Identifiers and Description

Gene Model Identifier

TTHERM_00624760

Standard Name

ATA2 (ATP Transport Apparatus 2 )

Aliases

PreTt07464 | 87.m00244 | 3814.m00945

Description

ATA2 ABC transporter family protein; hydrolyzes ATP as required energy for transport of ions and macromolecules across cellular membranes; ATP-binding cassette transporter C

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

  • ( PF00005 ) ABC transporter
  • ( PF00664 ) ABC transporter transmembrane region

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No. Gene Name(s) Paragraph Text
2252 ATA2 ATA2 from the eukaryote Tetrahymena thermophila is similar to ATA homologs from other eukaryotes. It contains two of each of the two types of domains, an ATP binding cassette (ABC) and a less conserved transmembrane domain (TMD), totaling four domains. The 3D structure of an ABC is a stubby L-shape with two distinct arms. These transporters function as dimers. The purpose of the binding cassettes (approximately 200 amino acid residues) is to bind and hydrolyze ATP, which releases energy that enables the transporters to transfer macromolecules and ions across cellular membranes. This most commonly occurs in the transport of essential nutrients to bacteria, but also is related to diseases such as cystic fibrosis in humans. It is clear that ATA2 is important as we can see that it is strongly conserved across many organisms from Homo sapiens to Drosophila. Paragraph provided by Aish Subramanian and Travis Tu at the Keck Science Department of Claremont McKenna, Pitzer, and Scripps Colleges.

Associated Literature

No Data fetched for Associated Literature

Sequences 

>TTHERM_00624760(coding)
ATGAGTGATTAACAAAGCTCTGCAACAAGGGACTCAATTGATATTGAAAGTTATCATTTA
TAGAAAGGATAAAAGCTATTGGATCAATCTTAAAATTTTAAATCTGAAAATCAATCAGAT
TCTTAATTTTAAAATGGGGCACTTAAAAATACAGATAAAAAAGGCTATAACTCATTTAGT
TAAGGCTATTCATGCATTTGGCGATTAATTTGGTTTCACTTTATAAGCATGGTTAAAAAA
TTAAAAAATATAGAATAACAAGGAAGAAGAATAGAAGTTGATGATCTGCCAGAGCTTGAA
GATCATGCTAAAGTAGAGTATACAGCTTACAAGTTGAAAGAAAAAATAGAAAAATTAGAC
CCTGAAAAAGTAACTTCTTTAGGGTTTTTGAAAATAATTGGATTGGCTTTCAAGAAAAGT
GTGTTGGCAATCATGACATTTTTATTTTTAGAGAATATAACTAAATTAATGGTTCCATAT
TGTATGCAAAAACTAATTTAACTTGTAAAAGAAGGTGATATTTAGTAAGCATCATTATGG
GTATTTTTACTTGTATTTTCGAGCTTTTTAGGGATTACATTTGGTTAAAATGGTTGGACA
GGCTCTTAAAGATTATGCGCTCAACTGAGATTAGGACTAATCAATATACTGTATTAAAAA
GTTAGTAACTTATCAGCTTTCTCAGTTAAAAAAGCTAATGTAGGAAAAATTATTAATATG
ATATCCTCTGATTTTAGTATTTTTGAAGTTAGAGCTGTGAATATATTCACCACAGCTTTA
GCTCCAATAACTTTATCTATTTCTTGTGGTATGCTTTGCTATAGAATTGGATATATTGCA
ATACCAGCCATTTTTCTTATGATAGGACTTTTTCCACTTTAAAAAAAAATAGCCTAAGCA
GCGTCTGAATATACAAAACAGTAGTCAAAGCATAGTGATTAAAAGATAAAGCTTTTTTCT
GAAATGATGGATGGTATAAGAATCATAAAAATGTATGGTTGGGAAAAAGCTTTTAATTCA
ACAATTAATAAGTTCAGAAGTTTAGAGGTAAGAAATACACTAATAAACCAAATTATTATG
TATATAGAGCATGCATTTAGTTTAAACGGTCCATTGTTTGTAGCTCTGCTTTGTTTTTTA
TTTATTGACATGTATGAAGATAACTTTCTTGATACTGCAATAATATTTTCAACCATTGAA
CTGATAAATTTAATCTCAAACACTATTATGAAGAATGTAGGTTATGGATTAAGTTTTATA
TTTGAGTTTAAAGTTCTTGTCTAAAGATATATGAGTGTTATATCTATTGAAAATGTATAG
ATGAAAAGCATTGATAATCCTCACATGAAACCCAACTTAGCAGATAATCCACCTTCTCCA
GATACACTTGTGTATATGAAAGATTTTTCAGCATATTGGTAGACTGAAGATTTAGAAAAT
CAAACACCTGTTTTGTAGGACATTAACTTTACAATCAAAAAAGGAGAAACTGTTTCTATC
ATTGGATAAATAGGAAGTGGAAAGACTTCCTTCCTTTTTGCTATAATGCAGGAGATACCT
CGCTATAAAGGTGTTTACTATTCTGTTTCTCAAATTTCCTTTGCCGAATAGGAACCCTTC
ATTCTTTAGGGAACTGTTAGAGATAACATTTTGTTTGGTAAGTCTTATGATGAAAAATTC
TACAAAAAAGTTGTCAAAGCTTGTTGTTTGCTTGATGATTACAAATAGTTTTCAAACGGA
GATCTAACAGTTGTTGGCGAAAGAGGTTCAAATTTAAGTGGAGGATAAAAAGCAAGAATA
TGTTTAGCAAGAGCAGTTTACGCAGATACAGATTTATATCTGTTAGATGACCCTCTTTCT
GCTGTAGACTCTAAAGTTGCTAAAAAAATATTCAAAAATGTTATAAATGGAATGCTCAAA
GACAAAGGAGTAATATTGGTCACACACTAGCTAAATTATGCTCTCAGATGTTAGAGGATT
GCAGTTTTCGAGAATGGAAATATTATTTTGTAGGGTAATCCTAATGAGATAAATTTCTCA
TAGACCTCTTTGGCAAAGCATATTGAGAATATTGAAAATCATCACGTAGAAGATGAAAAC
TAGTTAGATATTTCTATGGAATAGCAAATTCTTTAAGAAATTTAAAAGGAAGAGGATGAA
TAAGACAATGATGATGAAAATCAAGACAGTTCTACTAAATAAAAAGATATTCAAACTTTT
AAAAATGACAAAGAGATAAATAATGTTATTAAACCAAATGAAGATAGAAATTCTACTATT
TTCTCAAGCAGTGGAAAAAAGGAAGACGAATATCCAGTTACTAAAGATACATACATAAAT
TATTTCTTAACAAATCCTTCACCTTGGATATTTATGCTAGTAGTCTTTACATTTATTATT
TAGGAATTCCTATTTACTAGCTTTTACAAGTCTCTCTCGCTGTATGAATACGAATTTAAT
CGAGAATAATTCTATGCTATTTCTTTTGGAATCTTGACAGCATTTTTTGTATTTAAATTC
GTTTAATGCTCATTCATGTCTTACTTCGTATTACAGACAAATTAAAGTCTTACTTAAAAA
ATGATCAGAAGTATTTCTTAGGCTAGACCTATTTTATTTGATGAGATTCCTTCAGGACAA
ATCATAAATAAATATTCTACTGATATCTCAATATTAGATAAAAATTTGCCTGAAGCAGCC
CAATAAACAGTTGAAGGTGTATTGCACTTCATTAATCTAATTGGCTCTGTAATCTTCATT
AACTAGTATTTTATTATTCCTGGAGTTTTTGAAGTCTTTCTATTCTATAAATGGTTTAGA
TATATTAAACCAACTCTTATGCGTGCTAAGTAGCTAGATCTTGAAAATAAGACTCCAGTT
TTTCAATTTTTCTAAAGCTCTCTAAATGGCATTTTAATCATCAACATATATGGGCAAAAG
CAACTATTTTAATAAAAAATGGCTGTTCTTATGAATAATAGTATCAGGACAGCTGATATT
TTTTGGTTTGTTTCACGTTTGTTCAGTGTTAGCATGTAGTATTTTGCTTTAGCTGTTTCA
GGTGTTGGAATTTATATCATTTTATTCTTATCAAGCTCTGATAATCCCAAATTTGCAGAA
TCTTTAACCTATTTGCTGTTACTCACTAACTTTTTGCATATGACTTTGCGTGCTGTTATT
AATATGGACACTTTTATGACAAGTAGTGAACGTGCATGTTCTATAATAGATTTACCAAGA
GAAAATATTGAACTTAGTGATATTGACAGTGATTAATTAACCCACGATGATCACTAACAT
CATTAAACTTCATAAAATAGTTAAAGAAATAGGCATTATAACTAATTATAAAGTGAATAA
AGTTCGGTATCAATTGAAATAGAAGATTTTAACTAAGAGCGTTTAAACAAAAACTCAATA
TAAAGTAATAAATGGCCATCATAGGGCAATTTAAAATTTGATAATGTGTTTATGAGATAT
AAAGAAGGAATGAATCCAGTACTAAAAGGGGTAAGTTTTGAAGCTAAACCTCTAGAACGC
GTAGCTATTGTTGGGAGAACCGGAGCAGGAAAATCTTCCATTATTTAGGCTTTATTTAGA
ATGAGCGAAATAGACATTTCTTCAGAATAAGGACCTTCTCGCATATTTTATGATGATTAA
AATACAAGAGATGTGGGACTTCATTTACTAAGAAGAAGCATTAGCATTATCCCATAAAAT
CCTTTTGTTTTTAGTGGATCTATCCGCAGAAATATTGATCCGCTTGATGAATATACAGAT
CAATAAATCTATCATGTTTTAAGAGAAACTGGTTTAAATGAGTTAATATCAAAGCTTCCA
TAAGGTATAGAAACTGATATGAGTGACTCGGCATCAGTGTTCTCTATGGGACAAAGATAA
TTAGTTTGCCTAGCAAGAGTTATGCTTAGACGCAATAAGCTGATGGTTTTAGATGAAGCA
ACTGCAAATGTAGACATGGAAACTGACCACTTAATTTAGGAATTAATTAAGGAAAAATTC
TAAGATACAACTATAATAACAATAGCGCATAGACTAAATACTATCGCTGATTATGATAAA
ATTATTGTTTTGGATGCAGGTAAAGTTGTTGAAATCGATACTCCATTTAATTTACTTGCT
CTACGTGAGGAAGATTAAACTATTACTAACACTGAAAGTGTTTTTGCATAAATGGTACTA
AATACGGGTGCTAAAAATGGAGAGCAGATCTTCTAAATATGCAAGAAATCTTATCTTGAG
AAGAAAAAGAACATTTGA



>TTHERM_00624760(gene)
AAAATTTTGTTTATATTTCAATATAAATTAATAATAAGTAGGGAGGAGCTAACAAGTTTA
AAAAAATTTTTAATAAGGATAGATTTATTAAAAAGAAAGGAAATGAGTGATTAACAAAGC
TCTGCAACAAGGGACTCAATTGATATTGAAAGTTATCATTTATAGAAAGGATAAAAGCTA
TTGGATCAATCTTAAAATTTTAAATCTGAAAATCAATCAGATTCTTAATTTTAAAATGGG
GCACTTAAAAATACAGATAAAAAAGGCTATAACTCATTTAGTTAAGGCTATTCATGCATT
TGGCGATTAATTTGGTTTCACTTTATAAGCATGGTTAAAAAATTAAAAAATATAGAATAA
CAAGGAAGAAGAATAGAAGTTGATGATCTGCCAGAGCTTGAAGATCATGCTAAAGTAGAG
TATACAGCTTACAAGTTGAAAGAAAAAATAGAAAAATTAGACCCTGAAAAAGTAACTTCT
TTAGGGTTTTTGAAAATAATTGGATTGGCTTTCAAGAAAAGTGTGTTGGCAATCATGACA
TTTTTATTTTTAGAGAATATAACTAAATTAATGGTTCCATATTGTATGCAAAAACTAATT
TAACTTGTAAAAGAAGGTGATATTTAGTAAGCATCATTATGGGTATTTTTACTTGTATTT
TCGAGCTTTTTAGGGATTACATTTGGTTAAAATGGTTGGACAGGCTCTTAAAGATTATGC
GCTCAACTGAGATTAGGACTAATCAATATACTGTATTAAAAAGTTAGTAACTTATCAGCT
TTCTCAGTTAAAAAAGCTAATGTAGGAAAAATTATTAATATGATATCCTCTGATTTTAGT
ATTTTTGAAGTTAGAGCTGTGAATATATTCACCACAGCTTTAGCTCCAATAACTTTATCT
ATTTCTTGTGGTATGCTTTGCTATAGAATTGGATATATTGCAATACCAGCCATTTTTCTT
ATGATAGGACTTTTTCCACTTTAAAAAAAAATAGCCTAAGCAGCGTCTGAATATACAAAA
CAGTAGTCAAAGCATAGTGATTAAAAGATAAAGCTTTTTTCTGAAATGATGGATGGTATA
AGAATCATAAAAATGTATGGTTGGGAAAAAGCTTTTAATTCAACAATTAATAAGTTCAGA
AGTTTAGAGGTAAGAAATACACTAATAAACCAAATTATTATGTATATAGAGCATGCATTT
AGTTTAAACGGTCCATTGTTTGTAGCTCTGCTTTGTTTTTTATTTATTGACATGTATGAA
GATAACTTTCTTGATACTGCAATAATATTTTCAACCATTGAACTGATAAATTTAATCTCA
AACACTATTATGAAGAATGTAGGTTATGGATTAAGTTTTATATTTGAGTTTAAAGTTCTT
GTCTAAAGATATATGAGTGTTATATCTATTGAAAATGTATAGATGAAAAGCATTGATAAT
CCTCACATGAAACCCAACTTAGCAGATAATCCACCTTCTCCAGATACACTTGTGTATATG
AAAGATTTTTCAGCATATTGGTAGACTGAAGATTTAGAAAATCAAACACCTGTTTTGTAG
GACATTAACTTTACAATCAAAAAAGGAGAAACTGTTTCTATCATTGGATAAATAGGAAGT
GGAAAGACTTCCTTCCTTTTTGCTATAATGCAGGAGATACCTCGCTATAAAGGTGTTTAC
TATTCTGTTTCTCAAATTTCCTTTGCCGAATAGGAACCCTTCATTCTTTAGGGAACTGTT
AGAGATAACATTTTGTTTGGTAAGTCTTATGATGAAAAATTCTACAAAAAAGTTGTCAAA
GCTTGTTGTTTGCTTGATGATTACAAATAGTTTTCAAACGGAGATCTAACAGTTGTTGGC
GAAAGAGGTTCAAATTTAAGTGGAGGATAAAAAGCAAGAATATGTTTAGCAAGAGCAGTT
TACGCAGATACAGATTTATATCTGTTAGATGACCCTCTTTCTGCTGTAGACTCTAAAGTT
GCTAAAAAAATATTCAAAAATGTTATAAATGGAATGCTCAAAGACAAAGGAGTAATATTG
GTCACACACTAGCTAAATTATGCTCTCAGATGTTAGAGGATTGCAGTTTTCGAGAATGGA
AATATTATTTTGTAGGGTAATCCTAATGAGATAAATTTCTCATAGACCTCTTTGGCAAAG
CATATTGAGAATATTGAAAATCATCACGTAGAAGATGAAAACTAGTTAGATATTTCTATG
GAATAGCAAATTCTTTAAGAAATTTAAAAGGAAGAGGATGAATAAGACAATGATGATGAA
AATCAAGACAGTTCTACTAAATAAAAAGATATTCAAACTTTTAAAAATGACAAAGAGATA
AATAATGTTATTAAACCAAATGAAGATAGAAATTCTACTATTTTCTCAAGCAGTGGAAAA
AAGGAAGACGAATATCCAGTTACTAAAGATACATACATAAATTATTTCTTAACAAATCCT
TCACCTTGGATATTTATGCTAGTAGTCTTTACATTTATTATTTAGGAATTCCTATTTACT
AGCTTTTACAAGTCTCTCTCGCTGTATGAATACGAATTTAATCGAGAATAATTCTATGCT
ATTTCTTTTGGAATCTTGACAGCATTTTTTGTATTTAAATTCGTTTAATGCTCATTCATG
TCTTACTTCGTATTACAGACAAATTAAAGTCTTACTTAAAAAATGATCAGAAGTATTTCT
TAGGCTAGACCTATTTTATTTGATGAGATTCCTTCAGGACAAATCATAAATAAATATTCT
ACTGATATCTCAATATTAGATAAAAATTTGCCTGAAGCAGCCCAATAAACAGTTGAAGGT
GTATTGCACTTCATTAATCTAATTGGCTCTGTAATCTTCATTAACTAGTATTTTATTATT
CCTGGAGTTTTTGAAGTCTTTCTATTCTATAAATGGTTTAGATATATTAAACCAACTCTT
ATGCGTGCTAAGTAGCTAGATCTTGAAAATAAGACTCCAGTTTTTCAATTTTTCTAAAGC
TCTCTAAATGGCATTTTAATCATCAACATATATGGGCAAAAGCAACTATTTTAATAAAAA
ATGGCTGTTCTTATGAATAATAGTATCAGGACAGCTGATATTTTTTGGTTTGTTTCACGT
TTGTTCAGTGTTAGCATGTAGTATTTTGCTTTAGCTGTTTCAGGTGTTGGAATTTATATC
ATTTTATTCTTATCAAGCTCTGATAATCCCAAATTTGCAGAATCTTTAACCTATTTGCTG
TTACTCACTAACTTTTTGCATATGACTTTGCGTGCTGTTATTAATATGGACACTTTTATG
ACAAGTAGTGAACGTGCATGTTCTATAATAGATTTACCAAGAGAAAATATTGAACTTAGT
GATATTGACAGTGATTAATTAACCCACGATGATCACTAACATCATTAAACTTCATAAAAT
AGTTAAAGAAATAGGCATTATAACTAATTATAAAGTGAATAAAGTTCGGTATCAATTGAA
ATAGAAGATTTTAACTAAGAGCGTTTAAACAAAAACTCAATATAAAGTAATAAATGGCCA
TCATAGGGCAATTTAAAATTTGATAATGTGTTTATGAGATATAAAGAAGGAATGAATCCA
GTACTAAAAGGGGTAAGTTTTGAAGCTAAACCTCTAGAACGCGTAGCTATTGTTGGGAGA
ACCGGAGCAGGAAAATCTTCCATTATTTAGGCTTTATTTAGAATGAGCGAAATAGACATT
TCTTCAGAATAAGGACCTTCTCGCATATTTTATGATGATTAAAATACAAGAGATGTGGGA
CTTCATTTACTAAGAAGAAGCATTAGCATTATCCCATAAAATCCTTTTGTTTTTAGTGGA
TCTATCCGCAGAAATATTGATCCGCTTGATGAATATACAGATCAATAAATCTATCATGTT
TTAAGAGAAACTGGTTTAAATGAGTTAATATCAAAGCTTCCATAAGGTATAGAAACTGAT
ATGAGTGACTCGGCATCAGTGTTCTCTATGGGACAAAGATAATTAGTTTGCCTAGCAAGA
GTTATGCTTAGACGCAATAAGCTGATGGTTTTAGATGAAGCAACTGCAAATGTAGACATG
GAAACTGACCACTTAATTTAGGAATTAATTAAGGAAAAATTCTAAGATACAACTATAATA
ACAATAGCGCATAGACTAAATACTATCGCTGATTATGATAAAATTATTGTTTTGGATGCA
GGTAAAGTTGTTGAAATCGATACTCCATTTAATTTACTTGCTCTACGTGAGGAAGATTAA
ACTATTACTAACACTGAAAGTGTTTTTGCATAAATGGTACTAAATACGGGTGCTAAAAAT
GGAGAGCAGATCTTCTAAATATGCAAGAAATCTTATCTTGAGAAGAAAAAGAACATTTGA
AATATTAATTAAACACTGCTAATTTTAAGCAATCAGCTAATTTTTAAGTTTTGTTAATGC
TTTAAAAAATATAAAATATTGAAAAAGAAATTTAAAATATAGCTAAGGAAACTTAGTTTA
ATGCAAATGATAGAATTGGTGTAGTTTGGTTTTGTGTCTTTATAAATTTCATGTATTCTT
TATTAAAATATTTTAGATAGAATTAATCTTATAAAACAAA



>TTHERM_00624760(protein)
MSDQQSSATRDSIDIESYHLQKGQKLLDQSQNFKSENQSDSQFQNGALKNTDKKGYNSFS
QGYSCIWRLIWFHFISMVKKLKNIEQQGRRIEVDDLPELEDHAKVEYTAYKLKEKIEKLD
PEKVTSLGFLKIIGLAFKKSVLAIMTFLFLENITKLMVPYCMQKLIQLVKEGDIQQASLW
VFLLVFSSFLGITFGQNGWTGSQRLCAQLRLGLINILYQKVSNLSAFSVKKANVGKIINM
ISSDFSIFEVRAVNIFTTALAPITLSISCGMLCYRIGYIAIPAIFLMIGLFPLQKKIAQA
ASEYTKQQSKHSDQKIKLFSEMMDGIRIIKMYGWEKAFNSTINKFRSLEVRNTLINQIIM
YIEHAFSLNGPLFVALLCFLFIDMYEDNFLDTAIIFSTIELINLISNTIMKNVGYGLSFI
FEFKVLVQRYMSVISIENVQMKSIDNPHMKPNLADNPPSPDTLVYMKDFSAYWQTEDLEN
QTPVLQDINFTIKKGETVSIIGQIGSGKTSFLFAIMQEIPRYKGVYYSVSQISFAEQEPF
ILQGTVRDNILFGKSYDEKFYKKVVKACCLLDDYKQFSNGDLTVVGERGSNLSGGQKARI
CLARAVYADTDLYLLDDPLSAVDSKVAKKIFKNVINGMLKDKGVILVTHQLNYALRCQRI
AVFENGNIILQGNPNEINFSQTSLAKHIENIENHHVEDENQLDISMEQQILQEIQKEEDE
QDNDDENQDSSTKQKDIQTFKNDKEINNVIKPNEDRNSTIFSSSGKKEDEYPVTKDTYIN
YFLTNPSPWIFMLVVFTFIIQEFLFTSFYKSLSLYEYEFNREQFYAISFGILTAFFVFKF
VQCSFMSYFVLQTNQSLTQKMIRSISQARPILFDEIPSGQIINKYSTDISILDKNLPEAA
QQTVEGVLHFINLIGSVIFINQYFIIPGVFEVFLFYKWFRYIKPTLMRAKQLDLENKTPV
FQFFQSSLNGILIINIYGQKQLFQQKMAVLMNNSIRTADIFWFVSRLFSVSMQYFALAVS
GVGIYIILFLSSSDNPKFAESLTYLLLLTNFLHMTLRAVINMDTFMTSSERACSIIDLPR
ENIELSDIDSDQLTHDDHQHHQTSQNSQRNRHYNQLQSEQSSVSIEIEDFNQERLNKNSI
QSNKWPSQGNLKFDNVFMRYKEGMNPVLKGVSFEAKPLERVAIVGRTGAGKSSIIQALFR
MSEIDISSEQGPSRIFYDDQNTRDVGLHLLRRSISIIPQNPFVFSGSIRRNIDPLDEYTD
QQIYHVLRETGLNELISKLPQGIETDMSDSASVFSMGQRQLVCLARVMLRRNKLMVLDEA
TANVDMETDHLIQELIKEKFQDTTIITIAHRLNTIADYDKIIVLDAGKVVEIDTPFNLLA
LREEDQTITNTESVFAQMVLNTGAKNGEQIFQICKKSYLEKKKNI