Identifiers and Description

Gene Model Identifier

TTHERM_00554610

Standard Name

UBA4 (UBiquitin-Activating enzyme 4)

Aliases

PreTt29268 | 72.m00191

Description

UBA4 ubiquitin-like modifier-activating enzyme; Ubiquitin-activating enzyme; provides instructions for activating ubiquitin-like proteins for protein degradation; homolog of UBA5 in Mus musculus

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF00899 ) ThiF family
• ( PF05237 ) MoeZ/MoeB domain
• ( TIGR02354 ) thiamine biosynthesis protein ThiF
• ( TIGR02355 ) molybdopterin synthase sulfurylase MoeB
• ( TIGR02356 ) thiazole biosynthesis adenylyltransferase ThiF

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_07308.1	9.997093137033517e-262
	Description: ThiF family protein (384 aa)
Oxytricha	Contig3977.0.g98	6.000794656677251e-128
	Description: ThiF family
DictyBase	DDB_G0293306	2.0004683842646898e-122
	Description: uba5 on chromosome: 6 position 2741328 to 2742563
WormBase	WBGene00020184	9.997006461365152e-115
	Description: locus:uba-5 Ubiquitin-like modifier-activating enzyme 5 status:Confirmed UniProt:P91430 protein_id:CCD67786.1
Stentor Coeruleus	SteCoe_5601	1.0377033238158346e-53
	Description: None
SGD	YDR390C	0.00000000000003999587784428659
	Description: UBA2 Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Aos1p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00554610(coding)
ATGGATAGCGATAAAGAACTACAAAGGCTTTTAGATGAAAGATAAAAGCTAAATGATAAA
ATTAACGAATATGTTAAAGAAAAGTATTAAAAGTATAAAGGTATGAGCGAAGAGGTCAAG
GATGATAACCCATATAGTCGTTTGATGGCATTGAAGAGAATGGGTGTTGTTTAAAATTAC
GAGAAAATTAGAGATTGTTCAGTTTTAGTTGTTGGTGTTGGTGGTGTAGGTTCAGTATTA
GCTGAAATGCTTACTCGTTGTGGCTTAGGCAAATTGATTATCTACGATTATGATAAAGTA
GAGTTAGCAAACATGAATAGATTGTTTTATACTCCTTAATAAGTTGGTTTATCTAAGGTC
GATGCAGCTAAAGGGACTCTTTAATCTATAAATCCTGAAATTACAATCGAAGCTTACAAC
ATGAACATTACCACTAACAGTGGATTTGAGCACTTGTTAGATAGAATAAAGAAAGGAGGT
AAGAATGGCGAAAGAATTAATTTAGTAGTTTCTTGTGTAGATAACTATGCTGCTCGTATG
GCAATTAATACAGGTTGTAACGAACTTGACCAAATATGGTTTGAAAGTGGTGTAAGTGAA
GATGCTATGAGTGCTCATATTTAGATTATGATTCCAGGTGAAACTGCTTGCTTCGCATGT
GCTACACCTCTTGCTGTGGTTGAAAGTAACGAACACACAATAAAAAGAGAAGGCGTTTGT
GCAGCTTCACTTCCTACTACTATGGGTATTACAGCTGGTTTTCTTGCATAAAATGCCTTA
AAATTCCTTCTTGATTTTGGTGACCTTGCTTTTGTTTTAGCTTATAACGCAAAAGCTGAC
TTTTTCACCAACTATATGATTAAGCCAAACTCTGAATGCAAGGAAAACGAATGTAGAAAA
AGACAAGCTGAAAAGGCTGTTAATAAATAAGAAAACATCCTTGAAAGACTTGAATAAAGA
AAGAAGGCTGCCAAGGAAGCCTTCGAAAAGGAAAATAAACCCAGCGAAAACGAGTGGGGA
ATCGAAATAGTTGATGAATCAGGACCACAAAGTGATTCCAATAAAAAAGATGATGATGTA
AAGGAAATTTCAGAATAAGAAATTGAGCAAAATAATTTGGACGATTTGATGGCAAAACTG
TAAAATATGTGA

>TTHERM_00554610(gene)
ATGGATAGCGATAAAGAACTACAAAGGCTTTTAGATGAAAGATAAAAGCTAAATGATAAA
ATTAACGAATATGTTAAAGAAAAGTATTAAAAGTATAAAGGTATGAGCGAAGAGGTCAAG
GATGATAACCCATATAGGTACTTAGTTAGATACATGAATAAATAAATACATAAATCATAT
CATACATAATATAAATTAAAAGATTAAAAATTGAAATATTTTAACAAATAAACTGAGCAA
TTAAATTAATTAAATTGTTAAAATATAAAATTTATAAGTAAACGCATTATAGAAAATAGT
TCATTTTTATTAAGTTTTTAAGCGATTAGAAATATTTCACTTTCTTCTGTTTTTTATAGA
GAGCAATTACTTTTTTATTTGATAGATTTTAATGGATGAGTAATTAAGCAATTATTTAAT
TTATTTAGTCGTTTGATGGCATTGAAGAGAATGGGTGTTGTTTAAAATTACGAGAAAATT
AGAGATTGTTCAGTTTTAGTTGTTGGTGTTGGTGGTGTAGGTTCAGTATTAGCTGAAATG
CTTACTCGTTGTGGCTTAGGCAAATTGATTATCTACGATTATGATAAAGTAGAGTTAGCA
AACATGAATAGGTAAATAAATAAATCAATTTAAAAATTATTAAAAATGCATAAAATTTTG
TTATAGATTTATAAGAATAAGCATAAAAAAGTTAGAATTTATTTCATATACTTATATCAA
TAGATGATAAAGTAAAAATATAAACATAAATACAGAATAAAATCATAATTTTAAATTATG
TTAAGAAATATTTTTTTTGTTTATCTGTAAAATGTTCAAAAAATTAATAAATTATTAGAT
TAGTTTATATTAATTTTTATTTTAAAAGATTGTTTTATACTCCTTAATAAGTTGGTTTAT
CTAAGGTCGATGCAGCTAAAGGGACTCTTTAATCTATAAATCCTGAAATTACAATCGAAG
CTTACAACATGAACATTACCACTAACAGTAATATATTTTCTTTAAGCTTTTAGATTACTA
TCATCATAATTAAAAAACAGTTAAAATATCAAGATCTTAACATAAAGATATTATTTGTTA
GAAAAATTAATATACTAATAAATAGAAATATAAATAATTTATAAAGATTGTGATCAAAAA
TTAAATTCTATCTAACAATGATAATAAATAAATAAATAAATAAATAAATAAAGCAATTTT
TTATGTATTCATTTTAAATTTATTTAAGAGACTAATTGGAAAGCAAATATTTAAATAGTT
TTCATTTAAACATAAAGGTGGATTTGAGCACTTGTTAGATAGAATAAAGAAAGGAGGTAA
GAATGGCGAAAGAATTAATTTAGTAGTTTCTTGTGTAGATAACTATGCTGCTCGTATGGC
AATTAATACAGGTTGTAACGAACTTGACCAAATATGGTAATTATTTTATATTGATTTTGT
TTTAAAAAAAATGGGAAGTTAAATTTATGAATAAAAAAGTTTTATTAATTAAAAAATAAA
TTGATTTAATCAATCAAGTTAGATCATTATAAAAGCAAAAAATATATTAATAGAAACAAT
TTTGATTTTAGAATAAATAAGGTCTGTAAAAATTAAATAGAAAAAAAATTATGTCAAAAA
TAAGAAGAAAAAAAAAAATCTTTATTATTCTTGAAGACAGATTTAAATTTATTAATTTAG
AATAAATAAATAATCTAAGAGTATGCGTCACTCACTTTTAATAATCAACCATTTTAAATT
TTTATAACAATATTATTATGCAATATTGTTTAATTTATTTGGATCGTCTATTATAAATTA
CAATAGATTTTACGTCATACTTTATAATAAAAATTAACCATTTTTTTATTATTTAAGTTT
TTTAAATTTATAATATAATTCTATCTTGTTGATAACTTTTTGGTGCTCCTTAAAAGATTT
TCAAAAATTTGATTCATTTTTTCAAAAATAAAAATTCATCATCTAAAAACCAAAAATTAT
AATAAAAATTTATTCTATAAAATGTAAGAATATTCTATTTAAAATTTCAAAATCAAACCA
ATAAATATTACAACTTTTGTAGTTTTATAATATGATCTAGCACAATAAACAGCTTATTTG
CATTTTTATTGATACAATTTTTAGAATGCATCAATAAAAAGTTTTATTTCCCCTTTTAGA
TTTTCAAAAAAATGTAAAGCTTCAAAGAAAAAAAATATGATTTTTTAACAAGTTATTGTA
ACATGATATTTTATTGCGTAACAAATTAGTATTGAGTCATTTATCAATCAATTTATTTTT
AAAACTGCCTTTACCCCCTCGTTTGTGAATTAATTTATAGGAGAAGATAGCCTTATAATT
TTTGCTTGTAACCTAACTCTAACTTTAAGATATTTTTTATTATGTATTTTTCAGGTTTGA
AAGTGGTGTAAGTGAAGATGCTATGAGTGCTCATATTTAGATTATGATTCCAGGTGAAAC
TGCTTGCTTCGCATGTGCTACACCTCTTGCTGTGGTTGAAAGTAACGAACACACAATAAA
AAGAGAAGGCGTTTGTGCAGCTTCACTTCCTACTACTATGGGTATTACAGCTGGTTTTCT
TGCATAAAATGCCTTAAAATTCCTTCTTGATTTTGGTGACCTTGCTTTTGTTTTAGCTTA
TAACGCAAAAGCTGACTTTTTCACCAACTATATGATTAAGCCAAACTCTGAATGCAAGGA
AAACGAATGTAGAAAAAGACAAGCTGAAAAGGCTGTTAATAAATAAGAAAACATCCTTGA
AAGACTTGAATAAAGAAAGAAGGCTGCCAAGGAAGCCTTCGAAAAGGAAAATAAACCCAG
CGAAAACGAGTGGGGAATCGAAATAGTTGATGAATCAGGACCACAAAGTGATTCCAATAA
AAAAGATGATGATGTAAAGGAAATTTCAGAATAAGAAATTGAGCAAAATAATTTGGACGA
TTTGATGGCAAAACTGTAAAATATGTGA

>TTHERM_00554610(protein)
MDSDKELQRLLDERQKLNDKINEYVKEKYQKYKGMSEEVKDDNPYSRLMALKRMGVVQNY
EKIRDCSVLVVGVGGVGSVLAEMLTRCGLGKLIIYDYDKVELANMNRLFYTPQQVGLSKV
DAAKGTLQSINPEITIEAYNMNITTNSGFEHLLDRIKKGGKNGERINLVVSCVDNYAARM
AINTGCNELDQIWFESGVSEDAMSAHIQIMIPGETACFACATPLAVVESNEHTIKREGVC
AASLPTTMGITAGFLAQNALKFLLDFGDLAFVLAYNAKADFFTNYMIKPNSECKENECRK
RQAEKAVNKQENILERLEQRKKAAKEAFEKENKPSENEWGIEIVDESGPQSDSNKKDDDV
KEISEQEIEQNNLDDLMAKLQNM