Identifiers and Description

Gene Model Identifier

TTHERM_00519760

Standard Name

AOS1 (Activation Of Smt3p 1 )

Aliases

PreTt10771 | 64.m00251 | 3723.m00104

Description

AOS1 ThiF family protein; ThiF family protein; ortholog of AOS1 in S. cerevisiae

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF00899 ) ThiF family
• ( TIGR00449 ) tRNA-guanine transglycosylases, various specificities
• ( TIGR02354 ) thiamine biosynthesis protein ThiF
• ( TIGR02355 ) molybdopterin synthase sulfurylase MoeB
• ( TIGR02356 ) thiazole biosynthesis adenylyltransferase ThiF

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_15424.1	9.997093137033517e-262
	Description: ThiF family protein (373 aa)
Tetrahymena borealis	EI9_05996.1	9.997093137033517e-262
	Description: hypothetical protein (2819 aa)
Oxytricha	Contig11259.0.g51	1.9996410647472548e-29
	Description: ThiF family
SGD	YPR180W	2.999534586690157e-23
	Description: AOS1 Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability
DictyBase	DDB_G0279641	4.0009493637353324e-18
	Description: sae1 on chromosome: 3 position 2354365 to 2355712
WormBase	WBGene00000142	0.000000004999139696582238
	Description: locus:aos-1 SUMO-activating enzyme subunit aos-1 status:Confirmed UniProt:Q17820 protein_id:CAA96591.1

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00519760(coding)
ATGGAAGTAGAATAAGTTTAGGAATAGTCTTAAAATTAAAAAGAAATTTCAAATGAAGAA
CTTTAAGTCTATGATAGACAAAGGTTCATAGGAGTTGAAGTATAAAAAAGATTATTAAAC
GCCAAAGTTTTTATCACTCCTGCAAATGGTGTTAACACAGAATTAGCAAAAAATTTAATT
CTTTGCGGTACAAATATATCAATTGCTGATAACGAGATTGTCAACTAGGATGATGTTGAA
ACAAATTTCCTTATTGCACCTCACGATTTAGGAAAAATAAGAGGTGAAGTTGTTAAAGCT
AAGCTATAAGATATGAATCCAATGGTTAAAATAGACCTTTATCAAACATTTGATATTAAG
TCATTTTACTAAAAATATATTCTTGAAAACAATGTTGATTGTTCTTTTACTAAAGAATTC
TTCAATTAATTCAATATAATAACTTCTTCAACTCCAATCTTTAAAGAAATGGAATTGTAT
GACGAAATAAGTCACTTTTTAAATATTCCTTATTACAACCAACTTTGCTGTGGTCTTTAT
GGTTTCTTTTATGTTTCTCTTGGCTCTCTATTCGAATTGACACAAGCTAAACCTAAGATA
TAAAAGACAAAAATTGTTTAAGGAAAACTTGTCAAAGAACCTATTTTATTTGAGTATTTC
CATAAAGTTAGCTTGAAATCAGAAAAATTAAAAAATTTCCTTGGAACAAATCCCAGAGGA
TCAAAGCCAGTATACCATGCAATTCAAATGATGAAAAGAGCAGAAGATTTAAATTTAAGA
TATGATCCTTACAATCACAGTGAGGAAAACTAAAAGGTTTTAGAATAAATAGTAGAGCTT
GCTCAAGAAAAAATTAAAAATGAGGAAGATAGAGAATTCTATACAAATTTTGCAAAATTC
TATGGAATTGAACACTGTCCAGTATACTCAGTTATTGGAAGTGTAGCAAGCCAAGAATTT
ATCAAAGTTATTGCCAAGGATAAAATGCCTGCCCTTAATTGGTTTGTATATGATAGCTAA
ATTGGATATGGTAAAATAGAAAGCTAAACTGATAAAATAGATGCAACATATGTAGATTTA
CCTGAGTTAACAAGAAAAGTTGAAGAATAGCAAGAATGA

>TTHERM_00519760(gene)
ATGGAAGTAGAATAAGTTTAGGAATAGTCTTAAAATTAAAAAGAAATTTCAAATGAAGAA
CTTTAAGTCTATGATAGACAAAGGTTCATAGGAGTTGAAGTATAAAAAAGGTAATCTTTG
CAAATTATCATTTAAAAAAAGTAATTTATCTAATTTATCAAGATTATTAAACGCCAAAGT
TTTTATCACTCCTGCAAATGGTGTTAACACAGAATTAGCAAAAAATTTAATTCTTTGCGG
TACAAATATATCAATTGCTGATAACGAGATTGTCAACTAGGATGATGTTGAAACAAATTT
CCTTATTGCACCTCACGATTTAGGAAAAATAGTAATATTAAAAGAAATATCAATGCGCAA
TTTTTCTTATGAAAATTTATTTTGAAAATAGAGAGGTGAAGTTGTTAAAGCTAAGCTATA
AGATATGAATCCAATGGTTAAAATAGACCTTTATCAAACATTTGATATTAAGTCATTTTA
CTAAAAATATATTCTTGAAAACAATGTTGATTGTTCTTTTACTAAAGAATTCTTCAATTA
ATTCAATATAATAACTTCTTCAACTCCAATCTTTAAAGAAATGGTAAGTTAAATAAATAT
AAAACGAAATTTTATTTAAAAATGTTATTAATTAAATAATAAGGAATTGTATGACGAAAT
AAGTCACTTTTTAAATATTCCTTATTACAACCAACTTTGCTGTGGTCTTTATGGTTTCTT
TTATGTTTCTCTTGGCTCTCTATTCGAATTGACACAGTAATCAATTAATAAATAAATTAT
TTAATTAAATATCAAAGATATGCTTTTAAATTAAAGAAATAATATATCTTATTCTAACTT
TAAATAAATAAAAAAATAAAAGAGCTAAACCTAAGATATAAAAGACAAAAATTGTTTAAG
GAAAACTTGTCAAAGAACCTATTTTATTTGAGTATTTCCATAAAGTTAGCTTGAAATCAG
AAAAATTAAAAAATTTCCTTGGAACAAATCCCAGAGGATCAAAGCCAGTATACCATGCAA
TTCAAAGTAAATCAACTTTTCTTTAAATTATTATAATTAAATATATTGTGTCTACTTATT
TAAGTGATGAAAAGAGCAGAAGATTTAAATTTAAGATATGATCCTTACAATCACAGTGAG
GAAAACTAAAAGGTTTTAGAATAAATAGTAGAGCTTGCTCAAGAAAAAATTAAAAATGAG
GAAGATAGAGAATTCTATACAAATTTTGCAAAATTCTATGGAATTGAACACTGTCCAGTA
TACTCAGTTATTGGAAGTGTAGCAAGCCAAGAATTTATCAAAGTTATTGCCAGTAAGATT
CGTTTTATAATTTATTGAATTTGAAATATTTTTTAAAATTAATGTCTATTTTATATATAA
ATTTAAGAGGATAAAATGCCTGCCCTTAATTGGTTTGTATATGATAGCTAAATTGGATAT
GGTAAAATAGAAAGCTAAACTGATAAAATAGATGCAACATATGTAGATTTACCTGAGTTA
ACAAGAAAAGTTGAAGAATAGCAAGAATGA

>TTHERM_00519760(protein)
MEVEQVQEQSQNQKEISNEELQVYDRQRFIGVEVQKRLLNAKVFITPANGVNTELAKNLI
LCGTNISIADNEIVNQDDVETNFLIAPHDLGKIRGEVVKAKLQDMNPMVKIDLYQTFDIK
SFYQKYILENNVDCSFTKEFFNQFNIITSSTPIFKEMELYDEISHFLNIPYYNQLCCGLY
GFFYVSLGSLFELTQAKPKIQKTKIVQGKLVKEPILFEYFHKVSLKSEKLKNFLGTNPRG
SKPVYHAIQMMKRAEDLNLRYDPYNHSEENQKVLEQIVELAQEKIKNEEDREFYTNFAKF
YGIEHCPVYSVIGSVASQEFIKVIAKDKMPALNWFVYDSQIGYGKIESQTDKIDATYVDL
PELTRKVEEQQE