Identifiers and Description

Gene Model Identifier

TTHERM_00530659

Standard Name

BIME2 (BIvalents in MEiosis 2)

Aliases

3684.m00838

Description

BIME2 Required for wild-type frequency of meiotic bivalent formation; SNF2-like, N-terminal domain superfamily

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• micronucleus (IDA) | GO:0031040

Biological Process

• chromosome organization involved in meiotic cell cycle (IMP) | GO:0070192

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No.	Gene Name(s)	Paragraph Text
2322	BIME2	Bime2 protein is distantly related to budding yeast Rdh54/Tid1 and the vertebrate Rad54B helicases. In the bime2 deletion mutant, meiotic crossovers are reduced to an estimated 18% of the wild-type number.

Associated Literature

1. Ref:28803330: Shodhan A, Novatchkova M, Loidl J (2017) BIME2, a novel gene required for interhomolog meiotic recombination in the protist model organism Tetrahymena. Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 25(3-4):291-298

Sequences

>TTHERM_00530659(coding)
ATGGCAATTCAACCAAAGGCAAAGTTTTATTTAATAGGAAATAACTAATTTTTGTTGTAA
AGCCAATATCCAATAATACAATAAAAACTAGTTAGCTTATTGTAAAATTTAGGAATCAAC
ATAAAAAATGAAGAGAGTTTTACATAAAAAATACTGTTAAGCAATGAAGATAGAAAAAAA
ATATTGAAAAATGAAGAAATTTAAAAGCTGATCAAAATCAAAGACATCCCAAAGTTTTTA
AAATAAATTATATCTCTACCCAAGTATTAAGTAGACTAGACTCAAATTCAAAAAAAAATT
AAATAACTAAGTGATGTTAAACCTTCTAAGTATTTTGTTTAGTTTTTTATTGATTACATA
GAAAAGCAAGGTAAGATTCTTTTCCTAGATGATGAAATATTTCCAAAGGTAGAAACTATA
TCATTTCTAATTAAAATACTTTGTTTAAATTATGAGAAACCCTGCTTGATCGTAACTGAT
AGTTATAAAGTAGATAATTGGAAAATAAAAGTATAAAAATGGATTCCTAACTAAAAAATA
TCAAAAATCTAAAATTAAAACGATACTGTTTAATCATGTCCATTAGTTATCATAGTTAAC
TACGAGCACTTTTAGAATAATTATGAATGTCTGAGTGTTATAAATTTTGAATTTCTAATA
CTTGACATTCATGTTGATTAGATTAAAACAAATAACTATGATAGCTTATGTAAAATAAGA
AGTAATACAAAATCAGTAATTATAATTGAAAATTATGAGAGATTAAATACTATTGAAGAC
TACTGGTTATATCTTGCAATCCTGCATTCAACAATTTTCAAATTTGAAAGATTCAGCAAA
TTATAAAAAAGATATGCAATACTAGATCAAAATTCAGTCTCATATTAAGAATTTTCTTAT
ATTTTATCAGAATTTTTTCAAACAAACAAAAGTAGAGAAAATCATAAAATTGAGAGTCAA
TCTCTTTTTTAAAAATTTAGCATAGAATTAAATCTCAAGTAAAAAAAGTAGGTATAGTTA
ATTTAAAGACAATTCAATGGATGGGAAATATAAGAATTTGCTAATATTGGTTATCATACT
AATGAAGATATTAATACATACTTTTAATATCTAACTAATTTAAAAGAATAACATAAAAAT
ACTCTCTTAAAATATTTAAGTTTATTGAAGAGAAAGACTCTAGTTATAGCAGATGGAGAT
TAAGTATTGTGTAAATTATTCAAAAAGTATAAAAATGTATAATTTATTTCATCAGAATCT
GATCTTAGTATAGTCAGTCTGAAGGAATATGGTTAAATCTTGATTCTAGAAATTGATCAA
AACTATGAGGTAAAAAAAGCATTCATCCAAAGACTTAAGTAAGATGAAATAATTAAAACG
AGAATGATCTTTTTAGAAATTGCAGACACCTTAGACTCTACTTTGATTGATTATTTTATA
TCTTGA

>TTHERM_00530659(gene)
AATTTAATACATTTTATTTCTCACCAAAGATATATCTTTAATTTTTTAACTTAAATTAAA
AAAAGAATTGATTATTTTTAAATTAATAACAATTTTATTTAATTTAATAAAATTCACTTA
ATTCCAGTTAGAATTTTTCATTTTTAAAGCTTTTACTTAGTTTAAATTTTAGTAATTCTT
TTATTTAAAAAATTTAAAAAGGAAATTTATTTTATGGCAATTCAACCAAAGGCAAAGTTT
TATTTAATAGGAAATAACTAATTTTTGTTGTAAAGCCAATATCCAATAATACAATAAAAA
CTAGTTAGCTTATTGTAAAATTTAGGAATCAACATAAAAAATGAAGAGAGTTTTACATAA
AAAATACTGTTAAGCAATGAAGATAGAAAAAAAATATTGAAAAATGAAGAAATTTAAAAG
CTGATCAAAATCAAAGACATCCCAAAGTTTTTAAAATAAATTATATCTCTACCCAAGTAT
TAAGTAGACTAGACTCAAATTCAAAAAAAAATTAAATAACTAAGTGATGTTAAACCTTCT
AAGTATTTTGTTTAGTTTTTTATTGATTACATAGAAAAGCAAGGTAAGATTCTTTTCCTA
GATGATGAAATATTTCCAAAGGTAGAAACTATATCATTTCTAATTAAAATACTTTGTTTA
AATTATGAGAAACCCTGCTTGATCGTAACTGATAGTTATAAAGTAGATAATTGGAAAATA
AAAGTATAAAAATGGATTCCTAACTAAAAAATATCAAAAATCTAAAATTAAAACGATACT
GTTTAATCATGTCCATTAGTTATCATAGTTAACTACGAGCACTTTTAGAATAATTATGAA
TGTCTGAGTGTTATAAATTTTGAATTTCTAATACTTGACATTCATGTTGATTAGATTAAA
ACAAATAACTATGATAGCTTATGTAAAATAAGAAGTAATACAAAATCAGTAATTATAATT
GAAAATTATGAGAGATTAAATACTATTGAAGACTACTGGTTATATCTTGCAATCCTGCAT
TCAACAATTTTCAAATTTGAAAGATTCAGCAAATTATAAAAAAGATATGCAATACTAGAT
CAAAATTCAGTCTCATATTAAGAATTTTCTTATATTTTATCAGAATTTTTTCAAACAAAC
AAAAGTAGAGAAAATCATAAAATTGAGAGTCAATCTCTTTTTTAAAAATTTAGCATAGAA
TTAAATCTCAAGTAAAAAAAGTAGGTATAGTTAATTTAAAGACAATTCAATGGATGGGAA
ATATAAGAATTTGCTAATATTGGTTATCATACTAATGAAGATATTAATACATACTTTTAA
TATCTAACTAATTTAAAAGAATAACATAAAAATACTCTCTTAAAATATTTAAGTTTATTG
AAGAGAAAGACTCTAGTTATAGCAGATGGAGATTAAGTATTGTGTAAATTATTCAAAAAG
TATAAAAATGTATAATTTATTTCATCAGAATCTGATCTTAGTATAGTCAGTCTGAAGGAA
TATGGTTAAATCTTGATTCTAGAAATTGATCAAAACTATGAGGTAAAAAAAGCATTCATC
CAAAGACTTAAGTAAGATGAAATAATTAAAACGAGAATGATCTTTTTAGAAATTGCAGAC
ACCTTAGACTCTACTTTGATTGATTATTTTATATCTTGAATATATGACTAATATATTGTT
TAATTTATTAAACATTACAAAACTTTATAAATCAATTCATAAAAATTAAAATATTAAATT
TTACATGTAGTCAGTAAGATATTCAGTCA

>TTHERM_00530659(protein)
MAIQPKAKFYLIGNNQFLLQSQYPIIQQKLVSLLQNLGINIKNEESFTQKILLSNEDRKK
ILKNEEIQKLIKIKDIPKFLKQIISLPKYQVDQTQIQKKIKQLSDVKPSKYFVQFFIDYI
EKQGKILFLDDEIFPKVETISFLIKILCLNYEKPCLIVTDSYKVDNWKIKVQKWIPNQKI
SKIQNQNDTVQSCPLVIIVNYEHFQNNYECLSVINFEFLILDIHVDQIKTNNYDSLCKIR
SNTKSVIIIENYERLNTIEDYWLYLAILHSTIFKFERFSKLQKRYAILDQNSVSYQEFSY
ILSEFFQTNKSRENHKIESQSLFQKFSIELNLKQKKQVQLIQRQFNGWEIQEFANIGYHT
NEDINTYFQYLTNLKEQHKNTLLKYLSLLKRKTLVIADGDQVLCKLFKKYKNVQFISSES
DLSIVSLKEYGQILILEIDQNYEVKKAFIQRLKQDEIIKTRMIFLEIADTLDSTLIDYFI
S