Identifiers and Description

Gene Model Identifier

TTHERM_00487020

Standard Name

PRS1 (Prolyl-tRNA synthetase 1)

Aliases

PreTt19633 | 59.m00271 | 3680.m00128

Description

PRS1 prolyl-tRNA synthetase protein putative; prolyl-tRNA synthetase family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cytoplasm (IEA) | GO:0005737

Molecular Function

• aminoacyl-tRNA ligase activity (IEA) | GO:0004812
• ATP binding (IEA) | GO:0005524
• nucleotide binding (IEA) | GO:0000166
• proline-tRNA ligase activity (IEA) | GO:0004827

Biological Process

• prolyl-tRNA aminoacylation (IEA) | GO:0006433
• translation (IEA) | GO:0006412
• tRNA aminoacylation for protein translation (IEA) | GO:0006418

Domains

• ( PF00587 ) tRNA synthetase class II core domain (G, H, P, S and T)
• ( PF03129 ) Anticodon binding domain
• ( PF04073 ) Aminoacyl-tRNA editing domain
• ( PF05727 ) Uncharacterised protein family (UPF0228)
• ( PF09180 ) Prolyl-tRNA synthetase, C-terminal
• ( TIGR00408 ) prolyl-tRNA synthetase
• ( TIGR00409 ) prolyl-tRNA synthetase
• ( TIGR00414 ) seryl-tRNA synthetase
• ( TIGR00418 ) threonyl-tRNA synthetase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_37784	0
	Description: None
WormBase	WBGene00004189	9.997093137033517e-262
	Description: locus:pars-1 status:Confirmed UniProt:Q22620 protein_id:CCD73349.1
Tetrahymena borealis	EI9_12209.1	9.997093137033517e-262
	Description: prolyl-tRNA synthetase (734 aa)
DictyBase	DDB_G0284197	9.997093137033517e-262
	Description: proS on chromosome: 4 position 1680128 to 1681774
Oxytricha	Contig15844.0.g111	9.997093137033517e-262
	Description: Anticodon binding domain
SGD	YHR020W	9.997093137033517e-262
	Description: YHR020W Protein of unknown function that may interact with ribosomes, based on co-purification experiments; has similarity to proline-tRNA ligase; YHR020W is an essential gene
Tetrahymena borealis	EI9_13502.1	9.997093137033517e-262
	Description: hypothetical protein (516 aa)

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00487020(coding)
ATGATAAAAATATTAAACAGATTCGTAAGGATTCAAAAATTTAATAATAATTATTTAAAA
AATATTAATAACAATTAAAATTTCTATAGCATTCATTAAAAATATCTTAATCACTTTTCA
AGGAAAATGGCTGAGAGCAAATTATACCTCACAAAGGACGAAACTTGCGATTACTTAAAA
AGCATTAATTTCGAATTTAAGAGATACGATCACGAACCTTGCTTTAATGTTGAAGATATG
CATAAATACTTAAAGCTCGAAAAGGCTCCTTTAATTAAGAATCTCTTCTATCAAGACAAG
AAGGGTAACTATTATTTAGTTGTAGCTAAGCATGATACTAAAGTTGAAAAAACTTTATGG
AAGTAAGTCAATCTTGCTCCTGGTAACATGCGTTTAGCTGCTGATGAAAAGCTTGAGGCT
GTTTTGAAGGTCAAGAGAGGACATGTTAATCCTTTCGCCTTAGTTAATGATACTGAAAAG
TTAGTTAAAGCTTTAATTATCGATGAACATTTGAAGAAAGAAGAATATTGGGCTTTCCAT
CCTATGGATAATTCTGCTTGCGTTGAATTCAAGCAAACTGAATTCTAAAAGTTTATCGAT
GCTATTGGCAGAACTTTTGTTCACGTGAGACTCGACTTATCTGAAGAAGAAGAGAAAAAG
CTCGCAGAATAAGCAAAGAAGGAAACTGCTAAAGTTGAAGAAGCTGGTCATACTAAATTA
GGTATTGATGTTAAAAAAGATCAAGATTTATCTGAATGGTACAAGCAAGTTATCACTAAA
TCTGAAATGATCGAATATTATGATATCTCTGGTTGCTACATTCTTCGTCCCCACGCTTAT
GCCATCTGGGAAATCATTTAGAGATTCTTTGATGACATCATCAAGGGATTCGATGTACAA
AATGCTTATTTCCCTATGTTTGTCACTGATAAGGCTTTAAACAAAGAAAAGGAACACGTT
GAAGGTTTCTCACCTGAAGTTGCTTGGGTTACTAGAAGTGGTTCCACTGATTTACCTGAA
CCTATTGCAGTTCGTCCTACATCAGAAACAATTATGTATCCTGCTTACTCCAAGTGGATC
AAGTCTCACAGAGATCTTCCCTTGAAATTAAACTAATGGACTAACGTAGTCCGTTGGGAA
TTCAAGGATCCTACTCCTTTCATTAGAACAAGAGAATTCTTATGGTAAGAAGGTCACACC
GCTCATGCCACTGATGCTGAAGCCACTGAATTTACTTTCCTTATCTAAGATTAATACAGA
AGAGTCTACGAAGAACTCCTTGCTGTTCCTGTTATCAAGGGTGTCAAGAGTGAAAATGAA
AAATTCCCTGGTGCTTACTTCTCTTCCACTATTGAAACTTGCATTCCTGCTAATGGTCGT
GCTGTCTAAGCTGCCACTTCTCACCACTTGGGATAAAACTTCTCAAAGATGTTTGATATT
TCCTTCTTAGATGGTGAAAAAAAGAAATAATACGCCTACCAAACTTCCTGGGGTCTTACT
ACTCGTACTATTGGTGTTATGATTCTTTATCACGGTGATGATAAGGGTCTTGTTTTACCT
CCTCTTGTTGCTAGCACTCAAGTTGTTATCGTTCCAATTATTAAAACCGGAGCTGATAAC
GAAAGAGTTTTAAACAAAGCTCATGAATTAAAGGCTGAATTAAAGAAGGCTGGTATCAGA
GTTTAGGTTGATGACAGAGATAACTATACTTCTGGTTGGAAATTCAACCATTGGGAAGTC
AAGGGTATTCCTTTAAGATTTGAAATTGGTCAAATGGATATGGATAAGAATTAAATTACA
GCAGTTTGGAGAGTCAACTCTCACAAGGAAGCTATTCCTAACGAAAGTATTATTGAAACT
ACTAAGTTAAGATTGAAAGAAATACAAGATTTAATGTTAACTAACTCCAAGAAAAAGTTT
AACGATAAGATTAAGCCTGCTAGTACCTGGGCTGAATTCATGACTTCTCTTAACTCTCGT
TGCATTGTCTATACTCCTTGGTGCAATGAAATTTCATGTGAAAAGGCTGTTAAGGAAAGA
TCAGCTCTTGAATCTAAGGGAACAGAAAATGAATCTGGTTTATCTGGATCTGCAAAGACT
TTGTGCATTCCTAATGAATAAGAACCTATCGCTGAAGGCACTAAGTGTTTCTCTTGCGGA
AAGCCTGCTCTTAAGAGAGTTTATTGGGGAAGATCTTATTGA

>TTHERM_00487020(gene)
ATGATAAAAATATTAAACAGATTCGTAAGGATTCAAAAATTTAATAATAATTATTTAAAA
AATATTAATAACAATTAAAATTTCTATAGCATTCATTAAAAATATCTTAATCACTTTTCA
AGGAAAATGGCTGAGAGCAAATTATACCTCACAAAGGACGAAACTTGCGATTACTTAAAA
AGCATTAATTTCGAATTTAAGAGATACGATCACGAACCTTGCTTTAATGTTGAAGATATG
CATAAATACTTAAAGCTCGAAAAGGCTCCTTTAATTAAGAATCTCTTCTATCAAGACAAG
AAGGGTAACTATTATTTAGTTGTAGCTAAGCATGATACTAAAGTTGAAAAAACTTTATGG
AAGTAAGTCAATCTTGCTCCTGGTAACATGCGTTTAGCTGCTGATGAAAAGCTTGAGGCT
GTTTTGAAGGTCAAGAGAGGACATGTTAATCCTTTCGCCTTAGTTAATGATACTGAAAAG
TTAGTAGGGATAAATTCTTTAATTTCAATTCAAAAGCTCAATTTTCCATTTTAAAGTTAA
AAATTTGAATTATTATGATCAAAAAAAGATGAATGAGAATAAGCATATTATTTGCACCCA
TAAATTATCAAACACCTAATAAAAATATCAAACTTATACAATAAGTTTTTTAAAATGAGC
GAAAATAGTGTTAATAAAATCACATTGTGAATACGTAATTTAGCATAAGACTTATGAAAA
TGTATTTTTAATAAAAAGGTTAAAGCTTTAATTATCGATGAACATTTGAAGAAAGAAGAA
TATTGGGCTTTCCATCCTATGGATAATTCTGCTTGCGTTGAATTCAAGCAAACTGAATTC
TAAAAGTTTATCGATGCTATTGGCAGAACTTTTGTTCACGTGAGACTCGACTTATCTGAA
GAAGAAGAGAAAAAGCTCGCAGAATAAGCAAAGAAGGAAACTGCTAAAGTTGAAGAAGCT
GGTCATACTAAATTAGGTATTGATGTTAAAAAAGATCAAGATTTATCTGAATGGTACAAG
CAAGTTATCACTAAATCTGAAATGATCGAATATTATGATATCTCTGGTTGCTACATTCTT
CGTCCCCACGCTTATGCCATCTGGGAAATCATTTAGGTAATACATTTTACAATATTTTTA
CTACATTTAAAAAAGCTAGATCAGAAAAAAATAAAAAAGATTATTTATATATTTCTAAAC
GTTCTTCATAAAAAAATTAAATTATTGCGAAGTTAGTTAATAGTATATCTAAAATATATC
AAAAATAAATAGATATTAGTTAGTTAGTAAGCGAAAAAATAAATCTTTTTAAAAGAACGC
GAAAAAAATTGATAGAAAATTTAGATTTAATTTGTCTAATCTGAAAATTTTGAACTTTTT
TTATTTTTTTGTTAAATTTAAATTTCAATTAAAAATAATAATAATAGAGATTCTTTGATG
ACATCATCAAGGGATTCGATGTACAAAATGCTTATTTCCCTATGTTTGTCACTGATAAGG
CTTTAAACAAAGAAAAGGAACACGTTGAAGGTTTCTCACCTGAAGTTGCTTGGGTTACTA
GAAGTGGTTCCACTGATTTACCTGAACCTATTGCAGTTCGTCCTACATCAGAAACAATTA
TGTATCCTGCTTACTCCAAGTGGATCAAGTCTCACAGAGATCTTCCCTTGAAATTAAACT
AATGGACTAACGTAGTCCGTTGGGAATTCAAGGATCCTACTCCTTTCATTAGAACAAGGT
ATTTATTATAAATTAAAATGCTTTTAAATAACTATTAAATATTCTAAAATCTATAGAAAG
TTTTAATTTTTAAATTCAATATTTTATTAAAAATTAATATAAATTTATTTATTTCTTAGA
GAATTCTTATGGTAAGAAGGTCACACCGCTCATGCCACTGATGCTGAAGCCACTGAATTT
ACTTTCCTTATCTAAGATTAATACAGAAGAGTCTACGAAGAACTCCTTGCTGTTCCTGTT
ATCAAGGGTGTCAAGAGTGAAAATGAAAAATTCCCTGGTGCTTACTTCTCTTCCACTATT
GAAACTTGCATTCCTGCTAATGGTCGTGCTGTCTAAGCTGCCACTTCTCACCACTTGGGA
TAAAACTTCTCAAAGATGTTTGATATTTCCTTCTTAGATGGTGAAAAAAAGAAATAATAC
GCCTACCAAACTTCCTGGGGTCTTACTACTCGTACTATTGGTGTTATGATTCTTTATCAC
GGTGATGATAAGGTAATTTTTATTTTAAAGTTAATAAATTTACATTTAATATTTATGCAA
TTTGTAATTAGGGTCTTGTTTTACCTCCTCTTGTTGCTAGCACTCAAGTTGTTATCGTTC
CAATTATTAAAACCGGAGCTGATAACGAAAGAGTTTTAAACAAAGCTCATGAATTAAAGG
CTGAATTAAAGAAGGCTGGTATCAGAGTTTAGGTTGATGACAGAGATAACTATACTTCTG
GTTGGAAATTCAACCATTGGGAAGTCAAGGGTATTCCTTTAAGATTTGAAATTGGTCAAA
TGGATATGGATAAGAATTAAATTACAGCAGTTTGGAGAGTCAACTCTCACAAGGAAGCTA
TTCCTAACGAAAGTATTATTGAAACTACTAAGTTAAGATTGAAAGAAATACAAGATTTAA
TGTTAACTAACTCCAAGAAAAAGTTTAACGATAAGATTAAGCCTGCTAGTACCTGGGCTG
AATTCATGACTTCTCTTAACTCTCGTTGCATTGTCTATACTCCTTGGTAATTATTAAAGA
CAATAAATACAGTTTTCATTTCATATCGATTTATGAAAACTGATAATTAAATTTGAATAT
TTATTGAATTTTTCTTTTTTAATAAAAGGTGCAATGAAATTTCATGTGAAAAGGCTGTTA
AGGAAAGATCAGCTCTTGAATCTAAGGGAACAGAAAATGTAAATAAATAAATATAAAATC
AAAATCATAGAAAATATTAAAATATTTTTAAATAATAGGAATCTGGTTTATCTGGATCTG
CAAAGACTTTGTGCATTCCTAATGAATAAGAACCTATCGCTGAAGGCACTAAGTGTTTCT
CTTGCGGAAAGCCTGCTCTTAAGAGAGTTTATTGGGGAAGATCTTATTGA

>TTHERM_00487020(protein)
MIKILNRFVRIQKFNNNYLKNINNNQNFYSIHQKYLNHFSRKMAESKLYLTKDETCDYLK
SINFEFKRYDHEPCFNVEDMHKYLKLEKAPLIKNLFYQDKKGNYYLVVAKHDTKVEKTLW
KQVNLAPGNMRLAADEKLEAVLKVKRGHVNPFALVNDTEKLVKALIIDEHLKKEEYWAFH
PMDNSACVEFKQTEFQKFIDAIGRTFVHVRLDLSEEEEKKLAEQAKKETAKVEEAGHTKL
GIDVKKDQDLSEWYKQVITKSEMIEYYDISGCYILRPHAYAIWEIIQRFFDDIIKGFDVQ
NAYFPMFVTDKALNKEKEHVEGFSPEVAWVTRSGSTDLPEPIAVRPTSETIMYPAYSKWI
KSHRDLPLKLNQWTNVVRWEFKDPTPFIRTREFLWQEGHTAHATDAEATEFTFLIQDQYR
RVYEELLAVPVIKGVKSENEKFPGAYFSSTIETCIPANGRAVQAATSHHLGQNFSKMFDI
SFLDGEKKKQYAYQTSWGLTTRTIGVMILYHGDDKGLVLPPLVASTQVVIVPIIKTGADN
ERVLNKAHELKAELKKAGIRVQVDDRDNYTSGWKFNHWEVKGIPLRFEIGQMDMDKNQIT
AVWRVNSHKEAIPNESIIETTKLRLKEIQDLMLTNSKKKFNDKIKPASTWAEFMTSLNSR
CIVYTPWCNEISCEKAVKERSALESKGTENESGLSGSAKTLCIPNEQEPIAEGTKCFSCG
KPALKRVYWGRSY