAATGATA
GGTATTGAAAATACTAATATTAATTCTCATAGATAACAAAAGATAAATAAAAAAAATAGC
TATTGTTTATAACAATAAGATAAAATAGAATTATAAGAGGGAATTCAATAAAATAAAAAA
GATTATATAAATATTAACTAGCATGTAAATTATATCTAATAAATTGATAAAATAAGCAAC
ATAGAATTGAATGACTAGCTATTAGCCTCGTCTTAATCAAAAAAAAAAACAAATGCTTCT
CAATAGAATATTAATGGTTTAAATCAACAAAATATTATTCAAGGAAATTAACATAATGAA
GATTTATTTAGTGAATATTAGTCCAAAGCACTTATTATAGACAATTCTAAGAGTGTTTCT
CTTGCAGATGGTGAAAGAAAGATATAAAAATAGAGTATTTCAACAAATGAGAGCCGAAGA
AAATCTATTCATGCTAGATAATCAAGTAGTCTATCATCATAAGTTCAACCAAAAAATTAT
TCTTCAATAAATAAATAAAAATAGCTTTACAAAATATTAAAACAACCAATCAGCATAGTT
AAATAAATTCAACAATAACAATCACCATCTATAAATAATTAAAATGCTTAAACGAATTAG
AATATCATTAATTCATATAATAACAGTTTATTACTAAATTAATCTATAAACAATTAATAA
TATCCATAAAAAAATATTATCAAAAACCAAAGCATTTCATCTGTTTTAAGGGAAAGTTTG
ATTGCTCTAGAGAAAGATATAGCCAAAAGCACGAAAGGCTAAAGAGCCTCTATATAATAA
AACGATAGTAAAGAAATTAGCCATGCTAAAGGAGAATAAATTTAAAGAGATAATGAAAAG
TAAGTCTCAGTAAGTTATTCACGCTCTCACAAAAATTCTTATCACGTAGCACCTGATGGA
GTTCAAAAAAATGAAGAGGATTTTATAAATGGATAGTTGGACTCTATAGCATAATAAAAT
AAAATACAAAGTTATAAAGATAGAAATATTATACCAGATAAAGAAAATTTAAATGATATC
TAATATGTCTCCTAATTATAAACTACTTCTAAAACTACAAAAAACATGAAATAAAATTCT
AAATTAAATTATGAAAAAAGTAAAAGTAGAGAAATTAATCAAAATAGATAAAGCACACAT
TTGTAAGTAATATAAAATGGCTAAGTGAATTAGCACAGAATACCCACGCTATATGAATTA
GATAAATCTCCTGTAGCATATAATGAAGGAAGAAAAAAGAGTAAATCAATTTTCGAAAAA
AACAGTACAACAGTTACAGTCCCTGACTAATACATGAATTTAGAATATAAATATAAAAAA
GAGAAAATGTTAGAAAGCTCCTCAAGACAATAAATAGATAATAATGAAAACACTGAAAAT
ATATTAATAAAAAAACAAATTAAATATTCTGGTGAAACTCCTGAAAAGTTAATAATTCTA
CCAATAATTAACCCTGTTAAAAATACTAAATAAGATAGAAGTATTTCGGTTTAGAGAAAA
TACAGTCCAATATATTCACAAAATAATAACAGGGAAAATATTTTAAATAGGAATGGGCAC
ATATTTTAAGAAAACGATGTTAAAAAGAAGTTACTTTATAATGAAAATGAATAAAAAATA
TTAGATCCAAGTTAAATGCATTTAAATTAAAATAACTTATACATAAATAGTCACAAATAA
AATTACTACCACAATAAGGTCTCTTATTAGCAAACTCCTTTAGCATAAGATAAATATAAT
ATTTAATTAGATATGGAAACAATTGGTAATTATAAAAGAATCCATAGTAATTCAATCAAA
CCTGCACATAAAAATTCTCTATCTCCTTAGAATTACAGAAACAACCAGCAAAGATTAATT
TGA

>TTHERM_00473180(gene)
ATGGGATAGGAATTAAGAGATTTTGAAATTTTAGATAAATTAGGTAAAATTGGATTTGAA
TTTGCATATTTTATACCAGCTCTCATTAGATATAAAGAAAAACTAATTACATTACTGTTA
ATTATTAGGAGAAGGAGCATACAGTTCTGTTTATAAAGTTAAGCGGTAGTCAGATGGTAA
AATATATGCGCTAAAGAGAGTAATGCTAGGTACATTAACTGAATAAGAAAAACAAAATGC
ATTAAATGAAGTCAGGATTATTGCTTCTATCCGTCATCCAAATATAGTGAATTTCAAACA
ATGCTTTATAGACACACACTTAAATTGTTTATGGTAATAGCAAAAAATCCATTACAACAA
GATAACAATTATCATTGAATTAGCAAATATAAATTAAATATTCACAAGAAAAATGATAAT
ATAATTTTAAAAATGTTTACTCAAATCAGAATTTATTCAAATTTTAAAATAATTTTTTCC
AATATTAGTATTAATAATATTTGGTATTAAATAGTATTATCATGGAGTATGTAGATAACG
GGGATTTACTATCTCATATTAACAAGCACATTAAGAACGGTACTTACTTTTAAGAGGAAG
AGATTTGGAATGTATTAATATAAGTAATTATAAATGTTAAATTCTAAATGAAAATTGATT
GTATTATTTATTTTTTAAAGCAAAATATTTTTCTATTTTATATTGAATTTATGAACTTAA
ATAAATTCAGGTTGTAAAGGGATTACAGAGCCTCCATTAATTGAGCATTTATCATCGAGA
CTTGAAAGTTGATTATTTTTTTACTTTTAAACTACTAATAACCATTCAAATCAAATTAAA
AGAAGACAATTATTTTTTAATTTAATTTTGTTGTAATATCTTTAAGAGTGCAAATGTGTT
TATGAATAAAGACGGTTCTATTAAGTTAGGTGATTTTAATGTTTCTAAAATATGTAAATA
AGGTCTTTTGTACACTTAGACGGGTACGCCTTATTATGCAAGGTAATATTAAATGAGTAA
AAATAATTAAGAGTAAACTAATTTGATTGATTATAAATATAGTCCTGAAGTTTGGAGGGA
TTTACCATATGATAGCAAGGCAGATATATGGTCTGTTGGTTGCGTGATATATGAAATTTG
TGCATTAAAACCCCCATTTAGAGCAGAAAATATGCCTTCTTTGTTTAAAAAAGTAGTGAA
AGGTATGATTGTTTTTAGATTATTTGAAAAATTTAATTTTTTTCTTTCTAGGATAGTACC
AAAAAATACCTTCTTTTTATTCTCAGTAGTTGAGCTAAATAATTAGATAAATGCTTTAAG
TGTCTCCTCATTTACGTCCTAGCTGCAGTAAGTTTTTGATATTAATAAAATACCTAAAAA
TAATTTTATCATTATAAAAAAAGAAAAAATATTAGAAGATGAAGTAGTATAAAAACATAT
GAATGATAAACATCTTGAAGAACCAGATGAACAAGAAAGATCTATCCTTATAAATACAAT
AAAATTTCCTTAGGCTTTTAAAAATAAATATGCTAAAATAGAATTTCCAAAACCTAATTA
TCACCCTGTAAAAATAAGAAAAAGAATTTCAAGCAACACCCGCTTGATAACAACTTTTGA
TTAAAGTGAATCCATTCTCTAATGCACTAACAAGAGCATGATAGAAGAATCATCTCATAA
AATGCTCACAGAAAATTCTACTCATTAACCACCTTCAAGCTAAAGACATCACTCTTAAAG
ATAAATATAAAACGAAGCTAGTATACTTTCAATGATAGGTATTGAAAATACTAATATTAA
TTCTCATAGATAACAAAAGATAAATAAAAAAAATAGCTATTGTTTATAACAATAAGATAA
AATAGAATTATAAGAGGGAATTCAATAAAATAAAAAAGATTATATAAATATTAACTAGCA
TGTAAATTATATCTAATAAATTGATAAAATAAGCAACATAGAATTGAATGACTAGCTATT
AGCCTCGTCTTAATCAAAAAAAAAAACAAATGCTTCTCAATAGAATATTAATGGTTTAAA
TCAACAAAATATTATTCAAGGAAATTAACATAATGAAGATTTATTTAGTGAATATTAGTC
CAAAGCACTTATTATAGACAATTCTAAGAGTGTTTCTCTTGCAGATGGTGAAAGAAAGAT
ATAAAAATAGAGTATTTCAACAAATGAGAGCCGAAGAAAATCTATTCATGCTAGATAATC
AAGTAGTCTATCATCATAAGTTCAACCAAAAAATTATTCTTCAATAAATAAATAAAAATA
GCTTTACAAAATATTAAAACAACCAATCAGCATAGTTAAATAAATTCAACAATAACAATC
ACCATCTATAAATAATTAAAATGCTTAAACGAATTAGAATATCATTAATTCATATAATAA
CAGTTTATTACTAAATTAATCTATAAACAATTAATAATATCCATAAAAAAATATTATCAA
AAACCAAAGCATTTCATCTGTTTTAAGGGAAAGTTTGATTGCTCTAGAGAAAGATATAGC
CAAAAGCACGAAAGGCTAAAGAGCCTCTATATAATAAAACGATAGTAAAGAAATTAGCCA
TGCTAAAGGAGAATAAATTTAAAGAGATAATGAAAAGTAAGTCTCAGTAAGTTATTCACG
CTCTCACAAAAATTCTTATCACGTAGCACCTGATGGAGTTCAAAAAAATGAAGAGGATTT
TATAAATGGATAGTTGGACTCTATAGCATAATAAAATAAAATACAAAGTTATAAAGATAG
AAATATTATACCAGATAAAGAAAATTTAAATGATATCTAATATGTCTCCTAATTATAAAC
TACTTCTAAAACTACAAAAAACATGAAATAAAATTCTAAATTAAATTATGAAAAAAGTAA
AAGTAGAGAAATTAATCAAAATAGATAAAGCACACATTTGTAAGTAATATAAAATGGCTA
AGTGAATTAGCACAGAATACCCACGCTATATGAATTAGATAAATCTCCTGTAGCATATAA
TGAAGGAAGAAAAAAGAGTAAATCAATTTTCGAAAAAAACAGTACAACAGTTACAGTCCC
TGACTAATACATGAATTTAGAATATAGTAAATTAATTAATTATTTTAACTTTATCTCTTT
TTCATTTTTTTTGAATAATAAAAGAATATAAAAAAGAGAAAATGTTAGAAAGCTCCTCAA
GACAATAAATAGATAATAATGAAAACACTGAAAATATATTGTAAAATATTAATTTATTTT
CTATTTTTCATATAAAAAATTTAATATTTAAATTAGAATAAAAAAACAAATTAAATATTC
TGGTGAAACTCCTGAAAAGTTAATAATTCTACCAATAATTAACCCTGTTAAAAATACTAA
ATAAGATAGAAGTATTTCGGTTTAGAGAAAATACAGTCCAATATATTCACAAAATAATAA
CAGGGAAAATATTTTAAATAGGAATGGGCACATATTTTAAGAAAACGATGTTAAAAAGAA
GTTACTTTATAATGAAAATGAATAAAAAATATTAGATCCAAGTTAAATGCATTTAAATTA
AAATAACTTATACATAAATAGTCACAAATAAAATTACTACCACAATAAGGTCTCTTATTA
GCAAACTCCTTTAGCATAAGATAAATATAATATTTAATTAGATATGGAAACAATTGGTAA
TTATAAAAGAATCCATAGTAATTCAATCAAACCTGCACATAAAAATTCTCTATCTCCTTA
GAATTACAGAAACAACCAGCAAAGATTAATTTGA

>TTHERM_00473180(protein)
MGQELRDFEILDKLGEGAYSSVYKVKRQSDGKIYALKRVMLGTLTEQEKQNALNEVRIIA
SIRHPNIVNFKQCFIDTHLNCLCIIMEYVDNGDLLSHINKHIKNGTYFQEEEIWNVLIQV
VKGLQSLHQLSIYHRDLKSANVFMNKDGSIKLGDFNVSKICKQGLLYTQTGTPYYASPEV
WRDLPYDSKADIWSVGCVIYEICALKPPFRAENMPSLFKKVVKGQYQKIPSFYSQQLSQI
IRQMLQVSPHLRPSCKKILEDEVVQKHMNDKHLEEPDEQERSILINTIKFPQAFKNKYAK
IEFPKPNYHPVKIRKRISSNTRLITTFDQSESILQCTNKSMIEESSHKMLTENSTHQPPS
SQRHHSQRQIQNEASILSMIGIENTNINSHRQQKINKKNSYCLQQQDKIELQEGIQQNKK
DYININQHVNYIQQIDKISNIELNDQLLASSQSKKKTNASQQNINGLNQQNIIQGNQHNE
DLFSEYQSKALIIDNSKSVSLADGERKIQKQSISTNESRRKSIHARQSSSLSSQVQPKNY
SSINKQKQLYKILKQPISIVKQIQQQQSPSINNQNAQTNQNIINSYNNSLLLNQSINNQQ
YPQKNIIKNQSISSVLRESLIALEKDIAKSTKGQRASIQQNDSKEISHAKGEQIQRDNEK
QVSVSYSRSHKNSYHVAPDGVQKNEEDFINGQLDSIAQQNKIQSYKDRNIIPDKENLNDI
QYVSQLQTTSKTTKNMKQNSKLNYEKSKSREINQNRQSTHLQVIQNGQVNQHRIPTLYEL
DKSPVAYNEGRKKSKSIFEKNSTTVTVPDQYMNLEYKYKKEKMLESSSRQQIDNNENTEN
ILIKKQIKYSGETPEKLIILPIINPVKNTKQDRSISVQRKYSPIYSQNNNRENILNRNGH
IFQENDVKKKLLYNENEQKILDPSQMHLNQNNLYINSHKQNYYHNKVSYQQTPLAQDKYN
IQLDMETIGNYKRIHSNSIKPAHKNSLSPQNYRNNQQRLI