Identifiers and Description

Gene Model Identifier

TTHERM_00636860

Standard Name

TRM1 (TRNA Methyltransferase 1)

Aliases

PreTt19689 | 91.m00104

Description

TRM1 N2-N2-dimethylguanosine tRNA methyltransferase; N2-N2-dimethylguanosine tRNA methyltransferase family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• obsolete tRNA (guanine-N2-)-methyltransferase activity (IEA) | GO:0004809
• RNA binding (IEA) | GO:0003723

Biological Process

• tRNA processing (IEA) | GO:0008033

Domains

• ( PF02005 ) N2,N2-dimethylguanosine tRNA methyltransferase
• ( PF04032 ) RNAse P Rpr2/Rpp21/SNM1 subunit domain
• ( PF07754 ) Small zinc finger protein HVO_2753-like, Zn-binding pocket
• ( TIGR00308 ) N2,N2-dimethylguanosine tRNA methyltransferase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_03510.1	9.997093137033517e-262
	Description: N2,N2-dimethylguanosine tRNA methyltransferase (598 aa)
Oxytricha	Contig10417.0.g41	2.9996277075259347e-88
	Description: N2,N2-dimethylguanosine tRNA methyltransferase
DictyBase	DDB_G0284575	1.0001267035975107e-72
	Description: DDB_G0284575 on chromosome: 4 position 2173651 to 2175465
WormBase	WBGene00006613	2.0007889996237956e-71
	Description: locus:trm-1 tRNA (guanine(26)-N(2))-dimethyltransferase status:Confirmed UniProt:Q23270 protein_id:CAB00881.1
WormBase	WBGene00009532	2.0007889996237956e-71
	Description: locus:ccch-1 status:Confirmed UniProt:Q20155 protein_id:CAA98475.2
SGD	YDR120C	6.9972728945133496e-59
	Description: TRM1 tRNA methyltransferase; two forms of the protein are made by alternative translation starts; localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments
Stentor Coeruleus	SteCoe_11063	3.6251409191435593e-34
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00636860(coding)
ATGTTAAAAAAAATCTTTAGCATAATTGGAAACTAATTAAACAAAAATAAATAAACAGTA
CTTCATAATCAAACTAATATTCAAGCAAAAAGGAGAACTTTTATTTTCGATTTTACAAAA
TATTTTAGAAAAATGGATAGCGAAGTTACAAACCAAATGTAAGTTGAGGAGGTTCCTTAA
TAGATAATTCAAGAAGAATCTAAATAGAATATTTAGTAGTAAATTACCAATTAACCAGTA
GATAATACCTTTATTTAGGAGGGATATGCTAAGATCTAAAAGTCTTACATTGAAAATTCA
GAAGATGGTAAAAAGTTGTTATCAGAAGTGTTCTACAACCCAGTTTAAGTTTTCAATAGA
GACTTAACTGTTTTGGTTATTCATATGTTCAAGGAATACTTAAAGGAAACTAGAAAGGAA
AAATTTGATGGAATAACTATTTTAGATGCTCTTTCTGCTAGTGGTCTTAGAGCAATTAGA
TTTAGCAAAGAACTTAAAGATATTAAGAAAGTCTATGCAAATGATATTTCCGAAGCATCC
CATAAGTTAATGATGGATAATTTCATATTGAACAATTTAGATCTTAGCAAAATTGAAATG
ACTTTAAAGGATGCCGTTTAGTTAATGTATGAATAAAAGTTCAGGAGCTCATCTGGAGAT
AGAAATGCTCGTTTTGATGTAATTGATTTAGATCCATATGGAACTTGTGCTCCATTCCTT
GACTGTGCCATTTAAGGCGCTGTTGGAGAAACATTACTATGCATTACTTCTACTGATTCT
AGAATCCTCTGTGGACCAGATACCTAAAAGTGCTACTATTTATATGGATCATCAAGAGCT
AAAATCGCTGCCTATGAAGAAAATGCAGTTAGAATTATTTTATATACAGCTAATAACATC
GCCAATAGATATGGAAAGTTTATTACACCTTTACTTTGTTACATGAGTGAATTTTATGTT
AGAGTCTTTCTTATAATCAAGCCTGGTAAACTTGAATGTGGAAGATCTTTAGTACGTACT
GGTAATGTTTTTCATTGTGATAACTGTTAGAATTAATACTTCCAAACATTTGGTAAGTAA
TCTAAGGCTAAGCAAAGTGATGCCCAAAAGCACGTTCCTTAAAAATTGAATCTTCCTAGC
AATATTTGCAATTAATGTGGAGAAAGCTTTACCATCAACGGACCTATTTGGACAGACAAA
TTGAATGATTAGGAATTCATCTAAAAAACTATTGATTATCTTAATTCAGATAAATTCGAT
TTACCTTTGGCTACTAAAAAGAAAATTGAAGGAATGTTGCACTCAATTTAGCTTGAGTAA
AAAGCTGGTGTTGATAATATTCCTTTAGGATTTAACTTTGAACACTTATCCAAGATGATG
AAAACTACAGTTCCAAGCAAAAAGAAAATTTTTTCAGCAATTAAAAGTTTAAATTATTCT
ATTGAATAAACATACTTAAATCCTGCTATATACAAAACAAATGCTCCTTCTGAAATAGTT
TTTGATGTTATCAGAAACTGGAAAAGAACCCTATAGCCAAATGATGAAGAATTCTTCAGG
GCATTTGATAAGGAAAGCTCTAATTATGCTATAGTCTCTAAACCAAACATATGCTAGCCC
AACTTCGATTTAGATATTAATGTTGAAAATAAACTACCAAGATGGCTTCCTAATCCAGAG
AAAAATTGGGGACCAGGAAAGAGACCTGCTCAAAAACTTCTAGTTGAAGAAGGATAAAAT
GAAGAAATCTAATAAGAACATTAGGATAATGGAGATGAATTAAAAAAGAAAAACAAAACA
GATTGA

>TTHERM_00636860(gene)
ATGTTAAAAAAAATCTTTAGCATAATTGGAAACTAATTAAACAAAAATAAATAAACAGTA
CTTCATAATCAAACTAATATTCAAGCAAAAAGGAGAACTTTTATTTTCGATTTTACAAAA
TATTTTAGAAAAATGGATAGCGAAGTTACAAACCAAATGTAAGTTGAGGAGGTTCCTTAA
TAGATAATTCAAGAAGAATCTAAATAGAATATTTAGTAGTAAATTACCAATTAACCAGTA
GATAATACCTTTATTTAGGAGGGATATGCTAAGATCTAAAAGTCTTACATTGAAAATTCA
GAAGATGGTAAAAAGTTGTTATCAGAAGTGTTCTACAACCCAGTTTAAGTTAATAACATT
AACACAGCAGCATTAAATTCAAAATGAGCTGAGCTAATTTGCTTATTTTTATTAGCTGTT
TATAAATTTTTTATCATCTTACTAAAGACATTTTTAATTATGATCATTAGGTTTTCAATA
GAGACTTAACTGTTTTGGTTATTCATATGTTCAAGGAATACTTAAAGGAAACTAGTAATT
AAATTTTGGAATTATTGAATTAAAGATTCTTAAAATATTAAGATAAAAATATTTTAAATT
AAATTTAGGAAAGGAAAAATTTGATGGAATAACTATTTTAGATGCTCTTTCTGCTAGTGG
TCTTAGAGCAATTAGATTTAGCAAAGAACTTAAAGATATTAAGAAAGTCTATGCAAATGA
TATTTCCGAAGCATCCCATAAGTTAATGATGGATAATTTCATATTGAACAATTTAGATCT
TAGCAAAATTGAAAGTAAAAACATCTTTTACATATTTTTTAACTCATAATATTAAATAAA
ATTGAGGTAGATAAATTCTTATTTTATAAATTATATTTAAGTGACTTTAAAGGATGCCGT
TTAGTTAATGTATGAATAAAAGTTCAGGAGCTCATCTGGAGATAGAAATGCTCGTTTTGA
TGTAATTGATTTAGATCCATATGGAACTTGTGCTCCATTCCTTGACTGTGCCATTTAAGG
CGCTGTTGGAGAAACATTACTATGCATTACTTCTACTGATTCTAGAATCCTCTGTGGACC
AGATACCTAAAAGTGCTACTATTTATATGGATCATCAAGAGCTAAAATCGCTGCCTATGA
AGAAGTAACTTTTAGATATTTTAAGGAAATTTTGAGTTAAATAAATGTATTATTAATTAA
TATAGAATGCAGTTAGAATTATTTTATATACAGCTAATAACATCGCCAATAGATATGGAA
AGTTTATTACACCTTTACTTTGTTACATGAGTGAATTTTATGTTAGAGTCTTTCTTATAA
TCAAGCCTGGTAAACTTGAATGTGGAAGATCTTTAGTACGTACTGGTAATGTTTTTCATT
GTGATAACTGTTAGAATTAATACTTCCAAACATTTGGTAAGTAATCTAAGGCTAAGCAAA
GTGATGCCCAAAAGCACGTTCCTTAAAAATTGAATCTTCCTAGCAATATTTGCAATTAAT
GTGGAGAAAGCTTTACCATCAGTAAATATTTAGCTTTGTATTTATTAAAATATAAAAAGA
ATTAAATTATTTATATTAATTATAAAGACGGACCTATTTGGACAGACAAATTGAATGATT
AGGAATTCATCTAAAAAACTATTGATTATCTTAATTCAGATAAATTCGATTTACCTTTGG
CTACTAAAAAGAAAATTGAAGGAATGTTGCACTCAATTTAGCTTGTAAAAACTAAATAAT
TTTGCAATTTATATAATTTTTATTAATAATTTTATAGGAGTAAAAAGCTGGTGTTGATAA
TATTCCTTTAGGATTTAACTTTGAACACTTATCCAAGATGATGAAAACTACAGTTCCAAG
CAAAAAGAAAATTTTTTCAGCAATTAAAAGTTTAAATTATTCTATTGAATAAACATACTT
AAATCCTGCTATATACAAAACAAATGCTCCTTCTGAAATAGTTTTTGATGTTATCAGAAA
CTGGGTAAAAATATATTTTTTTACTCATTCATTTATTTTATTTATAAGTTTTAGAAAGCT
AAAAAATTAATTAAATATTATAAAACAGAAAAGAACCCTATAGCCAAATGATGAAGAATT
CTTCAGGGCATTTGATAAGGAAAGCTCTAATTATGCTATAGTCTCTAAACCAAACATGTA
TTTGCTTAAATTTTACATATAATTAAAATACTATTTATAATTAAAAAAAATAGATGCTAG
CCCAACTTCGATTTAGATATTAATGTTGAAAATAAACTACCAAGATGGCTTCCTAATCCA
GAGAAAAATTGGGGACCAGGAAAGAGACCTGCTCAAAAGTAATTTTTATATCTTTCTTAT
AAGAGCTTTAACTAATTTTACTATGAATTGTTCTATTAAAAAGACTTCTAGTTGAAGAAG
GATAAAATGAAGAAATCTAATAAGAACATTAGGATAATGGAGATGAATTAAAAAAGAAAA
ACAAAACAGATTGA

>TTHERM_00636860(protein)
MLKKIFSIIGNQLNKNKQTVLHNQTNIQAKRRTFIFDFTKYFRKMDSEVTNQMQVEEVPQ
QIIQEESKQNIQQQITNQPVDNTFIQEGYAKIQKSYIENSEDGKKLLSEVFYNPVQVFNR
DLTVLVIHMFKEYLKETRKEKFDGITILDALSASGLRAIRFSKELKDIKKVYANDISEAS
HKLMMDNFILNNLDLSKIEMTLKDAVQLMYEQKFRSSSGDRNARFDVIDLDPYGTCAPFL
DCAIQGAVGETLLCITSTDSRILCGPDTQKCYYLYGSSRAKIAAYEENAVRIILYTANNI
ANRYGKFITPLLCYMSEFYVRVFLIIKPGKLECGRSLVRTGNVFHCDNCQNQYFQTFGKQ
SKAKQSDAQKHVPQKLNLPSNICNQCGESFTINGPIWTDKLNDQEFIQKTIDYLNSDKFD
LPLATKKKIEGMLHSIQLEQKAGVDNIPLGFNFEHLSKMMKTTVPSKKKIFSAIKSLNYS
IEQTYLNPAIYKTNAPSEIVFDVIRNWKRTLQPNDEEFFRAFDKESSNYAIVSKPNICQP
NFDLDINVENKLPRWLPNPEKNWGPGKRPAQKLLVEEGQNEEIQQEHQDNGDELKKKNKT
D