Identifiers and Description

Gene Model Identifier

TTHERM_00548030

Standard Name

SMPD1 (SphingoMyelinase PhophoDiesterase 1)

Aliases

PreTt15052 | 71.m00179 | 3729.m00056

Description

SMPD1 endonuclease/exonuclease/phosphatase family protein; Endonuclease/Exonuclease/phosphatase family protein; cleaves sphingomyelin into cermaide and phosphocholine- second messengers for apoptosis

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cytoplasm (IDA) | GO:0005737
• macronucleus (IDA) | GO:0031039

Domains

• ( PF03372 ) endonuclease/exonuclease/phosphatase family
• ( TIGR03395 ) sphingomyelin phosphodiesterase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_17053.1	9.997093137033517e-262
	Description: endonuclease/Exonuclease/phosphatase (498 aa)
Oxytricha	Contig19618.0.g4	4.000010081770683e-74
	Description: Endonuclease/Exonuclease/phosphatase family
DictyBase	DDB_G0288017	1.999534248571833e-46
	Description: DDB_G0288017 on chromosome: 5 position 978356 to 979732
Stentor Coeruleus	SteCoe_2706	1.4251640827409352e-21
	Description: None
WormBase	WBGene00012105	0.000019995566179747357
	Description: Putative neutral sphingomyelinase status:Confirmed UniProt:O45870 protein_id:CAB04885.2

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00548030(coding)
ATGAAGACATAAGATTTTAAATCCAACCAAAAATCTGGCGATATTGAATCACAAATGCCT
AAATAAGGTTAGAAGGAACAAAGATCAAATAAGGAAAATTCACCTGAAAGATCGTAGCAA
AATATTTCAACGAGCTCAAACAATATTGATAAAATAAACAATACTTTAAATAGCTCGAAT
TTTGAAATTGGAGACAGATTGCCAATGCAAAAAATCTAAGTTATAAAATAAAATTCATCA
CCAAAGAACAACGTTATCTCTAATTATTTAAGCTAAGGAATTAGGTCTGTTCGTGTTCTC
ACTTATAACATCTTTCTAAGACCTCCACCAATCAAGAACAATAAAGACGACTACAAAAAT
GAGAGAACTAAGCTTTTTCTCAATTCAATAAGTGACTTTGATATTGTTTGTCTTTAGGAA
TTGTTTGGTTTTCTCAACCAACGCAAACACAAAATTATATTCAATGCTATGAAACAAGGA
TTCTTCTATCATGCAACATCACCTTCTCCTTCCTTTTTTAGCTCCTACTTGGTAGATGGA
GGATTAGTAACAATTTCTAGATTTCCCATCATAGAAAAGTCGTACAGACCTTTTAAATAT
GGAGTCCTCTCAGATAATTTATCATAGAAGGGTGTTCTATACACAAAAATTTAAGCAAAC
GATTCGTATATTCATCTTTTTAACACACATCTTCAAGCTAGTTACGTAGGTGCTGAAAAT
AATGTGAAAGCTACAGTTATCACAAGAGTAGACCAACTTATTTTGATAAAAGACTTCATA
AAAGAATAAGTAAAAAAGCACAGAGAAAAGGAGAGTGATATTATTATGATTTGTGGTGAT
TTCAATGTTAATGCTCGTCCCTAAACTTATCCTATTCATTATTTAAATGATGTTCCTGAT
ATTTAAGAATATATCAGAAAAATAAACCCAAAAGAATTTAGTGAGTATGACATCCTTAGA
TACATTCTATCTGACTTTGAAAGTATAGAATTCATAGATACATTAAGGAGAAAATTTAAA
GGTGAGTCTCCCATTACTTATGCCGATACTTACATTGATAGGGAAACTTAATAAGAACTA
CCAATGGAAGAGGCTCTAACAATAAAAGAGGATTTACTCCAAAAATCATGCTTAGACTAT
ATTATTCAATTGAAAATTCCGATTGAAGCAAAAGAAGTATAAGAAAATAACAACAACAAC
AACAATAACAACGAAAATGAAGAAGATGATATTGAAGAATTCAAAATGAAAAAATCAAAT
GCGCAATCTCAAAGTGGATTTGTTTTTGATTACGAATAAGTTTTCTTAGAAAAATTCTTT
GTAAAAAACTAACCATTTACATAGTTAAGCGATCATTATGGTGTTTACACAACCCTGAGA
TACGTAAATGTAAACTAAAAAAGTAGTTTCCAATTTAAAGAGTCTGTTATATCTTCTTAG
GATAAAAAAAATATAGATAATAAAAATTAGCACAGCTTTAACAATGCAAGTTTGAATGAA
TGA

>TTHERM_00548030(gene)
ATGAAGACATAAGATTTTAAATCCAACCAAAAATCTGGCGATATTGAATCACAAATGCCT
AAATAAGGTTAGAAGGAACAAAGATCAAATAAGGAAAATTCACCTGAAAGATCGTAGCAA
AATATTTGTAAATCCATATTATATTTTTCACTGAAATGACATAGTAAATTTGAGATAACA
TTATTTTTAATCCTTTTTTATTGAAAAAACAAAAAGCAACGAGCTCAAACAATATTGATA
AAATAAACAATACTTTAAATAGCTCGAATTTTGAAATTGGAGACAGATTGCCAATGCAAA
AAATCTAAGTTATAAAATAAAATTCATCACCAAAGAACAACGTTATCTCTAATTATTTAA
GCTAAGGAATTAGGTCTGTTCGTGTTCTCACTTATAACATCTTTCTAAGACCTCCACCAA
TCAAGAACAATAAAGACGACTACAAAAATGAGAGAACTAAGCTTTTTCTCAATTCAATAA
GTGACTTTGATATTGTTTGTCTTTAGGAATTGTTTGGTTTTCTCAACCAACGCAAACACA
AAATTATATTCAATGCTATGAAACAAGGATTCTTCTATCATGCAACATCACCTTCTCCTT
CCTTTTTTAGCTCCTACTTGGTAGATGGAGGATTAGTAACAATTTCTAGATTTCCCATCA
TAGAAAAGTCGTACAGACCTTTTAAATATGGAGTCCTCTCAGATAATTTATCATAGAAGG
GTGTTCTATACACAAAAATTTAAGCAAACGATTCGTATATTCATCTTTTTAACACACATC
TTCAAGCTAGTTACGTAGGTGCTGAAAATAATGTGGTAAGAGACTATATTAAACAATATT
TATACTAACTAATTAATTAAAAGCATACTATAAAATTAATTAATTTTCATTCATATTACA
CTAAAATTGATAAACAAAATATATTTAAGCATCATTTTTCTTTTCCAAAATTATTAGAAA
GCTACAGTTATCACAAGAGTAGACCAACTTATTTTGATAAAAGACTTCATAAAAGAATAA
GTAAAAAAGCACAGAGAAAAGGAGAGTGATATTATTATGATTTGTGGTGATTTCAATGTT
AATGCTCGTCCCTAAACTTATCCTATTCATTATTTAAATGATGTTCCTGATATTTAAGTA
ACAAAATTATAATAAACCTTTCTTACTAGAAACATTACAATGTTTAACCTAAAAATAAAA
GGAATATATCAGAAAAATAAACCCAAAAGAATTTAGTGAGTATGACATCCTTAGATACAT
TCTATCTGACTTTGAAAGTATAGAATTCATAGATACATTAAGGGTAATTCAAAAAATTTA
TTTTCAATTAATCAATTTAATTTGATTTCGATTTAAAAATTTTTTTTTTTAAACTAATTT
TTGATTATATGTAAATTATCAAATAGAGAAAATTTAAAGGTGAGTCTCCCATTACTTATG
CCGATACTTACATTGATAGGGAAACTTAATAAGAACTACCAATGGAAGAGGCTCTAACAA
TAAAAGAGGATTTACTCCAAAAATCATGCTTAGACTATATTATTCAATTGAAAATTCCGA
TTGAAGCAAAAGAAGTATAAGAAAATAACAACAACAACAACAATAACAACGAAAATGAAG
AAGTAAGATAATAAATAATACATTTGCTACTAAATTATAATTATTAGAATGCGACAGTTT
CTTGAATTTTATTTTTATCAAATTAAAATAGGATGATATTGAAGAATTCAAAATGAAAAA
ATCAAATGCGCAATCTCAAAGTGGATTTGTTTTTGATTACGAATAAGTTTTCTTAGAAAA
ATTCTTTGTAAAAAACTAACCATTTACATAGTTAAGCGATCATTATGGTGTTTACACAAC
CCTGAGATACGTAAATGTAAACTAAAAAAGTAGTTTCCAATTTAAAGAGTCTGTTATATC
TTCTTAGGATAAAAAAAATATAGATAATAAAAATTAGCACAGCTTTAACAATGCAAGTTT
GAATGAATGA

>TTHERM_00548030(protein)
MKTQDFKSNQKSGDIESQMPKQGQKEQRSNKENSPERSQQNISTSSNNIDKINNTLNSSN
FEIGDRLPMQKIQVIKQNSSPKNNVISNYLSQGIRSVRVLTYNIFLRPPPIKNNKDDYKN
ERTKLFLNSISDFDIVCLQELFGFLNQRKHKIIFNAMKQGFFYHATSPSPSFFSSYLVDG
GLVTISRFPIIEKSYRPFKYGVLSDNLSQKGVLYTKIQANDSYIHLFNTHLQASYVGAEN
NVKATVITRVDQLILIKDFIKEQVKKHREKESDIIMICGDFNVNARPQTYPIHYLNDVPD
IQEYIRKINPKEFSEYDILRYILSDFESIEFIDTLRRKFKGESPITYADTYIDRETQQEL
PMEEALTIKEDLLQKSCLDYIIQLKIPIEAKEVQENNNNNNNNNENEEDDIEEFKMKKSN
AQSQSGFVFDYEQVFLEKFFVKNQPFTQLSDHYGVYTTLRYVNVNQKSSFQFKESVISSQ
DKKNIDNKNQHSFNNASLNE