Identifiers and Description

Gene Model Identifier

TTHERM_00532220

Standard Name

LRS2 (leucyl-tRNA synthetase 2)

Aliases

PreTt19880 | 68.m00169 | 3830.m00534

Description

LRS2 leucyl-tRNA synthetase protein; leucyl-tRNA synthetase family protein; Leucine-tRNA ligase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cellular bud neck septin structure (IEA) | GO:0000399
• connecting hemi-adherens junction (IEA) | GO:0005926
• ionotropic glutamate receptor complex (IEA) | GO:0008328
• mating projection (IEA) | GO:0005937
• obsolete ectoplasm (IEA) | GO:0043265
• obsolete membrane attack complex protein beta2 chain (IEA) | GO:0008008

Molecular Function

• 11-deoxycorticosterone binding (IEA) | GO:1903878
• 17alpha-hydroxyprogesterone binding (IEA) | GO:1903880
• 3-hydroxybutyrate dehydrogenase activity (IEA) | GO:0003858
• 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity (IEA) | GO:0008413
• ABC-type D-xylose transporter activity (IEA) | GO:0015614
• aminotriazole transporter activity (IEA) | GO:0015241
• cycloheximide transmembrane transporter activity (IEA) | GO:0015243
• four-way junction DNA binding (IEA) | GO:0000400
• galactoside 2-alpha-L-fucosyltransferase activity (IEA) | GO:0008107
• lipopolysaccharide heptosyltransferase activity (IEA) | GO:0008920
• NEDD8 conjugating enzyme activity (IEA) | GO:0061654
• obsolete amiloride transmembrane transporter activity (IEA) | GO:0015240
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• phosphatidylserine decarboxylase activity (IEA) | GO:0004609
• phosphoenolpyruvate carboxykinase activity (IEA) | GO:0004611
• prenyltransferase activity (IEA) | GO:0004659
• prephenate dehydrogenase (NADP+) activity (IEA) | GO:0004665
• proteinase activated receptor binding (IEA) | GO:0031871
• sphingomyelin phosphodiesterase activity (IEA) | GO:0004767

Biological Process

• asymmetric protein localization (IEA) | GO:0008105
• basement membrane organization (IEA) | GO:0071711
• cell wall modification involved in fruit ripening (IEA) | GO:0009829
• cellular response to diacyl bacterial lipopeptide (IEA) | GO:0071726
• coenzyme A metabolic process (IEA) | GO:0015936
• galactose to glucose-1-phosphate metabolic process (IEA) | GO:0061612
• glycolytic process from glycerol (IEA) | GO:0061613
• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• heparan sulfate proteoglycan biosynthetic process (IEA) | GO:0015012
• immunoglobulin heavy chain V-D-J recombination (IEA) | GO:0071707
• learning or memory (IEA) | GO:0007611
• maltoheptaose metabolic process (IEA) | GO:2001122
• microtubule cytoskeleton organization involved in mitosis (IEA) | GO:1902850
• mitochondrial RNA surveillance (IEA) | GO:2000827
• multicellular organism development (IEA) | GO:0007275
• negative regulation of atrichoblast fate specification (IEA) | GO:0010060
• negative regulation of autophagosome fusion (IEA) | GO:1902453
• negative regulation of complement-dependent cytotoxicity (IEA) | GO:1903660
• negative regulation of epithelial cell-cell adhesion involved in epithelium migration (IEA) | GO:1903682
• negative regulation of glycoprotein metabolic process (IEA) | GO:1903019
• negative regulation of L-glutamine biosynthetic process (IEA) | GO:0062133
• negative regulation of macrophage derived foam cell differentiation (IEA) | GO:0010745
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• negative regulation of sprouting angiogenesis (IEA) | GO:1903671
• negative regulation of stomatal opening (IEA) | GO:1902457
• neutral lipid metabolic process (IEA) | GO:0006638
• obsolete histone H4-K20 demethylation (IEA) | GO:0035574
• obsolete larval behavior (sensu Insecta) (IEA) | GO:0007627
• obsolete MAPK cascade involved in ascospore formation (IEA) | GO:1903695
• obsolete negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity (IEA) | GO:1903869
• obsolete reproduction (IEA) | GO:0000003
• ommochrome biosynthetic process (IEA) | GO:0006727
• pattern orientation (IEA) | GO:0007633
• phagocytosis (IEA) | GO:0006909
• phagocytosis, engulfment (IEA) | GO:0006911
• plant-type cell wall modification (IEA) | GO:0009827
• positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
• positive regulation of macrophage derived foam cell differentiation (IEA) | GO:0010744
• positive regulation of peroxisome proliferator activated receptor signaling pathway (IEA) | GO:0035360
• positive regulation of response to water deprivation (IEA) | GO:1902584
• positive regulation of siRNA processing (IEA) | GO:1903705
• positive regulation of wound healing, spreading of epidermal cells (IEA) | GO:1903691
• pronuclear fusion (IEA) | GO:0007344
• propan-2-ol biosynthetic process (IEA) | GO:1902640
• protein localization to old growing cell tip (IEA) | GO:1903858
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
• regulation of autophagosome fusion (IEA) | GO:1902452
• regulation of complement-dependent cytotoxicity (IEA) | GO:1903659
• regulation of cytokinin dehydrogenase activity (IEA) | GO:1903856
• regulation of germ cell proliferation (IEA) | GO:1905936
• regulation of glycoprotein metabolic process (IEA) | GO:1903018
• regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity (IEA) | GO:1903868
• regulation of phosphatidylcholine biosynthetic process (IEA) | GO:2001245
• regulation of skeletal muscle contraction by chemo-mechanical energy conversion (IEA) | GO:0014862
• regulation of TRAIL production (IEA) | GO:0032679
• regulation of tumor necrosis factor production (IEA) | GO:0032680
• response to rest involved in regulation of muscle adaptation (IEA) | GO:0014893
• short-term memory (IEA) | GO:0007614
• striated muscle adaptation (IEA) | GO:0014888
• tertiary alcohol biosynthetic process (IEA) | GO:1902645
• U2-type spliceosome conformational change to release U4 and U1 (IEA) | GO:0000396

Domains

• ( PF00133 ) tRNA synthetases class I (I, L, M and V)
• ( PF09334 ) tRNA synthetases class I (M)
• ( PF13603 ) Leucyl-tRNA synthetase, editing domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00532220(coding)
ATGTTAACGTAATCTATTAGAATTTTATCAAAACCGTTTTTAACAAATCAGTTAAGAACT
TAAAATTTATGTTTGAAGTTAAAAAACTACTTTTCACAGTATGAATTCTCATAAATTGAG
TAGAAGTGGCAGTAAAAATGGAATTAAAATATCCAATCTTCTCATAAAAAGATATCTGAT
ACTAATTAAGAAAAATATTATGTATTATCATAATTCCCATATCCAAGTGGAAATCTCCAC
ATGGGACACGCTAGGGTTTATTACATTTCTGACGTTATTTCCAGGTTTGAAAAAATGAAA
GGTAAAAATGTTATTAATCCTATGGGTTGGGATGCTTTTGGATTACCTGCAGAGAACGCT
GCCATATAAAGAAATATTGAACCTTCAGAATGGACCTATAAAAATATTTAACAAATGAAA
GAATAAATGATAAAATTGGGAGTTGTTTTCGATTGGGATTTAGAACTCTTCACATGCAGA
GAAGATTATTACAAGTGGACTTAATGGATTTTTATTTAACTTTTAAAGAATAAACTTGCT
TATAAGAAAGAAGCAGAGGTCAATTGGGATCCAATCGATTAGACAGTTTTAGCTAATGAA
TAAGTCGATGATTAGGGAAGATCGTGGAGAAGTGGAGCTAAGGTAGAAAAAAAAATGTTA
AATTAATGGTTTATTAAAACTACAGAATATGGAAAAGAACTCTTCTAGGATTTAAGTGAT
TTAGAAGGTTGGCCTTAGGCTGTTCAAGAAATGCAGAGAGGCTGGATAGGTTTTAGTGAG
GGAACTCAAATCAAATTTGAATTATTTTCCTAATAATAATAAAAATGTATTGATGAAATT
GAAGTCTACACAACTCGCCCTGATACAATTTATGGAGTTACTTTCTTAGCATTAGCTTAT
GATCACCAACTAGCTACAAAATTCTTAGCAGGATAAAAAGAGGAAGATCTAGCTGATTAT
GAAAAAATGAAAAACGAAATCAAATCTAGAAAGGATTTGGTTGTTAACAAAATTGGTTAT
AAAGTAAAAGATTATTATGCTGTTAACCCTTTGAGTGGCGAATAAGTTCCTATTTACCTT
GTAGACTATGTTTTGAAAGATTACGGGACTGGTGCAGTAATGGGTGTTCCTGCTCATGAT
GACAGAGACCAAGAATTTGCTAAAAAATACTAAATACCAATTAAAGAAGTCATAAAAGAA
GAAACAGACAACTAGTCAACAAAATAAGTTTTAGTCAATAGTGGAAAATTTAGCAATTTA
GAAATTGCAGAAGCTAAGAAATAGATTAACGAATAATTAATTCAAATTGGAAAAGGCCAT
GTAACATCTAATACTAGCATGAGAGATTGGCTAGTATCTAGATAAAGATATTGGGGAGTT
CCTATCCCTGTGATTGAATGTCCTACTTGTGGAGTTTTACCTGTCCCTGAAGATCAACTT
CCTGTTATTTTACCAGAAAAATTAGGAAATCCTGTTTAATTGAAAAATGGAAATCCATTA
GCTCATATTAAAGATTTTGTGGAGTGTAAATGCCATATTTGTGGTAACAACAAGGCAAAA
AGAGAAACTGATACACTTGATACATTTGTTGATTCTAGTTGGTATTTTTTAAGATTTCCA
GACAGCAAAAATTCGCTCTAAATATTTGATAGCAATCTAATTAAATATTGGGCTCCTGTT
GATTTGTATATTGGAGGTATGGAGCATGCTATTTTACATCTTTTGTATGCTCGTTTTATT
CATAAATTTTTGCACAAACAACAATTTGTACCATTACATAAAGAACCATTCAAGTAGTTA
ATTGTCTAAGGTTTGGTTAAAAGTAAAAGCTATAGATTGAAATAAACAGGATAATACCTC
TATCCTTAGGAAGCTTAAAAATACGCTGAAGATGAATTAGACATTAAAATAGAAAAAATG
TCCAAATCCAAAAATAATGGAGTAAATCCGCTCGAAGAAATTGAAAAGTTTGGAGCTGAC
TGTTTAAGAATGACTTTACTCTTTTATGGACCTAATGAAAAGGATATTGCTTGGGATGGC
AACCTTTAAAAAACGCTGTACTCTTATCTCAATAAGGTGTGGAATTTACACTTGAAAATA
CAGTCGGCTTATAAAAATGATGGTGATTTGCTCAAAAAAATGAACAAATAAGAAAAAATT
TCCACTTTCAAAAAAGTGTATGGATATGTCGAAAATATTCAAAATGCATTAGAAAGAAAA
GATCGTTCTTTCCATGTTGCTATTGCTAGATAAATGGAATTGTATAATTTCTTAAGTGAA
TTGCAAGAATAGTCAGGAATCACATAGGAATTTTCTGAAATTTACGAGTATTTAATCAAT
TCCTTGTATCCATTTGCCCCTCACACTATGAGTGAAATAGCCGAAAATCTTTATAAAAAA
GAATATTAATTTGTATGGCCTGATTTATTAGCTATTAAGAATAAGCATTTGAATGAAGAT
ACTATCTCAGTTAAAATTAATGTTAACAATAAATTTAAAGGATAGCTAGAAATTGAATCT
TCATTTATGGATTCATAAAATGACGAACAAATAATTAAAGCAATAAATGAAAGCCTAAAG
CTTAATATAAGCTAATATAAAAACATAATAAAAATTAACAGAAAAAATGCATTTGTAATA
AATGTCATTTAGTGA

>TTHERM_00532220(gene)
CCTTTTTCTTATAAGACTTATTTAATCTAAACATCATTTTGAAAATGTTAACGTAATCTA
TTAGAATTTTATCAAAACCGTTTTTAACAAATCAGTTAAGAACTTAAAATTTATGTTTGA
AGTTAAAAAACTACTTTTCACAGTATGAATTCTCATAAATTGAGTAGAAGTGGCAGTAAA
AATGGAATTAAAATATCCAATCTTCTCATAAAAAGATATCTGATACTAATTAAGAAAAAT
ATTATGTATTATCATAATTCCCATATCCAAGTGGAAATCTCCACATGGGACACGCTAGGG
TTTATTACATTTCTGACGTTATTTCCAGGTTTGAAAAAATGAAAGGTAAAAATGTTATTA
ATCCTATGGGTTGGGATGCTTTTGGATTACCTGCAGAGAACGCTGCCATATAAAGAAATA
TTGAACCTTCAGAATGGACCTATAAAAATATTTAACAAATGAAAGAATAAATGATAAAAT
TGGGAGTTGTTTTCGATTGGGATTTAGAACTCTTCACATGCAGAGAAGATTATTACAAGT
GGACTTAATGGATTTTTATTTAACTTTTAAAGAATAAACTTGCTTATAAGAAAGAAGCAG
AGGTCAATTGGGATCCAATCGATTAGACAGTTTTAGCTAATGAATAAGTCGATGATTAGG
GAAGATCGTGGAGAAGTGGAGCTAAGGTAGAAAAAAAAATGTTAAATTAATGGTTTATTA
AAACTACAGAATATGGAAAAGAACTCTTCTAGGATTTAAGTGATTTAGAAGGTTGGCCTT
AGGCTGTTCAAGAAATGCAGAGAGGCTGGATAGGTTTTAGTGAGGGAACTCAAATCAAAT
TTGAATTATTTTCCTAATAATAATAAAAATGTATTGATGAAATTGAAGTCTACACAACTC
GCCCTGATACAATTTATGGAGTTACTTTCTTAGCATTAGCTTATGATCACCAACTAGCTA
CAAAATTCTTAGCAGGATAAAAAGAGGAAGATCTAGCTGATTATGAAAAAATGAAAAACG
AAATCAAATCTAGAAAGGATTTGGTTGTTAACAAAATTGGTTATAAAGTAAAAGATTATT
ATGCTGTTAACCCTTTGAGTGGCGAATAAGTTCCTATTTACCTTGTAGACTATGTTTTGA
AAGATTACGGGACTGGTGCAGTAATGGGTGTTCCTGCTCATGATGACAGAGACCAAGAAT
TTGCTAAAAAATACTAAATACCAATTAAAGAAGTCATAAAAGAAGAAACAGACAACTAGT
CAACAAAATAAGTTTTAGTCAATAGTGGAAAATTTAGCAATTTAGAAATTGCAGAAGCTA
AGAAATAGATTAACGAATAATTAATTCAAATTGGAAAAGGCCATGTAACATCTAATACTA
GCATGAGAGATTGGCTAGTATCTAGATAAAGATATTGGGGAGTTCCTATCCCTGTGATTG
AATGTCCTACTTGTGGAGTTTTACCTGTCCCTGAAGATCAACTTCCTGTTATTTTACCAG
AAAAATTAGGAAATCCTGTTTAATTGAAAAATGGAAATCCATTAGCTCATATTAAAGATT
TTGTGGAGTGTAAATGCCATATTTGTGGTAACAACAAGGCAAAAAGAGAAACTGATACAC
TTGATACATTTGTTGATTCTAGTTGGTATTTTTTAAGATTTCCAGACAGCAAAAATTCGC
TCTAAATATTTGATAGCAATCTAATTAAATATTGGGCTCCTGTTGATTTGTATATTGGAG
GTATGGAGCATGCTATTTTACATCTTTTGTATGCTCGTTTTATTCATAAATTTTTGCACA
AACAACAATTTGTACCATTACATAAAGAACCATTCAAGTAGTTAATTGTCTAAGGTTTGG
TTAAAAGTAAAAGCTATAGATTGAAATAAACAGGATAATACCTCTATCCTTAGGAAGCTT
AAAAATACGCTGAAGATGAATTAGACATTAAAATAGAAAAAATGTCCAAATCCAAAAATA
ATGGAGTAAATCCGCTCGAAGAAATTGAAAAGTTTGGAGCTGACTGTTTAAGAATGACTT
TACTCTTTTATGGACCTAATGAAAAGGATATTGCTTGGGATGGCAACCTTTAAAAAACGC
TGTACTCTTATCTCAATAAGGTGTGGAATTTACACTTGAAAATACAGTCGGCTTATAAAA
ATGATGGTGATTTGCTCAAAAAAATGAACAAATAAGAAAAAATTTCCACTTTCAAAAAAG
TGTATGGATATGTCGAAAATATTCAAAATGCATTAGAAAGAAAAGATCGTTCTTTCCATG
TTGCTATTGCTAGATAAATGGAATTGTATAATTTCTTAAGTGAATTGCAAGAATAGTCAG
GAATCACATAGGAATTTTCTGAAATTTACGAGTATTTAATCAATTCCTTGTATCCATTTG
CCCCTCACACTATGAGTGAAATAGCCGAAAATCTTTATAAAAAAGAATATTAATTTGTAT
GGCCTGATTTATTAGCTATTAAGAATAAGCATTTGAATGAAGATACTATCTCAGTTAAAA
TTAATGTTAACAATAAATTTAAAGGATAGCTAGAAATTGAATCTTCATTTATGGATTCAT
AAAATGACGAACAAATAATTAAAGCAATAAATGAAAGCCTAAAGCTTAATATAAGCTAAT
ATAAAAACATAATAAAAATTAACAGAAAAAATGCATTTGTAATAAATGTCATTTAGTGAA
AATATTTGTAAATATAAAAATTTGTATGGCTTAACTTAATATTTATTAAAATACTTTTTA
CTTTTTTAAATTGTATTAAAATTAATAAA

>TTHERM_00532220(protein)
MLTQSIRILSKPFLTNQLRTQNLCLKLKNYFSQYEFSQIEQKWQQKWNQNIQSSHKKISD
TNQEKYYVLSQFPYPSGNLHMGHARVYYISDVISRFEKMKGKNVINPMGWDAFGLPAENA
AIQRNIEPSEWTYKNIQQMKEQMIKLGVVFDWDLELFTCREDYYKWTQWIFIQLLKNKLA
YKKEAEVNWDPIDQTVLANEQVDDQGRSWRSGAKVEKKMLNQWFIKTTEYGKELFQDLSD
LEGWPQAVQEMQRGWIGFSEGTQIKFELFSQQQQKCIDEIEVYTTRPDTIYGVTFLALAY
DHQLATKFLAGQKEEDLADYEKMKNEIKSRKDLVVNKIGYKVKDYYAVNPLSGEQVPIYL
VDYVLKDYGTGAVMGVPAHDDRDQEFAKKYQIPIKEVIKEETDNQSTKQVLVNSGKFSNL
EIAEAKKQINEQLIQIGKGHVTSNTSMRDWLVSRQRYWGVPIPVIECPTCGVLPVPEDQL
PVILPEKLGNPVQLKNGNPLAHIKDFVECKCHICGNNKAKRETDTLDTFVDSSWYFLRFP
DSKNSLQIFDSNLIKYWAPVDLYIGGMEHAILHLLYARFIHKFLHKQQFVPLHKEPFKQL
IVQGLVKSKSYRLKQTGQYLYPQEAQKYAEDELDIKIEKMSKSKNNGVNPLEEIEKFGAD
CLRMTLLFYGPNEKDIAWDGNLQKTLYSYLNKVWNLHLKIQSAYKNDGDLLKKMNKQEKI
STFKKVYGYVENIQNALERKDRSFHVAIARQMELYNFLSELQEQSGITQEFSEIYEYLIN
SLYPFAPHTMSEIAENLYKKEYQFVWPDLLAIKNKHLNEDTISVKINVNNKFKGQLEIES
SFMDSQNDEQIIKAINESLKLNISQYKNIIKINRKNAFVINVIQ