Identifiers and Description

Gene Model Identifier

TTHERM_00492850

Standard Name

ILS1 (IsoLeucine-tRNA Synthetase 1 )

Aliases

cupC | PreTt04221 | 61.m00208 | 3711.m00056 | ILSA

Description

ILS1 ilsA isoleucyl-tRNA synthetase protein; Isoleucyl-tRNA synthetase; contains two C-terminal leucine zipper motifs and sequence similarity with the S. cerevisiae ileRS protein; transcript induced during meitoic prophase and nutritional shift-up but decreased by starvation; Isoleucine-tRNA ligase, type 2

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Cellular Component

Biological Process

Domains

  • ( PF00133 ) tRNA synthetases class I (I, L, M and V)
  • ( PF08264 ) Anticodon-binding domain of tRNA ligase
  • ( PF19302 ) Domain of unknown function (DUF5915)

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:1371507: Csank C, Martindale DW (1992) Isoleucyl-tRNA synthetase from the ciliated protozoan Tetrahymena thermophila. DNA sequence, gene regulation, and leucine zipper motifs. The Journal of biological chemistry 267(7):4592-9
  2. Ref:2663194: Martindale DW, Gu ZM, Csank C (1989) Isolation and complete sequence of the yeast isoleucyl-tRNA synthetase gene (ILS1). Current genetics 15(2):99-106
  3. Ref:3005971: Martindale DW, Martindale HM, Bruns PJ (1986) Tetrahymena conjugation-induced genes: structure and organization in macro- and micronuclei. Nucleic acids research 14(3):1341-54
  4. Ref:6646127: Martindale DW, Bruns PJ (1983) Cloning of abundant mRNA species present during conjugation of Tetrahymena thermophila: identification of mRNA species present exclusively during meiosis. Molecular and cellular biology 3(10):1857-65

Sequences 

>TTHERM_00492850(coding)
ATGATTCTTTTCAAAAAATTATTAATATAAAAAAAAGTAAATTATCTAAGCAGATTATTA
ATGGCTTCAAAGACCACCTTCAAAGATCTTTAGGAAATTCCTGATTTCCCTAAGGAAGAA
GAGAACATCCTCAAGTTTTGGGATGAAATTAATGCTTTTAAGCAACAATTAGAAAAAACT
AAGGATTGCCCTCCTTTCACTTTCTACGATGGCCCACCATTCGCTACCGGTTTACCTCAC
TATGGTAACCTTCTTGCTGGTACAATCAAGGATGTCGTTTGCAGATACGCTTCTCAAAAT
GGCAAATATGTTGAAAGAAGATTCGGTTGGGATTGTCACGGTCTTCCAGTTGAATATGAA
ATCGATAAGAAGCTCGGTATCACCAATAGACAAGAAGTCTTAAAGATGGGTGTCGACAAG
TACAATGCTGAATGCCGTAGCATCGTCATGAGATACGCTTAAGAATGGAGATCAATCGTG
AACAGATTTGGTCGTTGGGTTGACTTTGACAATGATTACAAAACTCTTGATTTGAAGTTT
ATGGAATCCGTTTGGTGGGTTTTCAAGCAAATGTTCGATAAGGGATTAGTTTATAGAGGT
TGCAAGGTTATGCCCTACTCCAATGGTTGTGCAACTGTCTTATCTAACTTCGAAACTCAA
CAAAACTACAAGGAAGTTGATGATCCTTCTCTCTTCATCGCTTTTAAGACTGCCGAAGAT
CCTAAGACCAAGTTCATTGCTTGGACAACCACTCCTTGGACACTTCCTTCTAACTTGGCT
TTGGTTATCAACAAGGACTTCGATTACGTTAAGGTTTTAGATGCTAAGACCTAAGAACAC
TACATTCTTGCAGAATGCCGTCTCCCTGAATTATACAAAAAGGATAAGGATGGATACAAG
ATCTTAGAAAAATTCAAAGGTTCTGAACTCGTAGGCAGAGAATATGAACCTCTTTTCCCC
TATTTCCTCTCTAGAAAGCAAGATGGCTGCTTCAGAATTCTCGCTGGTGACTTCGTTACT
GCTGATGCTGGTACTGGTATCGTCCACTGCGCCCCTGGTTTTGGTGATGACGATTACAAA
GTCTCAGTTGCAAATAACATCATCAAGCCCGATGATCCACCCGTACCTGTTGATGAAAAC
GGTCATTTCACTAATGTCGTTTCTGATTTTGCTGGTGTTTACATCAAGGAAGCTGATAAG
TTAATTAGAAAGAACTTGAAGGAAAGAGGTTTGTTGCTCGTTGATTCTTCATTCAAGCAC
AACTATCCCTTCTGCTGGAGATCTGATACCCCCTTGATTTACAAGGCTGTTCACTGCTGG
TTCATTAAGGTTACTGCCCTTAAGGATGACCTTTTAGCTAACAACAAGAAGGCTTATTGG
GTTCCTAAATTTGCTTAAGAAGGACGTTTCAACAACTGGTTGTAGAATGTCTCTGATTGG
TGTTTCTCTAGATCTAGATTCTGGGGTAACCCTATCCCTATTTGGGTTTCTGAAGATTTT
GAAGAAGTTGTTTGCATTGGATCAGTTGAAGAACTCAAGAAATTAACTGGTGCAACTGAA
ATCACTGATTTACACAAAGATTTTATTGATCACCTTACCATCCCATCCTAAAAGGGTAAG
GGGGTCTTAAGACGTATTGATGAAGTCTTTGATTGCTGGTTCGAATCTGGTTCTATGCCT
TATGGTCAATAACACTATCCCTTCTCTATGAACGAAGAAGAGTTCTCTAAGAGATTCCCT
GCTGATTTCATCGGTGAAGGTATTGATCAAACTAGAGGTTGGTTCTATACTCTTAACGTT
ATTTCTACTGCCTTAAGAAATTCCAACCCCTACAAAAACCTTATTGTTAACGGTATCGTT
CTTGCTGCTGACGGAAAGAAGATGTCTAAGTCAAAGAAGAACTACGATGATCCCTTGCTC
ATTGCCTCCAAGTACTCCGTTGATGCTATCCGTTTATATATGATCAACTCTCCTTTAGTC
AGAGCTGAAGAAATGAGTTTCAAGTCCGAAGGTGTTTTTGCTGTTAAGAAAGATATCTTC
TTACCCTGGTACAATGCTTACAAATTCTTAATCTAAAGTATCACTAGATGGGAACTCGCT
ACTGGAAAAGACTACATGTTCAACGAACAACTCTCTGTTGATACTACTAAATTAACTAAT
CCTACTGATAGATGGATTATTATCTCCTGCCAAAACTTGATCAACTATGTCAGAATTGAA
ATGGAAAAGTATCACTTGTACAATGTCGTTCCTCGTTTAATCCACTTCTTAGAAAACTTA
ACCAACTGGTATATTAGATTAAACAGAAACAGACTAAAAGGTGATTACGGTCTTGAAGAA
TAAGAAACTTCCCTCAACGTCTTATTCAACGTTATCTTAAACTCCACTATTTTAATGTCA
CCTTTAGTTCCTTTCATCACTGAAAGTTTCTATCAAAACTTAAGAAAGGTCATTCCTAAG
GGTTCTTCTTACTTAGAAGAATCTATCCACTTCTTGAGAATCCCTACTCCTAAGCAAGAA
CTTCTCGATGAAAAGATCGAAAGAAACTTTGAAAGAATGTAAAACATCATCAACTTTGCT
CGTACTTTAAGAGAAAAGAGAAAGGTCTCTCTTAAGCAACCTATCATGTCTTTGACTGTC
ATCAATTAAGACTAAGAATTCCACGATTCCTTAAAGGATTACATTCAATATATTGAAGAT
GAAATCAACACTCCTTCTATCCTCCACGAAATTAACACTGCTAATTATGTTGACTTAAAG
GCCATTCCTAATCACAAACTCCTTGGACAAAAACTTGGTAAGGAATACAATAAGGATCTT
AAGGCTGCTGCCGGTAACTTGTCTGCCAAGGATATTGAAACCTTGAAGACTACTGGATCT
ATTGATTTAGTTGGCAAGAAATTACTTTTGGAAGACTTCACCATTACTCAAAATTACAAG
AAAGAATACTCTAGTGGTGACTTAGAACTTGGTGGTGAAGGTGAAGTTATTTTACTTTTG
AACCTCGCTCAAGATGAAAAGTTAAAGAGCAAAGGTCTTGTTAGAGAATTTACCAGCAAC
GTTTAAAAGACCAAGAAGAAAACCGGCTTAAAGGTTGACGATAACATCGTTATTTATTAT
GATGTTACCAAAGCACCCAAGTTAAATGCTGCTATTTAATCCGATTTAGAAGCTGTCCAA
AAGGTCTTAAAGAAACCCCTCGTTCCTTTATCTGAAAAGAATGCTGCTCTTAAGATTGTT
GAAAACTCTTTACTTACTTTCTAGGTTGATGAAGAATCCGTTACTATCGAAATCGCTTAT
GCTTGA



>TTHERM_00492850(gene)
ATTTGAAAAGATAGCCCAGAAAAGGAGAAACTAACAATATCTTATAATTAAATTTATGAT
TCTTTTCAAAAAATTATTAATATAAAAAAAAGTAAATTATCTAAGCAGATTATTAATGGC
TTCAAAGACCACCTTCAAAGATCTTTAGGAAATTCCTGATTTCCCTAAGGAAGAAGAGAA
CATCCTCAAGTTTTGGGATGAAATTAATGCTTTTAAGCAACAATTAGAAAAAACTAAGGA
TTGCCCTCCTTTCACTTTCTACGATGGCCCACCATTCGCTACCGGTTTACCTCACTATGG
TAACCTTCTTGCTGGTACAATCAAGGATGTCGTTTGCAGATACGCTTCTCAAAATGGCAA
ATATGTTGAAAGAAGATTCGGTTGGGATTGTCACGGTCTTCCAGTTGAATATGAAATCGA
TAAGAAGCTCGGTATCACCAATAGACAAGAAGTCTTAAAGATGGGTGTCGACAAGTACAA
TGCTGAATGCCGTAGCATCGTCATGAGATACGCTTAAGAATGGAGATCAATCGTGAACAG
ATTTGGTCGTTGGGTTGACTTTGACAATGATTACAAAACTCTTGATTTGAAGTTTATGGA
ATCCGTTTGGTGGGTTTTCAAGCAAATGTTCGATAAGGGATTAGTTTATAGAGGTTGCAA
GGTTATGCCCTACTCCAATGGTTGTGCAACTGTCTTATCTAACTTCGAAACTCAACAAAA
CTACAAGGAAGTTGATGATCCTTCTCTCTTCATCGCTTTTAAGACTGCCGAAGATCCTAA
GACCAAGTTCATTGCTTGGACAACCACTCCTTGGACACTTCCTTCTAACTTGGCTTTGGT
TATCAACAAGGACTTCGATTACGTTAAGGTTTTAGATGCTAAGACCTAAGAACACTACAT
TCTTGCAGAATGCCGTCTCCCTGAATTATACAAAAAGGATAAGGATGGATACAAGATCTT
AGAAAAATTCAAAGGTTCTGAACTCGTAGGCAGAGAATATGAACCTCTTTTCCCCTATTT
CCTCTCTAGAAAGCAAGATGGCTGCTTCAGAATTCTCGCTGGTGACTTCGTTACTGCTGA
TGCTGGTACTGGTATCGTCCACTGCGCCCCTGGTTTTGGTGATGACGATTACAAAGTCTC
AGTTGCAAATAACATCATCAAGCCCGATGATCCACCCGTACCTGTTGATGAAAACGGTCA
TTTCACTAATGTCGTTTCTGATTTTGCTGGTGTTTACATCAAGGAAGCTGATAAGTTAAT
TAGAAAGAACTTGAAGGAAAGAGGTTTGTTGCTCGTTGATTCTTCATTCAAGCACAACTA
TCCCTTCTGCTGGAGATCTGATACCCCCTTGATTTACAAGGCTGTTCACTGCTGGTTCAT
TAAGGTTACTGCCCTTAAGGATGACCTTTTAGCTAACAACAAGAAGGCTTATTGGGTTCC
TAAATTTGCTTAAGAAGGACGTTTCAACAACTGGTTGTAGAATGTCTCTGATTGGTGTTT
CTCTAGATCTAGATTCTGGGGTAACCCTATCCCTATTTGGGTTTCTGAAGATTTTGAAGA
AGTTGTTTGCATTGGATCAGTTGAAGAACTCAAGAAATTAACTGGTGCAACTGAAATCAC
TGATTTACACAAAGATTTTATTGATCACCTTACCATCCCATCCTAAAAGGGTAAGGGGGT
CTTAAGACGTATTGATGAAGTCTTTGATTGCTGGTTCGAATCTGGTTCTATGCCTTATGG
TCAATAACACTATCCCTTCTCTATGAACGAAGAAGAGTTCTCTAAGAGATTCCCTGCTGA
TTTCATCGGTGAAGGTATTGATCAAACTAGAGGTTGGTTCTATACTCTTAACGTTATTTC
TACTGCCTTAAGAAATTCCAACCCCTACAAAAACCTTATTGTTAACGGTATCGTTCTTGC
TGCTGACGGAAAGAAGATGTCTAAGTCAAAGAAGAACTACGATGATCCCTTGCTCATTGC
CTCCAAGTACTCCGTTGATGCTATCCGTTTATATATGATCAACTCTCCTTTAGTCAGAGC
TGAAGAAATGAGTTTCAAGTCCGAAGGTGTTTTTGCTGTTAAGAAAGATATCTTCTTACC
CTGGTACAATGCTTACAAATTCTTAATCTAAAGTATCACTAGATGGGAACTCGCTACTGG
AAAAGACTACATGTTCAACGAACAACTCTCTGTTGATACTACTAAATTAACTAATCCTAC
TGATAGATGGATTATTATCTCCTGCCAAAACTTGATCAACTATGTCAGAATTGAAATGGA
AAAGTATCACTTGTACAATGTCGTTCCTCGTTTAATCCACTTCTTAGAAAACTTAACCAA
CTGGTATATTAGATTAAACAGAAACAGACTAAAAGGTGATTACGGTCTTGAAGAATAAGA
AACTTCCCTCAACGTCTTATTCAACGTTATCTTAAACTCCACTATTTTAATGTCACCTTT
AGTTCCTTTCATCACTGAAAGTTTCTATCAAAACTTAAGAAAGGTCATTCCTAAGGGTTC
TTCTTACTTAGAAGAATCTATCCACTTCTTGAGAATCCCTACTCCTAAGCAAGAACTTCT
CGATGAAAAGATCGAAAGAAACTTTGAAAGAATGTAAAACATCATCAACTTTGCTCGTAC
TTTAAGAGAAAAGAGAAAGGTCTCTCTTAAGCAACCTATCATGTCTTTGACTGTCATCAA
TTAAGACTAAGAATTCCACGATTCCTTAAAGGATTACATTCAATATATTGAAGATGAAAT
CAACACTCCTTCTATCCTCCACGAAATTAACACTGCTAATTATGTTGACTTAAAGGCCAT
TCCTAATCACAAACTCCTTGGACAAAAACTTGGTAAGGAATACAATAAGGATCTTAAGGC
TGCTGCCGGTAACTTGTCTGCCAAGGATATTGAAACCTTGAAGACTACTGGATCTATTGA
TTTAGTTGGCAAGAAATTACTTTTGGAAGACTTCACCATTACTCAAAATTACAAGAAAGA
ATACTCTAGTGGTGACTTAGAACTTGGTGGTGAAGGTGAAGTTATTTTACTTTTGAACCT
CGCTCAAGATGAAAAGTTAAAGAGCAAAGGTCTTGTTAGAGAATTTACCAGCAACGTTTA
AAAGACCAAGAAGAAAACCGGCTTAAAGGTTGACGATAACATCGTTATTTATTATGATGT
TACCAAAGCACCCAAGTTAAATGCTGCTATTTAATCCGATTTAGAAGCTGTCCAAAAGGT
CTTAAAGAAACCCCTCGTTCCTTTATCTGAAAAGAATGCTGCTCTTAAGATTGTTGAAAA
CTCTTTACTTACTTTCTAGGTTGATGAAGAATCCGTTACTATCGAAATCGCTTATGCTTG
AAAGATATTCTATTTAATAAACAATACTATGATTTTTTTTTTATTTAATATGATTACTAA
ACATTTAATTTATAATTAAAAACTATCTTTCTTTCTACCTATTTTTCTGTCTGTTTGTTA
GTCTACATTTCTATTTTGTAGATTTACTTCAATTTTTTAAATTTTAAATAAAT



>TTHERM_00492850(protein)
MILFKKLLIQKKVNYLSRLLMASKTTFKDLQEIPDFPKEEENILKFWDEINAFKQQLEKT
KDCPPFTFYDGPPFATGLPHYGNLLAGTIKDVVCRYASQNGKYVERRFGWDCHGLPVEYE
IDKKLGITNRQEVLKMGVDKYNAECRSIVMRYAQEWRSIVNRFGRWVDFDNDYKTLDLKF
MESVWWVFKQMFDKGLVYRGCKVMPYSNGCATVLSNFETQQNYKEVDDPSLFIAFKTAED
PKTKFIAWTTTPWTLPSNLALVINKDFDYVKVLDAKTQEHYILAECRLPELYKKDKDGYK
ILEKFKGSELVGREYEPLFPYFLSRKQDGCFRILAGDFVTADAGTGIVHCAPGFGDDDYK
VSVANNIIKPDDPPVPVDENGHFTNVVSDFAGVYIKEADKLIRKNLKERGLLLVDSSFKH
NYPFCWRSDTPLIYKAVHCWFIKVTALKDDLLANNKKAYWVPKFAQEGRFNNWLQNVSDW
CFSRSRFWGNPIPIWVSEDFEEVVCIGSVEELKKLTGATEITDLHKDFIDHLTIPSQKGK
GVLRRIDEVFDCWFESGSMPYGQQHYPFSMNEEEFSKRFPADFIGEGIDQTRGWFYTLNV
ISTALRNSNPYKNLIVNGIVLAADGKKMSKSKKNYDDPLLIASKYSVDAIRLYMINSPLV
RAEEMSFKSEGVFAVKKDIFLPWYNAYKFLIQSITRWELATGKDYMFNEQLSVDTTKLTN
PTDRWIIISCQNLINYVRIEMEKYHLYNVVPRLIHFLENLTNWYIRLNRNRLKGDYGLEE
QETSLNVLFNVILNSTILMSPLVPFITESFYQNLRKVIPKGSSYLEESIHFLRIPTPKQE
LLDEKIERNFERMQNIINFARTLREKRKVSLKQPIMSLTVINQDQEFHDSLKDYIQYIED
EINTPSILHEINTANYVDLKAIPNHKLLGQKLGKEYNKDLKAAAGNLSAKDIETLKTTGS
IDLVGKKLLLEDFTITQNYKKEYSSGDLELGGEGEVILLLNLAQDEKLKSKGLVREFTSN
VQKTKKKTGLKVDDNIVIYYDVTKAPKLNAAIQSDLEAVQKVLKKPLVPLSEKNAALKIV
ENSLLTFQVDEESVTIEIAYA