Identifiers and Description

Gene Model Identifier

TTHERM_00614820

Standard Name

POL12 (DNA polymerase alpha subunit B)

Aliases

PreTt19130 | 85.m00123 | 3725.m00016

Description

DNA polymerase epsilon subunit B; Homolog of Saccharomyces POL12- B subunit of DNA polymerase alpha-primase complex.

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• DNA binding (IEA) | GO:0003677
• DNA-directed DNA polymerase activity (IEA) | GO:0003887

Biological Process

• DNA replication (IEA) | GO:0006260

Domains

• ( PF04042 ) DNA polymerase alpha/epsilon subunit B

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_18325.1	9.997093137033517e-262
	Description: hypothetical protein (597 aa)
Oxytricha	Contig11781.0.0.g16	0.00000000000004998767099442072
	Description: DNA polymerase alpha/epsilon subunit B
SGD	YBL035C	0.00000000000006002591555650462
	Description: POL12 B subunit of DNA polymerase alpha-primase complex, required for initiation of DNA replication during mitotic and premeiotic DNA synthesis; also functions in telomere capping and length regulation
DictyBase	DDB_G0282731	0.00000000000040012475857291343
	Description: polA2 on chromosome: 3 position 6220731 to 6222999
WormBase	WBGene00001002	0.0000000000008001317446409227
	Description: locus:div-1 DNA polymerase alpha subunit B status:Partially_confirmed UniProt:Q21625 protein_id:CAA83467.2
Tetrahymena borealis	EI9_19432.1	0.0000000000008001317446409227
	Description: hypothetical protein (691 aa)

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00614820(coding)
ATGGAAGAATTTGAAAAAATATTAGAAGAAATTGATTCTGCTAATTTAAGCCAAAATGCA
GTTTAATAATTGAAATAGTTAATTATTAGCAATGGAATATTAGATGATGAGTAATTAATG
GAAAAGTGGCTCTTTTAATTGGAGGCAATCATTTACAATAGCAAGTAAAAGTTTCTTGAA
GCTTAACTGATGGATTTTAAGAAGAATGTGCTTAATTAGGACATCAAAAAACCTCAAAAT
GACAATTTTAAAAAAATAAAGGAATCTGAAGTTTAAAAAAATATAGACATTATTAAAGGT
GATGCAGATTTATTTACTAAAGCTTCTTCAGCCAAAAAACAGACATCTACTTAATAAGCA
AATAATGCAGCAATTGATTGCGAAGAATAATTGCGTTAGTAGTTAGGAAAGGAATCAATG
CTAGACCCAAAACGTTTTTCATATAATAGTAACCTTCCCTAGGTAAACTTCGAAAAAAAT
TAGCATTAGAATTCCAACAATATGACTATTGTCGATTTATTTGAATAATACGATCCTAAT
AAAATTCCTAACTACTTAACAAATAATATTGATAAAATTCGCAAACATCTCGAATAAAGG
ATCCTAACTTTCAAAATACAAAATTACAGTTAATTTATAGTTAACGGTGAATAGTTAATA
AATGATGTCAGCTCTTACTCTAAGACAGAAGAAGTAAAAATGGTTGGCAGATTGATATCG
ACAGAAAATGGTTTTTTGAATACAACAAATTTAAGGATAGAACTTAATAGAAATCAATAT
TTCGATCTCGTCTTTGAAAACGATTTTGATTTTGGTAACAATGTTCTTTTTCCTAATTAG
ATAGTGATGGTTAAAGGTATCATAAATGAAAAAGAAGAATTAGTAGTAAGTGAGTTAATC
ACAGATCACATTAAGGAAATAACTGATGAAGAACATCCAAAAATTGATAATTTGAACTAA
GATGAAAGTTAGCTTATCATGGTAGCTGCAGGTCCTTTTTCTACTGTTATGTCTACTTAA
TATACATCATTTGATAACATTCTTCATGTTGCAAAGACTAAGAAAGTAAGCACTCTTATC
CTTCTTGGACCATTTTTAGATATAAAGAATGAAATTTTAAAAGATGGCAGTATTATAATA
AATAGCAAAGAATATACTTTTGAGTAATTGTAAAATTCCTTGTTTGAAAAAGCTGTAAAG
GAATTAGAAGGAAAAACTTAAATAATCATTGTCCCTTCTACTCGCGATATTCTTTCCACT
GACTCTATTCCTTAAATGAGTCTTGAAATTAAAGTTTCTGAACATAAGAATTCTATTCAC
TCTTACTCTAATCCAGCTTATATTGATATTGATAAATTAAGAGTTTACATTGCTAACTCA
GATGTCGGTATGATCACTCTTTAAAATAGTTTGTTAGATAAAAAGATTCCCTACATGCAG
CAATCACGTCTTACTTTTAAAGCACTTATGAATTAATAAAATTTGTACTCCATATATCCT
ATGAGAAATCCACAAGATTCATAATAAATATTAGAAACTGTAAAACTTCCTAATATAAAT
GATTTTGACATCCCTTTTGACTACTAGCTAGAATAATATCCTCATATAATTATCTCTCCT
TCATCTCTACCAAAATTTGCAACTAAAATCTATAATACCGTCGTCATAAATCCTAATTAT
GTTATACGTGATGGCTCATAAGCAGGAAATTTTGCTATAATTACTTTATTCAAAGATTCT
GACATTCCTATTCACGAAAGAACTCGTGTAGATTTATATTGTTTGTGA

>TTHERM_00614820(gene)
ATGGAAGAATTTGAAAAAATATTAGAAGAAATTGATTCTGCTAATTTAAGCCAAAATGCA
GTTTAATAATTGAAATAGTTAATTATTAGCAATGGAATATTAGATGATGAGTAATTAATG
GAAAAGTGGCTCTTTTAATTGGAGGCAATCATTTACAATAGCAAGTAAAAGTTTCTTGAA
GCTTAACTGATGGATTTTAAGAAGAATGTGCTTAATTAGGACATCAAAAAACCTCAAAAT
GACAATTTTAAAAAAATAAAGGAATCTGAAGTTTAAAAAAATATAGACATTATTAAAGGT
GATGCAGATTTATTTACTAAAGCTTCTTCAGCCAAAAAACAGACATCTACTTAATAAGCA
AATAATGCAGCAATTGATTGCGAAGAATAATTGCGTTAGTAGTTAGGAAAGGAATCAATG
CTAGACCCAAAACGTTTTTCATATAATAGTAACCTTCCCTAGGTAAACTTCGAAAAAAAT
TAGCATTAGAATTCCAACAATATGACTATTGTCGATTTATTTGAATAATACGATCCTAAT
AAAATTCCTAACTACTTAACAAATAATATTGATAAAATTCGCAAACATCTCGAATAAAGG
ATCCTAACTTTCAAAATACAAAATTACAGTTAATTTATAGTTAACGGTGAATAGTTAATA
AATGATGTCAGCTCTTACTCTAAGACAGAAGAAGTAAAAATGGTTGGCAGATTGATATCG
ACAGAAAATGGTTTTTTGAATACAACAAATTTAAGGATAGAACTTAATAGAAATCAATAT
TTCGATCTCGTCTTTGAAAACGATTTTGATTTTGGTAACAATGTTCTTTTTCCTAATTAG
ATAGTGATGGTTAAAGGTATCATAAATGAAAAAGAAGAATTAGTAGTAAGTGAGTTAATC
ACAGATCACATTAAGGAAATAACTGATGAAGAACATCCAAAAATTGATAATTTGAACTAA
GATGAAAGTTAGCTTATCATGGTAGCTGCAGGTCCTTTTTCTACTGTTATGTCTACTTAA
TATACATCATTTGATAACATTCTTCATGTTGCAAAGACTAAGAAAGTAAGCACTCTTATC
CTTCTTGGACCATTTTTAGATATAAAGAATGAAATTTTAAAAGATGGCAGTATTATAATA
AATAGCAAAGAATATACTTTTGAGTAATTGTAAAATTCCTTGTTTGAAAAAGCTGTAAAG
GAATTAGAAGGAAAAACTTAAATAATCATTGTCCCTTCTACTCGCGATATTCTTTCCACT
GACTCTATTCCTTAAATGAGTCTTGAAATTAAAGTTTCTGAACATAAGAATTCTATTCAC
TCTTACTCTAATCCAGCTTATATTGATATTGATAAATTAAGAGTTTACATTGCTAACTCA
GATGTCGGTATGATCACTCTTTAAAATAGTTTGTTAGATAAAAAGATTCCCTACATGCAG
CAATCACGTCTTACTTTTAAAGCACTTATGAATTAATAAAATTTGTACTCCATATATCCT
ATGAGAAATCCACAAGATTCATAATAAATATTAGAAACTGTAAAACTTCCTAATATAAAT
GATTTTGACATCCCTTTTGACTACTAGCTAGAATAATATCCTCATATAATTATCTCTCCT
TCATCTCTACCAAAATTTGCAACTAAAATCTATAATACCGTCGTCATAAATCCTAATTAT
GTTATACGTGATGGCTCATAAGCAGGAAATTTTGCTATAATTACTTTATTCAAAGATTCT
GACATTCCTATTCACGAAAGAACTCGTGTAGATTTATATTGTTTGTGA

>TTHERM_00614820(protein)
MEEFEKILEEIDSANLSQNAVQQLKQLIISNGILDDEQLMEKWLFQLEAIIYNSKQKFLE
AQLMDFKKNVLNQDIKKPQNDNFKKIKESEVQKNIDIIKGDADLFTKASSAKKQTSTQQA
NNAAIDCEEQLRQQLGKESMLDPKRFSYNSNLPQVNFEKNQHQNSNNMTIVDLFEQYDPN
KIPNYLTNNIDKIRKHLEQRILTFKIQNYSQFIVNGEQLINDVSSYSKTEEVKMVGRLIS
TENGFLNTTNLRIELNRNQYFDLVFENDFDFGNNVLFPNQIVMVKGIINEKEELVVSELI
TDHIKEITDEEHPKIDNLNQDESQLIMVAAGPFSTVMSTQYTSFDNILHVAKTKKVSTLI
LLGPFLDIKNEILKDGSIIINSKEYTFEQLQNSLFEKAVKELEGKTQIIIVPSTRDILST
DSIPQMSLEIKVSEHKNSIHSYSNPAYIDIDKLRVYIANSDVGMITLQNSLLDKKIPYMQ
QSRLTFKALMNQQNLYSIYPMRNPQDSQQILETVKLPNINDFDIPFDYQLEQYPHIIISP
SSLPKFATKIYNTVVINPNYVIRDGSQAGNFAIITLFKDSDIPIHERTRVDLYCL