Identifiers and Description

Gene Model Identifier

TTHERM_00506910

Standard Name

TWI4 (Tetrahymena piWI 4)

Aliases

PreTt10674 | 64.m00154 | 3723.m00019

Description

piwi-like Twi9p protein; Piwi domain containing protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF02170 ) PAZ domain
• ( PF02171 ) Piwi domain
• ( TIGR00193 ) urease, gamma subunit

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_14909.1	9.997093137033517e-262
	Description: piwi domain-containing protein (808 aa)
Tetrahymena borealis	EI9_05970.1	9.997093137033517e-262
	Description: hypothetical protein (145 aa)
Oxytricha	Contig16116.0.g20	6.001309080488961e-82
	Description: Piwi domain
WormBase	WBGene00004178	1.0000310450948521e-65
	Description: locus:prg-1 status:Confirmed UniProt:P90786 protein_id:CAA98113.1
WormBase	WBGene00011352	1.0000310450948521e-65
	Description: locus:rskn-1 Putative ribosomal protein S6 kinase alpha-1 status:Partially_confirmed UniProt:Q21734 protein_id:CAB02301.2
DictyBase	DDB_G0276299	3.9989468726312675e-65
	Description: agnA on chromosome: 2 position 6579134 to 6582276
Stentor Coeruleus	SteCoe_1413	4.0795586671775603e-41
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:19656801: Couvillion MT, Lee SR, Hogstad B, Malone CD, Tonkin LA, Sachidanandam R, Hannon GJ, Collins K (2009) Sequence, biogenesis, and function of diverse small RNA classes bound to the Piwi family proteins of Tetrahymena thermophila. Genes & development 23(17):2016-32

Sequences

>TTHERM_00506910(coding)
ATGCTTTAATAGTTACCTAGTAGACCTCCTATATCATCTACTTAAGAGATCAGCCAAATA
TGCAAAAATATTAAACTGCTTACAAATATGTTTGCTATGTAAGTAGAAGCCACCTAGTCT
TCTGATTCTGATGGACCTCAAGGCTTTGTTAACAAAGTTGTTTGCTATCAATATGATGTT
GTATTCTCTCCTGATATTGCTGAGGACAATAGAAATCTAAGATACAAAATCTTTAAAGAA
GCACGCAGGAACATTGAATAACTCATCGGAAAATTCTCCTTTTCAGGAATGTCTCTATTC
TCAATGAGAAAACTTAGCTAAGATAAGATTAATAAAATCAAGAATAATATTGATGCAATC
ATTGTAGACAAACAAAAATACTCTATCCATTTGGTGTTCACAAAAAGCTTTGAAGTAAAT
GACGAATCTGCTTAAAATTTAGACAAGACCTCTCCAAACTTCAAAAAAGGTAATCAAGTC
ACTTAGTTGCTCAATATCATCTTAAAGTCTATTATGCGTGATGAGAAATTTTTAGAAATC
GGAAAGAATTCTAAGTTCTATGAAGTTAACTCTAAAAGTGACATAATTATCAAAAGTAGA
GAAGGTTCTACTAGTGGTCTCGAAGCCTACAAAGGATTCACTTTCAACGTCACTCCAACC
TAAGACAAAATTTACTTAATGGTTGACTACTGCAGTAGAATTATCAGAAAAGAAACTGCT
TTAGAATACTTAAAGAATAACAACAATTAATTATCTGGTCTCTCAGTAATTACCAAATAC
AATAATTACCAAACTTACTTAATCGATAAAGTAGATGATAAAAAAACACCTAGTTCTACT
TTCCTCAACTCCAAAACTAACATTCAAATTAGCTTCGCCTAATACTACAAGGAACGTTAT
AATATTTAAATTAGAGACATGAAATAACCCTTGCTTGTTCACAAAAGAAAATACAGAGAG
GCTAATACTAATATCTAAAAGGTTGAAGAAGTTTATTTAATTCCTGAATTATGCAATATG
ACAGGAATGACAGACGAATAACGTGAGAATTTCCAAGCAATGAAGGAAGTTGCTACTCAT
ACTAAGCTTACTCCTTAAGAAAGATATCAAAATTCTATTAATAATTGTAGATTTTTAAGC
AAAAAAACAAGTTCAAGTGGAATTAAAATTGATGAAAGAAGCAATTTAATAGATGCTGTT
TAATTAAGAACTCCTAAAGTCACTCTAGGAGGTAATAAGACTGCTAATACTGATAGAGGT
AATTTTGACATGAGAACTCCTACCTTAGATAAAATCGAGTTTAAGGATTGGTCTCTTATT
TATAACCAAAAAGATGAGAAATATGTGGATGATTTCGTAGACACTCTTAAGAAGGCTTCC
TAGACATATGGAATAATTGTCAACGATCCTTACTTCTTCGCCGAAAGAGATTCGAATGCT
AATAATTGGATTAAATCTCTGGATGAGGACTTTTCCAAAAATGACTTACCTCAATTTGTT
TTGAGTTTCGGTCAAGTTAATTCTGGATTTTACTCTAGTTTAAAGAAATTTTTAACTTCA
GAAGCAGGAATAGAATCCCAGCATGTTACTCCAAAATCTCTTCAAAAGAACGGAATGAGT
GTGGCTTCAAAAATTGCTTTGTAAATTGCCTCTAAGCTTGGTAGAAGAATTTGGTAAGTT
GAAACACCTCGTGGAATTGATAAAAATACCATGATTATAGGTATTGAGACCAGCATGAAA
AAGGTTAAATAGTAGTAGGTTGTAGGTGTTGTTGCTTCCATCGACAAAGACTTTACCAAA
TACTTTTCTGATGTTGAAATTAGAAAAGACAATGATACTACTCTCCCTACTCTCTCTAAG
ATTGTTACCAAAGCCATATAAGCTTATGTTAAAAATACCAAAAGTGTTCCTGCTGAAGTC
ATTGTTTACAGATAAGGACTTGGTGAAGGTTAAATTCAATAGAGTTTTAACCTTGAAATT
AAGGCCATTTAGAATGGTTTTAGTAACTTCAAGAACGATTTCAATCCTCATTTAGCCTTT
TTCTAGGTTAATAGAAAAATTGGCCAAAAGTTCTATTAATCGCCTTAAGGTGATAAAGTA
GAAGTCTCAAATCCTGCTTCAGGTACTATTGTAGCCTCTTAAGTTGTTTAGAACAACTTC
GAATTCTTCATGGCTGCATAACACTGCAATTCTGGTGTTTGTACACCCACTAAATACACC
TGTTTGTACAACAACACTAACTTAAAAGAAGATTAAATCTGGTAATTAACTTACTATCAA
ACTTTCAATTACTATAACTGGCAAGGACCTGTAAGAGTGCCTGCTGCTATGAAGTACGCA
GAAAAACTTGCTAAATTCGTAAGTGACACTATCTAAGAAGCAGCCAATGAAAATTTGACT
AATAGTCTTTTCTACTTGTGA

>TTHERM_00506910(gene)
ATGCTTTAATAGTTACCTAGTAGACCTCCTATATCATCTACTTAAGAGATCAGCCAAATA
TGCAAAAATATTAAACTGCTTACAAATATGTTTGCTATGTAAGTAGAAGCCACCTAGTCT
TCTGATTCTGATGGACCTCAAGGCTTTGTTAACAAAGTTGTTTGCTATCAATATGATGTT
GTATTCTCTCCTGATATTGCTGAGGACAATAGAAATCTAAGATACAAAATCTTTAAAGAA
GCACGCAGGAACATTGAATAACTCATCGGAAAATTCTCCTTTTCAGGAATGTCTCTATTC
TCAATGAGAAAACTTAGCTAAGATAAGATTAATAAAATCAAGAATAATATTGATGCAATC
ATTGTAGACAAACAAAAATACTCTATCCATTTGGTGTTCACAAAAAGCTTTGAAGTAAAT
GACGAATCTGCTTAAAATTTAGACAAGACCTCTCCAAACTTCAAAAAAGGTAATCAAGTC
ACTTAGTTGCTCAATATCATCTTAAAGTCTATTATGCGTGATGAGAAATTTTTAGAAATC
GGAAAGAATTCTAAGTTCTATGAAGTTAACTCTAAAAGTGACATAATTATCAAAAGTAGA
GAAGGTTCTACTAGTGGTCTCGAAGCCTACAAAGGATTCACTTTCAACGTCACTCCAACC
TAAGACAAAATTTACTTAATGGTTGACTACTGCAGTAGAATTATCAGAAAAGAAACTGCT
TTAGAATACTTAAAGAATAACAACAATTAATTATCTGGTCTCTCAGTAATTACCAAATAC
AATAATTACCAAACTTACTTAATCGATAAAGTAGATGATAAAAAAACACCTAGTTCTACT
TTCCTCAACTCCAAAACTAACATTCAAATTAGCTTCGCCTAATACTACAAGGAACGTTAT
AATATTTAAATTAGAGACATGAAATAACCCTTGCTTGTTCACAAAAGAAAATACAGAGAG
GCTAATACTAATATCTAAAAGGTTGAAGAAGTTTATTTAATTCCTGAATTATGCAATATG
ACAGGAATGACAGACGAATAACGTGAGAATTTCCAAGCAATGAAGGAAGTTGCTACTCAT
ACTAAGCTTACTCCTTAAGAAAGATATCAAAATTCTATTAATAATTGTAGATTTTTAAGC
AAAAAAACAAGTTCAAGTGGAATTAAAATTGATGAAAGAAGCAATTTAATAGATGCTGTT
TAATTAAGAACTCCTAAAGTCACTCTAGGAGGTAATAAGACTGCTAATACTGATAGAGGT
AATTTTGACATGAGAACTCCTACCTTAGATAAAATCGAGTTTAAGGATTGGTCTCTTATT
TATAACCAAAAAGATGAGAAATATGTGGATGATTTCGTAGACACTCTTAAGAAGGCTTCC
TAGACATATGGAATAATTGTCAACGATCCTTACTTCTTCGCCGAAAGAGATTCGAATGCT
AATAATTGGATTAAATCTCTGGATGAGGACTTTTCCAAAAATGACTTACCTCAATTTGTT
TTGAGTTTCGGTCAAGTTAATTCTGGATTTTACTCTAGTTTAAAGAAATTTTTAACTTCA
GAAGCAGGAATAGAATCCCAGCATGTTACTCCAAAATCTCTTCAAAAGAACGGAATGAGT
GTGGCTTCAAAAATTGCTTTGTAAATTGCCTCTAAGCTTGGTAGAAGAATTTGGTAAGTT
GAAACACCTCGTGGAATTGATAAAAATACCATGATTATAGGTATTGAGACCAGCATGAAA
AAGGTTAAATAGTAGTAGGTTGTAGGTGTTGTTGCTTCCATCGACAAAGACTTTACCAAA
TACTTTTCTGATGTTGAAATTAGAAAAGACAATGATACTACTCTCCCTACTCTCTCTAAG
ATTGTTACCAAAGCCATATAAGCTTATGTTAAAAATACCAAAAGTGTTCCTGCTGAAGTC
ATTGTTTACAGATAAGGACTTGGTGAAGGTTAAATTCAATAGAGTTTTAACCTTGAAATT
AAGGCCATTTAGAATGGTTTTAGTAACTTCAAGAACGATTTCAATCCTCATTTAGCCTTT
TTCTAGGTTAATAGAAAAATTGGCCAAAAGTTCTATTAATCGCCTTAAGGTGATAAAGTA
GAAGTCTCAAATCCTGCTTCAGGTACTATTGTAGCCTCTTAAGTTGTTTAGAACAACTTC
GAATTCTTCATGGCTGCATAACACTGCAATTCTGGTGTTTGTACACCCACTAAATACACC
TGTTTGTACAACAACACTAACTTAAAAGAAGATTAAATCTGGTAATTAACTTACTATCAA
ACTTTCAATTACTATAACTGGCAAGGACCTGTAAGAGTGCCTGCTGCTATGAAGTACGCA
GAAAAACTTGCTAAATTCGTAAGTGACACTATCTAAGAAGCAGCCAATGAAAATTTGACT
AATAGTCTTTTCTACTTGTGA

>TTHERM_00506910(protein)
MLQQLPSRPPISSTQEISQICKNIKLLTNMFAMQVEATQSSDSDGPQGFVNKVVCYQYDV
VFSPDIAEDNRNLRYKIFKEARRNIEQLIGKFSFSGMSLFSMRKLSQDKINKIKNNIDAI
IVDKQKYSIHLVFTKSFEVNDESAQNLDKTSPNFKKGNQVTQLLNIILKSIMRDEKFLEI
GKNSKFYEVNSKSDIIIKSREGSTSGLEAYKGFTFNVTPTQDKIYLMVDYCSRIIRKETA
LEYLKNNNNQLSGLSVITKYNNYQTYLIDKVDDKKTPSSTFLNSKTNIQISFAQYYKERY
NIQIRDMKQPLLVHKRKYREANTNIQKVEEVYLIPELCNMTGMTDEQRENFQAMKEVATH
TKLTPQERYQNSINNCRFLSKKTSSSGIKIDERSNLIDAVQLRTPKVTLGGNKTANTDRG
NFDMRTPTLDKIEFKDWSLIYNQKDEKYVDDFVDTLKKASQTYGIIVNDPYFFAERDSNA
NNWIKSLDEDFSKNDLPQFVLSFGQVNSGFYSSLKKFLTSEAGIESQHVTPKSLQKNGMS
VASKIALQIASKLGRRIWQVETPRGIDKNTMIIGIETSMKKVKQQQVVGVVASIDKDFTK
YFSDVEIRKDNDTTLPTLSKIVTKAIQAYVKNTKSVPAEVIVYRQGLGEGQIQQSFNLEI
KAIQNGFSNFKNDFNPHLAFFQVNRKIGQKFYQSPQGDKVEVSNPASGTIVASQVVQNNF
EFFMAAQHCNSGVCTPTKYTCLYNNTNLKEDQIWQLTYYQTFNYYNWQGPVRVPAAMKYA
EKLAKFVSDTIQEAANENLTNSLFYL