Identifiers and Description

Gene Model Identifier

TTHERM_00629950

Standard Name

CTH125 (CaTHepsin 125)

Aliases

PreTt06517 | 89.m00111 | 3831.m01412

Description

CTH125 papain family cysteine protease; Peptidase C1A

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• obsolete integral component of mitochondrial membrane (IEA) | GO:0032592
• THO complex (IEA) | GO:0000347

Molecular Function

• 11-deoxycorticosterone binding (IEA) | GO:1903878
• 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity (IEA) | GO:0008413
• cytoskeletal anchor activity (IEA) | GO:0008093
• delta-type opioid receptor binding (IEA) | GO:0031850
• dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity (IEA) | GO:0106073
• fimbrial usher porin activity (IEA) | GO:0015473
• G protein-coupled serotonin receptor binding (IEA) | GO:0031821
• high-affinity secondary active nitrite transmembrane transporter activity (IEA) | GO:0015513
• interleukin-10 receptor binding (IEA) | GO:0005141
• L-gamma-glutamyl-L-propargylglycine hydroxylase activity (IEA) | GO:0062148
• lipopolysaccharide heptosyltransferase activity (IEA) | GO:0008920
• mercury ion transmembrane transporter activity (IEA) | GO:0015097
• nitrite efflux transmembrane transporter activity (IEA) | GO:0015514
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• phosphatidylserine decarboxylase activity (IEA) | GO:0004609
• sphingomyelin phosphodiesterase activity (IEA) | GO:0004767
• tumor necrosis factor receptor binding (IEA) | GO:0005164
• zinc efflux active transmembrane transporter activity (IEA) | GO:0015341

Biological Process

• auditory receptor cell fate commitment (IEA) | GO:0009912
• cell wall modification involved in fruit ripening (IEA) | GO:0009829
• cytoplasmic actin-based contraction involved in forward cell motility (IEA) | GO:0060328
• cytoplasmic actin-based contraction involved in rearward cell motility (IEA) | GO:0060329
• galactose to glucose-1-phosphate metabolic process (IEA) | GO:0061612
• glycolytic process from glycerol (IEA) | GO:0061613
• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• hexasaccharide transport (IEA) | GO:2001102
• macrophage derived foam cell differentiation (IEA) | GO:0010742
• maltohexaose transport (IEA) | GO:2001103
• muscle contraction (IEA) | GO:0006936
• negative regulation of complement-dependent cytotoxicity (IEA) | GO:1903660
• negative regulation of epithelial cell-cell adhesion involved in epithelium migration (IEA) | GO:1903682
• negative regulation of glyoxylate cycle (IEA) | GO:2000875
• negative regulation of L-glutamine biosynthetic process (IEA) | GO:0062133
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• negative regulation of phytoalexin metabolic process (IEA) | GO:0052321
• obsolete induction by virus of host cell-cell fusion (IEA) | GO:0006948
• ommochrome biosynthetic process (IEA) | GO:0006727
• phagocytosis (IEA) | GO:0006909
• pigment metabolic process involved in pigment accumulation (IEA) | GO:0043475
• plant-type cell wall modification (IEA) | GO:0009827
• positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction (IEA) | GO:0052330
• positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
• positive regulation of cap-independent translational initiation (IEA) | GO:1903679
• positive regulation of flower development (IEA) | GO:0009911
• positive regulation of forebrain neuron differentiation (IEA) | GO:2000979
• positive regulation of L-leucine biosynthetic process (IEA) | GO:2001278
• positive regulation of peroxisome proliferator activated receptor signaling pathway (IEA) | GO:0035360
• positive regulation of response to water deprivation (IEA) | GO:1902584
• positive regulation of stress response to copper ion (IEA) | GO:1903855
• positive regulation of tumor necrosis factor biosynthetic process (IEA) | GO:0042535
• positive regulation of wound healing, spreading of epidermal cells (IEA) | GO:1903691
• propan-2-ol biosynthetic process (IEA) | GO:1902640
• protein localization to old growing cell tip (IEA) | GO:1903858
• pteridine biosynthetic process (IEA) | GO:0006728
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
• regulation of complement-dependent cytotoxicity (IEA) | GO:1903659
• regulation of dendrite extension (IEA) | GO:1903859
• regulation of inner ear receptor cell differentiation (IEA) | GO:2000980
• regulation of macrophage derived foam cell differentiation (IEA) | GO:0010743
• regulation of muscle cell chemotaxis toward tendon cell (IEA) | GO:2001281
• regulation of phosphatidylcholine biosynthetic process (IEA) | GO:2001245
• regulation of sprouting angiogenesis (IEA) | GO:1903670
• regulation of unsaturated fatty acid biosynthetic process (IEA) | GO:2001279
• regulation of wound healing, spreading of epidermal cells (IEA) | GO:1903689
• tertiary alcohol biosynthetic process (IEA) | GO:1902645
• vitamin A metabolic process (IEA) | GO:0006776

Domains

• ( PF00112 ) Papain family cysteine protease
• ( PF08246 ) Cathepsin propeptide inhibitor domain (I29)

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00629950(coding)
ATGAAACTTTTACTTGGCTCTTTGATTTTAATTGGTTTGAGCTTATCTGCTTTGACCTAC
TTGAGTTTGGAAAAACCTCACCATGATCTCGAATCTATTCAAGATGTTAAACAACAATTC
GAAAAGTACTTATAGTAATTCGGTATTGTCATCAAGAATGCTGAAGAACGTATTTACAGA
TTGAAGGTCTTCATTTAAAACGTTGCTGAAATTGTTGCTCACAATAAGCTTTCCAACAAG
ACCTACACTCAAGGTATTAACTAATTCGCTCACATGACTGATGAAGAATTTGCTCAAACT
TATCTTACCCTTGAAGATCGTGAAAAGGAAACTCTTAACATCTAATAATTCTAATCAAAT
GATATCCCTGAATCTGTTGACTGGAGAACCTAGGGTGCTGTTACTGAAGTTAAAAACTAA
GGTGGCTGTGGTTCTTGCTACGCATTCTCTGCTGCTGGTGCTCTTGAAGGTCTCCACGCT
TAACAAACTGGAAACTTAACTAGCTTCTCATCTCAACAAATTATCGATTGCTCATGGAAA
TACCATAACCACGGATGCCACGGTGGTTTCATGGATAATGTTTTCAATTACGTTAAAGAT
CACGGTATTGAACTAGACTAAGACTATCCTTATGTTGGTCACGTCCACTTATTCAAATGC
TTGAATAACCCTGATGCTTACCACTATTCTATCAAGGGCCACTATGATATTAAGGCTGGT
GATTGCCAAGGTTTATAAGTAGCTATTGCTTAACAACCTGTTTCAGTTGCTATTGATGCT
AGAGTACTTAAGAAATACAGTTCTGGTATTGTTACTGAATGTGGTAGAAGAATTAAGCTT
AACCACGGTGTTTTGGCAGTTGGTTACGATGCTGATTCTTTAATTATCAAGAATTCTTGG
GGTACTAGATGGGGTGAATAAGGATACTTCAGACTTGGCAAGAATAACACTTGCGGTGTT
TGCTAAGCTGCTTCTTATCCTATCCCTCTTTGA

>TTHERM_00629950(gene)
ATTCTTTTATAATATAATAAATTCTTTAATAAAAGTACAAAATAATATTTACTCCCTAAT
GAGATTGCTTGTCACAGATCCTCTCATTGCTATATAAAATCATCATCTAACTTTTTAAAA
TTCTTATTATTATTTTAAATTAATTAATTAATAAAAATATAATTTGAAAATTTGTTTGTT
AATCAAATGAAACTTTTACTTGGCTCTTTGATTTTAATTGGTTTGAGCTTATCTGCTTTG
ACCTACTTGAGTTTGGAAAAACCTCACCATGATCTCGAATCTATTCAAGATGTTAAACAA
CAATTCGAAAAGTACTTATAGTAATTCGGTATTGTCATCAAGAATGCTGAAGAACGTATT
TACAGATTGAAGGTCTTCATTTAAAACGTTGCTGAAATTGTTGCTCACAATAAGCTTTCC
AACAAGACCTACACTCAAGGTATTAACTAATTCGCTCACATGACTGATGAAGAATTTGCT
CAAACTTATCTTACCCTTGAAGATCGTGAAAAGGAAACTCTTAACATCTAATAATTCTAA
TCAAATGATATCCCTGAATCTGTTGACTGGAGAACCTAGGGTGCTGTTACTGAAGTTAAA
AACTAAGGTGGCTGTGGTTCTTGCTACGCATTCTCTGCTGCTGGTGCTCTTGAAGGTCTC
CACGCTTAACAAACTGGAAACTTAACTAGCTTCTCATCTCAACAAATTATCGATTGCTCA
TGGAAATACCATAACCACGGATGCCACGGTGGTTTCATGGATAATGTTTTCAATTACGTT
AAAGATCACGGTATTGAACTAGACTAAGACTATCCTTATGTTGGTCACGTCCACTTATTC
AAATGCTTGAATAACCCTGATGCTTACCACTATTCTATCAAGGGCCACTATGATATTAAG
GCTGGTGATTGCCAAGGTTTATAAGTAGCTATTGCTTAACAACCTGTTTCAGTTGCTATT
GATGCTAGAGTACTTAAGAAATACAGTTCTGGTATTGTTACTGAATGTGGTAGAAGAATT
AAGCTTAACCACGGTGTTTTGGCAGTTGGTTACGATGCTGATTCTTTAATTATCAAGAAT
TCTTGGGGTACTAGATGGGGTGAATAAGGATACTTCAGACTTGGCAAGAATAACACTTGC
GGTGTTTGCTAAGCTGCTTCTTATCCTATCCCTCTTTGATTCAAATTAAATTGAAATTAT
AAATTTTAAAATGTATTAAATTTTTATAGCGTTGTCTAATTTTTTCAATAAAAAA

>TTHERM_00629950(protein)
MKLLLGSLILIGLSLSALTYLSLEKPHHDLESIQDVKQQFEKYLQQFGIVIKNAEERIYR
LKVFIQNVAEIVAHNKLSNKTYTQGINQFAHMTDEEFAQTYLTLEDREKETLNIQQFQSN
DIPESVDWRTQGAVTEVKNQGGCGSCYAFSAAGALEGLHAQQTGNLTSFSSQQIIDCSWK
YHNHGCHGGFMDNVFNYVKDHGIELDQDYPYVGHVHLFKCLNNPDAYHYSIKGHYDIKAG
DCQGLQVAIAQQPVSVAIDARVLKKYSSGIVTECGRRIKLNHGVLAVGYDADSLIIKNSW
GTRWGEQGYFRLGKNNTCGVCQAASYPIPL