Identifiers and Description

Gene Model Identifier

TTHERM_00497960

Standard Name

CCT7 (Chaperonin Containing TCP-1 ortholog 7 )

Aliases

TtCCTeta | PreTt06961 | 62.m00245 | 3715.m00106

Description

CCT7 TCP-1 (CTT or eukaryotic type II) chaperonin family eta subunit; CCT-eta chaperonin subunit; expressed during cilia biogenesis and conjugation; Chaperone tailless complex polypeptide 1 (TCP-1)

Genome Browser (Macronucleus)



Genome Browser (Micronucleus)

External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

Domains

  • ( PF00118 ) TCP-1/cpn60 chaperonin family

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:14567989: Seixas C, Casalou C, Melo LV, Nolasco S, Brogueira P, Soares H (2003) Subunits of the chaperonin CCT are associated with Tetrahymena microtubule structures and are involved in cilia biogenesis. Experimental cell research 290(2):303-21
  2. Ref:11718895: Casalou C, Cyrne L, Rosa MR, Soares H (2001) Microtubule cytoskeleton perturbation induced by taxol and colchicine affects chaperonin containing TCP-1 (CCT) subunit gene expression in Tetrahymena cells. Biochimica et biophysica acta 1522(1):9-21
  3. Ref:10524223: Domingues C, Soares H, Rodrigues-Pousada C, Cyrne L (1999) Structure of Tetrahymena CCT theta gene and its expression under colchicine treatment. Biochimica et biophysica acta 1446(3):443-9
  4. Ref:9819444: Won KA, Schumacher RJ, Farr GW, Horwich AL, Reed SI (1998) Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT. Molecular and cellular biology 18(12):7584-9
  5. Ref:9337846: Soares H, Cyrne L, Casalou C, Ehmann B, Rodrigues-Pousada C (1997) The third member of the Tetrahymena CCT subunit gene family, TpCCT alpha, encodes a component of the hetero-oligomeric chaperonin complex. The Biochemical journal 326 ( Pt 1)( ):21-9
  6. Ref:8925913: Cyrne L, Guerreiro P, Cardoso AC, Rodrigues-Pousada C, Soares H (1996) The Tetrahymena chaperonin subunit CCT eta gene is coexpressed with CCT gamma gene during cilia biogenesis and cell sexual reproduction. FEBS letters 383(3):277-83
  7. Ref:8573069: Walkley NA, Demaine AG, Malik AN (1996) Cloning, structure and mRNA expression of human Cctg, which encodes the chaperonin subunit CCT gamma. The Biochemical journal 313 ( Pt 2)( ):381-9
  8. Ref:7961900: Soares H, Penque D, Mouta C, Rodrigues-Pousada C (1994) A Tetrahymena orthologue of the mouse chaperonin subunit CCT gamma and its coexpression with tubulin during cilia recovery. The Journal of biological chemistry 269(46):29299-307

Sequences

>TTHERM_00497960(coding)
ATGAGTTATCTTTTGCAACCTACCATTTTGCTCTTGAAGGACGGTACTGATACTTCCTAA
GGAAAGGCTTAAATTGTTTCCAACATTAATGCTGTCTAATCTATTGTAGAAATCGTTAAG
ACCACTTTAGGTCCCCGTGGTATGGATAAATTGATTGAAGGTGGAATGAAGGGAGCCACT
ATTTCCAATGATGGTGCTACTATTTTAAACTTATTAGATATTGTTCACCCTGCTGCTAAG
ACTCTTGTTGATATTGCTAAGGCTTAAGACGATGAAGTTGGTGATGGTACCACTTCTGTC
TGCCTTTTGGCTGGTGAATTATTGAAGGAATCTAAGTACTTCATCGAAGAAGGTATGCAC
CCATAAATTATCACTAAGGGTTACAAGGAAGCCCTCAAGTTAGCTCTTTAATTCTTACAC
GAAAATGCTCACTCTGTAGCTGATAAGAACGAAACTGAAAAGAGAGAAATGCTCATTAAG
TGCGCTTAAACCTCTTTAAACTCCAAATTATTAGCTCATTACAAGGAATTCTTCTCTGAG
TTAGTTGTTTAAGCCGTTGAAACTCTTGAAACTAATCTCCTCGACAAAGACCTTATCGGT
ATCAAGATGGTCACCGGTGGTTCAGTCACTGATTCTTTCTTGGTTAGTGGTGTCGCTTTC
AAGAAAACCTTCTCTTATGCAGGTTTTGAACAACAACCCAAAAAGTTCAATAACCCTAAG
ATTTGCTTACTTAACATCGAATTAGAATTAAAGGCTGAAAAGGAAAATGCTGAAATTAGA
ATTGAAAATCCTGATGATTACAAGTCAATTGTTGATGCTGAATGGGAGTTGATTTATGAA
AAGTTAAGAAAGATTGTTGAATCTGGTGCTAACATTGTTCTCTCCAAGCTTCCTATTGGT
GATTTGGCCACTCAATACTTCGCTGATCGTAACATTTTCTGTGCTGGTCGTGTTGATGCT
GAAGATATGAAGAGAGTCCAAAAATCTACTGGTGCCATCGTTCAAACCACTGTCAATGGT
TTGACTGAAGATGTCTTAGGTACTTGCAACCAATTCGAAGAAGTTTAAATCGGTGCTGAA
AGATATAACCTCTTCAAGGATTGCCCTCACTCTAAGAGTGCTACCATCATTTTAAGAGGT
GGTGCTGAATAATTCATTGCTGAAGCTGAACGTTCTCTTAATGATGCAATCATGATCGTC
AGAAGATGCATGAAGGCCAATAAAATCGTTCCTGGTGGTGGTGCCATCGAATTAGAAATC
TCTCGTCTTCTCCGTTTACACTCCAGAAAGACTGAAGGAAAGATCTAATTAGTTATTAAT
GCTTTTGCTAAGGCTCTTGAAGTCATTCCCAGAACTATTGCTGATAATGCTGGTCACGAC
TCCATTCAAGTTCTTAATAAACTCCGTCAAAAGCATGCTATTGAAACCGAACAATCTAGA
AACTTCGGTGTTGATATTAATGCTGCTGATGGTATTGGCAATAACTACGAAAATTTTGTT
TGGGAACCTATCGTTGTCAGAAAAAATGCTTTGTCTGCTGCCACTGAAGCTGCTTGCACT
ATTTTAAGTATTGATGAAACTGTTAGAAATCCCAAGAGTGAACAACCTAAGGCTCCCCCT
GGTGGACTCAGAAGAGGTGGTCCTCAAGGAATGGCTGGTTTGGCTAAAAATGCTAAGCTC
GGAAAGTGA


>TTHERM_00497960(gene)
TTCATTGATAATTACATAAAAACAGATTTGTATCCAAAAAATTAAATAAATTAATTAAAA
TAAATAAATAAACTAAAAAGGCAAAAAGTTAAAAAGTATATTTAATATAAAATATACATA
AAAAAAATCTTTAAAAAAATCAAAAACAAAAAGCACTCAAAATTATACAACCACATAATA
AAGCTATGAGTTATCTTTTGCAACCTACCATTTTGCTCTTGAAGGACGGTACTGATACTT
CCTAAGGAAAGGCTTAAATTGTTTCCAACATTAATGCTGTCTAATCTATTGTAGAAATCG
TTAAGACCACTTTAGGTCCCCGTGGTATGGATAAATTGATTGAAGGTGGAATGAAGGGAG
CCACTATTTCCAATGATGGTGCTACTATTTTAAACTTATTAGATATTGTTCACCCTGCTG
CTAAGACTCTTGTTGATATTGCTAAGGCTTAAGACGATGAAGTTGGTGATGGTACCACTT
CTGTCTGCCTTTTGGCTGGTGAATTATTGAAGGAATCTAAGTACTTCATCGAAGAAGGTA
TGCACCCATAAATTATCACTAAGGGTTACAAGGAAGCCCTCAAGTTAGCTCTTTAATTCT
TACACGAAAATGCTCACTCTGTAGCTGATAAGAACGAAACTGAAAAGAGAGAAATGCTCA
TTAAGTGCGCTTAAACCTCTTTAAACTCCAAATTATTAGCTCATTACAAGGAATTCTTCT
CTGAGTTAGTTGTTTAAGCCGTTGAAACTCTTGAAACTAATCTCCTCGACAAAGACCTTA
TCGGTATCAAGATGGTCACCGGTGGTTCAGTCACTGATTCTTTCTTGGTTAGTGGTGTCG
CTTTCAAGAAAACCTTCTCTTATGCAGGTTTTGAACAACAACCCAAAAAGTTCAATAACC
CTAAGATTTGCTTACTTAACATCGAATTAGAATTAAAGGCTGAAAAGGAAAATGCTGAAA
TTAGAATTGAAAATCCTGATGATTACAAGTCAATTGTTGATGCTGAATGGGAGTTGATTT
ATGAAAAGTTAAGAAAGATTGTTGAATCTGGTGCTAACATTGTTCTCTCCAAGCTTCCTA
TTGGTGATTTGGCCACTCAATACTTCGCTGATCGTAACATTTTCTGTGCTGGTCGTGTTG
ATGCTGAAGATATGAAGAGAGTCCAAAAATCTACTGGTGCCATCGTTCAAACCACTGTCA
ATGGTTTGACTGAAGATGTCTTAGGTACTTGCAACCAATTCGAAGAAGTTTAAATCGGTG
CTGAAAGATATAACCTCTTCAAGGATTGCCCTCACTCTAAGAGTGCTACCATCATTTTAA
GAGGTGGTGCTGAATAATTCATTGCTGAAGCTGAACGTTCTCTTAATGATGCAATCATGA
TCGTCAGAAGATGCATGAAGGCCAATAAAATCGTTCCTGGTGGTGGTGCCATCGAATTAG
AAATCTCTCGTCTTCTCCGTTTACACTCCAGAAAGACTGAAGGAAAGATCTAATTAGTTA
TTAATGCTTTTGCTAAGGCTCTTGAAGTCATTCCCAGAACTATTGCTGATAATGCTGGTC
ACGACTCCATTCAAGTTCTTAATAAACTCCGTCAAAAGCATGCTATTGAAACCGAACAAT
CTAGAAACTTCGGTGTTGATATTAATGCTGCTGATGGTATTGGCAATAACTACGAAAATT
TTGTTTGGGAACCTATCGTTGTCAGAAAAAATGCTTTGTCTGCTGCCACTGAAGCTGCTT
GCACTATTTTAAGTATTGATGAAACTGTTAGAAATCCCAAGAGTGAACAACCTAAGGCTC
CCCCTGGTGGACTCAGAAGAGGTGGTCCTCAAGGAATGGCTGGTTTGGCTAAAAATGCTA
AGCTCGGAAAGTGAGTTTTAAATAATTAAGCAAAGAAACAATAAAATTAAATCAATATTA
TTCTTAATTATCATTTATAATGTAATTATAGGTCATTTTTTGTATATTTATTTTTATTAA
GTGTTTTAAATAAATTAG


>TTHERM_00497960(protein)
MSYLLQPTILLLKDGTDTSQGKAQIVSNINAVQSIVEIVKTTLGPRGMDKLIEGGMKGAT
ISNDGATILNLLDIVHPAAKTLVDIAKAQDDEVGDGTTSVCLLAGELLKESKYFIEEGMH
PQIITKGYKEALKLALQFLHENAHSVADKNETEKREMLIKCAQTSLNSKLLAHYKEFFSE
LVVQAVETLETNLLDKDLIGIKMVTGGSVTDSFLVSGVAFKKTFSYAGFEQQPKKFNNPK
ICLLNIELELKAEKENAEIRIENPDDYKSIVDAEWELIYEKLRKIVESGANIVLSKLPIG
DLATQYFADRNIFCAGRVDAEDMKRVQKSTGAIVQTTVNGLTEDVLGTCNQFEEVQIGAE
RYNLFKDCPHSKSATIILRGGAEQFIAEAERSLNDAIMIVRRCMKANKIVPGGGAIELEI
SRLLRLHSRKTEGKIQLVINAFAKALEVIPRTIADNAGHDSIQVLNKLRQKHAIETEQSR
NFGVDINAADGIGNNYENFVWEPIVVRKNALSAATEAACTILSIDETVRNPKSEQPKAPP
GGLRRGGPQGMAGLAKNAKLGK