Identifiers and Description

Gene Model Identifier

TTHERM_00527180

Standard Name

GRL1 ( GRanule Lattice)

Aliases

p40 | PreTt06450 | 66.m00249 | 3722.m00106

Description

GRL1 granule lattice protein; hypothetical protein

Genome Browser (Macronucleus)

Full Screen View


Genome Browser (Micronucleus)

Full Screen View

External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:15958493: Cowan AT, Bowman GR, Edwards KF, Emerson JJ, Turkewitz AP (2005) Genetic, genomic, and functional analysis of the granule lattice proteins in Tetrahymena secretory granules. Molecular biology of the cell 16(9):4046-60
  2. Ref:14690495: Turkewitz AP (2004) Out with a bang! Tetrahymena as a model system to study secretory granule biogenesis. Traffic (Copenhagen, Denmark) 5(2):63-8
  3. Ref:15537088: Jacobs ME, Cortezzo DE, Klobutcher LA (2004) Assessing the effectiveness of coding and non-coding regions in antisense ribosome inhibition of gene expression in Tetrahymena. The Journal of eukaryotic microbiology 51(5):536-41
  4. Ref:12435750: Bradshaw NR, Chilcoat ND, Verbsky JW, Turkewitz AP (2003) Proprotein processing within secretory dense core granules of Tetrahymena thermophila. The Journal of biological chemistry 278(6):4087-95
  5. Ref:11779800: Bowman GR, Turkewitz AP (2001) Analysis of a mutant exhibiting conditional sorting to dense core secretory granules in Tetrahymena thermophila. Genetics 159(4):1605-16
  6. Ref:9450970: Verbsky JW, Turkewitz AP (1998) Proteolytic processing and Ca2+-binding activity of dense-core vesicle polypeptides in Tetrahymena. Molecular biology of the cell 9(2):497-511
  7. Ref:9380694: Haddad A, Turkewitz AP (1997) Analysis of exocytosis mutants indicates close coupling between regulated secretion and transcription activation in Tetrahymena. Proceedings of the National Academy of Sciences of the United States of America 94(20):10675-80
  8. Ref:8991090: Chilcoat ND, Melia SM, Haddad A, Turkewitz AP (1996) Granule lattice protein 1 (Grl1p), an acidic, calcium-binding protein in Tetrahymena thermophila dense-core secretory granules, influences granule size, shape, content organization, and release but not protein sorting or condensation. The Journal of cell biology 135(6 Pt 2):1775-87
  9. Ref:2065648: Turkewitz AP, Madeddu L, Kelly RB (1991) Maturation of dense core granules in wild type and mutant Tetrahymena thermophila. The EMBO journal 10(8):1979-87

Sequences 

>TTHERM_00527180(coding)
ATGAATAAGAAATTATTAGTTGTCCTTTTCGGATTCCTCGCTTTGGCTGCTGCTACCAAC
CAAAGTGAAGAAGAAGGTTCTTACACCATCGATCAAGCTGCAAATCTTTTAAATGACTTA
CTTGCAGATTCTCAACAAAATTTGAGCGATCTCCAAGCTGCATGGGCCAATAAGGAACCT
CTTTTACAAGGTGTTATTGCTGGACTTGAAAGCGATCTTGCCAACAAGTAAGCTGAATGC
GCTGATCTCTAAGGTACCCTTGATGCTGATTAAGCTTCCCTCGATGAAGCTGAAGCATAC
GTTGCCTGGTTATAAGACAGAATTGCTGCTAACCATAAGCAAATTGACGACTTACTCAAC
AGAAGATGTCAACAAAACGGTAACTACATTGAAGGTCTTAAGAACGACAAGCTCGCTCTT
GCTCTCTTATAATTCCTTGAAGCCTAAATTCAAAACAAGGAATCCTTCTCTTTCCTCCAA
AAGAAGAACTTCATGAAGAAACTCACCCGTTTCTTGAGCATCTACAAAACTGGTAACTAT
TAATAACTCGCTCTCCTTGAAAAGGAATACGTTAACGCTGATGACTACTCAGTTAATCCC
GACTACTCTACTGGTGACAGAACTGCTGACGAAATCGGATCTGGTCACATTGATAACGAC
AAGGGTGATATCGATGTTGCTGACTTCTAAGAAGGTGAAAGAAAGGGATGGTACTAAGTC
AAATAAGAATTATTAGACCTCTTACACAACTTAGAATAAACTATTGAAGCCAAGATCTAA
TAAGCTTAAGAAGATGAAGTTAACTCCAACTCCGCTGCTGCTGACTTCAAGAGCAAACTT
GAACACGAAATCCAAGTCTATGAAAGAGAACTTGCTAAGTGGTAATAAACCGTTGCTGCT
TTGACTGCCACCGTTGCTTAAGACCACGAAAACGTTAACAACTGTCACTCCTAAGAAGCT
GCCATCCAAGCTAACCTCGATGCTGCTAATTAAGACTATGCCAATGAAAAGGCTACCTTC
GAACACAAGCAAGCCAACTTACAAGAAGAAATCGAAATCTTCATTGAAGTTATTGCTTAC
TATGACGATAACGTCCAAAATGCCGGTGAAGACTTAAAGGAAAGAGTCGAAGATTATAGT
GATGGTAACTTCGATGATGCCGCCACCTACGAAAATAGATAAGTCCCCAATATTGACTTC
ATTAACTGA



>TTHERM_00527180(gene)
TATTTTCAATCAAAAAGCAAAAACATATTCATTCTGAAAAGAAAAATTAAAAGGCATTGA
GTTTTTGTTTTGCTTTAATTAATAGGGAAAAAAAAAAGGGAGAGGAAAAAACAATCAATT
AAAGTCTTTTTGCAAAGTGATAATAAAAATTAAAAAACGAAAAAAAAATAATAATAATTA
ATATACAAAACATAAAAACTAAAAATTAAAAAGGAAAAAGCATTCATCCAGACAAATGAA
TAAGAAATTATTAGTTGTCCTTTTCGGATTCCTCGCTTTGGCTGCTGCTACCAACCAAAG
TGAAGAAGAAGGTTCTTACACCATCGATCAAGCTGCAAATCTTTTAAATGACTTACTTGC
AGATTCTCAACAAAATTTGAGCGATCTCCAAGCTGCATGGGCCAATAAGGAACCTCTTTT
ACAAGGTGTTATTGCTGGACTTGAAAGCGATCTTGCCAACAAGTAAGCTGAATGCGCTGA
TCTCTAAGGTACCCTTGATGCTGATTAAGCTTCCCTCGATGAAGCTGAAGCATACGTTGC
CTGGTTATAAGACAGAATTGCTGCTAACCATAAGCAAATTGACGACTTACTCAACAGAAG
ATGTCAACAAAACGGTAACTACATTGAAGGTCTTAAGAACGACAAGCTCGCTCTTGCTCT
CTTATAATTCCTTGAAGCCTAAATTCAAAACAAGGAATCCTTCTCTTTCCTCCAAAAGAA
GAACTTCATGAAGAAACTCACCCGTTTCTTGAGCATCTACAAAACTGGTAACTATTAATA
ACTCGCTCTCCTTGAAAAGGAATACGTTAACGCTGATGACTACTCAGTTAATCCCGACTA
CTCTACTGGTGACAGAACTGCTGACGAAATCGGATCTGGTCACATTGATAACGACAAGGG
TGATATCGATGTTGCTGACTTCTAAGAAGGTGAAAGAAAGGGATGGTACTAAGTCAAATA
AGAATTATTAGACCTCTTACACAACTTAGAATAAACTATTGAAGCCAAGATCTAATAAGC
TTAAGAAGATGAAGTTAACTCCAACTCCGCTGCTGCTGACTTCAAGAGCAAACTTGAACA
CGAAATCCAAGTCTATGAAAGAGAACTTGCTAAGTGGTAATAAACCGTTGCTGCTTTGAC
TGCCACCGTTGCTTAAGACCACGAAAACGTTAACAACTGTCACTCCTAAGAAGCTGCCAT
CCAAGCTAACCTCGATGCTGCTAATTAAGACTATGCCAATGAAAAGGCTACCTTCGAACA
CAAGCAAGCCAACTTACAAGAAGAAATCGAAATCTTCATTGAAGTTATTGCTTACTATGA
CGATAACGTCCAAAATGCCGGTGAAGACTTAAAGGAAAGAGTCGAAGATTATAGTGATGG
TAACTTCGATGATGCCGCCACCTACGAAAATAGATAAGTCCCCAATATTGACTTCATTAA
CTGAAAAATGATGTGATTTATGGTGATTGCTTGCAACTATGATTAAATAGTTGCAACACC
CAAAAATATTACTATCGAATAAAACGATTTATTAAATATAGATACTTAAATTCTCTTCCT
CAATTCATTTGTCTTTGTGAACAAATAATTGATTACTGTATGTTCTATGTGATTGGAAGT
TATCATTTTTTATTGACCAAATCTTACTTTTATTATTTA



>TTHERM_00527180(protein)
MNKKLLVVLFGFLALAAATNQSEEEGSYTIDQAANLLNDLLADSQQNLSDLQAAWANKEP
LLQGVIAGLESDLANKQAECADLQGTLDADQASLDEAEAYVAWLQDRIAANHKQIDDLLN
RRCQQNGNYIEGLKNDKLALALLQFLEAQIQNKESFSFLQKKNFMKKLTRFLSIYKTGNY
QQLALLEKEYVNADDYSVNPDYSTGDRTADEIGSGHIDNDKGDIDVADFQEGERKGWYQV
KQELLDLLHNLEQTIEAKIQQAQEDEVNSNSAAADFKSKLEHEIQVYERELAKWQQTVAA
LTATVAQDHENVNNCHSQEAAIQANLDAANQDYANEKATFEHKQANLQEEIEIFIEVIAY
YDDNVQNAGEDLKERVEDYSDGNFDDAATYENRQVPNIDFIN