Identifiers and Description

Gene Model Identifier

TTHERM_00486790

Standard Name

DRP1 (Dynamin Related Protein 1)

Aliases

PreTt19610 | 59.m00248 | 3680.m00105

Description

DRP1 dynamin central region family protein; Dynamin-related protein (DRP); localized to endocytic sites; essential for growth; DRP1 expression required for clathrin-mediated endocytosis; one of 8 DRP genes in Tetrahymena; Dynamin

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• ciliary basal body (IDA) | GO:0036064
• clathrin-coated pit (IDA) | GO:0005905

Biological Process

• clathrin-dependent endocytosis (IMP) | GO:0072583

Domains

• ( PF00350 ) Dynamin family
• ( PF01031 ) Dynamin central region
• ( PF02212 ) Dynamin GTPase effector domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16276403: Elde NC, Morgan G, Winey M, Sperling L, Turkewitz AP (2005) Elucidation of clathrin-mediated endocytosis in tetrahymena reveals an evolutionarily convergent recruitment of dynamin. PLoS genetics 1(5):e52

Sequences

>TTHERM_00486790(coding)
ATGGCTGAGCAAGAAAGTTCATTTTAGGGATCAGGTCTTTTTGATAACCTTAGAAAGTTA
ATTAACGTCATCGATGAATTAAGAGATGTCGGTTTACAACAATATATTAGATTGCCTAGA
ATCGCAGTTATTGGTTCTTAATCATCTGGTAAATCATCTCTTCTCGAAAGTATCGTTGGT
ATCGATTTCTTGCCAAGAGGTTCTGGTGTAGTTACTCGTAGACCTTTAGAACTCAGATTA
GTTCATGTGCCTCCCAATGAAAGATAAATCAAGCCATATGCTATTTTCGATGTTGATAAA
TCAAAGAAGTGGGAAAACTTTGATTAGGTTAGATAACAAATCGATTTCTTAACTGACCAA
GTTGCAGGTAAGAGAAAGAAAATTATCAATGACCCTATCGTATTGACTATTTACTCAAAT
GATGTTATCGATTTGACAATTATTGATTTGCCTGGTATTACAAGAATTCCCTTAAAAGAT
TCAGACCAATAAGAAGATATCGAAAAAGTTACTAAAGATATGGCTTACTCATACATAAAA
GATGAAAGAACAATTATTTTGTGTGTTGTTCCTGGTAACTAGGATATTTCTAACTCCGAT
GGTCTCTAATTAGCTAGAGAAGTAGACAGAGAAGGCAATAGAACAATTGGTGTTGTTACA
AAACTTGATATCATGGATGCTGATACTGATGCAAGAAAAATGATCATGGGTCTTGAAATT
CCTTTGAAATTAGGATATGTTGGTGTCAAGGGTAGATCTCAAAAGGATATTAATGACAAT
AAGAGAGTTTCTAAAGCTCTTGACGAAGAAAGACTTTTCTTTGCTTAGCATAAAGTATAC
TCAACTATGGATCCTAAGTTCTTAGGTACTAAAGCTTTGACTAATAAGTTATCAAGTGTG
CTTTTCTATCACATTAGAAATATTTTACCTGCTATCGTCAAGGAAATTAAAGATAAATTG
AAAGAATGTGAAGATAGACTTAAAGACTTGGGTCCCTCTCTTCCAAGAGAACAAAAAGAT
AAAATGCAACTTATCTGGACCATGATTACTGATTTTACTGAAAACTTTAAAAATACAATT
AAGGGTAAATACGATCAAAGACGTTCTAATATTAATACAGAATTATCTGGTGGTGCAGTT
ATTAAGATGATGTTCAATGAGCTTTATGAAGATTTCATTTAAAAAACCTTTAGAGCAACT
AGAGAATATAGCGATAAAGATATTTAAACAGCTATTTAATTGCATTAAGGTGATTCTATT
CCAGGTTTCCCCTCAATAGATGCTTTCTTATATTTAATTAATCCTCAATTAGAAAAGCTA
AAAGACCCTGCCTTTGAATGCTTAACTTAATGCTACAATTATTTGGAAGGTTTAGCTAAT
AAGATTTTGAAGAAAATATTCTCAAGATTCCCCACTGTTATGGACGAAATTGCAGATATT
ACAAGCAGAGTGCTTCAAGCTTAAAGAGATTAAGCAAAAGAAGTTGTTAACAATATTATT
GAATCTGAATAAGGTTACCTTTTCACTAATGATTTAGGCTATCTTGCTCACAGAACTCAT
TTGATTCCAGCTCAAGAATCTGGTAAAGAAGGTTAACAATAGATAGATGCTGAAAAAGCT
TTTATTAATGAATTGAGATCTAGAGTAGACGTTTACTTCAATATCGTTGTCAGAAATGTA
AGAGACTCTATTCCTAAGGCTATTGGTTTCTTCTTAGTTAAGGCTGCTTAAGAATAATTG
TAATATTAATTATATAATGAAATTATGAGAAGTGAAGATTCTCTTGGTAGCATTGCAGAA
CCTGCCAACATCGCAGAAGAAAGAGATACACTCAATAAAACTATCGAAGTTCTTCAAAAG
GCTCATAGAGTTATTAAGAGAGATCCTGATCTTCAACCCAGATATGATGGATAGAATCCT
TAAAAGCAAGTTGTTTGA

>TTHERM_00486790(gene)
AAAAGCATAGATTCATCAAAAAAGCAAAAATAAAATATAAAAAATTAAATAAAAGCTAAA
CAATTTCATCAAATAAAAAAGTAAAGCAAAATTTAGAAATAAAGATAAATGGCTGAGCAA
GAAAGTTCATTTTAGGGATCAGGTCTTTTTGATAACCTTAGAAAGTTAATTAACGTCATC
GATGAATTAAGAGATGTCGGTTTACAACAATATATTAGATTGCCTAGAATCGCAGTTATT
GGTTCTTAATCATCTGGTAAATCATCTCTTCTCGAAAGTATCGTTGGTATCGATTTCTTG
CCAAGAGGTTCTGGTGTAGTTACTCGTAGACCTTTAGAACTCAGATTAGTTCATGTGCCT
CCCAATGAAAGATAAATCAAGCCATATGCTATTTTCGATGTTGATAAATCAAAGAAGTGG
GAAAACTTTGATTAGGTTAGATAACAAATCGATTTCTTAACTGACCAAGTTGCAGGTAAG
AGAAAGAAAATTATCAATGACCCTATCGTATTGACTATTTACTCAAATGATGTTATCGAT
TTGACAATTATTGATTTGCCTGGTATTACAAGAATTCCCTTAAAAGATTCAGACCAATAA
GAAGATATCGAAAAAGTTACTAAAGATATGGCTTACTCATACATAAAAGATGAAAGAACA
ATTATTTTGTGTGTTGTTCCTGGTAACTAGGATATTTCTAACTCCGATGGTCTCTAATTA
GCTAGAGAAGTAGACAGAGAAGGCAATAGAACAATTGGTGTTGTTACAAAACTTGATATC
ATGGATGCTGATACTGATGCAAGAAAAATGATCATGGGTCTTGAAATTCCTTTGAAATTA
GGATATGTTGGTGTCAAGGGTAGATCTCAAAAGGATATTAATGACAATAAGAGAGTTTCT
AAAGCTCTTGACGAAGAAAGACTTTTCTTTGCTTAGCATAAAGTATACTCAACTATGGAT
CCTAAGTTCTTAGGTACTAAAGCTTTGACTAATAAGTTATCAAGTGTGCTTTTCTATCAC
ATTAGAAATATTTTACCTGCTATCGTCAAGGAAATTAAAGATAAATTGAAAGAATGTGAA
GATAGACTTAAAGACTTGGGTCCCTCTCTTCCAAGAGAACAAAAAGATAAAATGCAACTT
ATCTGGACCATGATTACTGATTTTACTGAAAACTTTAAAAATACAATTAAGGGTAAATAC
GATCAAAGACGTTCTAATATTAATACAGAATTATCTGGTGGTGCAGTTATTAAGATGATG
TTCAATGAGCTTTATGAAGATTTCATTTAAAAAACCTTTAGAGCAACTAGAGAATATAGC
GATAAAGATATTTAAACAGCTATTTAATTGCATTAAGGTGATTCTATTCCAGGTTTCCCC
TCAATAGATGCTTTCTTATATTTAATTAATCCTCAATTAGAAAAGCTAAAAGACCCTGCC
TTTGAATGCTTAACTTAATGCTACAATTATTTGGAAGGTTTAGCTAATAAGATTTTGAAG
AAAATATTCTCAAGATTCCCCACTGTTATGGACGAAATTGCAGATATTACAAGCAGAGTG
CTTCAAGCTTAAAGAGATTAAGCAAAAGAAGTTGTTAACAATATTATTGAATCTGAATAA
GGTTACCTTTTCACTAATGATTTAGGCTATCTTGCTCACAGAACTCATTTGATTCCAGCT
CAAGAATCTGGTAAAGAAGGTTAACAATAGATAGATGCTGAAAAAGCTTTTATTAATGAA
TTGAGATCTAGAGTAGACGTTTACTTCAATATCGTTGTCAGAAATGTAAGAGACTCTATT
CCTAAGGCTATTGGTTTCTTCTTAGTTAAGGCTGCTTAAGAATAATTGTAATATTAATTA
TATAATGAAATTATGAGAAGTGAAGATTCTCTTGGTAGCATTGCAGAACCTGCCAACATC
GCAGAAGAAAGAGATACACTCAATAAAACTATCGAAGTTCTTCAAAAGGCTCATAGAGTT
ATTAAGAGAGATCCTGATCTTCAACCCAGATATGATGGATAGAATCCTTAAAAGCAAGTT
GTTTGAAGAATATGATTATTCAATGAGGATTTTAATATTTCTAAAATAATTACCAAAACT
AAAAATCTAAATTATAAAATAAAAATCCAAATAATAAAATATAGAATAAATAAGCAATAT
CTCTAGTTAAATTTAATTTTGTTAAATCGTTTGCTCAAGAATATCTGTCTTAAATATAAT
ATGTTAACTTAAATCAGTACATTTAGTGTATTTCCATGTCAAATATGTATCCCAGCAATA
TCTATAAATGTACAAGCT

>TTHERM_00486790(protein)
MAEQESSFQGSGLFDNLRKLINVIDELRDVGLQQYIRLPRIAVIGSQSSGKSSLLESIVG
IDFLPRGSGVVTRRPLELRLVHVPPNERQIKPYAIFDVDKSKKWENFDQVRQQIDFLTDQ
VAGKRKKIINDPIVLTIYSNDVIDLTIIDLPGITRIPLKDSDQQEDIEKVTKDMAYSYIK
DERTIILCVVPGNQDISNSDGLQLAREVDREGNRTIGVVTKLDIMDADTDARKMIMGLEI
PLKLGYVGVKGRSQKDINDNKRVSKALDEERLFFAQHKVYSTMDPKFLGTKALTNKLSSV
LFYHIRNILPAIVKEIKDKLKECEDRLKDLGPSLPREQKDKMQLIWTMITDFTENFKNTI
KGKYDQRRSNINTELSGGAVIKMMFNELYEDFIQKTFRATREYSDKDIQTAIQLHQGDSI
PGFPSIDAFLYLINPQLEKLKDPAFECLTQCYNYLEGLANKILKKIFSRFPTVMDEIADI
TSRVLQAQRDQAKEVVNNIIESEQGYLFTNDLGYLAHRTHLIPAQESGKEGQQQIDAEKA
FINELRSRVDVYFNIVVRNVRDSIPKAIGFFLVKAAQEQLQYQLYNEIMRSEDSLGSIAE
PANIAEERDTLNKTIEVLQKAHRVIKRDPDLQPRYDGQNPQKQVV