Identifiers and Description

Gene Model Identifier

TTHERM_00648920

Standard Name

HIAP1 (Histone-interacting acidic protein 1)

Aliases

PreTt09206 | 94.m00124 | 3677.m00032

Description

HIAP1 has several stretches of acidic residues similar to other histone chaperones, for example, human NPMs. This protein shares similarity with CNPL1 (NPM1 homologue in Tetrahymena) (Kanwal Ashraf et al., 2019).

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

  • ( PF03066 ) Nucleoplasmin/nucleophosmin domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_17846.1 3.998052787723392e-80
Description: hypothetical protein (277 aa)
Tetrahymena borealis EI9_18570.1 3.998052787723392e-80
Description: hypothetical protein (576 aa)

General Information

No. Gene Name(s) Paragraph Text
130 HIAP1 HIAP1 was identified as a high-confidence interacting partner of histones H2A/H2B and Hv1 in affinity purification followed by mass spectrometry experiments. HIAP1 shares sequence similarity with nucleoplasmin 1 (CNPL1 in Tetrahymena) due to stretches of acidic residues

Associated Literature

  1. Ref:30796450: Ashraf K, Nabeel-Shah S, Garg J, Saettone A, Derynck J, Gingras AC, Lambert JP, Pearlman RE, Fillingham J (2019) Proteomic analysis of histones H2A/H2B and variant Hv1 in Tetrahymena thermophila reveals an ancient network of chaperones. Molecular biology and evolution ( ):

Sequences 

>TTHERM_00648920(coding)
ATGTTTTGGGGAGCTTAAGTTCAGTTTAATCAAAAGTTTGTTCCAGAAAAGGAAGACTAT
GCTTATCTTCATTTAAGAAATGTTAGCACTTTATGGGCAAATGAAAAAATTAGCTTGGTT
TGCAATATTAAGAAGCAAGAAAACGGAGTCGAAGAAGAAATTGATATTGTTTTATGCCAT
TTAGATGAAAATAAAAATAGAAGTGCTCAGTTAAATCTTTACTTTGATTTAAAAAATTAA
GATATCAGCTTCAGTGTTATCGGAAAAGGAAGAGTCTGCTTGATGGGCTCTCTTGAGGCT
AAAGAGGGTAAGGCTCTCACAAACGAACTTGTAAAGAATTTAGGACCACAAATTGCTGAT
GCTAAAAAGAAAATGATTCTTGAGTTAGCAGGTCTTGTAAAAGATATGAAATAAAAAGGT
GGAAATCAAGAAGATGACGATGAGGATTTAGATGATGAAGAAGAATATGTAGAGGGTATG
GATCTTGAAAGTGATGATGAAGATGGTGAAGAAGATAACGAAGATGAAGAGGAAGTAGAA
AGTGAAATTAGTGATTAAGAAAATTAAATAGTAGAATAAAAAAAATCCTAATAAAGTCAA
AATCAATAAAAGAATAATAACAATAAAAATAATAAGTAAGCAAATAATTAGAACATTGGC
AAGAAGCCTATTTAAAACAAACCTGCTTAAAACTAAAATTAACAACAAAAGCAAAATAAA
TAGGAAAACAAAAATCAATAATAAAAAAACAATGGTTAGAATAAATAGTAAAATGGTAAG
AAAGGTGAATTCCAAATCACTTATAACTACAAACCTAAAAAGGAAGAAGAAATAGAAAAA
GACGAATTTGCTGCAATTTGA


>TTHERM_00648920(gene)
ATGTTTTGGGGAGCTTAAGTTCAGTTTAATCAAAAGTTTGTTCCAGAAAAGGAAGACTAT
GCTTATCTTCATTTAAGAAATGTTAGCACTTTATGGGCAAATGAAAAAATTAGCTTGGTT
TGCAATATTAAGAAGCAAGAAAACGGAGTCGAAGAAGAAATTGATATTGTTTTATGCCAT
TTAGATGAAAATAAAAATAGAAGTGCTCAGTTAAATCTTTACTTTGATTTAAAAAATTAA
GATATCAGCTTCAGTGTTATCGGAAAAGGAAGAGTCTGCTTGATGGGCTCTCTTGAGGCT
AAAGAGGGTAAGGCTCTCACAAACGAACTTGTAAAGAATTTAGGACCACAAATTGCTGAT
GCTAAAAAGAAAATGATTCTTGAGTTAGCAGGTCTTGTAAAAGATATGAAATAAAAAGGT
GGAAATCAAGAAGATGACGATGAGGATTTAGATGATGAAGAAGAATATGTAGAGGGTATG
GATCTTGAAAGTGATGATGAAGATGGTGAAGAAGATAACGAAGATGAAGAGGAAGTAGAA
AGTGAAATTAGTGATTAAGAAAATTAAATAGTAGAATAAAAAAAATCCTAATAAAGTCAA
AATCAATAAAAGAATAATAACAATAAAAATAATAAGTAAGCAAATAATTAGAACATTGGC
AAGAAGCCTATTTAAAACAAACCTGCTTAAAACTAAAATTAACAACAAAAGCAAAATAAA
TAGGAAAACAAAAATCAATAATAAAAAAACAATGGTTAGAATAAATAGTAAAATGGTAAG
AAAGGTGAATTCCAAATCACTTATAACTACAAACCTAAAAAGGAAGAAGAAATAGAAAAA
GACGAATTTGCTGCAATTTGA


>TTHERM_00648920(protein)
MFWGAQVQFNQKFVPEKEDYAYLHLRNVSTLWANEKISLVCNIKKQENGVEEEIDIVLCH
LDENKNRSAQLNLYFDLKNQDISFSVIGKGRVCLMGSLEAKEGKALTNELVKNLGPQIAD
AKKKMILELAGLVKDMKQKGGNQEDDDEDLDDEEEYVEGMDLESDDEDGEEDNEDEEEVE
SEISDQENQIVEQKKSQQSQNQQKNNNNKNNKQANNQNIGKKPIQNKPAQNQNQQQKQNK
QENKNQQQKNNGQNKQQNGKKGEFQITYNYKPKKEEEIEKDEFAAI