Identifiers and Description

Gene Model Identifier

TTHERM_00483400

Standard Name

CTH64 (CaTHepsin 64)

Aliases

PreTt06274 | 58.m00246 | 3719.m00100

Description

CTH64 papain family cysteine protease; Peptidase C1A

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• obsolete integral component of mitochondrial membrane (IEA) | GO:0032592
• THO complex (IEA) | GO:0000347

Molecular Function

• 11-deoxycorticosterone binding (IEA) | GO:1903878
• 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity (IEA) | GO:0008413
• cytoskeletal anchor activity (IEA) | GO:0008093
• delta-type opioid receptor binding (IEA) | GO:0031850
• dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity (IEA) | GO:0106073
• fimbrial usher porin activity (IEA) | GO:0015473
• G protein-coupled serotonin receptor binding (IEA) | GO:0031821
• high-affinity secondary active nitrite transmembrane transporter activity (IEA) | GO:0015513
• interleukin-10 receptor binding (IEA) | GO:0005141
• L-gamma-glutamyl-L-propargylglycine hydroxylase activity (IEA) | GO:0062148
• lipopolysaccharide heptosyltransferase activity (IEA) | GO:0008920
• mercury ion transmembrane transporter activity (IEA) | GO:0015097
• nitrite efflux transmembrane transporter activity (IEA) | GO:0015514
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• phosphatidylserine decarboxylase activity (IEA) | GO:0004609
• sphingomyelin phosphodiesterase activity (IEA) | GO:0004767
• tumor necrosis factor receptor binding (IEA) | GO:0005164
• zinc efflux active transmembrane transporter activity (IEA) | GO:0015341

Biological Process

• auditory receptor cell fate commitment (IEA) | GO:0009912
• cell wall modification involved in fruit ripening (IEA) | GO:0009829
• cytoplasmic actin-based contraction involved in forward cell motility (IEA) | GO:0060328
• cytoplasmic actin-based contraction involved in rearward cell motility (IEA) | GO:0060329
• galactose to glucose-1-phosphate metabolic process (IEA) | GO:0061612
• glycolytic process from glycerol (IEA) | GO:0061613
• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• hexasaccharide transport (IEA) | GO:2001102
• macrophage derived foam cell differentiation (IEA) | GO:0010742
• maltohexaose transport (IEA) | GO:2001103
• muscle contraction (IEA) | GO:0006936
• negative regulation of complement-dependent cytotoxicity (IEA) | GO:1903660
• negative regulation of epithelial cell-cell adhesion involved in epithelium migration (IEA) | GO:1903682
• negative regulation of glyoxylate cycle (IEA) | GO:2000875
• negative regulation of L-glutamine biosynthetic process (IEA) | GO:0062133
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• negative regulation of phytoalexin metabolic process (IEA) | GO:0052321
• obsolete induction by virus of host cell-cell fusion (IEA) | GO:0006948
• ommochrome biosynthetic process (IEA) | GO:0006727
• phagocytosis (IEA) | GO:0006909
• pigment metabolic process involved in pigment accumulation (IEA) | GO:0043475
• plant-type cell wall modification (IEA) | GO:0009827
• positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction (IEA) | GO:0052330
• positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
• positive regulation of cap-independent translational initiation (IEA) | GO:1903679
• positive regulation of flower development (IEA) | GO:0009911
• positive regulation of forebrain neuron differentiation (IEA) | GO:2000979
• positive regulation of L-leucine biosynthetic process (IEA) | GO:2001278
• positive regulation of peroxisome proliferator activated receptor signaling pathway (IEA) | GO:0035360
• positive regulation of response to water deprivation (IEA) | GO:1902584
• positive regulation of stress response to copper ion (IEA) | GO:1903855
• positive regulation of tumor necrosis factor biosynthetic process (IEA) | GO:0042535
• positive regulation of wound healing, spreading of epidermal cells (IEA) | GO:1903691
• propan-2-ol biosynthetic process (IEA) | GO:1902640
• protein localization to old growing cell tip (IEA) | GO:1903858
• pteridine biosynthetic process (IEA) | GO:0006728
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
• regulation of complement-dependent cytotoxicity (IEA) | GO:1903659
• regulation of dendrite extension (IEA) | GO:1903859
• regulation of inner ear receptor cell differentiation (IEA) | GO:2000980
• regulation of macrophage derived foam cell differentiation (IEA) | GO:0010743
• regulation of muscle cell chemotaxis toward tendon cell (IEA) | GO:2001281
• regulation of phosphatidylcholine biosynthetic process (IEA) | GO:2001245
• regulation of sprouting angiogenesis (IEA) | GO:1903670
• regulation of unsaturated fatty acid biosynthetic process (IEA) | GO:2001279
• regulation of wound healing, spreading of epidermal cells (IEA) | GO:1903689
• tertiary alcohol biosynthetic process (IEA) | GO:1902645
• vitamin A metabolic process (IEA) | GO:0006776

Domains

• ( PF00112 ) Papain family cysteine protease
• ( PF08246 ) Cathepsin propeptide inhibitor domain (I29)

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00483400(coding)
ATGAAATTTATATTTGGTGCTTGCTTATCCTTAATATTAACTAGTCTTATTGGATTAGGT
TATCTGATTTATAAGGATACTCCTTAGAGTTAGTTTAATAAAATTAAGTCTGAATTCGAA
AATTTCAAGAATAGATATAACTTGGAGTTCAATGATATCTAGGAAGAGTAGTACAGACTG
TTTGTCTTTCATGAAAATTTCAAATAAATAGAACTAGATAATATGAATTCTGATAATGGT
TTCATTTCTGGTATCAATAAATTTTCACATTTAACAAAAGAAGAATTCAAAGCTAAATAT
TTGAATCGTCCTTAAAGACCTGCTTCAGAAATGAAAACCAATTCAATTTTATCTTCTTAA
TAAAAAACTGACGAAAAACTTCCAGAAAGTGTAGACTGGAGAAAGTTAGGTGCCGTTTCA
CCAGTTAGAGATCAAGGCAATTGTGGTTCTTGTTATGCGTTTGCTTCTACAGGCGCTCTT
GAAGGGTTGTACTAAATAAAAACAGGAAAGTTAGAAGTTTTTTCGCCTTAATATATTGTT
GATTGTGCTAAACATTAGTTTTCAAGGGGAGGTTGTCATGGAGGATATTCTTCTGGTGTA
TTCACTTTCGTTAAAGAAAATGGGATGAATTTAGAATCAAGATACCCTTATAAAGGTGAA
GAAAATGACAAATGTTTAAATTAAGAAACTATCAAGTTTGTTAATGACTTTAAATTAATT
AATTAGGGAGATTGCTAAGAGATAGAGAGAGTGCTTTTTAAACAGCCTGTATCAATTTCT
CTTGATGCTGAGAAAGTGCAACATTATTAATCAGGTATTCTTAAGTAGTGTTCAGATACA
ATTAATATAAATCACGAAGTACTTGCCGTGGGTTACACATCTGACTATTTTATCCTAAAA
AACTCTTGGGGTTCTGATTGGGGTATTGATGGATACTTCTATGTTTCTAAAAATAATAAC
TGTGGTACTTGTGATGGGGCTTCATACCCAACTTTATGA

>TTHERM_00483400(gene)
CAAATTGATAAATATTATTAATAAAAAAAATATATTTAAGTTTGGATCTTACAAAAAACT
TATGAAATTTATATTTGGTGCTTGCTTATCCTTAATATTAACTAGTCTTATTGGATTAGG
TTATCTGATTTATAAGGATACTCCTTAGAGTTAGTTTAATAAAATTAAGTCTGAATTCGA
AAATTTCAAGAATAGATATAACTTGGAGTTCAATGATATCTAGGAAGAGTAGTACAGACT
GTTTGTCTTTCATGAAAATTTCAAATAAATAGAACTAGATAATATGAATTCTGATAATGG
TTTCATTTCTGGTATCAATAAATTTTCACATTTAACAAAAGAAGAATTCAAAGCTAAATA
TTTGAATCGTCCTTAAAGACCTGCTTCAGAAATGAAAACCAATTCAATTTTATCTTCTTA
ATAAAAAACTGACGAAAAACTTCCAGAAAGTGTAGACTGGAGAAAGTTAGGTGCCGTTTC
ACCAGTTAGAGATCAAGGCAATTGTGGTTCTTGTTATGCGTTTGCTTCTACAGGCGCTCT
TGAAGGGTTGTACTAAATAAAAACAGGAAAGTTAGAAGTTTTTTCGCCTTAATATATTGT
TGATTGTGCTAAACATTAGTTTTCAAGGGGAGGTTGTCATGGAGGATATTCTTCTGGTGT
ATTCACTTTCGTTAAAGAAAATGGGATGAATTTAGAATCAAGATACCCTTATAAAGGTGA
AGAAAATGACAAATGTTTAAATTAAGAAACTATCAAGTTTGTTAATGACTTTAAATTAAT
TAATTAGGGAGATTGCTAAGAGATAGAGAGAGTGCTTTTTAAACAGCCTGTATCAATTTC
TCTTGATGCTGAGAAAGTGCAACATTATTAATCAGGTATTCTTAAGTAGTGTTCAGATAC
AATTAATATAAATCACGAAGTACTTGCCGTGGGTTACACATCTGACTATTTTATCCTAAA
AAACTCTTGGGGTTCTGATTGGGGTATTGATGGATACTTCTATGTTTCTAAAAATAATAA
CTGTGGTACTTGTGATGGGGCTTCATACCCAACTTTATGAGTTTATCTTGAGATAAAATA
AAAGAACTTACTTTTTTATGTTTTAATTTGTTTAGTATAATTCATTTATTTGCTCATGAT
TATATTTAAATTATATTAATTATTTAGTTTAAATATTTAATGTTATTTATAAATTTCATC
TAATGTTTAATTTGTAAAAA

>TTHERM_00483400(protein)
MKFIFGACLSLILTSLIGLGYLIYKDTPQSQFNKIKSEFENFKNRYNLEFNDIQEEQYRL
FVFHENFKQIELDNMNSDNGFISGINKFSHLTKEEFKAKYLNRPQRPASEMKTNSILSSQ
QKTDEKLPESVDWRKLGAVSPVRDQGNCGSCYAFASTGALEGLYQIKTGKLEVFSPQYIV
DCAKHQFSRGGCHGGYSSGVFTFVKENGMNLESRYPYKGEENDKCLNQETIKFVNDFKLI
NQGDCQEIERVLFKQPVSISLDAEKVQHYQSGILKQCSDTININHEVLAVGYTSDYFILK
NSWGSDWGIDGYFYVSKNNNCGTCDGASYPTL