Identifiers and Description

Gene Model Identifier

TTHERM_00529620

Standard Name

XPB1 (homolog of Xeroderma Pigmentosum type B protein 1)

Aliases

PreTt04631 | 67.m00146 | 3684.m00016

Description

DNA repair helicase Rad25; DNA repair helicase rad25 family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• DNA binding (IEA) | GO:0003677
• helicase activity (IEA) | GO:0004386
• hydrolase activity (IEA) | GO:0016787
• nucleic acid binding (IEA) | GO:0003676

Domains

• ( PF00176 ) SNF2-related domain
• ( PF00270 ) DEAD/DEAH box helicase
• ( PF00271 ) Helicase conserved C-terminal domain
• ( PF04851 ) Type III restriction enzyme, res subunit
• ( TIGR00603 ) DNA repair helicase rad25

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_13686.1	9.997093137033517e-262
	Description: DNA repair helicase rad25 family protein (831 aa)
DictyBase	DDB_G0278729	2.0005528695435914e-146
	Description: repB on chromosome: 3 position 1389108 to 1391685
Oxytricha	Contig5586.0.g36	4.9990774786573115e-144
	Description: Helicase conserved C-terminal domain
WormBase	WBGene00013441	7.998494937295598e-144
	Description: status:Partially_confirmed UniProt:Q95PZ4 protein_id:CAC70144.1
WormBase	WBGene00018737	7.998494937295598e-144
	Description: status:Confirmed UniProt:Q20697 protein_id:CCD68828.1
SGD	YIL143C	3.0004885828297914e-109
	Description: SSL2 Component of the holoenzyme form of RNA polymerase transcription factor TFIIH, has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA; involved in DNA repair; homolog of human ERCC3
Stentor Coeruleus	SteCoe_9056	8.628801156620959e-60
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:23884606: Gao S, Xiong J, Zhang C, Berquist BR, Yang R, Zhao M, Molascon AJ, Kwiatkowski SY, Yuan D, Qin Z, Wen J, Kapler GM, Andrews PC, Miao W, Liu Y (2013) Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & development 27(15):1662-79

Sequences

>TTHERM_00529620(coding)
ATGGCTGATAAAAAGGTTAATCCAAAATCTAGAGAATAAAGTAAAAGATTAAAGTCAAAC
TCATAAAAATAAAATTAAAATGGCAAATAATAAAAGAATGAAGAAGGAGATGATGGCTTA
TTTGGCTAAAAATAAGGAAAAGCACAAGTAGAAGGAAATTAATTTCAATAATTTTATGAT
TACTCTACTCTAGAATTAAAAGATGATTACAGAGAAAGACCTATTTTGATATGTCCAGAT
GGAATAATATTTTTAGAAACTTTTAATCCTCTTTACAGGGTTGCCTATTAATTTTTAATT
TCTATTGGAGAGCCTGTGTAAAGACCTCTCTCAATGCATAAATTTACCTTGACTAAGTAT
TCACTTTATACTGCGATGGTTTTATAGTATGAACCTAAAGATATAATTCTGTGTCTCGAA
AAGCTTAGTAAGAACAAAAAAATTCCTAAAGAAGTAGAAAGATATATTACTGAAAATACA
TAAAACTATGGAGCTGCTAGACTATTTTTAGACGACAGTAGTTATTACTTAGATATAGAT
TCTTAGGTATGGACAAGTATAATAGAAAGAAATCCACATATAAAAGACCTAGTTTCACAA
ACATAATTTAACTTTGATAATATTATAAACTAAAATAAAGAATTGAGGGATATTTAAAAA
GATCTGCAAAGCTTCTTTTAAAATATAAAAACAGAAAACAATTAATAATCTTCAAAAAAA
AACTAGAAAATGATTGTTGAAGATGAGCAAGATGATGGAATTCCAGATAAAAAAAATAAA
TTAATGAAAAACGGTGATAGCAGTATTGCTAATTATGATGACGAAGATGAAGAAGATTCT
GATGATGGTGATGATGATTTTGTTTATAATTTCATAATGAATAATAAAACAAAACGGTCT
TTTAAACGTATTTAAATTATTGGAGATCATTTTGAGGTTACTAAAGCTGTTATTAACTGT
AGTGTTCCTCTGATTTAAGAATATGATTTCGAAAACAAAAGCTTCAAATAACTAGAAATT
GAATTAAAGCCAAAAATAAAGGTGAGATATTACCAAGAAAGAGCTTTAAAAAATATATTT
ATATAGAAGAAAGCTCGTTCTGGATTGATAATTCTTCCTTGTGGTGCAGGGAAAACAATT
GTTGGAGTTATTGCTATCGAAAGGATAAAATAAAGTACAGTAATTATTTGTGACTCTGAT
GTTTCTGTGGATTAATGGAGAGATGAACTTGAGAGATGGACTACAATTAATAAAAACAAA
ATAGTTAGATTAACTGGTAGAATAGTGGATGAATGGCCTACTAGAACTACAGATGAGCCT
ATTATTGTGATTACAACATATTATATGCTTGTAAAAAAGCGTGAAGATCTTCCTCCAACT
TAAATTGCTTAAAAGAGCAAAAAGAGATAATACATAGACTCAATGAAGGAAAGAAAATGG
GGAGTTTGTGTGATTGATGAAGTGCATAAATTGCCAGCAAATACTTTTTAAAATGTACTT
AAGCAGTATAAATTCCACTTTAAACTAGGTCTCACTGCTACTCCTTACAGAGAAGATGAA
AAGATTATTAATTTATTTTATATGATAGGACCTAAGTTGTATGAAGAAAATTGGTATGAT
TTAGTTAGTTAAGGATTTTTAGCTAAACCCTACTGTGTAGAAATTAGATGTGAAATGTCG
TAGCTCTGGATGAGCGAGTATAATAAGAAAGATTTAAAGACAGGTAAAAATTACTACAGA
GGGCCATAAAGAGAGTTAATACATACAAGTAACCCAAGAAAATTTAAGACTCTTGAGTAT
CTCATAAAAGTTCATGAAGAAAGAGGAGATAAAATTCTAGTTTTTTGTGATAGACCAATG
ATAATAGATTATTATGGAAATATTTTAAAATATCCAGTTATATATGGAGATGTATCACAA
GATGAGAGAAAGAAAATATTTAATCTATTTAAAGTTTCAAACTAGATAAATACAATATTT
CTTTCCAGAGTTGGAGATACAGCAATAGATTTGCCTCAGGCTAACGTTGGTATCTAAATT
GGAATGCATTTTAAAAGTAGGAGATAAGAAGTTTAGAGGTTAGGTAGAATCATGAGAGCT
AAAGAAAACTATGATGGTTAATATAATGCTTTTTGGTATACATTAGTTTCAAAAGGAACT
GATGAAACTTCCTACTGTTTAGCAAGGCAAAAATGTTTAATAAATTAAGGTTTCAAATAT
GAAATTATTGATGAAAAAGATTTACCATATAGTTAAAATCCTTAAAAGTTTAAGTGGATG
TCTTAATTAGATGAGTCAGATTATCTTTACACATTATTAATGAATTCTGAACAAAATCAG
CAAAATGGCAAAATGTCAAGTGAAGAAGAAAGCTCGAGTGGTGATAGCTCAGGATCAGAT
TCTGAAGAATCAGAAGGACATTTTAATATCACTACAAAAGCTGCAAACCCTTTATAAAAT
CTAGCACTTTACAAAGAAACATAGCTTAATAAATACTGA

>TTHERM_00529620(gene)
ATGGCTGATAAAAAGGTTAATCCAAAATCTAGAGAATAAAGTAAAAGATTAAAGTCAAAC
TCATAAAAATAAAATTAAAATGGCAAATAATAAAAGAATGAAGAAGGAGATGATGGCTTA
TTTGGCTAAAAATAAGGAAAAGCACAAGTAGAAGGAAATTAATTTCAATAATTTTATGAT
TACTCTACTCTAGAATTAAAAGATGATTACAGAGAAAGACCTATTTTGATATGTCCAGAT
GGAATAATATTTTTAGAAACTTTTAATCCTCTTTACAGGGTTGCCTATTAATTTTTAATT
TCTATTGGAGAGCCTGTGTAAAGACCTCTCTCAATGCATAAATTTACCTTGACTAAGTAT
TCACTTTATACTGCGATGGTTTTATAGTATGAACCTAAAGATATAATTCTGTGTCTCGAA
AAGCTTAGTAAGAACAAAAAAATTCCTAAAGAAGTAGAAAGATATATTACTGAAAATACA
TAAAACTATGGAGCTGCTAGACTATTTTTAGACGACAGTAGTTATTACTTAGATATAGAT
TCTTAGGTATGGACAAGTATAATAGAAAGAAATCCACATATAAAAGACCTAGTTTCACAA
ACATAATTTAACTTTGATAATATTATAAACTAAAATAAAGAATTGAGGGATATTTAAAAA
GATCTGCAAAGCTTCTTTTAAAATATAAAAACAGAAAACAATTAATAATCTTCAAAAAAA
AACTAGAAAATGATTGTTGAAGATGAGCAAGATGATGGAATTCCAGATAAAAAAAATAAA
TTAATGAAAAACGGTGATAGCAGTATTGCTAATTATGATGACGAAGATGAAGAAGATTCT
GATGATGGTGATGATGATTTTGTTTATAATTTCATAATGAATAATAAAACAAAACGGTCT
TTTAAACGTATTTAAATTATTGGAGATCATTTTGAGGTTACTAAAGCTGTTATTAACTGT
AGTGTTCCTCTGATTTAAGAATATGATTTCGAAAACAAAAGCTTCAAATAACTAGAAATT
GAATTAAAGCCAAAAATAAAGGTGAGATATTACCAAGAAAGAGCTTTAAAAAATATATTT
ATATAGAAGAAAGCTCGTTCTGGATTGATAATTCTTCCTTGTGGTGCAGGGAAAACAATT
GTTGGAGTTATTGCTATCGAAAGGATAAAATAAAGTACAGTAATTATTTGTGACTCTGAT
GTTTCTGTGGATTAATGGAGAGATGAACTTGAGAGATGGACTACAATTAATAAAAACAAA
ATAGTTAGATTAACTGGTAGAATAGTGGATGAATGGCCTACTAGAACTACAGATGAGCCT
ATTATTGTGATTACAACATATTATATGCTTGTAAAAAAGCGTGAAGATCTTCCTCCAACT
TAAATTGCTTAAAAGAGCAAAAAGAGATAATACATAGACTCAATGAAGGAAAGAAAATGG
GGAGTTTGTGTGATTGATGAAGTGCATAAATTGCCAGCAAATACTTTTTAAAATGTACTT
AAGCAGTATAAATTCCACTTTAAACTAGGTCTCACTGCTACTCCTTACAGAGAAGATGAA
AAGATTATTAATTTATTTTATATGATAGGACCTAAGTTGTATGAAGAAAATTGGTATGAT
TTAGTTAGTTAAGGATTTTTAGCTAAACCCTACTGTGTAGAAATTAGATGTGAAATGTCG
TAGCTCTGGATGAGCGAGTATAATAAGAAAGATTTAAAGACAGGTAAAAATTACTACAGA
GGGCCATAAAGAGAGTTAATACATACAAGTAACCCAAGAAAATTTAAGACTCTTGAGTAT
CTCATAAAAGTTCATGAAGAAAGAGGAGATAAAATTCTAGTTTTTTGTGATAGACCAATG
ATAATAGATTATTATGGAAATATTTTAAAATATCCAGTTATATATGGAGATGTATCACAA
GATGAGAGAAAGAAAATATTTAATCTATTTAAAGTTTCAAACTAGATAAATACAATATTT
CTTTCCAGAGTTGGAGATACAGCAATAGATTTGCCTCAGGCTAACGTTGGTATCTAAATT
GGAATGCATTTTAAAAGTAGGAGATAAGAAGTTTAGAGGTTAGGTAGAATCATGAGAGCT
AAAGAAAACTATGATGGTTAATATAATGCTTTTTGGTATACATTAGTTTCAAAAGGAACT
GATGAAACTTCCTACTGTTTAGCAAGGCAAAAATGTTTAATAAATTAAGGTTTCAAATAT
GAAATTATTGATGAAAAAGATTTACCATATAGTTAAAATCCTTAAAAGTTTAAGTGGATG
TCTTAATTAGATGAGTCAGATTATCTTTACACATTATTAATGAATTCTGAACAAAATCAG
CAAAATGGCAAAATGTCAAGTGAAGAAGAAAGCTCGAGTGGTGATAGCTCAGGATCAGAT
TCTGAAGAATCAGAAGGACATTTTAATATCACTACAAAAGCTGCAAACCCTTTATAAAAT
CTAGCACTTTACAAAGAAACATAGCTTAATAAATACTGA

>TTHERM_00529620(protein)
MADKKVNPKSREQSKRLKSNSQKQNQNGKQQKNEEGDDGLFGQKQGKAQVEGNQFQQFYD
YSTLELKDDYRERPILICPDGIIFLETFNPLYRVAYQFLISIGEPVQRPLSMHKFTLTKY
SLYTAMVLQYEPKDIILCLEKLSKNKKIPKEVERYITENTQNYGAARLFLDDSSYYLDID
SQVWTSIIERNPHIKDLVSQTQFNFDNIINQNKELRDIQKDLQSFFQNIKTENNQQSSKK
NQKMIVEDEQDDGIPDKKNKLMKNGDSSIANYDDEDEEDSDDGDDDFVYNFIMNNKTKRS
FKRIQIIGDHFEVTKAVINCSVPLIQEYDFENKSFKQLEIELKPKIKVRYYQERALKNIF
IQKKARSGLIILPCGAGKTIVGVIAIERIKQSTVIICDSDVSVDQWRDELERWTTINKNK
IVRLTGRIVDEWPTRTTDEPIIVITTYYMLVKKREDLPPTQIAQKSKKRQYIDSMKERKW
GVCVIDEVHKLPANTFQNVLKQYKFHFKLGLTATPYREDEKIINLFYMIGPKLYEENWYD
LVSQGFLAKPYCVEIRCEMSQLWMSEYNKKDLKTGKNYYRGPQRELIHTSNPRKFKTLEY
LIKVHEERGDKILVFCDRPMIIDYYGNILKYPVIYGDVSQDERKKIFNLFKVSNQINTIF
LSRVGDTAIDLPQANVGIQIGMHFKSRRQEVQRLGRIMRAKENYDGQYNAFWYTLVSKGT
DETSYCLARQKCLINQGFKYEIIDEKDLPYSQNPQKFKWMSQLDESDYLYTLLMNSEQNQ
QNGKMSSEEESSSGDSSGSDSEESEGHFNITTKAANPLQNLALYKETQLNKY