Identifiers and Description

Gene Model Identifier

TTHERM_00548130

Standard Name

PPI2 (peptidylprolyl isomerase 2)

Aliases

PreTt15062 | 71.m00189 | 3729.m00066

Description

PPI2 peptidyl-prolyl cis-trans isomerase cyclophilin-type protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• proton-transporting two-sector ATPase complex, catalytic domain (IEA) | GO:0033178

Molecular Function

• hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances (IEA) | GO:0016820
• peptidyl-prolyl cis-trans isomerase activity (IEA) | GO:0003755

Biological Process

• protein folding (IEA) | GO:0006457
• proton motive force-driven ATP synthesis (IEA) | GO:0015986

Domains

• ( PF00006 ) ATP synthase alpha/beta family, nucleotide-binding domain
• ( PF00160 ) Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
• ( PF00254 ) FKBP-type peptidyl-prolyl cis-trans isomerase
• ( PF00515 ) Tetratricopeptide repeat
• ( PF02874 ) ATP synthase alpha/beta family, beta-barrel domain
• ( PF06324 ) Pigment-dispersing hormone (PDH)
• ( PF07719 ) Tetratricopeptide repeat
• ( TIGR00019 ) peptide chain release factor 1
• ( TIGR00962 ) ATP synthase F1, alpha subunit
• ( TIGR01026 ) ATPase FliI/YscN family
• ( TIGR01040 ) V-type ATPase, B subunit
• ( TIGR02552 ) type III secretion low calcium
• ( TIGR03324 ) alternate F1F0 ATPase, F1 subunit

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_17056.1	9.997093137033517e-262
	Description: hypothetical protein (469 aa)
Oxytricha	Contig19730.0.g30	1.999149254372995e-126
	Description: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
WormBase	WBGene00000883	3.001032840497736e-70
	Description: locus:cyn-7 Peptidyl-prolyl cis-trans isomerase 7 status:Confirmed UniProt:P52015 protein_id:CAA21760.1
Tetrahymena borealis	EI9_03489.1	3.001032840497736e-70
	Description: glutathione S-transferase domain-containing protein (203 aa)
Stentor Coeruleus	SteCoe_5770	8.854771883513433e-70
	Description: None
DictyBase	DDB_G0282359	9.997863464222902e-69
	Description: ppiA on chromosome: 3 position 5684660 to 5685426
SGD	YLR216C	7.00308173940364e-57
	Description: CPR6 Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00548130(coding)
ATGACTTAAGAAATTATTAACATTACAGAAGACGGTGGTATCACCAAGCAAATTCTTCAA
TAAGGTGAAGGAGACGAATATCCATAAGCTGGTTAGACTGTTGAAGTTTTATACACTGGA
AAACTTCTTGATGGAACAGAATTTGATTCAAATACTAATAGAGATGATCCTTTTTCTTTC
ACAATTGGCAAAGGTTAGGTTATCAAAGGATGGGATTTAGGTGTTGCTACAATGAAGAGA
GGTGAAAAGGCTGTCCTTACCTGCACAGCTCCTAATGCCTATGGTGAAACTGGAAGTCCC
CCTAGAATTCCTCCTAATGCTACTTTACAATTTGAAGTTGAATTGATTGACTTCCGCGAG
AGAACTAAAACAAAATGGGATTACTCATTAGAAGAAAGAGTTGAAATTGCCAAAAAATAC
AAAGATGAGGGTAATGACGCTTTCAAAAAAGGTGATCTTGAAGAAGCTGATGTTTTATAC
GATTAATGTATTGATTACGTTGATTTTGGTGAAGATGTTAATGGTTCTCTTGAACTTAAG
TTCACTGCTTACCTTAACCAAGCAACAGTTTATAATAAATAAAAAAAATGGGACAAAGCT
ATTAAGAATTGCACTATTGTTATTGAAAAGCAACCTAATAACATCAAGGCTTACTTCAGA
AGAGGTACTGCTAGAATGAATTATGGTTTCTTAGATGAGGCTAAAGCTGATTTCCATAAA
GCACAAGAATTAGATCCTAACAATGCTGAAGTTATCAATTCTTTGAAAGTTCTTGCTTAG
AAGTAAAAAGAAGCCAATGAAAAGCAAAAGAAAATGTGGGGTGGCCTTTTTAAAAATTCA
TATTATGACGACTAAAAATAAACTATTGTAGAATTCTCTGATCCTAGTAATCCTGTTGTT
TTCTTTGATATTCAAATCGGAGAAGAAGAACCTTAGAGAGTTGAATTTGAGCTTTTCAAG
AATATTGCTCCTAAAACTGCTGAAAATTTCCGTGCCCTTTGCACTGGAGAAAAAGGTACT
GGCGTTTCAGGAAAGCCTCTTCATTATAAGGGATCCATATTCCACCGTCTTATTAAAGAT
TTTATGATTTAGGGAGGTGATTTCACTAACTCTAACGGTACTGGAGGTGAATCAATTTAT
GGCGCCAAATTCCCTGACGAAGACTTCAAAGCAAAGCATACTAAGAGAGGTTTACTCTCT
ATGGCTAACAGTGGTCCTAACACAAACGGAAGTTAGTTCTTTATCACCTTTAAAAAAACA
GAATGGCTCGATGGTAAGCACGTAGTTTTTGGTGCTGTAACTAAAAATATCGAATTCCTT
GATAAACTTGAAAACTCTCCTTGCGAAGGCGAAAACCCATCTCCAAGCATTAAAGTTGTT
GACTGTGGTGTCGTTAAAGCTTGA

>TTHERM_00548130(gene)
ATGACTTAAGAAATTATTAACATTACAGAAGACGGTGGTATCACCAAGCAAATTCTTCAA
TAAGGTGAAGGAGACGAATATCCATAAGCTGGTTAGACTGTTGAAGGTAAATAAATCAAT
TTAATTTAAAGAAGAACTTACTTGTTAGTCACTTTCAATCAACACTCAAATCAAAGAAAG
GCATCGTTTTCTAATTAATTTCAAATTTTAAAAAAACAGTTTTATACACTGGAAAACTTC
TTGATGGAACAGAATTTGATTCAAATACTAATAGAGATGATCCTTTTTCTTTCACAATTG
GCAAAGGTTAGGTTATCAAAGGATGGGATTTAGGTAATATTCAAGAATTTGATTCTTAAA
ATCAGAGTCTGCAATAAAATTTATTTAACAAAAAGGTGTTGCTACAATGAAGAGAGGTGA
AAAGGCTGTCCTTACCTGCACAGCTCCTAATGCCTATGGTGAAACTGGAAGTCCCCCTAG
AATTCCTCCTAATGCTACTTTACAATTTGAAGTTGAATTGATTGACTTCCGCGAGAGAAC
TAAAACAAAATGGGATTACTCATTAGAAGAAAGAGTTGAAATTGCCAAAAAATACAAAGA
TGAGGGTAATGACGCTTTCAAAAAAGGTGATCTTGAAGAAGCTGATGTTTTATACGATTA
ATGTATTGATTACGTTGATTTTGGTGAAGATGTTAATGGTTCTCTTGAACTTAAGTTCAC
TGCTTACCTTAACCAAGCAACAGTAAGAATAATTAAATTTACTTTTTAGAAAACAAAAAT
TTAAAAACAGCTGCAAAAAATAAATCAGCAACAATAGAATTATTTTATTTTTAATTAAAT
AGGTTTATAATAAATAAAAAAAATGGGACAAAGCTATTAAGAATTGCACTATTGTTATTG
AAAAGCAACCTAATAACATCAAGGCTTACTTCAGAAGAGGTACTGCTAGAATGAATTATG
GTTTCTTAGATGAGGCTAAAGCTGATTTCCATAAAGCACAAGAATTAGATCCTAACAATG
CTGAAGTTATCAATTCTTTGAAAGTTCTTGCTTAGAAGTAAAAAGAAGCCAATGAAAAGC
AAAAGAAAATGTGGGGTGGCCTTTTTAAAAATTCATATTATGACGACTAAAAATAAACTA
TTGTAGAATTCTCTGATCCTAGTAATCCTGTTGTTTTCTTTGATATTCAAATCGGAGAAG
AAGAACCTTAGAGAGTTGAATTTGAGCTTTTCAAGAATATTGCTCCTAAAACTGCTGAAA
ATTTCCGTGCCCTTTGCACTGGAGAAAAAGGTACTGGCGTTTCAGGAAAGCCTCTTCATT
ATAAGGGATCCATATTCCACCGTCTTATTAAAGATTTTATGATTTAGGGAGGTGATTTCA
CTAACTCTAACGGTACTGGAGGTGAATCAATTTATGGCGCCAAATTCCCTGACGAAGACT
TCAAAGCAAAGCATACTAAGAGAGGTTTACTCTCTATGGCTAACAGTGGTCCTAACACAA
ACGGAAGTTAGTTCTTTATCACCTTTAAAAAAACAGAATGGCTCGATGGTAAGCACGTAG
TTTTTGGTGCTGTAACTAAAAATATCGAATTCCTTGATAAACTTGAAAACTCTCCTTGCG
AAGGCGAAAACCCATCTCCAAGCATTAAAGTTGTTGACTGTGGTGTCGTTAAAGCTTGA

>TTHERM_00548130(protein)
MTQEIINITEDGGITKQILQQGEGDEYPQAGQTVEVLYTGKLLDGTEFDSNTNRDDPFSF
TIGKGQVIKGWDLGVATMKRGEKAVLTCTAPNAYGETGSPPRIPPNATLQFEVELIDFRE
RTKTKWDYSLEERVEIAKKYKDEGNDAFKKGDLEEADVLYDQCIDYVDFGEDVNGSLELK
FTAYLNQATVYNKQKKWDKAIKNCTIVIEKQPNNIKAYFRRGTARMNYGFLDEAKADFHK
AQELDPNNAEVINSLKVLAQKQKEANEKQKKMWGGLFKNSYYDDQKQTIVEFSDPSNPVV
FFDIQIGEEEPQRVEFELFKNIAPKTAENFRALCTGEKGTGVSGKPLHYKGSIFHRLIKD
FMIQGGDFTNSNGTGGESIYGAKFPDEDFKAKHTKRGLLSMANSGPNTNGSQFFITFKKT
EWLDGKHVVFGAVTKNIEFLDKLENSPCEGENPSPSIKVVDCGVVKA