Identifiers and Description

Gene Model Identifier

TTHERM_00616050

Standard Name

DRS1 (Aspartyl-tRNA synthetase 1)

Aliases

PreTt19154 | 85.m00147 | 3725.m00038

Description

DRS1 aspartyl-tRNA synthetase protein; aspartyl-tRNA synthetase family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cytoplasm (IEA) | GO:0005737

Molecular Function

• aminoacyl-tRNA ligase activity (IEA) | GO:0004812
• ATP binding (IEA) | GO:0005524
• nucleic acid binding (IEA) | GO:0003676
• nucleotide binding (IEA) | GO:0000166

Biological Process

• translation (IEA) | GO:0006412
• tRNA aminoacylation for protein translation (IEA) | GO:0006418

Domains

• ( PF00152 ) tRNA synthetases class II (D,
• ( PF00587 ) tRNA synthetase class II core
• ( PF01336 ) OB-fold nucleic acid binding domain
• ( TIGR00457 ) asparaginyl-tRNA synthetase
• ( TIGR00458 ) aspartyl-tRNA synthetase
• ( TIGR00459 ) aspartyl-tRNA synthetase
• ( TIGR00462 ) lysyl-tRNA synthetase-like protein GenX
• ( TIGR00499 ) lysyl-tRNA synthetase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_27181	0
	Description: None
Tetrahymena borealis	EI9_18334.1	9.997093137033517e-262
	Description: aspartyl-tRNA synthetase (631 aa)
Oxytricha	Contig8290.0.g58	9.997093137033517e-262
	Description: tRNA synthetases class II (D, K and N)
SGD	YLL018C	9.00303245425055e-177
	Description: DPS1 Aspartyl-tRNA synthetase, primarily cytoplasmic; homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation
DictyBase	DDB_G0272236	3.999622461503957e-161
	Description: aspS1 on chromosome: 2 position 1722204 to 1724012
WormBase	WBGene00001094	6.002643599093603e-161
	Description: locus:dars-1 Aspartate--tRNA ligase, cytoplasmic status:Confirmed UniProt:Q03577 protein_id:CAA79536.1

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00616050(coding)
ATGGCTGATAAAGTTGAAACCCCCGTTGTTGAAAAACAAGAAGAAACTGTCCCTGTTGAA
GGAGCTGCTAAGGAAGGTGGTGAAAATGCTTCTAAGAAAGCTCAAAAGAAGCTTGAAAAG
GAACAAGAAAAGGAAAGAAAGAGATTAGAAAGAGAAGCCGCCTAATTGAAGGAATAGGAG
GAAAATTGGCTTAAGGAACTCAAGGAAGATACTCTTAAGGAAAACTACGGAGATTATATC
CTTGTTCAAAGTCAAGAAAAGACTGACAGAAAGTGGATTTAGGTTTTGAGTATTGATGAA
TCAATGGTCGGTTAAACCGTCTTGATCAGAGCAAGACTCCAAAATTCTAGAGTTAAGGGT
AATGTCGGTTTCTTAGTTTTGAGATAACAATTTTCTACCATCCAAGCTATGATCTCTAAG
AACGACGTCACTGTTTCTAAGACCATGGTTAAATGGGTTGGTAAGGTTCCTTGTGAATCT
ATCGTTGATGTTTACGGTGTTGTCTCTAAGCCTGAAACTGAAATTAAGAGTACTTCATGC
AAACTTGAATTGATTGTCAACAAGGTTTATGTTGTCTCTCGTTCAAGAGCTCAACTTCCT
TTCCAATTAGAAGATGCTGCTAGATAATAAAAGAAGGAAGAACAATTAGCTGAATACAAT
AACAATGAAGGTGATATTGAAGAATCTAAGGATAATTAAGCCAGTGTCTCCATTAAAACT
CGTTTAGATAACAGAATTATTGATTTAAGAACTCCTGCCAAGCAAGCTATTTTCAGATTA
CAATCTGGTATCTGCCAATTATTCCGTGAATACTTACTTTCATAAGATTTCGTTGAAATT
CACACTCCTAAGCTTATTGGTGGTTCTTCTGAAGGTGGTGCTAACATCTTCAAGTTGAAG
TATTTCGATAAGGATGCTTGTCTTGCTTAATCTCCTTAACTCTACAAGTAAATGTGTATC
TAATCTGACTTCGAAAGAGTCTTCGAAATAGGTCCCGTTTTCAGAGCTGAAAAATCATTC
ACCCATCGTCACATGTGTGAATTCACTGGTTTGGATATTGAAATGTCCATTAAAGAAAAC
TACCATGAGCTTCTTGATCTTATGGGTGATTTATTCGTCCACATCTTCAAGGGCTTAGAA
ACCAAATACAGCAAGGAAATCGAAGCTATTTAATAATAATTCCCCTTCGAACCTTTCAAA
ATTAAAACCCCTGTTGTTAAACTCACTTTCGAAGAAGGTTGCAAACTCTTAAAAGAAGCT
GGTATTGAATAAAACCCCTTAGAAGATTTAGATACTGTTACTGAAAAGAAGCTTGGTGAC
ATCGTCCGTGAAAAGTATGATACTGATTTCTATATGCTCCATAGATATCCTATCTCTGCT
AGACCTTTCTACACCATGCTTTGCCACGATGATCCTAACTACACTCTTTCTTACGATTTC
TTCATGAGAGGTTAAGAAATCACCTCAGGTGCCTAAAGAAATCACGACCCCGTTTCTCTC
GCTAAGCGTGCTGCTGAATGTGGTATCAATGTAGAAACTATTAAAGATTATATTGAATCT
ATGGCTTTCGGTGCTTATCCTCATGGTGGTTGTGGTATTGGTCTTGAAAGAGTTGTTTTC
CTCTACTGCGACCTTTACGATATTAGAAACGGTTGCTTATTCCCCAGAGATCCTAAAAGA
ATTGCTCCTTGA

>TTHERM_00616050(gene)
ATGGCTGATAAAGTTGAAACCCCCGTTGTTGAAAAACAAGAAGAAACTGTCCCTGTTGAA
GGAGCTGCTAAGGAAGGTGGTGAAAATGCTTCTAAGAAAGCTCAAAAGAAGCTTGAAAAG
GAACAAGAAAAGGAAAGAAAGAGATTAGAAAGAGAAGCCGCCTAATTGAAGGAATAGGAG
GAAAATTGGCTTAAGGAACTCAAGGAAGATACTCTTAAGGAAAACTACGGAGATTATATC
CTTGTTCAAAGTCAAGAAAAGACTGACAGAAAGTGGATTTAGGTATTTACTCATTCCTTA
TTACTTTATTTCATATTTTTAAAAGCTCATTTTCAACAACAAAAGTTCAAGTTTTTGTAT
CTTCTTTTGTAGCGCCACAAGCATAAACATAAAAAAGAGAAATACAATCAAATGAGTAAT
AAAAAATAGAAATGCATCAAGAAATTTTAGAAACTAATCTATAAATGCAAACATTTTATC
ATTTTATTAATAACTTTTATTTCTATAATGAATAGGTTTTGAGTATTGATGAATCAATGG
TCGGTTAAACCGTCTTGATCAGAGCAAGACTCCAAAATTCTAGAGTTAAGGGTAATGTCG
GTTTCTTAGTTTTGAGATAACAATTTTCTACCATCCAAGCTATGATCTCTAAGAACGACG
TCACTGTTTCTAAGACCATGGTTAAATGGGTTGGTAAGGTTCCTTGTGAATCTATCGTTG
ATGTTTACGGTGTTGTCTCTAAGCCTGAAACTGAAATTAAGAGTACTTCATGCAAACTTG
AATTGATTGTCAACAAGGTTTATGTTGTCTCTCGTTCAAGAGCTCAACTTCCTTTCCAAT
TAGAAGATGCTGCTAGATAATAAAAGAAGGAAGAACAATTAGCTGAATACAATAACAATG
AAGGTGATATTGAAGAATCTAAGGATAATTAAGCCAGTGTCTCCATTAAAACTCGTTTAG
ATAACAGAATTATTGATTTAAGAACTCCTGCCAAGCAAGCTATTTTCAGATTACAATCTG
GTATCTGCCAATTATTCCGTGAATACTTACTTTCATAAGATTTCGTTGAAATTCACACTC
CTAAGCTTATTGGTGGTTCTTCTGAAGGTGGTGCTAACATCTTCAAGTTGAAGTATTTCG
ATAAGGATGCTTGTCTTGCTTAATCTCCTTAACTCTACAAGTAAATGTGTATCTAATCTG
ACTTCGAAAGAGTCTTCGAAATAGGTCCCGTTTTCAGAGCTGAAAAATCATTCACCCATC
GTCACATGTGTGAATTCACTGGTTTGGATATTGAAATGTCCATTAAAGAAAACTACCATG
AGCTTCTTGATCTTATGGGTGATTTATTCGTCCACATCTTCAAGGGCTTAGAAACCAAAT
ACAGCAAGGAAATCGAAGCTATTTAATAATAATTCCCCTTCGAACCTTTCAAAATTAAAA
CCCCTGTTGTTAAACTCACTTTCGAAGAAGGTTGCAAACTCTTAAAAGAAGCTGGTATTG
AATAAAACCCCTTAGAAGATTTAGATACTGTTACTGAAAAGAAGCTTGGTGACATCGTCC
GTGAAAAGTATGATACTGATTTCTATATGCTCCATAGATATCCTATCTCTGCTAGACCTT
TCTACACCATGCTTTGCCACGATGATCCTAACTACACTCTTTCTTACGATTTCTTCATGA
GAGGTTAAGAAATCACCTCAGGTGCCTAAAGAAATCACGACCCCGTTTCTCTCGCTAAGC
GTGCTGCTGAATGTGGTATCAATGTAGAAACTATTAAAGATTATATTGAATCTATGGCTT
TCGGTGCTTATCCTCATGGTGGTTGTGGTATTGGTCTTGAAAGAGTTGTTTTCCTCTACT
GCGACCTTTACGATATTAGAAACGGTTGCTTATTCCCCAGAGATCCTAAAAGAATTGCTC
CTTGA

>TTHERM_00616050(protein)
MADKVETPVVEKQEETVPVEGAAKEGGENASKKAQKKLEKEQEKERKRLEREAAQLKEQE
ENWLKELKEDTLKENYGDYILVQSQEKTDRKWIQVLSIDESMVGQTVLIRARLQNSRVKG
NVGFLVLRQQFSTIQAMISKNDVTVSKTMVKWVGKVPCESIVDVYGVVSKPETEIKSTSC
KLELIVNKVYVVSRSRAQLPFQLEDAARQQKKEEQLAEYNNNEGDIEESKDNQASVSIKT
RLDNRIIDLRTPAKQAIFRLQSGICQLFREYLLSQDFVEIHTPKLIGGSSEGGANIFKLK
YFDKDACLAQSPQLYKQMCIQSDFERVFEIGPVFRAEKSFTHRHMCEFTGLDIEMSIKEN
YHELLDLMGDLFVHIFKGLETKYSKEIEAIQQQFPFEPFKIKTPVVKLTFEEGCKLLKEA
GIEQNPLEDLDTVTEKKLGDIVREKYDTDFYMLHRYPISARPFYTMLCHDDPNYTLSYDF
FMRGQEITSGAQRNHDPVSLAKRAAECGINVETIKDYIESMAFGAYPHGGCGIGLERVVF
LYCDLYDIRNGCLFPRDPKRIAP