Identifiers and Description

Gene Model Identifier

TTHERM_00621280

Standard Name

NHX2 (Sodium Hydrogen Exchanger 2)

Aliases

PreTt05125 | 86.m00157

Description

NHX2 transporter monovalent cation:proton antiporter-2 (CPA2) family protein; Sodium/hydrogen exchanger family protein; Cation/H+ exchanger, CPA1 family

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

  • ( PF00999 ) Sodium/hydrogen exchanger family

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No. Gene Name(s) Paragraph Text
2233 NHX2 NHX2 belongs in the family of sodium-hydrogen exchangers that act as antiporrters that maintain the pH of actively metabolizing cells by controlling the balance of sodium. THe antiporters have 10-12 regions on the N-terminus and a large cytoplasmic region on the C-terminus. The 10-12 transmembrane regions contain 2 highly conserved regions and most of the regions share identities within the family , while the large cytoplasmic region is noted to have little similarity with other members in the family. Paragraph by: Chris Fang and Deanna Liou (undergraduates) Keck Science Department, The Claremont Colleges

Associated Literature

No Data fetched for Associated Literature

Sequences 

>TTHERM_00621280(coding)
ATGTTTGGAGTAATCTTTTTAATTGTAGTTGTGCTAATCTTGTTCTATTTGATTGGAGGT
GGGCTCCTTGAGCACTATAAGATACACGTTATTCATGAAACAGGATTAGGTATCATTATG
GGTATGATTGTAGGATTTATTTTCTATCAAGCCGATTACGAATTCTACTCAAGTAGTATG
ATATTTGAAGGTGAGCTCTTCTTTTACTTTATCCTTCCACCCATTATTTTTGCAGGCGGT
TACAACTTGAAAAAGCGTCGTTTTTTCCAAAATTTCTTCTACATTAATATATATGGATTA
CTTGGTACTATAGTCAATTTCATAGTAGTATGGCTCTTAACTTATGCTGTTAACGAAGCA
GGTTTGATTCGTAGATATAGTGATTTTTCTCAGTCTGTAACATTATCAACAAGAGATATC
CTTCTGTTTTCTGCTACTATATGCGCTACAGATAGTGTAGCTGCCTTAGCTATGATTAAA
TCAGAGAAATATCCAAAATTATTTAGTGTTATTTTTGGTGAAGGCATGGTAAATGATTCT
GTATCAATTATTCTATATAAGGCTGTCTTGGATTTAGTTGGCGACTCATCTGAACCTCAG
CCTATAACTTTCACTTTCCTTAACTTCTTAAAGATGATTGGTGAATTCCTTAAAAACTCA
GTATGCAGTTTAGCTATTGGTCTTGGTTGGGGTCTCTTAGCTACTTTAGTCATGAAAAAA
TTTAGGTTTTTGACACATAATCCAGTAGTTGAAACAGTTGTTGTTTTACTATTTGGTTTT
GGTGCTTTCGCTTCTTCAGAAAACCTAGATATGTCTGGTGTCATTTCAATTTTAGTATGT
GGTATTATCATGTCTCATTACCTTTTCTATAACATATCATCAACTGGTAAAGTAACAACA
GGTGTCACTTTTTCAAGTATCTCTATTATTGCAGAATCAGCTCTTTATATCTATTTGGGT
ATCGTCTTCTGGTAAACAAAGGGAGATCCTCACAATCCAAGCTCTTATGCATGGTCATGG
ACTTTCTTACTCATTGAATTGGCTATTGCCTTTTTCGCTCGTTTTGTGAGTGTTTTTGTA
GTTTCTTGGATTTTCATGCTAATTAAGGGCAAATAAAAATGGAGATTAAATAGATATGAA
ATGGGTATTATTTGGTTTGCAGGTATTATTAGAGGAGCTATTGCTTTTGCATTGATTTAG
AATGTACCTTAAGATGATTCAAATCCTTAGGCAACACAAGTTATTTAGAGTACAACTCTC
TTTATTGTTATAATCACAACTATTGTCTTAGGAGGTCTAATGCCTTTTTATATAAATGTC
ATGCTGAAACAAATTTCAAAGAATCCTAAGTATCATGAAAATCATCCTTCTATTCGTGAT
AGTTTGGTTGGAGAATCAAAAGAAAGTAGAGAATTCAAAAGCAAGAGTCAGACAAAGTGG
AAATTATTTGATGAAAACTTTATCAAACCTTTGTTCATTTTCGACTATGAAAATAGAAAA
GAGCAAATTAAGATGGAAAAACAAAAGCTTAAAATGAACAGCTCACAGTTTGATGCTGGA
TATATAAAAGAATAGGAATAGGAAATGGGTCACCAAGAAAACGAAAATGAAGAAAATCAT
CAAGATTAACAAGATCAACAGCAACAAGAATTGCAAATTGGAAATGATAATGGCTAAGAA
GAAAATTTCAAATAAATATCCAGAGCAAACATGAATAAGCAAGCAGTTTAATCAATCAAT
TAAGATCCAGAAAATCATAGTAGTAATGAACATATTTGA



>TTHERM_00621280(gene)
AAGTAAATTATTTAAGGTGCAAATAAAAGAAATTAAATACTCAAACAATAACTATAGGTA
AAGTTATCTGATAAGTAAAAAATTAAATCATAAAAGTTAATAATTTGCTTATATAAAAAA
AAAGCCAAATTCTTATCTATCTATCGATTTATCTTTCATCTGTTGGATTGTAATTGTATA
GACATAAAAAAACAGTAAGAGTAAAGCAGATTCTAAATAAATGTTTGGAGTAATCTTTTT
AATTGTAGTTGTGCTAATCTTGTTCTATTTGATTGGAGGTGGGCTCCTTGAGCACTATAA
GATACACGTTATTCATGAAACAGGATTAGGTATCATTATGGGTATGATTGTAGGATTTAT
TTTCTATCAAGCCGATTACGAATTCTACTCAAGTAGTATGATATTTGAAGGTGAGCTCTT
CTTTTACTTTATCCTTCCACCCATTATTTTTGCAGGCGGTTACAACTTGAAAAAGCGTCG
TTTTTTCCAAAATTTCTTCTACATTAATATATATGGATTACTTGGTACTATAGTCAATTT
CATAGTAGTATGGCTCTTAACTTATGCTGTTAACGAAGCAGGTTTGATTCGTAGATATAG
TGATTTTTCTCAGTCTGTAACATTATCAACAAGAGATATCCTTCTGTTTTCTGCTACTAT
ATGCGCTACAGATAGTGTAGCTGCCTTAGCTATGATTAAATCAGAGAAATATCCAAAATT
ATTTAGTGTTATTTTTGGTGAAGGCATGGTAAATGATTCTGTATCAATTATTCTATATAA
GGCTGTCTTGGATTTAGTTGGCGACTCATCTGAACCTCAGCCTATAACTTTCACTTTCCT
TAACTTCTTAAAGATGATTGGTGAATTCCTTAAAAACTCAGTATGCAGTTTAGCTATTGG
TCTTGGTTGGGGTCTCTTAGCTACTTTAGTCATGAAAAAATTTAGGTTTTTGACACATAA
TCCAGTAGTTGAAACAGTTGTTGTTTTACTATTTGGTTTTGGTGCTTTCGCTTCTTCAGA
AAACCTAGATATGTCTGGTGTCATTTCAATTTTAGTATGTGGTATTATCATGTCTCATTA
CCTTTTCTATAACATATCATCAACTGGTAAAGTAACAACAGGTGTCACTTTTTCAAGTAT
CTCTATTATTGCAGAATCAGCTCTTTATATCTATTTGGGTATCGTCTTCTGGTAAACAAA
GGGAGATCCTCACAATCCAAGCTCTTATGCATGGTCATGGACTTTCTTACTCATTGAATT
GGCTATTGCCTTTTTCGCTCGTTTTGTGAGTGTTTTTGTAGTTTCTTGGATTTTCATGCT
AATTAAGGGCAAATAAAAATGGAGATTAAATAGATATGAAATGGGTATTATTTGGTTTGC
AGGTATTATTAGAGGAGCTATTGCTTTTGCATTGATTTAGAATGTACCTTAAGATGATTC
AAATCCTTAGGCAACACAAGTTATTTAGAGTACAACTCTCTTTATTGTTATAATCACAAC
TATTGTCTTAGGAGGTCTAATGCCTTTTTATATAAATGTCATGCTGAAACAAATTTCAAA
GAATCCTAAGTATCATGAAAATCATCCTTCTATTCGTGATAGTTTGGTTGGAGAATCAAA
AGAAAGTAGAGAATTCAAAAGCAAGAGTCAGACAAAGTGGAAATTATTTGATGAAAACTT
TATCAAACCTTTGTTCATTTTCGACTATGAAAATAGAAAAGAGCAAATTAAGATGGAAAA
ACAAAAGCTTAAAATGAACAGCTCACAGTTTGATGCTGGATATATAAAAGAATAGGAATA
GGAAATGGGTCACCAAGAAAACGAAAATGAAGAAAATCATCAAGATTAACAAGATCAACA
GCAACAAGAATTGCAAATTGGAAATGATAATGGCTAAGAAGAAAATTTCAAATAAATATC
CAGAGCAAACATGAATAAGCAAGCAGTTTAATCAATCAATTAAGATCCAGAAAATCATAG
TAGTAATGAACATATTTGAAGTTGAATGTGAATTTAAAAATCTGTCTGAGATAAAAATAT
TAATATTAACAATAATAAATATCAAATTATAAAAACTTAAAACCTAATTTTAAATTTAAA
TATCGTAAAAAATTTATTTTAAAATTATACATACACAATTGTTAGTGTATTTATAAATTA
ATTTCATTAACTTAGTTCTAAATTATTTTCATTTCTCAAT



>TTHERM_00621280(protein)
MFGVIFLIVVVLILFYLIGGGLLEHYKIHVIHETGLGIIMGMIVGFIFYQADYEFYSSSM
IFEGELFFYFILPPIIFAGGYNLKKRRFFQNFFYINIYGLLGTIVNFIVVWLLTYAVNEA
GLIRRYSDFSQSVTLSTRDILLFSATICATDSVAALAMIKSEKYPKLFSVIFGEGMVNDS
VSIILYKAVLDLVGDSSEPQPITFTFLNFLKMIGEFLKNSVCSLAIGLGWGLLATLVMKK
FRFLTHNPVVETVVVLLFGFGAFASSENLDMSGVISILVCGIIMSHYLFYNISSTGKVTT
GVTFSSISIIAESALYIYLGIVFWQTKGDPHNPSSYAWSWTFLLIELAIAFFARFVSVFV
VSWIFMLIKGKQKWRLNRYEMGIIWFAGIIRGAIAFALIQNVPQDDSNPQATQVIQSTTL
FIVIITTIVLGGLMPFYINVMLKQISKNPKYHENHPSIRDSLVGESKESREFKSKSQTKW
KLFDENFIKPLFIFDYENRKEQIKMEKQKLKMNSSQFDAGYIKEQEQEMGHQENENEENH
QDQQDQQQQELQIGNDNGQEENFKQISRANMNKQAVQSINQDPENHSSNEHI