Identifiers and Description

Gene Model Identifier

TTHERM_00530520

Standard Name

TTLL15C (Tubulin Tyrosine Ligase-Like )

Aliases

PreTt04715 | 67.m00230 | 3684.m00100

Description

TTLL15C tubulin-tyrosine ligase family protein; Similar to tubulin polyglutamylase; Tubulin-tyrosine ligase/Tubulin polyglutamylase

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

  • aromatic amino acid family biosynthetic process (IEA) | GO:0009073
  • cell wall modification involved in fruit ripening (IEA) | GO:0009829
  • cytoplasmic translational initiation (IEA) | GO:0002183
  • detection of stimulus involved in sensory perception of pain (IEA) | GO:0062149
  • endomitotic cell cycle (IEA) | GO:0007113
  • fibroblast growth factor receptor signaling pathway (IEA) | GO:0008543
  • galactose to glucose-1-phosphate metabolic process (IEA) | GO:0061612
  • generation of mature 3'-end of 5S rRNA generated by RNA polymerase III (IEA) | GO:0002107
  • glycolytic process from glycerol (IEA) | GO:0061613
  • glycolytic process through fructose-6-phosphate (IEA) | GO:0061615
  • heme A biosynthetic process (IEA) | GO:0006784
  • heme biosynthetic process (IEA) | GO:0006783
  • induction of apoptosis by extracellular signals (IEA) | GO:0008624
  • maltoheptaose catabolic process (IEA) | GO:2001123
  • mesangial cell fate commitment (IEA) | GO:0072151
  • mitochondrial membrane organization (IEA) | GO:0007006
  • mitotic cytokinetic cell separation (IEA) | GO:1902409
  • mitotic nuclear division (IEA) | GO:0007067
  • negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902642
  • negative regulation of anterior head development (IEA) | GO:2000743
  • negative regulation of attachment of mitotic spindle microtubules to kinetochore (IEA) | GO:1902424
  • negative regulation of complement-dependent cytotoxicity (IEA) | GO:1903660
  • negative regulation of epithelial cell-cell adhesion involved in epithelium migration (IEA) | GO:1903682
  • negative regulation of fractalkine production (IEA) | GO:0032684
  • negative regulation of hepatocyte growth factor production (IEA) | GO:0032686
  • negative regulation of L-glutamine biosynthetic process (IEA) | GO:0062133
  • negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
  • negative regulation of phytoalexin metabolic process (IEA) | GO:0052321
  • negative regulation of response to drug (IEA) | GO:2001024
  • obsolete histone succinylation (IEA) | GO:0106077
  • obsolete modulation of peptidase activity in other organism involved in symbiotic interaction (IEA) | GO:0052198
  • obsolete negative regulation by organism of symbiont ethylene-mediated defense response (IEA) | GO:0052484
  • obsolete negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity (IEA) | GO:1904218
  • obsolete positive regulation by host of symbiont defense response (IEA) | GO:0052197
  • obsolete positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response (IEA) | GO:0006990
  • obsolete regulation of nucleic acid-templated transcription (IEA) | GO:1903506
  • obsolete reproduction (IEA) | GO:0000003
  • obsolete response to long exposure to lithium ion (IEA) | GO:0043460
  • ommochrome biosynthetic process (IEA) | GO:0006727
  • P granule disassembly (IEA) | GO:1903864
  • phagocytosis (IEA) | GO:0006909
  • plant-type cell wall modification (IEA) | GO:0009827
  • positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
  • positive regulation of forebrain neuron differentiation (IEA) | GO:2000979
  • positive regulation of peroxisome proliferator activated receptor signaling pathway (IEA) | GO:0035360
  • positive regulation of response to water deprivation (IEA) | GO:1902584
  • positive regulation of wound healing, spreading of epidermal cells (IEA) | GO:1903691
  • priming of cellular response to stress (IEA) | GO:0080136
  • pronephric glomerulus morphogenesis (IEA) | GO:0035775
  • propan-2-ol biosynthetic process (IEA) | GO:1902640
  • protein localization to old growing cell tip (IEA) | GO:1903858
  • protein polyglutamylation (ISS) | GO:0018095
  • regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (IEA) | GO:1902646
  • regulation of complement-dependent cytotoxicity (IEA) | GO:1903659
  • regulation of cytokinin dehydrogenase activity (IEA) | GO:1903856
  • regulation of endothelial cell chemotaxis (IEA) | GO:2001026
  • regulation of L-arginine import into cell (IEA) | GO:1902826
  • regulation of microglial cell migration (IEA) | GO:1904139
  • regulation of phosphatidylcholine biosynthetic process (IEA) | GO:2001245
  • regulation of TRAIL production (IEA) | GO:0032679
  • sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway (IEA) | GO:0006992
  • vacuolar acidification (IEA) | GO:0007035

Domains

  • ( PF03133 ) Tubulin-tyrosine ligase family

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:15890843: Janke C, Rogowski K, Wloga D, Regnard C, Kajava AV, Strub JM, Temurak N, van Dijk J, Boucher D, van Dorsselaer A, Suryavanshi S, Gaertig J, Eddé B (2005) Tubulin polyglutamylase enzymes are members of the TTL domain protein family. Science (New York, N.Y.) 308(5729):1758-62

Sequences 

>TTHERM_00530520(coding)
ATGTCTATCTAATTAGCAGCTAAAATTAGTGTGGTTGTTTTAACAGTGGCTTTAGTAATA
GGTGGAGTTAATATTTATTACACATAGAAGCTTAACACTATTTAGCAAGGTTAAAAATTA
AACTAGCAAATTAAATAAGAAGAAGATGATGATGAATATGAAGAGTACACTGTACCTACT
TTAAAAGAAACTATGTTGATTAATGATAGTCTTTTTAACAACACTATTCAAATAATTCAG
AATAAATATAATATCTAAAACTTAACAGAACTTGATGATTTAATCAACTAGTTAGGAAGA
GTTTTCAATGACTTAGAATCTGAAACTCTTTCTTCATACTTTAAGAACTTTGTTAATAAT
CCCCATTAAAATAAAGATATTCAACAAGCATTTTATGGTCTTTACCGTGATGATTTCTAT
TGTATTAAAAGCGATTTATACCATTTCGCTCATGAAGAGGAGTTATACAATAATATTACT
TTATTCTCAGACTGGAATGATTAGTATACTCGTGATGATATTTTTGCAAATTTTTCTAAA
GTTGCTTCTGAAATGTATGGATGGGAACTACCTTCAGACTATTTGAGAAAGGAAAGTTTT
GCTCCAGAAATCAACATTACTTAGTATTATTTTAATCGTCCCAGATTTATGTCCTCTTTT
GTCATGGGTAAGTAGCTTGGTTGTTTATTTTAAGGCATAAACAAAATTCCTAGCAGCGGC
TCATTTACAAGAAAAGAAGGACTTTCTCGCAGCTATAGAAAATTCCTTACTTAAATTGAC
TAGATTAACAGCAACCCTAATATCACAAAAAAATATAGTGACAAGTGCATGAAAGAATTC
AAATTCTTACCCTAAACCTACAATCTTAACAATGTAGATGAATGCAAGAACTTTTTTAAT
TATGTAGAATCTGAAACTTATCAAAAAAAATTCAAAGAAGAAGGTTTCTAATTTATATCT
AAATTAGGAGCAAACGTTCATTAAGGTAAAGGCATCTCAGTAGTCACACCAGCTATTATG
GAAGCTCTTTAAAAGAAATATTAAAATGGTCAATTATGTGGCTCTATTGGTGAGTAAAAT
CCAGAGTTAGTTTAGGAATATATCAATAATCCACTTTTACTTAATGGTGTAAAATTTGAA
GTCCGTATGCATTTTGTTATAGCCTCTCTTAATCCTTTAATCATATATGCTCAAGATAAA
GCTGGTGTTGCCTTCTGTGCTCTTAAGTACAATTCCCATGATTCTTAAATTCAAAGACAT
CTTTGTGTGTATAACATTGCTAGAGAACTGCTTAATCTTTCAGATGAAGAACTCTTCAAG
ATTTCAGGAAAGACTCGTGAATAATTTATGAGTAGCTTTTCTTATTAGCACACCCTAGAA
AGTCTCTAAGAAGAGTTAGAAAAAGAAGGTTCAGTCCCACCTGGATGGGTATTTAATGAC
TTTATCCCTTCTGTTTTCCGTAATTACATTAACACAGTATTATTCTCTCGTTAATATCTC
TCCCCAGATTCTAGATTATATGAGATGTATGCTCCTGACATTCTTGTCAACAAAGATAAC
ATGAAGCCTTACATCCTTGAATATAATACCAATCCACGTATGGTTAACACTAGCTATTTT
GTTCATGGGTGGAATGTTTAAACTATTAAAGATATAGTCCTAATAAACATGGCCCAAGTT
AGATCTAGACACTTTAGAATTAAAACTATAATTGATGAATACGTTAAAGAGTTTTTGCAA
AATAAAAACCCAAATAGATCTGAATACATGAAAAGATTAATTGAAGCAAATAAAAACAAA
ATTGAACCATAGTTCAACGTTGACAAAGAAATAACTTCTTATGTTAAAATCTATGATGAA
TCAACTGAAGAGGATCTATACTACAAGGGCAATCTTATTTTTGATAAAGAATGCTTGCAC
TGA



>TTHERM_00530520(gene)
ATCTAAAAAAAAGAAATATTCATGTCTATCTAATTAGCAGCTAAAATTAGTGTGGTTGTT
TTAACAGTGGCTTTAGTAATAGGTGGAGTTAATATTTATTACACATAGAAGCTTAACACT
ATTTAGCAAGGTTAAAAATTAAACTAGCAAATTAAATAAGAAGAAGATGATGATGAATAT
GAAGAGTACACTGTACCTACTTTAAAAGAAACTATGTTGATTAATGATAGTCTTTTTAAC
AACACTATTCAAATAATTCAGAATAAATATAATATCTAAAACTTAACAGAACTTGATGAT
TTAATCAACTAGTTAGGAAGAGTTTTCAATGACTTAGAATCTGAAACTCTTTCTTCATAC
TTTAAGAACTTTGTTAATAATCCCCATTAAAATAAAGATATTCAACAAGCATTTTATGGT
CTTTACCGTGATGATTTCTATTGTATTAAAAGCGATTTATACCATTTCGCTCATGAAGAG
GAGTTATACAATAATATTACTTTATTCTCAGACTGGAATGATTAGTATACTCGTGATGAT
ATTTTTGCAAATTTTTCTAAAGTTGCTTCTGAAATGTATGGATGGGAACTACCTTCAGAC
TATTTGAGAAAGGAAAGTTTTGCTCCAGAAATCAACATTACTTAGTATTATTTTAATCGT
CCCAGATTTATGTCCTCTTTTGTCATGGGTAAGTAGCTTGGTTGTTTATTTTAAGGCATA
AACAAAATTCCTAGCAGCGGCTCATTTACAAGAAAAGAAGGACTTTCTCGCAGCTATAGA
AAATTCCTTACTTAAATTGACTAGATTAACAGCAACCCTAATATCACAAAAAAATATAGT
GACAAGTGCATGAAAGAATTCAAATTCTTACCCTAAACCTACAATCTTAACAATGTAGAT
GAATGCAAGAACTTTTTTAATTATGTAGAATCTGAAACTTATCAAAAAAAATTCAAAGAA
GAAGGTTTCTAATTTATATCTAAATTAGGAGCAAACGTTCATTAAGGTAAAGGCATCTCA
GTAGTCACACCAGCTATTATGGAAGCTCTTTAAAAGAAATATTAAAATGGTCAATTATGT
GGCTCTATTGGTGAGTAAAATCCAGAGTTAGTTTAGGAATATATCAATAATCCACTTTTA
CTTAATGGTGTAAAATTTGAAGTCCGTATGCATTTTGTTATAGCCTCTCTTAATCCTTTA
ATCATATATGCTCAAGATAAAGCTGGTGTTGCCTTCTGTGCTCTTAAGTACAATTCCCAT
GATTCTTAAATTCAAAGACATCTTTGTGTGTATAACATTGCTAGAGAACTGCTTAATCTT
TCAGATGAAGAACTCTTCAAGATTTCAGGAAAGACTCGTGAATAATTTATGAGTAGCTTT
TCTTATTAGCACACCCTAGAAAGTCTCTAAGAAGAGTTAGAAAAAGAAGGTTCAGTCCCA
CCTGGATGGGTATTTAATGACTTTATCCCTTCTGTTTTCCGTAATTACATTAACACAGTA
TTATTCTCTCGTTAATATCTCTCCCCAGATTCTAGATTATATGAGATGTATGCTCCTGAC
ATTCTTGTCAACAAAGATAACATGAAGCCTTACATCCTTGAATATAATACCAATCCACGT
ATGGTTAACACTAGCTATTTTGTTCATGGGTGGAATGTTTAAACTATTAAAGATATAGTC
CTAATAAACATGGCCCAAGTTAGATCTAGACACTTTAGAATTAAAACTATAATTGATGAA
TACGTTAAAGAGTTTTTGCAAAATAAAAACCCAAATAGATCTGAATACATGAAAAGATTA
ATTGAAGCAAATAAAAACAAAATTGAACCATAGTTCAACGTTGACAAAGAAATAACTTCT
TATGTTAAAATCTATGATGAATCAACTGAAGAGGATCTATACTACAAGGGCAATCTTATT
TTTGATAAAGAATGCTTGCACTGATAGTATTTACAATATAACTATTTATATGCATTAACT
TAATAATAAAGAAGATCAATACAACTTAAAATTAACTTATTGTTTATTTAAAAAATAAAT
TTGATATTTTAATGTTTTCATATATAAACTAAATGCTGGATTTTAGTTATTTGATTTAAA
TGAT



>TTHERM_00530520(protein)
MSIQLAAKISVVVLTVALVIGGVNIYYTQKLNTIQQGQKLNQQIKQEEDDDEYEEYTVPT
LKETMLINDSLFNNTIQIIQNKYNIQNLTELDDLINQLGRVFNDLESETLSSYFKNFVNN
PHQNKDIQQAFYGLYRDDFYCIKSDLYHFAHEEELYNNITLFSDWNDQYTRDDIFANFSK
VASEMYGWELPSDYLRKESFAPEINITQYYFNRPRFMSSFVMGKQLGCLFQGINKIPSSG
SFTRKEGLSRSYRKFLTQIDQINSNPNITKKYSDKCMKEFKFLPQTYNLNNVDECKNFFN
YVESETYQKKFKEEGFQFISKLGANVHQGKGISVVTPAIMEALQKKYQNGQLCGSIGEQN
PELVQEYINNPLLLNGVKFEVRMHFVIASLNPLIIYAQDKAGVAFCALKYNSHDSQIQRH
LCVYNIARELLNLSDEELFKISGKTREQFMSSFSYQHTLESLQEELEKEGSVPPGWVFND
FIPSVFRNYINTVLFSRQYLSPDSRLYEMYAPDILVNKDNMKPYILEYNTNPRMVNTSYF
VHGWNVQTIKDIVLINMAQVRSRHFRIKTIIDEYVKEFLQNKNPNRSEYMKRLIEANKNK
IEPQFNVDKEITSYVKIYDESTEEDLYYKGNLIFDKECLH