Identifiers and Description

Gene Model Identifier

TTHERM_00577080

Standard Name

PGM1 (PhosphoGlucoMutase )

Aliases

PreTt28995 | 77.m00207 | 3812.m02684

Description

PGM1 cytoplasmic phosphoglucomutase; Phosphoglucomutase; carbohydrate metabolism enzyme that catalyzes the conversion of alpha-D-glucose 1-phosphate into alpha-D-glucose 6-phosphate; knock-out mutants have no defects in growth, morphology or exocytosis; Phosphoglucomutase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cytosol (IDA) | GO:0005829

Molecular Function

• phosphoglucomutase activity (IMP) | GO:0004614

Biological Process

• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• ommochrome biosynthetic process (IEA) | GO:0006727
• phagocytosis (IEA) | GO:0006909
• protein localization to old growing cell tip (IEA) | GO:1903858

Domains

• ( PF02878 ) Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
• ( PF02879 ) Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
• ( PF02880 ) Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

• ( SD01607 )
• ( SD01730 )

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:9382866: Chilcoat ND, Turkewitz AP (1997) In vivo analysis of the major exocytosis-sensitive phosphoprotein in Tetrahymena. The Journal of cell biology 139(5):1197-207
2. Ref:8582637: Huvos P (1995) Developmental DNA rearrangements and micronucleus-specific sequences in five species within the Tetrahymena pyriformis species complex. Genetics 141(3):925-36

Sequences

>TTHERM_00577080(coding)
ATGGATACCCATCATACAATTGTTCATAAGGAACCCATCACTGTTTAAGTTGTTCAAACC
AAGCCTTTTGCTGGTTAGAAACCTGGTACTTCTGGACTTCGTAAAAAGGTTAGTGTTGTT
AAGGAGGCTCATTACTTAGAAAATTTCGTAAGCTCAGTCTTTAAAACCATTCCCAGCGAA
GAATTTACAAAGGAAAACATCTTGGTTGTTGGTGGTGATGGCAGATATTTCAACAAAGAA
GCCATCGATATCATCATTAAAATTGCTGCTGCAGAAGGTGTTGATCACATTCACGTCGCT
CATACTGGTTTAATGTCCACTCCTGCTGTCTCTGCTTACGTCAGACATTTGAATCTCGAC
TTGAAGCTTAACTGCATTGGTGCTTTTATCTTAACTGCTTCTCACAATCCTGGTGGTCCA
ACTAACGATTTTGGTATCAAATTCAATGTTAGAAATGGTGGTCCAGCTCTTGAAGACTTC
ACTAACACCATCTACAAGCACACTACTGAAATAACTTCTTACAAGATTGCTCATGGTGAA
ATAAAGTATGATTTACACAAGATATAAGAGTACGTTTTCGAAAATGTAGAAAGAGAATCA
AAGAGACCTAAATTCACTATCAAGGTTGTAGACTCAACTGAAAATTACATTAATTTAATG
AAAACCCTCTTCGACTTTGATAAATTGAAGAAACTTTTCTAAAGAAAGGACTTCTAGTTC
CGTTTCGATGGCATGCATGGTGTCGCTGGACCTTATGCTCATAAAATCTTCCATGAAATT
CTTGGTGCTCACACTGATAATTTGATTAACTGTAACCCTAAAGAAGACTTTGGTGGTGGT
CATCCCGATCCTAACCTCACCTATGCTGAGCATCTTGTTAAAATTATGGATGTCCACAAC
ATGATTAATACTATTGCAGAAAGAATTCCCAATTTTGGTGCTGCATGTGATGGTGATGCT
GATAGAAATATGATCTTAGGAAGACGTTTCTTTGTTACTCCTAGTGATTCTGTTGCTGTC
TTGGCTGCTAATGCTAGCTCCGTATTTGGTAAGAATGGACATCTTTTAGGTGTTGCCCGT
TCCATGCCTACATCTGGTGCTCTTGATAAGGTAGCTGCCAAGCTTGGAATCAAAAACCTT
TATGAAACTCCCACTGGATGGAAGTTCTTTGGTAACTTGATGGATGCTGGAAAAATTAAT
ATTTGCGGAGAAGAAAGCTTTGGTACTGGTTCTAATCACATTAGAGAAAAGGATGGTATT
TGGGCTATTTTAGCATGGTTGAGCGTTATTGCTGACAGAAACGTAGACAAAACTTAAGAA
GGTCATCTTATCGGAGTTTAATAAATAGTCGAAGAATTCTGGAAGACTTATGGAAGAAAC
TACTATTCTAGATACGATTATGAAGGAGTTGATGCCGATGCTGCCAATAAAGTTATGGCT
CATCTTGAAACCCAATTCAAGCACTTCGAAGAATTATAGAAAGGTAATGTTGCTGATATT
TTCAACTATACTGATCCTGTTGATGGATCTGTTAGCAAGAACTAAGGTATTAGATTTATC
TACGCCGATGGTTCTAGAATCATTTTCAGATTAAGTGGTACTGGTTCTGAAGGAGCTACA
ATTAGAATTTACTTTGAAAAGTATGAAGCTACTGATATTGATCAAAGAACTGATTTAGCC
TTAGAAGAAATAATAAATTTAGGTCTCTAACTTTCTAAGATTTCTGAATTCACTGGAAGA
AATGAACCTACTGTTATCACATGA

>TTHERM_00577080(gene)
TTAAAAATTTTTATTTCTATCAAACAAAAACGTAGAGTATTCCAAAGATACTCCTATAAT
TAATTAATAAATCAAAAATTAAAAATTTAATAGATCACTAAAAAATATACCAAATGGATA
CCCATCATACAATTGTTCATAAGGAACCCATCACTGTTTAAGTTGTTCAAACCAAGCCTT
TTGCTGGTTAGAAACCTGGTACTTCTGGACTTCGTAAAAAGGTTAGTGTTGTTAAGGAGG
CTCATTACTTAGAAAATTTCGTAAGCTCAGTCTTTAAAACCATTCCCAGCGAAGAATTTA
CAAAGGAAAACATCTTGGTTGTTGGTGGTGATGGCAGATATTTCAACAAAGAAGCCATCG
ATATCATCATTAAAATTGCTGCTGCAGAAGGTGTTGATCACATTCACGTCGCTCATACTG
GTTTAATGTCCACTCCTGCTGTCTCTGCTTACGTCAGACATTTGAATCTCGACTTGAAGC
TTAACTGCATTGGTGCTTTTATCTTAACTGCTTCTCACAATCCTGGTGGTCCAACTAACG
ATTTTGGTATCAAATTCAATGTTAGAAATGGTGGTCCAGCTCTTGAAGACTTCACTAACA
CCATCTACAAGCACACTACTGAAATAACTTCTTACAAGATTGCTCATGGTGAAATAAAGT
ATGATTTACACAAGATATAAGAGTACGTTTTCGAAAATGTAGAAAGAGAATCAAAGAGAC
CTAAATTCACTATCAAGGTTGTAGACTCAACTGAAAATTACATTAATTTAATGAAAACCC
TCTTCGACTTTGATAAATTGAAGAAACTTTTCTAAAGAAAGGACTTCTAGTTCCGTTTCG
ATGGCATGCATGGTGTCGCTGGACCTTATGCTCATAAAATCTTCCATGAAATTCTTGGTG
CTCACACTGATAATTTGATTAACTGTAACCCTAAAGAAGACTTTGGTGGTGGTCATCCCG
ATCCTAACCTCACCTATGCTGAGCATCTTGTTAAAATTATGGATGTCCACAACATGATTA
ATACTATTGCAGAAAGAATTCCCAATTTTGGTGCTGCATGTGATGGTGATGCTGATAGAA
ATATGATCTTAGGAAGACGTTTCTTTGTTACTCCTAGTGATTCTGTTGCTGTCTTGGCTG
CTAATGCTAGCTCCGTATTTGGTAAGAATGGACATCTTTTAGGTGTTGCCCGTTCCATGC
CTACATCTGGTGCTCTTGATAAGGTAGCTGCCAAGCTTGGAATCAAAAACCTTTATGAAA
CTCCCACTGGATGGAAGTTCTTTGGTAACTTGATGGATGCTGGAAAAATTAATATTTGCG
GAGAAGAAAGCTTTGGTACTGGTTCTAATCACATTAGAGAAAAGGATGGTATTTGGGCTA
TTTTAGCATGGTTGAGCGTTATTGCTGACAGAAACGTAGACAAAACTTAAGAAGGTCATC
TTATCGGAGTTTAATAAATAGTCGAAGAATTCTGGAAGACTTATGGAAGAAACTACTATT
CTAGATACGATTATGAAGGAGTTGATGCCGATGCTGCCAATAAAGTTATGGCTCATCTTG
AAACCCAATTCAAGCACTTCGAAGAATTATAGAAAGGTAATGTTGCTGATATTTTCAACT
ATACTGATCCTGTTGATGGATCTGTTAGCAAGAACTAAGGTATTAGATTTATCTACGCCG
ATGGTTCTAGAATCATTTTCAGATTAAGTGGTACTGGTTCTGAAGGAGCTACAATTAGAA
TTTACTTTGAAAAGTATGAAGCTACTGATATTGATCAAAGAACTGATTTAGCCTTAGAAG
AAATAATAAATTTAGGTCTCTAACTTTCTAAGATTTCTGAATTCACTGGAAGAAATGAAC
CTACTGTTATCACATGATTGATTTTCCAATAATTAAATTGATTGAATATTTATTAAATAT
TTTAAATATATTTTTGCATATTGAGTAATATCCATTTTAAAGATTTACTAATAATTT

>TTHERM_00577080(protein)
MDTHHTIVHKEPITVQVVQTKPFAGQKPGTSGLRKKVSVVKEAHYLENFVSSVFKTIPSE
EFTKENILVVGGDGRYFNKEAIDIIIKIAAAEGVDHIHVAHTGLMSTPAVSAYVRHLNLD
LKLNCIGAFILTASHNPGGPTNDFGIKFNVRNGGPALEDFTNTIYKHTTEITSYKIAHGE
IKYDLHKIQEYVFENVERESKRPKFTIKVVDSTENYINLMKTLFDFDKLKKLFQRKDFQF
RFDGMHGVAGPYAHKIFHEILGAHTDNLINCNPKEDFGGGHPDPNLTYAEHLVKIMDVHN
MINTIAERIPNFGAACDGDADRNMILGRRFFVTPSDSVAVLAANASSVFGKNGHLLGVAR
SMPTSGALDKVAAKLGIKNLYETPTGWKFFGNLMDAGKINICGEESFGTGSNHIREKDGI
WAILAWLSVIADRNVDKTQEGHLIGVQQIVEEFWKTYGRNYYSRYDYEGVDADAANKVMA
HLETQFKHFEELQKGNVADIFNYTDPVDGSVSKNQGIRFIYADGSRIIFRLSGTGSEGAT
IRIYFEKYEATDIDQRTDLALEEIINLGLQLSKISEFTGRNEPTVIT