Identifiers and Description

Gene Model Identifier

TTHERM_00486630

Standard Name

CTH105 (CaTHepsin 105)

Aliases

PreTt19594 | 59.m00232 | 3680.m00089

Description

CTH105 papain family cysteine protease; Peptidase C1A

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• obsolete integral component of mitochondrial membrane (IEA) | GO:0032592
• THO complex (IEA) | GO:0000347

Molecular Function

• 11-deoxycorticosterone binding (IEA) | GO:1903878
• 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity (IEA) | GO:0008413
• cytoskeletal anchor activity (IEA) | GO:0008093
• delta-type opioid receptor binding (IEA) | GO:0031850
• dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity (IEA) | GO:0106073
• fimbrial usher porin activity (IEA) | GO:0015473
• G protein-coupled serotonin receptor binding (IEA) | GO:0031821
• high-affinity secondary active nitrite transmembrane transporter activity (IEA) | GO:0015513
• interleukin-10 receptor binding (IEA) | GO:0005141
• L-gamma-glutamyl-L-propargylglycine hydroxylase activity (IEA) | GO:0062148
• lipopolysaccharide heptosyltransferase activity (IEA) | GO:0008920
• mercury ion transmembrane transporter activity (IEA) | GO:0015097
• nitrite efflux transmembrane transporter activity (IEA) | GO:0015514
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• phosphatidylserine decarboxylase activity (IEA) | GO:0004609
• sphingomyelin phosphodiesterase activity (IEA) | GO:0004767
• tumor necrosis factor receptor binding (IEA) | GO:0005164
• zinc efflux active transmembrane transporter activity (IEA) | GO:0015341

Biological Process

• auditory receptor cell fate commitment (IEA) | GO:0009912
• cell wall modification involved in fruit ripening (IEA) | GO:0009829
• cytoplasmic actin-based contraction involved in forward cell motility (IEA) | GO:0060328
• cytoplasmic actin-based contraction involved in rearward cell motility (IEA) | GO:0060329
• galactose to glucose-1-phosphate metabolic process (IEA) | GO:0061612
• glycolytic process from glycerol (IEA) | GO:0061613
• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• hexasaccharide transport (IEA) | GO:2001102
• macrophage derived foam cell differentiation (IEA) | GO:0010742
• maltohexaose transport (IEA) | GO:2001103
• muscle contraction (IEA) | GO:0006936
• negative regulation of complement-dependent cytotoxicity (IEA) | GO:1903660
• negative regulation of epithelial cell-cell adhesion involved in epithelium migration (IEA) | GO:1903682
• negative regulation of glyoxylate cycle (IEA) | GO:2000875
• negative regulation of L-glutamine biosynthetic process (IEA) | GO:0062133
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• negative regulation of phytoalexin metabolic process (IEA) | GO:0052321
• obsolete induction by virus of host cell-cell fusion (IEA) | GO:0006948
• ommochrome biosynthetic process (IEA) | GO:0006727
• phagocytosis (IEA) | GO:0006909
• pigment metabolic process involved in pigment accumulation (IEA) | GO:0043475
• plant-type cell wall modification (IEA) | GO:0009827
• positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction (IEA) | GO:0052330
• positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
• positive regulation of cap-independent translational initiation (IEA) | GO:1903679
• positive regulation of flower development (IEA) | GO:0009911
• positive regulation of forebrain neuron differentiation (IEA) | GO:2000979
• positive regulation of L-leucine biosynthetic process (IEA) | GO:2001278
• positive regulation of peroxisome proliferator activated receptor signaling pathway (IEA) | GO:0035360
• positive regulation of response to water deprivation (IEA) | GO:1902584
• positive regulation of stress response to copper ion (IEA) | GO:1903855
• positive regulation of tumor necrosis factor biosynthetic process (IEA) | GO:0042535
• positive regulation of wound healing, spreading of epidermal cells (IEA) | GO:1903691
• propan-2-ol biosynthetic process (IEA) | GO:1902640
• protein localization to old growing cell tip (IEA) | GO:1903858
• pteridine biosynthetic process (IEA) | GO:0006728
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
• regulation of complement-dependent cytotoxicity (IEA) | GO:1903659
• regulation of dendrite extension (IEA) | GO:1903859
• regulation of inner ear receptor cell differentiation (IEA) | GO:2000980
• regulation of macrophage derived foam cell differentiation (IEA) | GO:0010743
• regulation of muscle cell chemotaxis toward tendon cell (IEA) | GO:2001281
• regulation of phosphatidylcholine biosynthetic process (IEA) | GO:2001245
• regulation of sprouting angiogenesis (IEA) | GO:1903670
• regulation of unsaturated fatty acid biosynthetic process (IEA) | GO:2001279
• regulation of wound healing, spreading of epidermal cells (IEA) | GO:1903689
• tertiary alcohol biosynthetic process (IEA) | GO:1902645
• vitamin A metabolic process (IEA) | GO:0006776

Domains

• ( PF00112 ) Papain family cysteine protease
• ( PF08246 ) Cathepsin propeptide inhibitor domain (I29)

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00486630(coding)
ATGAATTTAACTTAAAAAATTCTTGTTAGTGTAGCAGTTTTAGGTGTTTTCTTGCTCACC
TTAAACTATGTTATTGATCATAAAACTGATGATGAAATTAAATTTATGCTTAGAAAGTCT
ATTGAAAGAGCTTTTAAGAATTTCAAGGTTAAATACGCTAAAACTTATAAAGATGATACT
GAAGAATAATACAGATTCTCTGTCTTTACAAACAACTACGTAGAAATCTATAGACACAAT
AAATTTTTAGTCTTTTCTAAGGTAGGCGTCAATTAATTCGCTGATCTTACCCATGAAGAA
TTCAAAGCTTTATATACTGGTCATAAACACTCAAAAGATGATGACGATGATGATAATAAA
AATAAACAACCTCATCTCCCAACTGATAACTTACCTGCCTCTTTCGATTGGAGAGATAAG
GGTGCTATTACTCCAGTTAAAGTCCAAAACGGATGTGGTGGCTGCTGGGCCTTTTCCACT
GTACAAAGTATCGAAGGTCTTTACTTTTTGAAAACTGGTAAATTAGAATCCCTTTCTACC
TAATAAGTAATTGATTGTTGCAGAATCGATGAAAGTGGCTGTCTTGGTGGTGATCCTGAA
CCTGCTTTCAGATGTATTTAAAATAATGGTGGTATCATGACTGAAACAGAATATCCTTAT
ATTGCCAAGCAACAATCTTGCAAATTTGATGAAGACAAGCCTACCTTCTAAATCGGAGGA
TATATTGATGTCCCTTCTGATTAATCTTAAGTTAAGGCTGCACTCCTTATCCAACCTCTT
TCAATTTGTTTGAATAGTTCTGATACCTCATTCAAATATTACAAATCAGGTGTCATTACT
GAGTGCGAAGATGGTCCTTATGATGGTCCCGATCACTGCCTTTTACTTGTAGGTTATGGT
CATGATGAAGAATTGAAAGTTGATTATTGGTTAATTAAAAATCAATGGGGTACAACTTGG
GGTGAAGAAGGTTACGTTAGAATTATTAGAGATGATAATGATCATAAGGGTCCTGGTAAG
TGCTTCGTTGTTGCTGAAGTTCGTTATCCTATTGCTAAAAACACTACTGCCTCAGCTTTT
TGA

>TTHERM_00486630(gene)
GCATATATAGATTTTTGATTTAGACATAATTTTTAATACAAAAAATTAAATAAACTTAAA
TTATATTGAGAATATAAAGAGATGAATTTAACTTAAAAAATTCTTGTTAGTGTAGCAGTT
TTAGGTGTTTTCTTGCTCACCTTAAACTATGTTATTGATCATAAAACTGATGATGAAATT
AAATTTATGCTTAGAAAGTCTATTGAAAGAGCTTTTAAGAATTTCAAGGTTAAATACGCT
AAAACTTATAAAGATGATACTGAAGAATAATACAGATTCTCTGTCTTTACAAACAACTAC
GTAGAAATCTATAGACACAATAAATTTTTAGTCTTTTCTAAGGTAGGCGTCAATTAATTC
GCTGATCTTACCCATGAAGAATTCAAAGCTTTATATACTGGTCATAAACACTCAAAAGAT
GATGACGATGATGATAATAAAAATAAACAACCTCATCTCCCAACTGATAACTTACCTGCC
TCTTTCGATTGGAGAGATAAGGGTGCTATTACTCCAGTTAAAGTCCAAAACGGATGTGGT
GGCTGCTGGGCCTTTTCCACTGTACAAAGTATCGAAGGTCTTTACTTTTTGAAAACTGGT
AAATTAGAATCCCTTTCTACCTAATAAGTAATTGATTGTTGCAGAATCGATGAAAGTGGC
TGTCTTGGTGGTGATCCTGAACCTGCTTTCAGATGTATTTAAAATAATGGTGGTATCATG
ACTGAAACAGAATATCCTTATATTGCCAAGCAACAATCTTGCAAATTTGATGAAGACAAG
CCTACCTTCTAAATCGGAGGATATATTGATGTCCCTTCTGATTAATCTTAAGTTAAGGCT
GCACTCCTTATCCAACCTCTTTCAATTTGTTTGAATAGTTCTGATACCTCATTCAAATAT
TACAAATCAGGTGTCATTACTGAGTGCGAAGATGGTCCTTATGATGGTCCCGATCACTGC
CTTTTACTTGTAGGTTATGGTCATGATGAAGAATTGAAAGTTGATTATTGGTTAATTAAA
AATCAATGGGGTACAACTTGGGGTGAAGAAGGTTACGTTAGAATTATTAGAGATGATAAT
GATCATAAGGGTCCTGGTAAGTGCTTCGTTGTTGCTGAAGTTCGTTATCCTATTGCTAAA
AACACTACTGCCTCAGCTTTTTGAGTTAAAAATAAAAACAAAAAAACGAATTTAAGTTTT
GATTTATAAAAACTATAATAAAATAATTTATATCAAAATAATGCAAATCTTAATAGAATT
TTGTATTTAGATTTATTCATTCAATCTATAAAAGTATATTTTTCAATTTATCCAAAATTT
AGTTAAAAAATAAACA

>TTHERM_00486630(protein)
MNLTQKILVSVAVLGVFLLTLNYVIDHKTDDEIKFMLRKSIERAFKNFKVKYAKTYKDDT
EEQYRFSVFTNNYVEIYRHNKFLVFSKVGVNQFADLTHEEFKALYTGHKHSKDDDDDDNK
NKQPHLPTDNLPASFDWRDKGAITPVKVQNGCGGCWAFSTVQSIEGLYFLKTGKLESLST
QQVIDCCRIDESGCLGGDPEPAFRCIQNNGGIMTETEYPYIAKQQSCKFDEDKPTFQIGG
YIDVPSDQSQVKAALLIQPLSICLNSSDTSFKYYKSGVITECEDGPYDGPDHCLLLVGYG
HDEELKVDYWLIKNQWGTTWGEEGYVRIIRDDNDHKGPGKCFVVAEVRYPIAKNTTASAF