Identifiers and Description

Gene Model Identifier

TTHERM_00499440

Standard Name

TGP3 (Tetrahymena G-DNA binding Protein )

Aliases

PreTt07987 | 63.m00165 | 3716.m00019

Description

TGP3 G-quartet DNA-binding protein putative; G-quartet DNA binding protein; knockout strain shows increased occurrence of extra micronuclei; not essential for growth

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• nucleus (IDA) | GO:0005634

Molecular Function

• G-quadruplex DNA binding (IDA) | GO:0051880

Biological Process

• nuclear division (IMP) | GO:0000280

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_09688.1	5.001630449142324e-150
	Description: hypothetical protein (363 aa)
WormBase	WBGene00006840	5.001630449142324e-150
	Description: locus:unc-116 Kinesin heavy chain status:Confirmed UniProt:P34540 protein_id:CCD73193.1

General Information

No Data fetched for General Information

Associated Literature

1. Ref:10908364: Lu Q, Henderson E (2000) Two Tetrahymena G-DNA-binding proteins, TGP1 and TGP3, share novel motifs and may play a role in micronuclear division. Nucleic acids research 28(15):2993-3001

Sequences

>TTHERM_00499440(coding)
ATGGCTGAATAAGTTACTAACAACTAAGTCTCTCCTCAAGGAGAACAAAAACCTAAGGTA
TAAAAGAGACCAAGAACTGTTCAATTAGAATCTAAGGATCCTGTTAAGATTGCTGATCTC
TAACCCAGAAACAACAATTCTAACTTTGTTGGAAAGGTTATTGAAGTTTAAGTCTTAGAA
AAAGGCAATAACAAATAAGGCAATCCTAGAAAATTCCTTAAGGGTCTTATTGGTGATGAT
ACTGGTGTTGTCAGATTTGATTTGGCTGTTAAGAACGATGTCGTCTTTAAGGTAGATGAT
GTCGTCAGCTTCGATAAAGCTATGAACAAGGTAAACAAGGATGGTCACCACTACATTGAA
GTCAAGAGATTCGGTAAATACGAAATCACCAACGGCTCTATTGCCGCTGTTAAAACAGAT
AACAACATCTCAACAAAGATAATTCCTCCTCTTCCTGAAGGTGAAAAGAAGTAGAAGATT
ATTAAAAAAAGCAACAATAAGTAGAACAACAATGGTAAAGTTAACAACAACAACAATAAC
GGTGATAACAACACAAACAATAATGGTAACAAAATGAATAACCGCCCTTACAAAAAATAA
AACTACAATTAATAAAGAAAGACTAACAACAACAACAACAACAATAGCAACAACAACACT
AACAACTCTTAGAATTTCAAAAATTACAAATAAAAGCCTAAGAGATTCCACTAAGCTTTA
CTCACTCCTATCAAGAATCTTAAGCCTGGTTAAAACGGTTAAACTGTTAAAGGAAAAGTT
TTCGATGTTTAATCCTACTAAAAGACCATCAAGAATAGAGAAGCTACTTTCTTCAAGGGT
AGAGTTGCTGATGACACTGCAAATATTAATTTTGACTTCATGATGAAAGAAAAGACCATT
TCTGAAGGTGATATGGTTATCTTCACCAACATTATGAATAAGGTTTCAGAAACTGGCCAT
CACTACATCGTAGTCGGCAAGTACGGAAATTACAGTGTCTTGAATGAAAAATAGATCAAC
ATTAATGAATAAGAAAACAAGTCATCTATTGAATACGCCATCAGCTCTTCTAATAATGCC
ACTAAACAATGA

>TTHERM_00499440(gene)
ATGGCTGAATAAGTTACTAACAACTAAGGTAAAAAAACAAACATTAATTGATTCATCTAT
CATTTGCAATTTAGATATTCGATTTTTTAATTTAACTGAAATAATGATTTATTTTATGAT
AATTAGTCTCTCCTCAAGGAGAACAAAAACCTAAGGTATAAAAGAGACCAAGAACTGTTC
AATTAGAATCTAAGGATCCTGTTAAGATTGCTGATCTCTAACCCAGAAACAACAATTCTA
ACTTTGTTGGAAAGGTACCTACTTTAATACATAGGATATTAAACTTAAAAAAATAGATGA
TCATTTAGGATATACTTTTTTGCCCTTTTCAATTTATATTTAATGTGTTTTAGCTAAATG
CCAAATCAAAAAAAGAAACAAAAAATAGAATAAAATATTTTTATTGCTTCTAAAAATTAA
TAAAACTATTTATTCTTAAAGGTTATTGAAGTTTAAGTCTTAGAAAAAGGCAATAACAAA
TAAGGCAATCCTAGAAAATTCCTTAAGGGTCTTATTGGTGATGATACTGGTGTTGTCAGA
TTTGATTTGGCTGTTAAGAACGATGTCGTCTTTAAGGTAGATGATGTCGTCAGCTTCGAT
AAAGCTATGAACAAGGTAAACAAGGATGGTCACCACTACATTGAAGTCAAGAGATTCGGT
AAATACGAAATCACCAACGGCGTAAATTATTGTTTTTTAAAAAATAACAAATCTTCTTCT
CCTTTCAAAATTTTGTTTTAAAAGGGGGAGAACAAATGTATAAAATTAAGTAAATTTTAT
AATATTAATTTTATACTTATTATTTAAAATAGTCTATTGCCGCTGTTAAAACAGATAACA
ACATCTCAACAAAGATAATTCCTCCTCTTCCTGAAGGTAAAAAATATAATTTGATATTTG
CAGTAAAGATATTTTGGTTGGATTGATACACTATGAATTTCATTCAAATTGCAAATATAG
CAAATGTTCATTTAATTTTCTTTGTTTTAATTTTATTACTTATAATTACAAATTAGGTGA
AAAGAAGTAGAAGATTATTAAAAAAAGCAACAATAAGTAGAACAACAATGGTAAAGTTAA
CAACAACAACAATAACGGTGATAACAACACAAACAATAATGGTAACAAAATGAATAACCG
CCCTTACAAAAAATAAAACTACAATTAATAAAGAAAGACTAACAACAACAACAACAACAA
TAGCAACAACAACACTAACAACTCTTAGAATTTCAAAAATTACAAATAAAAGCCTAAGAG
ATTCCACTAAGCTTTACTCACTCCTATCAAGAATCTTAAGCCTGGTTAAAACGGTTAAAC
TGTTAAAGGAAAAGTAAAGACTTTGTTTAGAAATGTTCAGATTATATAGATTTATAAAAC
AATTGAATTGAATCTAAGAAATTTTAATTTTAATTTATTTACCTTAATAGGTTTTCGATG
TTTAATCCTACTAAAAGACCATCAAGAATAGAGAAGCTACTTTCTTCAAGGGTAGAGTTG
CTGATGACACTGCAAATATTAATTTTGACTTCATGATGAAAGAAAAGACCATTTCTGAAG
GTGATATGGTTATCTTCACCAACATTATGAATAAGGTTTCAGAAACTGGCCATCACTACA
TCGTAGTCGGCAAGTACGGAAATTACAGTGTCTTGAATGTAAGCATATTTTTGAATAAAT
ATACATTCTGTCTGACTAATGAAAATTATTAAAAAATAGGAAAAATAGATCAACATTAAT
GAATAAGAAAACAAGTCATCTATTGAATACGCCATCAGCTCTTCTAATAATGCCACTAAA
CAATGA

>TTHERM_00499440(protein)
MAEQVTNNQVSPQGEQKPKVQKRPRTVQLESKDPVKIADLQPRNNNSNFVGKVIEVQVLE
KGNNKQGNPRKFLKGLIGDDTGVVRFDLAVKNDVVFKVDDVVSFDKAMNKVNKDGHHYIE
VKRFGKYEITNGSIAAVKTDNNISTKIIPPLPEGEKKQKIIKKSNNKQNNNGKVNNNNNN
GDNNTNNNGNKMNNRPYKKQNYNQQRKTNNNNNNNSNNNTNNSQNFKNYKQKPKRFHQAL
LTPIKNLKPGQNGQTVKGKVFDVQSYQKTIKNREATFFKGRVADDTANINFDFMMKEKTI
SEGDMVIFTNIMNKVSETGHHYIVVGKYGNYSVLNEKQININEQENKSSIEYAISSSNNA
TKQ