Identifiers and Description
Gene Model Identifier
TTHERM_00624720Standard Name
GRL4 (GRanule Lattice)Aliases
PreTt07460 | 87.m00240 | 3814.m00940Description
GRL4 granule lattice protein; Granule lattice protein; acidic- calcium-binding structural protein of dense core granules; translated as a pro-protein precursor; contains coiled-coil regionGenome Browser (Macronucleus)
Genome Browser (Micronucleus)
External Links
Gene Ontology Annotations
Cellular Component
- dense core granule (IDA) | GO:0031045
Biological Process
- exocytosis (IMP) | GO:0006887
Domains
No Data fetched for Domains
Gene Expression Profile
Vegetative Cell Cycle (Zhang et al., 2023)
GeneMania
Tetrahymena Stock Center
No Data fetched for Tetrahymena Stock Center
Homologs
Source Identifier Score Tetrahymena borealis EI9_12046.1 9.997093137033517e-262 Description: granule lattice protein 4 (377 aa) Tetrahymena borealis EI9_07015.1 9.997093137033517e-262 Description: hypothetical protein (181 aa) Oxytricha Contig761.1.g41 0.000005000363240844623 Description: Tetratricopeptide repeat
General Information
No Data fetched for General Information
Associated Literature
- Ref:15958493: Cowan AT, Bowman GR, Edwards KF, Emerson JJ, Turkewitz AP (2005) Genetic, genomic, and functional analysis of the granule lattice proteins in Tetrahymena secretory granules. Molecular biology of the cell 16(9):4046-60
- Ref:14690495: Turkewitz AP (2004) Out with a bang! Tetrahymena as a model system to study secretory granule biogenesis. Traffic (Copenhagen, Denmark) 5(2):63-8
- Ref:11438705: Chilcoat ND, Elde NC, Turkewitz AP (2001) An antisense approach to phenotype-based gene cloning in Tetrahymena. Proceedings of the National Academy of Sciences of the United States of America 98(15):8709-13
- Ref:9450970: Verbsky JW, Turkewitz AP (1998) Proteolytic processing and Ca2+-binding activity of dense-core vesicle polypeptides in Tetrahymena. Molecular biology of the cell 9(2):497-511
- Ref:9380694: Haddad A, Turkewitz AP (1997) Analysis of exocytosis mutants indicates close coupling between regulated secretion and transcription activation in Tetrahymena. Proceedings of the National Academy of Sciences of the United States of America 94(20):10675-80
Sequences
>TTHERM_00624720(coding)
ATGAGATACGCTGCTCTCTTCCTTCTTGCCTTAATCAGCTTCAACGCTGTTTATGCCGTC
TCTCTCAGAAAGAGCTCTGACGCCATGAAGACTTCTTTCGCTCTTGAAAGATTGAGATTC
ATCGGAAAGAAATCTCCTATTGCTAAACAAATTATCTCTGCTGTTGAATTACACTTAACC
ACTGGTGGTTTGGTTGATGATGTCATTGATTTAGTCAAGTAAGCCTAAGAAGATGTTGCC
AACAGAAACGTTGCTCTCCAAGCTGAATACACTGCCAAGAGAGGTGCTTTGGAAGATTAA
ATTAACACCACCACCTAATAACTCAATGAAGAAAACGACAGATTAGCTGTTGTTAACGAC
GCCATTGATGCCCTCAACGGTTAAATCGACAGTTTGAACACTCAAATTGCTAACCTCGTC
TAATAACTCTAAAACCTCTAAGCCAGAGAAGATGCTATCAACTAAGCCAGAGAAGTTGAT
GTCAAGACCTACGAAGTTAGAAAGTAAAGAGATGAAAACTCCCTCGCTGTCTTGGAATAA
ATCATCCAAAGATTACTTGCCTTATAACAAAGAGGTAACGCTTTCCTCCAAGTCTCCAAG
AAGGAAATCGAAAGAATCTTGAAGAGAATCCCCAAGTCCAACCCCATCCAAGCTTTGGTT
CAACTCTCCACCAAGTTCGACGAATAAAGATTAGCTGAAGTCATTAGCAAGCTCTAAACC
ATCTAAGCTGCCATCCAAGCTTCTTACATTGAAGATGCTAACGGTGAAGTTGCTGACAAG
TAAAGATACGATGCTCTCATTTAAGAAATCGCCACCATCAGAGCCCAAACTCAATAATAA
TTAGCTGATGCCTAATAAGCTTTGAGTGATGCTGAAGCTTCCTTAGCCTAATTCGTCCAA
GAATAAGGTAACTTACAACAACAAATCGCTGTCAACGAAGGTATCCTTGCTGATGCCCAA
GCTGCCTTAGCTCACACCATCGCTACCTACGAAGCTAGAATCCAAGAAGGTCAAGAAGCT
CTCGCCGCTATCAACCTTGCTCTCGATGTTTTACAACAAAACTAATCAGACTTATAAGGA
GTTGAAGATTTCTCTAATGCCTACAATGCCTACCAAGCTGGTAACAGTACTGATGCTGGT
GATGATGCTGGTGATGATTCTGGTGTTGAAGGTGAAGCTTTCTGA>TTHERM_00624720(gene)
ATGAGATACGCTGCTCTCTTCCTTCTTGCCTTAATCAGCTTCAACGCTGTTTATGCCGTC
TCTCTCAGAAAGAGCTCTGACGCCATGAAGACTTCTTTCGCTCTTGAAAGATTGAGATTC
GTAATGACTCACTTTCATATTATCATTTTCATCAAGGAGTGAACCACTTTTTCACAAAGT
CTTCATTTTTTTTTCGAATGACTAATTACTTTGTAAACCATAAATCTTAAAGTCAGTCGC
TCCTTGAAATACTTTGCTCTCATTTTAGAATAAAATATAACTAAAAATGAAAGAAAAAAC
AAATGCCCAAGCAATCTAACATAATTTCATATTATTTTCTACTTGATTGCTAATCTTATA
ATATCAAAATTTTTATTCAACCTGCCACAGTGCCTTTTTCCCCTTTTGATACATAAATAC
ATACATTCAATAAGCCGTTTTATTCAATAAAATTAATTTTAATAAAATTATAATATTATT
TATTTAAAATAAGATCGGAAAGAAATCTCCTATTGCTAAACAAATTATCTCTGCTGTTGA
ATTACACTTAACCACTGGTGGTTTGGTTGATGATGTCATTGATTTAGTCAAGTAAGCCTA
AGAAGATGTTGCCAACAGAAACGTTGCTCTCCAAGCTGAATACACTGCCAAGAGAGGTGC
TTTGGAAGATTAAATTAACACCACCACCTAATAACTCAATGAAGAAAACGACAGATTAGC
TGTTGTTAACGACGCCATTGATGCCCTCAACGGTTAAATCGACAGTTTGAACACTCAAAT
TGCTAACCTCGTCTAATAACTCTAAAACCTCTAAGCCAGAGAAGATGCTATCAACTAAGC
CAGAGAAGTTGATGTCAAGACCTACGAAGTTAGAAAGTAAAGAGATGAAAACTCCCTCGC
TGTCTTGGAATAAGTACTTGCTTGCTTTCTTTTTTGACTTTTTTTTTTAATAAAAATGAA
AATAATTCTAATTCTAAACTTTTTAAATAATAAAATAGATCATCCAAAGATTACTTGCCT
TATAACAAAGAGGTAACGCTTTCCTCCAAGTCTCCAAGAAGGAAATCGAAAGAATCTTGA
AGAGAATCCCCAAGTCCAACCCCATCCAAGCTTTGGTTCAACTCTCCACCAAGTTCGACG
AATAAAGATTAGCTGAAGTCATTAGCAAGCTCTAAACCATCTAAGCTGCCATCCAAGCTT
CTTACATTGAAGATGCTAACGGTGAAGTTGCTGACAAGTAAAGATACGATGCTCTCATTT
AAGAAATCGCCACCATCAGAGCCCAAACTCAATAATAATTAGCTGATGCCTAATAAGCTT
TGAGTGATGCTGAAGCTTCCTTAGCCTAATTCGTCCAAGAATAAGGTAACTTACAACAAC
AAATCGCTGTCAACGAAGGTATCCTTGCTGATGCCCAAGCTGCCTTAGCTCACACCATCG
CTACCTACGAAGCTAGAATCCAAGAAGGGTAATTAATTAATTGATTACATTTTTTAATAT
TAATTGTATTAACTTTTAATAACTTTCATATTTTTAAAAATTATAGTCAAGAAGCTCTCG
CCGCTATCAACCTTGCTCTCGATGTTTTACAACAAAACTAATCAGACTTATAAGGAGTTG
AAGATTTCTCTAATGCCTACAATGCCTACCAAGCTGGTAACAGTACTGATGCTGGTGATG
ATGCTGGTGATGATTCTGGTGTTGAAGGTGAAGCTTTCTGA>TTHERM_00624720(protein)
MRYAALFLLALISFNAVYAVSLRKSSDAMKTSFALERLRFIGKKSPIAKQIISAVELHLT
TGGLVDDVIDLVKQAQEDVANRNVALQAEYTAKRGALEDQINTTTQQLNEENDRLAVVND
AIDALNGQIDSLNTQIANLVQQLQNLQAREDAINQAREVDVKTYEVRKQRDENSLAVLEQ
IIQRLLALQQRGNAFLQVSKKEIERILKRIPKSNPIQALVQLSTKFDEQRLAEVISKLQT
IQAAIQASYIEDANGEVADKQRYDALIQEIATIRAQTQQQLADAQQALSDAEASLAQFVQ
EQGNLQQQIAVNEGILADAQAALAHTIATYEARIQEGQEALAAINLALDVLQQNQSDLQG
VEDFSNAYNAYQAGNSTDAGDDAGDDSGVEGEAF