Identifiers and Description

Gene Model Identifier

TTHERM_00506900

Standard Name

TWI2 (Tetrahymena piWI 2 )

Aliases

PreTt10673 | 64.m00153 | 3723.m00018

Description

TWI2 piwi-like Twi9p protein; PAZ and Piwi Domain (PPD) protein; similar to the Piwi/Argonaute proteins; Piwi domain

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• ARC complex (IDA) | GO:0033167
• cytoplasm (IDA) | GO:0005737

Molecular Function

• siRNA binding (IDA) | GO:0035197

Domains

• ( PF02170 ) PAZ domain
• ( PF02171 ) Piwi domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:19656801: Couvillion MT, Lee SR, Hogstad B, Malone CD, Tonkin LA, Sachidanandam R, Hannon GJ, Collins K (2009) Sequence, biogenesis, and function of diverse small RNA classes bound to the Piwi family proteins of Tetrahymena thermophila. Genes & development 23(17):2016-32
2. Ref:12297043: Mochizuki K, Fine NA, Fujisawa T, Gorovsky MA (2002) Analysis of a piwi-related gene implicates small RNAs in genome rearrangement in tetrahymena. Cell 110(6):689-99

Sequences

>TTHERM_00506900(coding)
ATGCTTTAATAGTTGCCTAAAAGACCTCCTAAATCTTCAGCTTAAGATATCAGCAAAATA
TGCAAAAATATTAAGCTGCTCACTAACATGTTTACAATGTAAGTAGAAGCCCCCTAGTCT
TCTGATTCTGATGAACCTCAAGGATTTGTGAACAAAGTTCTTTGCCATTAGTATGATGTT
GAATTCTCTCCTAGTATTGCTGAGGACAACAGAAATCTAAGATACAAAATCTTTAAAGAA
GCACGCAGGAACATTGAATAAATCATTGGAAAATTCTCCTTTTCAGGAAAGTCTCTATTC
TCAATGAGAAATCTTAGCAAAGAAAAGATTAATAAAATCAAGAATATTGATGCAATCAAT
GTTGATGGACAAAAATTCTCTATCCTATTGAGGTTCACTAAAACTTTTGAAGTGAATGAT
GAATCTGCTTAAAATTTAGACAAGACCTCTCCAAACTTCAAAAAAGGTAATCAAGTCACT
TAGTTGCTCAATATCATCTTAAAGTCTATCATGCGTGATGAGAAGTTTTAGGAAATTGGA
AAGAATTCTAAGTTCTATAATGTTAACTCTAGGAATGAAATCGTAATCAAAGGCAGAGAC
GGAAATACTAGTGCCCTCGAAGCATATAAGGGATTCACTTTCAATGTCACTCCAACCTAA
GACAAACTTTACTTAATGGTTGACTACTGCAGCAGAATTATCAGAAAAGAAACTGCTTTA
GAATACTTAAAGAATAACAACAATTAATTGTCTGGTCTTTCAGTAATTACCAAATACAAT
AATTACCAAACTTACTTAATCGACAGAGTAGATGGCCAAAAAACACCTAGTTCTACTTTC
CTTAACTCCAAAACTAACACCTAAATTAGCTTCGCATAATACTATAAGGAGCGTTATAAT
ATTTAAATCAGAGACATGAGATAGCCCTTACTTGTTCACAAAAGAAAATATAGAGAGGCT
AATACTAACATCTAAAAGGTTGAGGAAGTTTATTTAATTCCTGAAATATGCAATATGACA
GGAATGACAGACGAATAACGTGAGAATTTCCAAGCAATGAAGGAAGTTGCTACTCACACC
AAGTTAACTCCTTAAGAAAGATATCAAAATTCTGTTAACAATTGCAGATTTTTAAGCAGC
AAAACAAGCTCCAGTGGAATTAGAATTGATGAAAGAAGCAATTTAATTGACGCTGTTTAA
TTAAGAGCTCCTAAAGTCACTCTAGGAGGTAATAAGACTGCTAATACTGATAGAGGTAAT
TTTGACATGAGAGCTCCTACCTTAGATAAAATCGAGTTTAAGGATTGGACTCTTATTTAT
AACCAAAAAGATGAGAGATCTGTGGATGGTTTCATAGACACTCTTAAGAAGGCTTCCTAG
ACATATGGAATTACTGTCAACGACCCTTTCTTTTTCGCCTAAAGAGATTGGAATGCTAAT
AGTTGGATTAAATCTCTAGATGAGGACTTTTCTAAGAATGACTTACCTTAATTTGTTTTG
AGTTTTGGTCAAGCTTAAAGCGGTTTATATTCTGGTCTGAAGAAATTTTTAACTTCAGAA
GCAGGAATTGAATCCTAGCATGTTAATCCAAGATCCCTCCAAAAGAACGGAATGAGTGTT
GCTTCAAAAATTGCTCTGCAAATTGCCTCTAAACTTGGTAGAAGAATCTGGTAAGTTGAA
ACCCCAACTGGAATTGATAAAAATACCATGATTATAGGTATTGAGACCAGCATGAAAAAG
ATTAAATAGTAGTAGGTTGTAGGTGTTGTTGCTTCCATCGACAAAGACTTTACCAAATAC
TTTTCTGATGTTGAAATTAGGAAAGACAATGATACTACTCTCCCTACTCTCTCTAAGATT
GTTACCAAAGCCATATAAGCTTATGTTAAAAATACCAAAAGTGTTCCTGCTGAAGTGATT
GTTTACAGATAAGGACTTGGTGAAGGTTAAATTCAATAGAGTTGTAACCTTGAAATTAAG
GCCATTTAGAATGGTTTTAGTAACTTCAAGAGCGATTTCAATCCACGTTTAGCCTTTTTC
TAGGTTAATAGAAAAATTGGACAAAAGTTCTATTAATCACCTTAAGGTGACAAAGGTGAA
GTCTCAAATCCTGCTTCAGGTACTATTGTAGCCTCTTAAGTTGTTTAGAACAACTTCGAA
TTCTTCATGGCTGCATAAAACTGCAATTCTGGTGTTTGTACACCCACTAAATACACCTGT
TTGTACAATAACACTAACTTAAAAGAAGATTAAATCTGGTAATTAACTTACTATCAAACT
TTCAATTACTATAACTGGCAAGGACCTGTAAGAGTACCTGCCGCTATGAAGTACGCAGAA
AAACTTGCTAAATTCGTAAGTGACACTATCTAAGAAGCTGCCAACGAAAACTTGACTAAC
AGTCTTTTCTACTTGTGA

>TTHERM_00506900(gene)
TAAAATCAAAATTTTGTTTTGATTAAAATTTCTATAAAAAGAGGTAGCAATACTCATTAT
CTTTATAATAATTTATATTCCTTTAAATACACTAAAAGAAAAAGTAAAAAATAAAGAAAT
GCTTTAATAGTTGCCTAAAAGACCTCCTAAATCTTCAGCTTAAGATATCAGCAAAATATG
CAAAAATATTAAGCTGCTCACTAACATGTTTACAATGTAAGTAGAAGCCCCCTAGTCTTC
TGATTCTGATGAACCTCAAGGATTTGTGAACAAAGTTCTTTGCCATTAGTATGATGTTGA
ATTCTCTCCTAGTATTGCTGAGGACAACAGAAATCTAAGATACAAAATCTTTAAAGAAGC
ACGCAGGAACATTGAATAAATCATTGGAAAATTCTCCTTTTCAGGAAAGTCTCTATTCTC
AATGAGAAATCTTAGCAAAGAAAAGATTAATAAAATCAAGAATATTGATGCAATCAATGT
TGATGGACAAAAATTCTCTATCCTATTGAGGTTCACTAAAACTTTTGAAGTGAATGATGA
ATCTGCTTAAAATTTAGACAAGACCTCTCCAAACTTCAAAAAAGGTAATCAAGTCACTTA
GTTGCTCAATATCATCTTAAAGTCTATCATGCGTGATGAGAAGTTTTAGGAAATTGGAAA
GAATTCTAAGTTCTATAATGTTAACTCTAGGAATGAAATCGTAATCAAAGGCAGAGACGG
AAATACTAGTGCCCTCGAAGCATATAAGGGATTCACTTTCAATGTCACTCCAACCTAAGA
CAAACTTTACTTAATGGTTGACTACTGCAGCAGAATTATCAGAAAAGAAACTGCTTTAGA
ATACTTAAAGAATAACAACAATTAATTGTCTGGTCTTTCAGTAATTACCAAATACAATAA
TTACCAAACTTACTTAATCGACAGAGTAGATGGCCAAAAAACACCTAGTTCTACTTTCCT
TAACTCCAAAACTAACACCTAAATTAGCTTCGCATAATACTATAAGGAGCGTTATAATAT
TTAAATCAGAGACATGAGATAGCCCTTACTTGTTCACAAAAGAAAATATAGAGAGGCTAA
TACTAACATCTAAAAGGTTGAGGAAGTTTATTTAATTCCTGAAATATGCAATATGACAGG
AATGACAGACGAATAACGTGAGAATTTCCAAGCAATGAAGGAAGTTGCTACTCACACCAA
GTTAACTCCTTAAGAAAGATATCAAAATTCTGTTAACAATTGCAGATTTTTAAGCAGCAA
AACAAGCTCCAGTGGAATTAGAATTGATGAAAGAAGCAATTTAATTGACGCTGTTTAATT
AAGAGCTCCTAAAGTCACTCTAGGAGGTAATAAGACTGCTAATACTGATAGAGGTAATTT
TGACATGAGAGCTCCTACCTTAGATAAAATCGAGTTTAAGGATTGGACTCTTATTTATAA
CCAAAAAGATGAGAGATCTGTGGATGGTTTCATAGACACTCTTAAGAAGGCTTCCTAGAC
ATATGGAATTACTGTCAACGACCCTTTCTTTTTCGCCTAAAGAGATTGGAATGCTAATAG
TTGGATTAAATCTCTAGATGAGGACTTTTCTAAGAATGACTTACCTTAATTTGTTTTGAG
TTTTGGTCAAGCTTAAAGCGGTTTATATTCTGGTCTGAAGAAATTTTTAACTTCAGAAGC
AGGAATTGAATCCTAGCATGTTAATCCAAGATCCCTCCAAAAGAACGGAATGAGTGTTGC
TTCAAAAATTGCTCTGCAAATTGCCTCTAAACTTGGTAGAAGAATCTGGTAAGTTGAAAC
CCCAACTGGAATTGATAAAAATACCATGATTATAGGTATTGAGACCAGCATGAAAAAGAT
TAAATAGTAGTAGGTTGTAGGTGTTGTTGCTTCCATCGACAAAGACTTTACCAAATACTT
TTCTGATGTTGAAATTAGGAAAGACAATGATACTACTCTCCCTACTCTCTCTAAGATTGT
TACCAAAGCCATATAAGCTTATGTTAAAAATACCAAAAGTGTTCCTGCTGAAGTGATTGT
TTACAGATAAGGACTTGGTGAAGGTTAAATTCAATAGAGTTGTAACCTTGAAATTAAGGC
CATTTAGAATGGTTTTAGTAACTTCAAGAGCGATTTCAATCCACGTTTAGCCTTTTTCTA
GGTTAATAGAAAAATTGGACAAAAGTTCTATTAATCACCTTAAGGTGACAAAGGTGAAGT
CTCAAATCCTGCTTCAGGTACTATTGTAGCCTCTTAAGTTGTTTAGAACAACTTCGAATT
CTTCATGGCTGCATAAAACTGCAATTCTGGTGTTTGTACACCCACTAAATACACCTGTTT
GTACAATAACACTAACTTAAAAGAAGATTAAATCTGGTAATTAACTTACTATCAAACTTT
CAATTACTATAACTGGCAAGGACCTGTAAGAGTACCTGCCGCTATGAAGTACGCAGAAAA
ACTTGCTAAATTCGTAAGTGACACTATCTAAGAAGCTGCCAACGAAAACTTGACTAACAG
TCTTTTCTACTTGTGAGAAAACATCAATTAATATTCAATAATCAATCAATCAATCACTGC
TTAAATAATCAATCACATTCAAATCATTTTATTTATTTATTTCCTACTTTTCTCTTAAAG
TGATATGAATGAATGACTGATATTTTAGCGATATATATATTTTATAATTAAATTGATTAA
ATAATTTACATTTACATACCTTTTCCCATATATATTTATATATTTTTCATGTAATTGTAT
TTTTGCAATTAATTTAATTACCTTAAAAAAATCTATT

>TTHERM_00506900(protein)
MLQQLPKRPPKSSAQDISKICKNIKLLTNMFTMQVEAPQSSDSDEPQGFVNKVLCHQYDV
EFSPSIAEDNRNLRYKIFKEARRNIEQIIGKFSFSGKSLFSMRNLSKEKINKIKNIDAIN
VDGQKFSILLRFTKTFEVNDESAQNLDKTSPNFKKGNQVTQLLNIILKSIMRDEKFQEIG
KNSKFYNVNSRNEIVIKGRDGNTSALEAYKGFTFNVTPTQDKLYLMVDYCSRIIRKETAL
EYLKNNNNQLSGLSVITKYNNYQTYLIDRVDGQKTPSSTFLNSKTNTQISFAQYYKERYN
IQIRDMRQPLLVHKRKYREANTNIQKVEEVYLIPEICNMTGMTDEQRENFQAMKEVATHT
KLTPQERYQNSVNNCRFLSSKTSSSGIRIDERSNLIDAVQLRAPKVTLGGNKTANTDRGN
FDMRAPTLDKIEFKDWTLIYNQKDERSVDGFIDTLKKASQTYGITVNDPFFFAQRDWNAN
SWIKSLDEDFSKNDLPQFVLSFGQAQSGLYSGLKKFLTSEAGIESQHVNPRSLQKNGMSV
ASKIALQIASKLGRRIWQVETPTGIDKNTMIIGIETSMKKIKQQQVVGVVASIDKDFTKY
FSDVEIRKDNDTTLPTLSKIVTKAIQAYVKNTKSVPAEVIVYRQGLGEGQIQQSCNLEIK
AIQNGFSNFKSDFNPRLAFFQVNRKIGQKFYQSPQGDKGEVSNPASGTIVASQVVQNNFE
FFMAAQNCNSGVCTPTKYTCLYNNTNLKEDQIWQLTYYQTFNYYNWQGPVRVPAAMKYAE
KLAKFVSDTIQEAANENLTNSLFYL