Identifiers and Description

Gene Model Identifier

TTHERM_00614720

Standard Name

RAB5C (Rab V family protein; small monomeric GTPase that regulates membrane fusion and fission events)

Aliases

PreTt19120 | 85.m00113 | 3725.m00006

Description

RAB5C Rab-family small GTPase; small GTP-binding protein domain containing protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• intracellular anatomical structure (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase-mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00009 ) Elongation factor Tu GTP binding domain
• ( PF00025 ) ADP-ribosylation factor family
• ( PF00071 ) Ras family
• ( PF01926 ) 50S ribosome-binding GTPase
• ( PF08477 ) Ras of Complex, Roc, domain of DAPkinase
• ( TIGR00073 ) hydrogenase accessory protein HypB
• ( TIGR00231 ) small GTP-binding protein domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_21122.1	5.001897638882051e-133
	Description: small GTP-binding protein domain-containing protein (205 aa)
Oxytricha	Contig16543.0.g107	1.0002546821282671e-50
	Description: Ras family
SGD	YKR014C	2.99915080840225e-45
	Description: YPT52 Rab family GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis
DictyBase	DDB_G0271984	9.001612426253082e-40
	Description: rab5A on chromosome: 2 position 1113320 to 1114208
WormBase	WBGene00004268	4.001416569413617e-37
	Description: locus:rab-5 status:Partially_confirmed UniProt:P91857 protein_id:CAB04205.1
Tetrahymena borealis	EI9_06769.1	4.001416569413617e-37
	Description: hypothetical protein (1810 aa)
Stentor Coeruleus	SteCoe_36517	7.095474162284704e-23
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00614720(coding)
ATGGGAAACGTATGCGGAGGATCTTCACAATCATCATCTAGTAGTAAAAGCTAGAGAGCA
TTAAGATTAAGGGATGAAAAAAAACCAGCATAATAGGCAAAAGTAGTATTATTAGGAAAT
ATAGCAGTAGGAAAAACTGCAATCACTCAAAGATTTAAATAAGGAATATTTGATCCAGCC
CACCAAGCAACATTAGGAGCAGCATACATAGAAAAAAATATTACATTATAAGATAATTCC
GTTTTGTCTTTGCATATTTGGGATACAGCAGGAGATGAAAGATATCGCTCAATCCTTTCC
ATGTAAATTTTAATTCTCAATATTTTGTGGAAGCCAAAGTTTTATAGAGATTCTTAGGCA
GCCATTTTAGTTTATGATGTGACTGATGCAGATAGTTTCAATAGTTTGTAATTATGGATA
AACGAGCTTGAAGATAAAGCAAAAACAGAAGGCATGATTATAGCTCTAGTTGGTAATAAA
ATAGATTCACCTTATGAAATGGTAAAAGTTTCAACATAGAAGGCAGAGCAATTTGCTAGA
GAGAAAAACTTCTTGTTTACTGAGTGTTCAGCCAAAACAGGAGAAGGAATAGATAGAATA
TTTAATATGATAGTTGAAGAATTAATAAAAAAGAAAAAATCAGAGCATAACTGA

>TTHERM_00614720(gene)
ATGGGAAACGTATGCGGAGGATCTTCACAATCATCATCTAGTAGTAAAAGCTAGAGAGCA
TTAAGATTAAGGGATGAAAAAAAACCAGCATAATAGGCAAAAGTAGTATTATTAGGAAAT
ATAGCAGTAGGTATTCAATTAAAATAGCAACTAGAATTAATTTTAAACAGCTATTTTAGC
AGTTTTAGTTTGAAACATTTTTTATAGAATATATTTAATCTAATATAAAGGAAAAACTGC
AATCACTCAAAGATTTAAATAAGGAATATTTGATCCAGCCCACCAAGCAACATTAGGAGC
AGCATACATAGAAAAAAATATTACATTATAAGATAATTCCGTTTTGTCTTTGCATATTTG
GGATACAGCAGGAGATGAAAGATATCGTAAATTATTAATCATTTTTAACTTTTACTTAAA
CCAGAACAAAAAAATTGTTGAACTTTATCATTTTACACGTTTTTATCGGTTTTATTGATT
TGTTTAATAAATTTTCAAAAATATATGTAAAATATTAACAATATTTTCTAAAAAAAAAAT
AGGCTCAATCCTTTCCATGTAAATTTTAATTCTCAATATTTTGTGGAAGCCAAAGTAAGT
AAAAATACGAAATGGGCTTTGATTATTTTAAAAGAGCGAGAAAGAGATTTTATGTAATAA
TAAAAATAATTAAATTTATAGGTTTTATAGAGATTCTTAGGCAGCCATTTTAGTTTATGA
TGTGACTGATGCAGATAGTTTCAATAGTTTGTAATTATGGATAAACGAGCTTGAAGATAA
AGCAAAAACAGAAGGCATGATTATAGCTCTAGTTGGTAATAAAATAGATTCACCTTATGA
AATGGTAAAAGTTTCAACATAGAAGGCAGAGCAATTTGCTAGAGAGAAAAACTTCTTGTT
TACTGAGTGTTCAGCCAAAACAGGAGAAGGAATAGATAGAATATTTAATATGATAGTTGA
AGAATTAATAAAAAAGAAAAAATCAGAGCATAACTGA

>TTHERM_00614720(protein)
MGNVCGGSSQSSSSSKSQRALRLRDEKKPAQQAKVVLLGNIAVGKTAITQRFKQGIFDPA
HQATLGAAYIEKNITLQDNSVLSLHIWDTAGDERYRSILSMQILILNILWKPKFYRDSQA
AILVYDVTDADSFNSLQLWINELEDKAKTEGMIIALVGNKIDSPYEMVKVSTQKAEQFAR
EKNFLFTECSAKTGEGIDRIFNMIVEELIKKKKSEHN