Identifiers and Description

Gene Model Identifier

TTHERM_00554270

Standard Name

MCM2 (DNA replication licensing factor MCM2)

Aliases

PreTt29234 | 72.m00157

Description

MCM2 MCM2/3/5 family protein; Component of the Mcm2-7 complex involved in DNA replication

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• DNA binding (IEA) | GO:0003677

Biological Process

• DNA replication (IEA) | GO:0006260

Domains

• ( PF00004 ) ATPase family associated with various cellular activities (AAA)
• ( PF00493 ) MCM P-loop domain
• ( PF01078 ) Magnesium chelatase, subunit ChlI
• ( PF07726 ) ATPase family associated with various cellular activities (AAA)
• ( PF07728 ) AAA domain (dynein-related subfamily)

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_29507	0
	Description: None
WormBase	WBGene00003154	9.997093137033517e-262
	Description: locus:mcm-2 status:Partially_confirmed UniProt:Q9XXI9 protein_id:CAA19452.1
Tetrahymena borealis	EI9_07326.1	9.997093137033517e-262
	Description: MCM2/3/5 family protein (901 aa)
DictyBase	DDB_G0286623	9.997093137033517e-262
	Description: mcm2 on chromosome: 4 position 4745862 to 4748971
Oxytricha	Contig13625.0.g30	9.997093137033517e-262
	Description: MCM2/3/5 family
SGD	YBL023C	9.997093137033517e-262
	Description: MCM2 Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
WormBase	WBGene00003858	9.997093137033517e-262
	Description: locus:ogt-1 status:Confirmed UniProt:Q2L6Y4 protein_id:CCD61615.1

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00554270(coding)
ATGGCTGGAAGAAGACGTAGAGATATGATTCCTGAAAATGTAGCTGACAACGATTCAGCT
AGCGTTTCTCAAGAAGAGGCTATAGAAGAAAATTAAATTGTAGAAGAAGATGACAAATCT
TTATCTGATGAAGGCGATGGTGATGATTTGCTTGAAAATATTGAAGATGATTACAAAGCT
GTTCCAGAATTGGATTAATACGAAATAGATGGTTTAAATGATGAAGATGACTTTGATGAT
ATTGATGCAGAACAAAGAAGATTAGCTGAAGAAGAAATTGATGAAAGAAACTATCAAAAA
TATGCCAACAAAAGAAGAATTCCAACTGCCTTAAGAGAGTTTGATTTAGGAGAAGAAGAC
GAAGAAGACTTAAATGTTCAACTTCAAAGAAGAAGATAATTTTATGAAGCTCATAATCTT
TATGAATCTGAAGATGATGAACAAATGGAAGAGGAAGAAGAAAATAAAGATGAAAGAGAA
TATGATAAGTATCTTGATAGAGAATAAGCTAGAGGTAAACTTGCAGTTTGGATTAAGGAA
GAGAGCACTGTGCGTTATATTCGTAAGACTTTCAGAAAGTTCCTCAATAAATTCAAAGAT
GGTTCAAATCAACTAGTTTACAAACAAAGAATTCAAGAAATGTGCTCTAAGAACAAAGGA
AGTTTGGAAGTCGACTTTAATCACATTAATTCTAAGCATGAAACTATAGCCATGTGGATT
GTTACAGAACCAGTAATTATTTTACCATATTTGAATGATGTTGCTATGGAAACAGTCAAG
AAACTTTATCCTGATTACGAAGATATTCAACCTGAAATATTTGTTAGAATTGAAAATTAC
ACAATCTTAGATCATATCAGAAAGCTTCGTCATAAAGATCTTGGTTAATTGATTTAAGTT
AGAGCAGTTGTTACTTAGCGCTCTGCTATTTTCTCTTAATTGAAGAAGGTTTATTATGTC
TGTCGCTGTGGTGATAGAAAAGGACCTATCTACTTATCATCAATAGAAAATCACAATCTT
GGTACTTGTCCTGTTTGCTAGTCTAAGGGACCTTTCATTTTGGATACTGAATATACTATC
TATAGAAATTACTAAAGACTCACTATTTAAGAACCACCTGGTAGCGTTCCTCCTGGTAGA
GTTCCTAGATAAAAAGAAGTCATCGTTTTAGGAGATAACATTGATGTTGCTCGTCCTGGT
GATGAAATTGATGTTACTGGTATTTTCGTTCATAGATATGACTATGCTTTAAATGTTAAG
CACGGTTTCCCTGTTTTTTCAACTATGATAGAAGCTAATTATATTAAGCGTGTAAGAGAA
GGTGATTAATCTTCCTTACCTCCTTAATTCATTGATGAAATTAATAAGCTCTCTAAGAGA
AGCAATTTATCTAAATTAATTTGCAATTCCATAGCTCCTTCTATTTATGAACATGATCAT
GTTAAAATGGCTCTTGCTCTTGCTATGTTCGGAGGTGAACACAAAGACATTTAAGGAAAA
CACAAAATCAGAGGTGATATCAACGTTCTCCTTCTTGGTGATCCTGGTGTTGCCAAATCT
CAATTCTTAAAGAGTGTAGAAAAAACTTTCCATAGATGCGTTTATACTACTGGTAAAGGT
GCATCTGCTGTCGGTTTAACTGCATCTGTAAAGAAAGATAGCTAAACAAAAGAATGGACT
CTTTAAGGTGGTGCTTTGGTTCTTGCTGATAAGGGTATTTGCTTAATTGATGAGTTTGAT
AAAATGAATGATCACGATAGAACTTCCATTCACGAAGCTATGGAACAATAAAGTATTTCT
ATTTCAAAGGTAGGTATTGTAGCAAATCTTCAAGCTAGATGTTCAGTTATTGCTGCTGCA
AACCCAGTCAAAGGTAGATATGATTCATCAGCATCTTTTATGGATAACGTTAATCTTACT
GATCCTATCTTATCCCGTTTTGATATCCTTTGCGTTATTAAAGATGAAGTAAACAAAGAT
CTTGATTATAAGCTTGCTGGTTTCGTACTCAACAGTCACATAAAGAATCACCCAATAAGC
CATAAAGAGAAAAAGCATAATCCTGAACTTTACAGCGAACGTCTTTCTAAATCTCTTATT
GAAGAATCTTAGAAGTAAATAGGTGAAATTATTCCTAATGAAACTTTAAGAAACTACATT
ATGTATGCTCGTTAAAAAATACATCCTAAGTTAGCTGACATTAAAAAAGAAAAAATTAAA
AAATTCTATTCTGACTTACGTTAATAATCAACTATTTCTGGAGGTATGACTATTGCAGTC
AGACATATTGAATCAATTATTAGAATGGCAGAAGCCCATGCTAAAATGCATCTCAGAGAA
GTCGTTAGAGATGAAGATATAGATGTTGCTATTAACGTTATGCTTGAAAGTTTTATTTAA
TCATAAAAGTACTCCGTAGCTAAAACAATACGCGATAACTTTAAAGTTTATTTAACAAAA
GCTTCTGATAATAATAAATATCTATTTAATTTACTAAATAAGCTTTAAAAGGAAAGTAAA
AAAGTTTTATAAAATGTTGCAGATGATAAGAAAGATAAAAAGCAAATTGAATAGACAAAT
ATACCAGTTTATCACTTTGAATTTTAGGCTAAAGACTATAAAATTGAAAAGTTCGACGAT
TTCTATAGAAGTGAATTATTCAATAGATACTACATTAAGCAAGGAAACTAAATTATACCT
AAAAACGATTTTTGA

>TTHERM_00554270(gene)
ATGGCTGGAAGAAGACGTAGAGATATGATTCCTGAAAATGTAGCTGACAACGAGTAATTC
TTTTGCCTTTTTTTAAAGACTTTCATTAAATGATTAATTATTAATTTTTTAAATTTAGTT
CAGCTAGCGTTTCTCAAGAAGAGGCTATAGAAGAAAATTAAATTGTAGAAGAAGATGACA
AATCTTTATCTGATGAAGGCGATGGTGATGATTTGCTTGAAAATATTGAAGATGATTACA
AAGCTGTTCCAGAATTGGATTAATACGAAATAGATGGTTTAAATGATGAAGATGACTTTG
ATGATATTGATGCAGAACAAAGAAGATTAGCTGAAGAAGAAATTGATGAAAGAAACTATC
AAAAGTAAGCACAAAAAATAACTATAAAACAGGATAAAAATTATTATTTGAAAACGTAGA
TATGCCAACAAAAGAAGAATTCCAACTGCCTTAAGAGAGTTTGATTTAGGAGAAGAAGAC
GAAGAAGACTTAAATGTTCAACTTCAAAGAAGAAGATAATTTTATGAAGCTCATAATCTT
TATGAATCTGAAGATGATGAACAAATGGAAGAGGAAGAAGAAAATAAAGATGAAAGAGAA
TATGATAAGTATCTTGATAGAGAATAAGCTAGAGGTAAACTTGCAGTTTGGATTAAGGAA
GAGAGCACTGTGCGTTATATTCGTAAGACTTTCAGAAAGTTCCTCAATAAATTCAAAGAT
GGTTCAAGTAAATAAATATTTAATTTATTTTGATTTACTCCAAGAAGCACTATCAAAATT
AAAGCATAAGATTTAGTGAGCAAAGATTAAAAAATGTTTAAAAATAAAAAATCTTTCATA
AAATATAAAAAATAATATTATTTTTCTGCAAATTTAGTTAGATATAATAAATAATATTAA
GGTGTTTGTAATGGAAAAAAATAAAGTTTAGAGAAAATTTTGAATAATCAAAAAATTTGA
TATTAGCAAATAGATATTATTATTTTGATAAATAAATAAATAAAAAGTTAATTTAATTAG
CACATAATTGAATAAATATTAAATATAAATAGATCAACTAGTTTACAAACAAAGAATTCA
AGAAATGTGCTCTAAGAACAAAGGAAGTTTGGAAGTCGACTTTAATCACATTAATTCTAA
GCATGAAACTATAGCCATGTGGATTGTTACAGAACCAGTAATTATTTTACCATATTTGAA
TGATGTTGCTATGGAAACAGTCAAGAAACTTTATCCTGATTACGAAGATATTCAACCTGA
AATATTTGTTAGAATTGAAAATTACACAATCTTAGATCATATCAGAAAGCTTCGTCATAA
AGATCTTGGTTAATTGATTTAAGTTAGAGCAGTTGTTACTTAGCGCTCTGCTATTTTCTC
TTAATTGAAGAAGGTTTATTATGTCTGTCGCTGTGGTGATAGAAAAGGACCTATCTACTT
ATCATCAATAGAAAATCACAATCTTGGTACTTGTCCTGTTTGCTAGTCTAAGGGACCTTT
CATTTTGGATACTGAATATACTATCTATAGAAATTACTAAAGACTCACTATTTAAGAACC
ACCTGGTAGCGTTCCTCCTGGTAGAGTTCCTAGATAAAAAGAAGTCATCGTTTTAGGAGA
TAACATTGATGTTGCTCGTCCTGGTGATGAAATTGATGTTACTGGTATTTTCGTTCATAG
ATATGACTATGCTTTAAATGTTAAGCACGGTTTCCCTGTTTTTTCAACTATGATAGAAGC
TAATTATATTAAGCGTGTAAGAGAAGGTGATTAATCTTCCTTACCTCCTTAATTCATTGA
TGAAATTAATAAGCTCTCTAAGAGAAGCAATTTATCTAAATTAATTTGCAATTCCATAGC
TCCTTCTATTTATGAACATGATCATGTTAAAATGGCTCTTGCTCTTGCTATGTTCGGAGG
TGAACACAAAGACATTTAAGGAAAACACAAAATCAGAGGTGATATCAACGTTCTCCTTCT
TGGTGATCCTGGGTAATTTTTAGTTTTGTTTCAAATATTTTATCAAAAATATGAATTTAT
TTTCTTATCAATTATTTTTGTAATAATAGTGTTGCCAAATCTCAATTCTTAAAGAGTGTA
GAAAAAACTTTCCATAGATGCGTTTATACTACTGGTAAAGGTGCATCTGCTGTCGGTTTA
ACTGCATCTGTAAAGAAAGATAGCTAAACAAAAGAATGGACTCTTTAAGGTGGTGCTTTG
GTTCTTGCTGATAAGGGTATTTGCTTAATTGATGAGTTTGATAAAATGAATGATCACGAT
AGAACTTCCATTCACGAAGCTATGGAACAATAAAGTATTTCTATTTCAAAGGTAGGTATT
GTAGCAAATCTTCAAGCTAGATGTTCAGTTATTGCTGCTGCAAACCCAGTCAAAGGTAGA
TATGATTCATCAGCATCTTTTATGGATAACGTTAATCTTACTGATCCTATCTTATCCCGT
TTTGATATCCTTTGCGTTATTAAAGATGAAGTAAACAAAGATCTTGATTATAAGCTTGCT
GGTTTCGTACTCAACAGTCACATAAAGAATCACCCAATAAGCCATAAAGAGAAAAAGCAT
AATCCTGAACTTTACAGCGAACGTCTTTCTAAATCTCTTATTGAAGAATCTTAGAAGTAA
ATAGGTGAAATTATTCCTAATGAAACTTTAAGAAACTACATTATGTATGCTCGTTAAAAA
ATACATCCTAAGTTAGCTGACATTAAAAAAGAAAAAATTAAAAAATTCTATTCTGACTTA
CGTTAATAATCAACTATTTCTGGAGGTATGACTATTGCAGTCAGACATATTGAATCAATT
ATTAGAATGGCAGAAGGTAATATTTTTATTTTCAATTTTATTATTTTAGCTAAAAAAATT
TTTATTAAAAGCCCATGCTAAAATGCATCTCAGAGAAGTCGTTAGAGATGAAGATATAGA
TGTTGCTATTAACGTTATGCTTGAAAGTTTTATTTAATCATAAAAGTACTCCGTAGCTAA
AACAATACGCGATAACTTTAAAGTTTATTTAACAAAAGCTTCTGATAATAATAAATATCT
ATTTAATTTACTAAATAAGCTTTAAAAGGAAAGTGTAAATAATTATTAAATTAATAAAAT
TATTTTTCAAATCTTATTTTATCTCTTTAATAGAAAAAAGTTTTATAAAATGTTGCAGAT
GATAAGAAAGATAAAAAGCAAATTGAATAGACAAATATACCAGTTTATCACTTTGAATTT
TAGGCTAAAGACTATAAAATTGAAAAGTTCGAGTAAGATTTTTTATTTTACAGATTATTC
AAACGTTTGCCTAATATTTTTATTTTTTAAAAAATAGCGATTTCTATAGAAGTGAATTAT
TCAATAGATACTACATTAAGCAAGGAAACTAAATTATACCTAAAAACGATTTTTGA

>TTHERM_00554270(protein)
MAGRRRRDMIPENVADNDSASVSQEEAIEENQIVEEDDKSLSDEGDGDDLLENIEDDYKA
VPELDQYEIDGLNDEDDFDDIDAEQRRLAEEEIDERNYQKYANKRRIPTALREFDLGEED
EEDLNVQLQRRRQFYEAHNLYESEDDEQMEEEEENKDEREYDKYLDREQARGKLAVWIKE
ESTVRYIRKTFRKFLNKFKDGSNQLVYKQRIQEMCSKNKGSLEVDFNHINSKHETIAMWI
VTEPVIILPYLNDVAMETVKKLYPDYEDIQPEIFVRIENYTILDHIRKLRHKDLGQLIQV
RAVVTQRSAIFSQLKKVYYVCRCGDRKGPIYLSSIENHNLGTCPVCQSKGPFILDTEYTI
YRNYQRLTIQEPPGSVPPGRVPRQKEVIVLGDNIDVARPGDEIDVTGIFVHRYDYALNVK
HGFPVFSTMIEANYIKRVREGDQSSLPPQFIDEINKLSKRSNLSKLICNSIAPSIYEHDH
VKMALALAMFGGEHKDIQGKHKIRGDINVLLLGDPGVAKSQFLKSVEKTFHRCVYTTGKG
ASAVGLTASVKKDSQTKEWTLQGGALVLADKGICLIDEFDKMNDHDRTSIHEAMEQQSIS
ISKVGIVANLQARCSVIAAANPVKGRYDSSASFMDNVNLTDPILSRFDILCVIKDEVNKD
LDYKLAGFVLNSHIKNHPISHKEKKHNPELYSERLSKSLIEESQKQIGEIIPNETLRNYI
MYARQKIHPKLADIKKEKIKKFYSDLRQQSTISGGMTIAVRHIESIIRMAEAHAKMHLRE
VVRDEDIDVAINVMLESFIQSQKYSVAKTIRDNFKVYLTKASDNNKYLFNLLNKLQKESK
KVLQNVADDKKDKKQIEQTNIPVYHFEFQAKDYKIEKFDDFYRSELFNRYYIKQGNQIIP
KNDF