Identifiers and Description

Gene Model Identifier

TTHERM_00633170

Standard Name

GPR37 (Gene Protein coupled Receptor 37)

Aliases

PreTt27986 | 90.m00150 | GPCR37

Description

7 transmembrane receptor (secretin family) protein; G protein coupled receptor; demonstrates chemorepellent receptor activity in the presence of conditioned supernatant factor

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• integral component of membrane (IEA) | GO:0016021

Molecular Function

• cAMP binding (IEA) | GO:0030552
• G protein-coupled receptor activity (IEA) | GO:0004930

Biological Process

• G protein-coupled receptor signaling pathway (IEA) | GO:0007186
• regulation of chemorepellent activity (IMP) | GO:1903667

Domains

• ( PF00001 ) 7 transmembrane receptor (rhodopsin family)
• ( PF00002 ) 7 transmembrane receptor (Secretin family)
• ( PF01534 ) Frizzled/Smoothened family membrane region
• ( PF05462 ) Slime mold cyclic AMP receptor

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

• ( SD01667 ) Macronucleus: GPCR3::neo3

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_15804.1	9.997093137033517e-262
	Description: 7 transmembrane receptor secretin family protein (328 aa)
DictyBase	DDB_G0283615	3.9992896861436003e-19
	Description: rpkA on chromosome: 4 position 1020192 to 1022856
Stentor Coeruleus	SteCoe_5578	4.248354255291589e-18
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:28685161: Zou D, Hennessey TM (2017) Behavioral Effects of a Chemorepellent Receptor Knockout Mutation in Tetrahymena thermophila. mSphere 2(4):

Sequences

>TTHERM_00633170(coding)
ATGACGATTGTTTCTAACCACAATTAGGTCAACATTATATAGATTATAGCTATTGTTGTC
AGCTCTTTTTCTCTTCTAGGAGCTATATTTATTATTGGAATATTTTTGAGTTTCAAAAAG
CTCAGGGTTTTCCCCTTTATATATGTCTTTTGGCTCAGTGTAAGTGACTTAATATCTTCT
ATAGGGTACCTTCTTGTTACTGACTCGATTGGAGACACTCCTGAATAGCTTCAAGAGGCA
AATTTTACTTGTAAAACTTAGGCTTTAATGATTAATTTTGGATAGCTTGCCTCTATTTGT
TGGACTGCAGTTATTGCCTGGACTCTCTACAACTCCACCGTTAAAGTGGTAACAAACTTA
CAACAAAAAACAGAAACAAAAATGGTTGCGATTGCTTTTGGATTTCCCCTAATTATGTCA
TTGATACCTTTAATTTTAAATGAATATGGCCCATAAGGAGGCTGGTGCTGGATAAAAAGT
GAAGGCAGCAATAAAGTATTAACATTTATTTTGGTAGGAATAGAATTTTATATTCCTCTT
TGGATAGCATTCGTATTTAATGGCATAACAATATACAGAGTAATCAAATATGTCAAGAGT
ATAACTCAAGATAAAAATTAGCTGAAACTAATCAATAGACTAACACTATATCCTCTTATT
TTATTGGTTTGCTGGAGTGCTGGTACCGTAGAAAGAGTATTTGATTTCATCGGTATCTCG
TCAGAGATACTTTCATATTTGCACATCTTCTTTGGTGGATTGTAAGGATTTTTTAATGCT
TGTGTTTACGGTCTCAATTCAAATGTCCGTAAAGTTATCAGAGAAAATCTATGCTCAAGC
CTACCATGCTTTGCAAGTGCATATATATATGAAGAATAAAACCTTAATGAAGCTGAAGAT
CATCAGCAAGATAGTAAAAAAACTGCATCCATATCCTCTGGCGAAGGCCAAGTTGAAATG
GAACAACTTAATCAATGA

>TTHERM_00633170(gene)
ATGACGATTGTTTCTAACCACAATTAGGTCAACATTATATAGATTATAGCTATTGTTGTC
AGCTCTTTTTCTCTTCTAGGAGCTATATTTATTATTGGAATATTTTTGAGTTTCAAAAAG
CTCAGGGTTTTCCCCTTTATATATGTCTTTTGGCTCAGTGTAAGTGACTTAATATCTTCT
ATAGGGTACCTTCTTGTTACTGACTCGATTGGAGACACTCCTGAATAGCTTCAAGAGGCA
AATTTTACTTGTAAAACTTAGGCTTTAATGATTAATTTTGGATAGCTTGCCTCTATTTGT
TGGACTGCAGTTATTGCCTGGACTCTCTACAACTCCACCGTTAAAGTGGTAACAAACTTA
CAACAAAAAACAGAAACAAAAATGGTTGCGATTGCTTTTGGATTTCCCCTAATTATGTCA
TTGATGTAATCATAATTTATTACTTACTTGAGAAAATTACGTTTTTCATACTATTAAAAT
ATCTTTAATACTTTGCTTTATTTATTAACTTTATGATAAATTAAATAGACCTTTAATTTT
AAATGAATATGGCCCATAAGGAGGCTGGTGCTGGATAAAAAGTGAAGGCAGCAATAAAGT
ATTAACATTTATTTTGGTAGGAATAGAATTTTATATTCCTCTTTGGATAGCATTCGTATT
TAATGGCATAACAATATACAGAGTAATCAAATATGTCAAGAGTATAACTCAAGATAAAAA
TTAGCTGAAACTAATCAATAGACTAACACTATATCCTCTTATTTTATTGGTTTGCTGGAG
TGCTGGTACCGTAGAAAGAGTATTTGATTTCATCGGTATCTCGTCAGAGATACTTTCATG
TAATTTATTTTTATTAAGCTATAGTAAAATAAGTAAAATTAATATTAATTTATTAATTTA
GATTTGCACATCTTCTTTGGTGGATTGTAAGGATTTTTTAATGCTTGTGTTTACGGTCTC
AATTCAAATGTCCGTAAAGTTATCAGAGAAAATCTATGCTCAAGCCTACCATGCTTTGCA
AGTGCATATATATATGAAGAATAAAACCTTAATGAAGCTGAAGATCATCAGCAAGATAGT
AAAAAAACTGCATCCATATCCTCTGGCGAAGGCCAAGTTGAAATGGAACAACTTAATCAA
TGA

>TTHERM_00633170(protein)
MTIVSNHNQVNIIQIIAIVVSSFSLLGAIFIIGIFLSFKKLRVFPFIYVFWLSVSDLISS
IGYLLVTDSIGDTPEQLQEANFTCKTQALMINFGQLASICWTAVIAWTLYNSTVKVVTNL
QQKTETKMVAIAFGFPLIMSLIPLILNEYGPQGGWCWIKSEGSNKVLTFILVGIEFYIPL
WIAFVFNGITIYRVIKYVKSITQDKNQLKLINRLTLYPLILLVCWSAGTVERVFDFIGIS
SEILSYLHIFFGGLQGFFNACVYGLNSNVRKVIRENLCSSLPCFASAYIYEEQNLNEAED
HQQDSKKTASISSGEGQVEMEQLNQ